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The map label for this gene is aatB [H]

Identifier: 21673794

GI number: 21673794

Start: 910086

End: 911288

Strand: Direct

Name: aatB [H]

Synonym: CT0966

Alternate gene names: 21673794

Gene position: 910086-911288 (Clockwise)

Preceding gene: 21673793

Following gene: 21673795

Centisome position: 42.23

GC content: 58.1

Gene sequence:

>1203_bases
ATGAGCGTAGAGAGCTTTGAACGATTCCTGAGCCGCCGGGTGCTGAGCATGCAGGAGTCGCAGACGATGAAAATTACCGG
ACTGGCCAAGAAGATGCAGGCGGAAGGCAAGGATGTTGTGAGTCTTTCTGCGGGCGAACCGGACTTCCCGACTCCAGAGA
ATGTGTGTGAGGCGGGCATCGAGGCAATTAGAAAAGGCTTTACCCGTTATACGGCAAATTCCGGAATTCCTGAGCTGAAA
AAAGCGATCATCCGCAAACTCCAGCGCGACAATGGCTTGGAATACGCCGAAGATGAAATCATCGTTAGTAACGGTGGCAA
GCAGGCGCTCGCCAACACCTTCCTCGCGCTGTGCGACGAGGGTGACGAGGTGATCGTACCGGCGCCCTACTGGGTGAGCT
TTCCGGAGATGGCGCGCCTGGCCGAAGCGACGCCGGTGATCGTCGAAACCTCCATTGAGACCGGTTACAAAATGACGCCG
GAGCAACTCGCCGCGGCCATCACGCCGAAGACCCGGATTCTCGTGCTCAATTCGCCATCGAATCCCTCCGGCGCAGTTTA
CAACGAGGCCGAAGTACGTGCGCTCATGCAGGTGATTGAAGGCAAGGAGATTTTTGTGCTTTCCGACGAGATGTACGACA
TGATCTGTTATGGCGGTGTGCGCCCCTTCTCGCCTGCGAGGATTCCGGAGATGAAGCCGTGGGTGATCGTCAGCAACGGC
ACTTCCAAGAGCTACTCGATGACCGGTTGGCGGATCGGCTACCTGGCTGCGCCGAAGTGGATCATCAATGCGTGCGACAA
GATTCAGTCGCAGACCACCTCGAACGCCAACTCCATTGCGCAGAAGGCCGCCGTGGCCGCGCTCGATGGCGACCAGTCCA
TCGTCGAACAGCGCCGTGCCGAGTTCGAGAAGCGCCGCGACTTCATGTTCCGTGAGCTGAACACCATTTCCGGCATCGAA
TGCACGTTGCCGGAGGGCGCATTCTACATCTTCCCGTCCATCAAAGGCCTGCTCGGCAAAACCTTTGGCGGCAAGGTGAT
GAAGGACTCGACCGACGTCGCGGAGTACCTGCTCACCGAGCACTACGTGGCTACCGTGCCTGGTGATGCGTTCGGAGCGC
CGGAGAACCTGCGCCTGTCCTACGCGGCCTCTATCGAAGAGTTGGCTGAGGCGGTCAACCGCATCAGAAAAGCGTTCAGT
TAA

Upstream 100 bases:

>100_bases
AGCAAGTTTGTCCATCCCTACGTGCTCGACCAACTTTCGCGAAAAAGAGCGGAACGGCGGGCGCACTGATTTTTTTCAAT
TAACAACCAATTCTGCAAAG

Downstream 100 bases:

>100_bases
GCGCAGCCCATGCTGAAGGTTCGCCGGAGCTGGGCATATACTCGATGGTTTGGCTGGTATTCGCGCCGGCAGTTCCGGCG
GCATTTCCACTCGCTGAGAG

Product: aspartate aminotransferase, putative

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSVESFERFLSRRVLSMQESQTMKITGLAKKMQAEGKDVVSLSAGEPDFPTPENVCEAGIEAIRKGFTRYTANSGIPELK
KAIIRKLQRDNGLEYAEDEIIVSNGGKQALANTFLALCDEGDEVIVPAPYWVSFPEMARLAEATPVIVETSIETGYKMTP
EQLAAAITPKTRILVLNSPSNPSGAVYNEAEVRALMQVIEGKEIFVLSDEMYDMICYGGVRPFSPARIPEMKPWVIVSNG
TSKSYSMTGWRIGYLAAPKWIINACDKIQSQTTSNANSIAQKAAVAALDGDQSIVEQRRAEFEKRRDFMFRELNTISGIE
CTLPEGAFYIFPSIKGLLGKTFGGKVMKDSTDVAEYLLTEHYVATVPGDAFGAPENLRLSYAASIEELAEAVNRIRKAFS

Sequences:

>Translated_400_residues
MSVESFERFLSRRVLSMQESQTMKITGLAKKMQAEGKDVVSLSAGEPDFPTPENVCEAGIEAIRKGFTRYTANSGIPELK
KAIIRKLQRDNGLEYAEDEIIVSNGGKQALANTFLALCDEGDEVIVPAPYWVSFPEMARLAEATPVIVETSIETGYKMTP
EQLAAAITPKTRILVLNSPSNPSGAVYNEAEVRALMQVIEGKEIFVLSDEMYDMICYGGVRPFSPARIPEMKPWVIVSNG
TSKSYSMTGWRIGYLAAPKWIINACDKIQSQTTSNANSIAQKAAVAALDGDQSIVEQRRAEFEKRRDFMFRELNTISGIE
CTLPEGAFYIFPSIKGLLGKTFGGKVMKDSTDVAEYLLTEHYVATVPGDAFGAPENLRLSYAASIEELAEAVNRIRKAFS
>Mature_399_residues
SVESFERFLSRRVLSMQESQTMKITGLAKKMQAEGKDVVSLSAGEPDFPTPENVCEAGIEAIRKGFTRYTANSGIPELKK
AIIRKLQRDNGLEYAEDEIIVSNGGKQALANTFLALCDEGDEVIVPAPYWVSFPEMARLAEATPVIVETSIETGYKMTPE
QLAAAITPKTRILVLNSPSNPSGAVYNEAEVRALMQVIEGKEIFVLSDEMYDMICYGGVRPFSPARIPEMKPWVIVSNGT
SKSYSMTGWRIGYLAAPKWIINACDKIQSQTTSNANSIAQKAAVAALDGDQSIVEQRRAEFEKRRDFMFRELNTISGIEC
TLPEGAFYIFPSIKGLLGKTFGGKVMKDSTDVAEYLLTEHYVATVPGDAFGAPENLRLSYAASIEELAEAVNRIRKAFS

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=321, Percent_Identity=28.3489096573209, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI169881279, Length=321, Percent_Identity=28.3489096573209, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI56713254, Length=353, Percent_Identity=28.328611898017, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI56713256, Length=353, Percent_Identity=28.328611898017, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI169881281, Length=320, Percent_Identity=23.125, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=22.0159151193634, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=28.6842105263158, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1788722, Length=372, Percent_Identity=29.3010752688172, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788627, Length=388, Percent_Identity=27.5773195876289, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790797, Length=311, Percent_Identity=22.8295819935691, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787710, Length=305, Percent_Identity=24.2622950819672, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=25.0632911392405, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=418, Percent_Identity=22.0095693779904, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=418, Percent_Identity=22.0095693779904, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=23.3595800524934, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=22.2506393861893, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=343, Percent_Identity=23.9067055393586, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=340, Percent_Identity=22.6470588235294, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=366, Percent_Identity=23.224043715847, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646114, Length=366, Percent_Identity=23.224043715847, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573067, Length=366, Percent_Identity=23.224043715847, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573065, Length=366, Percent_Identity=23.224043715847, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI18859735, Length=383, Percent_Identity=23.7597911227154, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44008; Mature: 43877

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVESFERFLSRRVLSMQESQTMKITGLAKKMQAEGKDVVSLSAGEPDFPTPENVCEAGI
CCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHH
EAIRKGFTRYTANSGIPELKKAIIRKLQRDNGLEYAEDEIIVSNGGKQALANTFLALCDE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
GDEVIVPAPYWVSFPEMARLAEATPVIVETSIETGYKMTPEQLAAAITPKTRILVLNSPS
CCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCC
NPSGAVYNEAEVRALMQVIEGKEIFVLSDEMYDMICYGGVRPFSPARIPEMKPWVIVSNG
CCCCCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
TSKSYSMTGWRIGYLAAPKWIINACDKIQSQTTSNANSIAQKAAVAALDGDQSIVEQRRA
CCCCEECCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
EFEKRRDFMFRELNTISGIECTLPEGAFYIFPSIKGLLGKTFGGKVMKDSTDVAEYLLTE
HHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
HYVATVPGDAFGAPENLRLSYAASIEELAEAVNRIRKAFS
CEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVESFERFLSRRVLSMQESQTMKITGLAKKMQAEGKDVVSLSAGEPDFPTPENVCEAGI
CHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHH
EAIRKGFTRYTANSGIPELKKAIIRKLQRDNGLEYAEDEIIVSNGGKQALANTFLALCDE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
GDEVIVPAPYWVSFPEMARLAEATPVIVETSIETGYKMTPEQLAAAITPKTRILVLNSPS
CCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCC
NPSGAVYNEAEVRALMQVIEGKEIFVLSDEMYDMICYGGVRPFSPARIPEMKPWVIVSNG
CCCCCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
TSKSYSMTGWRIGYLAAPKWIINACDKIQSQTTSNANSIAQKAAVAALDGDQSIVEQRRA
CCCCEECCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
EFEKRRDFMFRELNTISGIECTLPEGAFYIFPSIKGLLGKTFGGKVMKDSTDVAEYLLTE
HHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
HYVATVPGDAFGAPENLRLSYAASIEELAEAVNRIRKAFS
CEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]