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The map label for this gene is aroF [H]

Identifier: 21673809

GI number: 21673809

Start: 929466

End: 930527

Strand: Direct

Name: aroF [H]

Synonym: CT0981

Alternate gene names: 21673809

Gene position: 929466-930527 (Clockwise)

Preceding gene: 21673808

Following gene: 21673810

Centisome position: 43.13

GC content: 54.8

Gene sequence:

>1062_bases
ATGCAACAACTACAGGATTTACGAGTTTCAAGAATCATTACTCTTAGCTCGCCAAAGGCACTGAAGGAAAAATTGCCCGT
AACGGAGCATATTGCCGATACGGTCTACAAGGCTAGGCAGGAAGTTGAGAATATTCTGACCGGCAAGGACAGCCGTATGC
TGGTCATCGTCGGCCCATGCTCCATTCACGACATCAAGGCGGCTCGTGACTATGCCTCGCGCCTTTTTGCTTTGCGCAAA
GAACTCGAATCGGAGTTCTGCATTGTCATGAGGGTTTATTTCGAGAAACCACGGACGACCATCGGCTGGAAAGGGTTCAT
CAACGACCCTCATCTCAACGATACCTACGATATCGAGCATGGCCTGTTCCATGCCCGAAAGCTGTTGATTGAGCTGAATG
AAATGGGCCTGCCCGCAGCCACGGAGTTTCTCGATCCGATCTCGCCGCAATATGTTGCTGACCTGATCAGCTGGGCAGCC
ATTGGCGCGCGTACCATCGAGTCACAGACTCACCGCCAGATGGCCAGTGGCCTGTCAATGCCGGTCGGTTTTAAAAACGC
GACCGATGGGCGCCTTCAGGTGGCCATCGACGCTATTCGGTCGGCGATGCACCAGCACAGTTTTCTCGGAATCGACCAAG
ACGGGCACAGCAGCGTCATCACCACCAAAGGGAACCCGTTTGGCCATCTCGTGCTGCGCGGCGGCTCTAGCAAGCCGAAC
TACGATGCCGACAGCATCGCCCATGCTGAAAAACAGTTGCGCAAGGCCGACCTGACTCCGCATCTGCTGGTCGATTGCAG
CCATGCTAACTCCGGCAAGAAGTGTGGTAATCAGCTCAAGGTCTGGGCCGATATTCTTGCCCAGAAGGAGCAGGGCAACA
CCAGCATCGTAGGGGTCATGATCGAGAGCAATATCTTCTCTGGAAACCAGCCTTTCCCGGTCGATCCGAGAGAGCTGCAA
TACGGCGTCTCGATTACCGACGAGTGCGTCTCTTGGGAGGAGACCGAGAGGATGCTTCGGGATGGAGCCGCATTCATGAA
GCAGGTTCGCTCGAAAGCCTGA

Upstream 100 bases:

>100_bases
GCCTGAGTGATAAGGAATTTACACGCGCAGCTTCCCGTTATTCTGGCTGAATTGTTATCTTCCAGACATAGTTAATTGAC
GATTTTTCTGAGTACTACGA

Downstream 100 bases:

>100_bases
TGGCTCAGCCGTCGAAAATTTTTATCAACCATAACCTTTCATCATTGCCATGAACATCGATAAAGCTGTCTACGCAGTTG
CGGGATTTTTTGTTATCGCC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MQQLQDLRVSRIITLSSPKALKEKLPVTEHIADTVYKARQEVENILTGKDSRMLVIVGPCSIHDIKAARDYASRLFALRK
ELESEFCIVMRVYFEKPRTTIGWKGFINDPHLNDTYDIEHGLFHARKLLIELNEMGLPAATEFLDPISPQYVADLISWAA
IGARTIESQTHRQMASGLSMPVGFKNATDGRLQVAIDAIRSAMHQHSFLGIDQDGHSSVITTKGNPFGHLVLRGGSSKPN
YDADSIAHAEKQLRKADLTPHLLVDCSHANSGKKCGNQLKVWADILAQKEQGNTSIVGVMIESNIFSGNQPFPVDPRELQ
YGVSITDECVSWEETERMLRDGAAFMKQVRSKA

Sequences:

>Translated_353_residues
MQQLQDLRVSRIITLSSPKALKEKLPVTEHIADTVYKARQEVENILTGKDSRMLVIVGPCSIHDIKAARDYASRLFALRK
ELESEFCIVMRVYFEKPRTTIGWKGFINDPHLNDTYDIEHGLFHARKLLIELNEMGLPAATEFLDPISPQYVADLISWAA
IGARTIESQTHRQMASGLSMPVGFKNATDGRLQVAIDAIRSAMHQHSFLGIDQDGHSSVITTKGNPFGHLVLRGGSSKPN
YDADSIAHAEKQLRKADLTPHLLVDCSHANSGKKCGNQLKVWADILAQKEQGNTSIVGVMIESNIFSGNQPFPVDPRELQ
YGVSITDECVSWEETERMLRDGAAFMKQVRSKA
>Mature_353_residues
MQQLQDLRVSRIITLSSPKALKEKLPVTEHIADTVYKARQEVENILTGKDSRMLVIVGPCSIHDIKAARDYASRLFALRK
ELESEFCIVMRVYFEKPRTTIGWKGFINDPHLNDTYDIEHGLFHARKLLIELNEMGLPAATEFLDPISPQYVADLISWAA
IGARTIESQTHRQMASGLSMPVGFKNATDGRLQVAIDAIRSAMHQHSFLGIDQDGHSSVITTKGNPFGHLVLRGGSSKPN
YDADSIAHAEKQLRKADLTPHLLVDCSHANSGKKCGNQLKVWADILAQKEQGNTSIVGVMIESNIFSGNQPFPVDPRELQ
YGVSITDECVSWEETERMLRDGAAFMKQVRSKA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=53.735632183908, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788953, Length=338, Percent_Identity=52.3668639053254, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1787996, Length=339, Percent_Identity=52.8023598820059, Blast_Score=370, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6319726, Length=347, Percent_Identity=51.2968299711816, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320240, Length=344, Percent_Identity=48.2558139534884, Blast_Score=338, Evalue=1e-93,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39320; Mature: 39320

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLQDLRVSRIITLSSPKALKEKLPVTEHIADTVYKARQEVENILTGKDSRMLVIVGPC
CCHHHHCCHHEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDIKAARDYASRLFALRKELESEFCIVMRVYFEKPRTTIGWKGFINDPHLNDTYDIEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCHHH
GLFHARKLLIELNEMGLPAATEFLDPISPQYVADLISWAAIGARTIESQTHRQMASGLSM
HHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVGFKNATDGRLQVAIDAIRSAMHQHSFLGIDQDGHSSVITTKGNPFGHLVLRGGSSKPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCC
YDADSIAHAEKQLRKADLTPHLLVDCSHANSGKKCGNQLKVWADILAQKEQGNTSIVGVM
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
IESNIFSGNQPFPVDPRELQYGVSITDECVSWEETERMLRDGAAFMKQVRSKA
EECCCCCCCCCCCCCHHHHEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQLQDLRVSRIITLSSPKALKEKLPVTEHIADTVYKARQEVENILTGKDSRMLVIVGPC
CCHHHHCCHHEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDIKAARDYASRLFALRKELESEFCIVMRVYFEKPRTTIGWKGFINDPHLNDTYDIEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCHHH
GLFHARKLLIELNEMGLPAATEFLDPISPQYVADLISWAAIGARTIESQTHRQMASGLSM
HHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVGFKNATDGRLQVAIDAIRSAMHQHSFLGIDQDGHSSVITTKGNPFGHLVLRGGSSKPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCC
YDADSIAHAEKQLRKADLTPHLLVDCSHANSGKKCGNQLKVWADILAQKEQGNTSIVGVM
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
IESNIFSGNQPFPVDPRELQYGVSITDECVSWEETERMLRDGAAFMKQVRSKA
EECCCCCCCCCCCCCHHHHEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]