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The map label for this gene is 21673654

Identifier: 21673654

GI number: 21673654

Start: 784968

End: 785810

Strand: Direct

Name: 21673654

Synonym: CT0825

Alternate gene names: NA

Gene position: 784968-785810 (Clockwise)

Preceding gene: 21673653

Following gene: 21673656

Centisome position: 36.43

GC content: 60.85

Gene sequence:

>843_bases
ATGGTCGGAGACGGCCATCCGGTGTATGTGATCGCAGAGATCGGAATCAACCACAACGGCTCGCTCGAAGTAGCCAAAAA
GCTGATCGAAGGCGCGGCGCAGGCAGGCTGCGATGCGGTCAAGTTCCAGAAACGGACGCCCGAGCTGTGCGTGCCGATGG
ACCAGCGCCTGATCGAGCGCGATACGCCGTGGGGGCGCATGACCTACATGGATTATCGCTACAAGGTTGAGTTCGGTTTC
GAGGAGTATTCCGAGATCGATGCCTATTGCCGCGAAAAGGGAATTGCCTGGTTCGCTTCATGCTGGGACGAGGAGGCGGT
CGATTTCATGGAGCAGTTCAATCCGCCGTGTTACAAGGCGGCCTCTGCCTCGCTGACCGATCTTACCCTGCTGAAAAAGA
CCAAGGCGACGGGGCGCCCGCTCATCATCTCGACCGGCATGTCCACCATGGAGGAGGTCGATGCCGCCGTCAACGAGCTT
GGCCGCGAGAATCTGCTGATCGCGCACACCAACTCTACCTATCCCTGCCCGGTCGAGGAGCTGAACCTGCGGATGATCCA
CACCCTGCAACAGCGTTATCCCGATAACCCCATCGGCTACTCCGGCCACGAGGTTGGCCTTGCCACGACATGGGCGGCGG
TGGCTCTCGGCGCGACCTTCGTGGAGCGCCACGTAACGCTCGACCGCGCCATGTGGGGTTCCGACCAGGCCGCGTCGGTG
GAGATTTCCGGCATGTCGAGGCTGGTCTCGAACATCCGCGACATCGAAAAAGCGCTCGGCGACGGTGTCAAGCGAGTCTA
TGATGGTGAAGCCGCCGCGCGCAAGAAGCTCAGAAGGGTATAG

Upstream 100 bases:

>100_bases
TTTTTTCCCGTATTAAGAGAATCAACCGCCGTCTTGTGGCGCGCTTTTTCATTATTTGACTGTACTGAAATCTATGGCTG
AAGTGAAAATCGGAAATAGC

Downstream 100 bases:

>100_bases
CCTGCAAGGATTTACGATCGAAATAGAGCCTGAAGCCGCAGAGGAGCCAAATCCTCTGCGGCTTTTTTTTTGTTGCGTCA
AGCGCGGGCGTAAAAGTCTT

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MVGDGHPVYVIAEIGINHNGSLEVAKKLIEGAAQAGCDAVKFQKRTPELCVPMDQRLIERDTPWGRMTYMDYRYKVEFGF
EEYSEIDAYCREKGIAWFASCWDEEAVDFMEQFNPPCYKAASASLTDLTLLKKTKATGRPLIISTGMSTMEEVDAAVNEL
GRENLLIAHTNSTYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFVERHVTLDRAMWGSDQAASV
EISGMSRLVSNIRDIEKALGDGVKRVYDGEAAARKKLRRV

Sequences:

>Translated_280_residues
MVGDGHPVYVIAEIGINHNGSLEVAKKLIEGAAQAGCDAVKFQKRTPELCVPMDQRLIERDTPWGRMTYMDYRYKVEFGF
EEYSEIDAYCREKGIAWFASCWDEEAVDFMEQFNPPCYKAASASLTDLTLLKKTKATGRPLIISTGMSTMEEVDAAVNEL
GRENLLIAHTNSTYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFVERHVTLDRAMWGSDQAASV
EISGMSRLVSNIRDIEKALGDGVKRVYDGEAAARKKLRRV
>Mature_280_residues
MVGDGHPVYVIAEIGINHNGSLEVAKKLIEGAAQAGCDAVKFQKRTPELCVPMDQRLIERDTPWGRMTYMDYRYKVEFGF
EEYSEIDAYCREKGIAWFASCWDEEAVDFMEQFNPPCYKAASASLTDLTLLKKTKATGRPLIISTGMSTMEEVDAAVNEL
GRENLLIAHTNSTYPCPVEELNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFVERHVTLDRAMWGSDQAASV
EISGMSRLVSNIRDIEKALGDGVKRVYDGEAAARKKLRRV

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=283, Percent_Identity=42.0494699646643, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI21357081, Length=256, Percent_Identity=39.453125, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 31219; Mature: 31219

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGDGHPVYVIAEIGINHNGSLEVAKKLIEGAAQAGCDAVKFQKRTPELCVPMDQRLIER
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHC
DTPWGRMTYMDYRYKVEFGFEEYSEIDAYCREKGIAWFASCWDEEAVDFMEQFNPPCYKA
CCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCHHHH
ASASLTDLTLLKKTKATGRPLIISTGMSTMEEVDAAVNELGRENLLIAHTNSTYPCPVEE
CCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
LNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFVERHVTLDRAMWGSDQAASV
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
EISGMSRLVSNIRDIEKALGDGVKRVYDGEAAARKKLRRV
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MVGDGHPVYVIAEIGINHNGSLEVAKKLIEGAAQAGCDAVKFQKRTPELCVPMDQRLIER
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHC
DTPWGRMTYMDYRYKVEFGFEEYSEIDAYCREKGIAWFASCWDEEAVDFMEQFNPPCYKA
CCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCHHHH
ASASLTDLTLLKKTKATGRPLIISTGMSTMEEVDAAVNELGRENLLIAHTNSTYPCPVEE
CCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
LNLRMIHTLQQRYPDNPIGYSGHEVGLATTWAAVALGATFVERHVTLDRAMWGSDQAASV
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
EISGMSRLVSNIRDIEKALGDGVKRVYDGEAAARKKLRRV
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]