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The map label for this gene is sglT [H]

Identifier: 21673803

GI number: 21673803

Start: 920544

End: 922304

Strand: Reverse

Name: sglT [H]

Synonym: CT0975

Alternate gene names: 21673803

Gene position: 922304-920544 (Counterclockwise)

Preceding gene: 21673804

Following gene: 21673802

Centisome position: 42.8

GC content: 60.82

Gene sequence:

>1761_bases
ATGGCACAACTCACCCCTCTGGACATCTCATTCATTGCGGGGTACCTGCTGTTGACCCTGCTGGTCGGCCTGTTCTTTTC
GCGACGGGCTTCTGAAAACGTCGGCGAGTTCTTCCTGTCAGGCCGCAAGCTGCCGTGGTGGATCGCTGGCACCGGCATGG
TTGCCACGACGTTCGCTGCCGATACGCCGCTTGCCGTCGCCGGATTTGTGGCCAAGAACGGCATCGCGGGCAACTGGGTG
TGGTGGACGTTCGTTTCGGGCGGAATGCTCACCGTCTTCTTCTTCGCCCGGCTCTGGCGGCGGGCAAACATTCTGACCGA
CCTCGAATTCATCGAGCTGCGCTACAGCGGCAAGGCTGCGAGCTTTCTGCGCGGCTTCAAGGCGGTCTATTTTGGCCTCT
TCATCAACGCGGTGATCATCGGGTGGGTAAACCTCGCCATGTTCAAGATCATCAAGATCATGATCCCCGGCCTCGACCCG
CAGCTCACCATCGTGGGGCTGGTGATTTTCACGGCGATCTACTCCGGCATGTCGGGCCTCTGGGGCGTCTCAATCACCGA
CGCCGTGCAGTTCGTCATCGCGATGGCTGGGTGCATCATCCTCGCCGTGCTGGCGGTCAACTCGCCGCAGGTCACGGCGG
CTGGCGGCCTCAAACAGGCGCTGCCGGACTGGATGTTCGACTTTTTCCCCTCGTTCTCCTCAACCGTCAACACATCGGCG
ACCGGAGCCTACGCCCTGCCCTTCACGGCCTTCGCGGCGATGGCGTTCGTGCAGTGGTGGGCGTCGTGGTATCCGGGCGC
GGAGCCGGGCGGCGGCGGCTATATCGCCCAACGCATGATGAGCGCCAAGGACGAAAAAAACTCGCTGTTGGCGACGCTCT
GGTTCACCATCGCGCACTATTGCGTTCGCCCGTGGCCGTGGATCGTGGTCGGTCTGGCGAGCCTCGTGATGTTCCCCAAT
CTTCCCGCTGGGCAGAAAGAGGACGGCTTCGTGCATGTCATGAATGCCGTGCTACCCGCCGGCTTGAAAGGCCTGCTCAT
CGCAGCCTTCATGGCAGCTTATATGTCCACCCTTTCGACCCATCTGAACTGGGGCACGAGCTACCTCATCAACGACCTCT
ACAAGCGCTTCATCAAGCGGGAGGCTGAACAGAACCACTACGTCTTGATGTCGCGGATCGTCACTGCGGTGACGGCTATC
TTCGCGCTTTACATCACGTTCTACGTGCTGGAGACCATCACCGGCGCGTGGGAGTTCATCATTCAGTGCGGCGCGGGCAC
GGGCTTCGTGCTCATCATGCGCTGGTTCTGGTGGCGGCTCAACGCCTGGTCAGAGATCACTTCGATGGTCGCGCCGATCG
TGGCCTACAGCTACATCAACCAGTTCACCACAATCGTCTTCCCCGAATCGATTTACATCATCGTCCTCTTCACGATTACC
TGCACCCTTGCGGTCACCTGGCTCACCAAACCAACTGACCGCGAGAAGCTGCACGCCTTCTACCGCACCACCCGCGTTGG
CGGCGCGCTCTGGAAACCGGTGGCCGACGAGATGCCCGACGTCAAGGGCGATACCGGTTTCCCCGCCCTCTTCGCCGACT
GGTTTTTCGGCATCGTGCTGGTTTACGCCACACTGTTCGGCACCGGCAAGCTGATCTTCGGCGAACCGGTGGCCGCCGCG
CTCTACTACGCCGCCGGCGCATTGGCAGGCGTGATGATCTACCGCGACCTGTCAAAGAGAAACTGGAAAACCTTCGATTG
A

Upstream 100 bases:

>100_bases
GGGGCATCCCGACAAGTCTCGATGCCCCTGCAGGTAACAACGCTATACTTCGTGGACAACCGCTGAAAAGACGCTCCGCC
ACCAAACCCAACACACGCCC

Downstream 100 bases:

>100_bases
CGATGACCTCACACCGCAAACTCATCCTCGCCTCGCAATCGCCGCGACGCCGGGAATTGCTCGCCATGACGGGAATTCCG
TTCGAGACCGCCTCGGTCGA

Product: sodium:solute symporter family protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MAQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAADTPLAVAGFVAKNGIAGNWV
WWTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAASFLRGFKAVYFGLFINAVIIGWVNLAMFKIIKIMIPGLDP
QLTIVGLVIFTAIYSGMSGLWGVSITDAVQFVIAMAGCIILAVLAVNSPQVTAAGGLKQALPDWMFDFFPSFSSTVNTSA
TGAYALPFTAFAAMAFVQWWASWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHYCVRPWPWIVVGLASLVMFPN
LPAGQKEDGFVHVMNAVLPAGLKGLLIAAFMAAYMSTLSTHLNWGTSYLINDLYKRFIKREAEQNHYVLMSRIVTAVTAI
FALYITFYVLETITGAWEFIIQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYSYINQFTTIVFPESIYIIVLFTIT
CTLAVTWLTKPTDREKLHAFYRTTRVGGALWKPVADEMPDVKGDTGFPALFADWFFGIVLVYATLFGTGKLIFGEPVAAA
LYYAAGALAGVMIYRDLSKRNWKTFD

Sequences:

>Translated_586_residues
MAQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAADTPLAVAGFVAKNGIAGNWV
WWTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAASFLRGFKAVYFGLFINAVIIGWVNLAMFKIIKIMIPGLDP
QLTIVGLVIFTAIYSGMSGLWGVSITDAVQFVIAMAGCIILAVLAVNSPQVTAAGGLKQALPDWMFDFFPSFSSTVNTSA
TGAYALPFTAFAAMAFVQWWASWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHYCVRPWPWIVVGLASLVMFPN
LPAGQKEDGFVHVMNAVLPAGLKGLLIAAFMAAYMSTLSTHLNWGTSYLINDLYKRFIKREAEQNHYVLMSRIVTAVTAI
FALYITFYVLETITGAWEFIIQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYSYINQFTTIVFPESIYIIVLFTIT
CTLAVTWLTKPTDREKLHAFYRTTRVGGALWKPVADEMPDVKGDTGFPALFADWFFGIVLVYATLFGTGKLIFGEPVAAA
LYYAAGALAGVMIYRDLSKRNWKTFD
>Mature_585_residues
AQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAADTPLAVAGFVAKNGIAGNWVW
WTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAASFLRGFKAVYFGLFINAVIIGWVNLAMFKIIKIMIPGLDPQ
LTIVGLVIFTAIYSGMSGLWGVSITDAVQFVIAMAGCIILAVLAVNSPQVTAAGGLKQALPDWMFDFFPSFSSTVNTSAT
GAYALPFTAFAAMAFVQWWASWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHYCVRPWPWIVVGLASLVMFPNL
PAGQKEDGFVHVMNAVLPAGLKGLLIAAFMAAYMSTLSTHLNWGTSYLINDLYKRFIKREAEQNHYVLMSRIVTAVTAIF
ALYITFYVLETITGAWEFIIQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYSYINQFTTIVFPESIYIIVLFTITC
TLAVTWLTKPTDREKLHAFYRTTRVGGALWKPVADEMPDVKGDTGFPALFADWFFGIVLVYATLFGTGKLIFGEPVAAAL
YYAAGALAGVMIYRDLSKRNWKTFD

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=420, Percent_Identity=24.7619047619048, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI109659836, Length=496, Percent_Identity=24.3951612903226, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4507031, Length=428, Percent_Identity=23.1308411214953, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI17941285, Length=474, Percent_Identity=24.0506329113924, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI109659839, Length=512, Percent_Identity=23.6328125, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI4507033, Length=435, Percent_Identity=22.9885057471264, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI110835708, Length=485, Percent_Identity=21.2371134020619, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI206597483, Length=433, Percent_Identity=23.3256351039261, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 64940; Mature: 64809

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCHHHHHCCC
DTPLAVAGFVAKNGIAGNWVWWTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAA
CCCHHHHHHHHHCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHCHHHHEEEECCCHH
SFLRGFKAVYFGLFINAVIIGWVNLAMFKIIKIMIPGLDPQLTIVGLVIFTAIYSGMSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
WGVSITDAVQFVIAMAGCIILAVLAVNSPQVTAAGGLKQALPDWMFDFFPSFSSTVNTSA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCC
TGAYALPFTAFAAMAFVQWWASWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CVRPWPWIVVGLASLVMFPNLPAGQKEDGFVHVMNAVLPAGLKGLLIAAFMAAYMSTLST
HHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HLNWGTSYLINDLYKRFIKREAEQNHYVLMSRIVTAVTAIFALYITFYVLETITGAWEFI
HHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYSYINQFTTIVFPESIYIIVLFTIT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHH
CTLAVTWLTKPTDREKLHAFYRTTRVGGALWKPVADEMPDVKGDTGFPALFADWFFGIVL
HHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHH
VYATLFGTGKLIFGEPVAAALYYAAGALAGVMIYRDLSKRNWKTFD
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCHHHHHCCC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HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]