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The map label for this gene is hupD [H]

Identifier: 21673610

GI number: 21673610

Start: 753005

End: 753469

Strand: Direct

Name: hupD [H]

Synonym: CT0780

Alternate gene names: 21673610

Gene position: 753005-753469 (Clockwise)

Preceding gene: 21673609

Following gene: 21673614

Centisome position: 34.94

GC content: 58.49

Gene sequence:

>465_bases
GTGGAGGTGGTTCGGGCGCTGGAGGCTTCCGGCGATTGGCCGGAAACGGTGCAGTTCGTGGATGGTGGCACGCAGGGACT
CTACTTGCTCGATTATTTCGAGTCATGCGATGCCTTGATGGTTTTCGACTCGATCATCCCGGTTGAGTTCGAGCCGAAGG
TCTATTGCTATCGTAAAGAAGAGCTACCCGCTTTCATTCACCGCAAAATGTCAGCTCATCAGATGGGTCTGAGCGAACTG
CTCGCCGTGGCCCGGCTGCATGGGCGGGAACCGTCGGAGATCGTGCTCATCGGTGCGCCACCGCACGATCTCGGACTGGG
CAACCCTCTGAGCGAGCCGATGCTCCGGCATCTGGCGCGGGCCGTCGAAACGGGACGCGAGTTGCTTGAAGAGTGGCTGG
TAAAAGTAAAGGCATCCGGTTTCCCTTGCGTTGCAGGGGATATCCGGATGCCTCATCGCTTTTAG

Upstream 100 bases:

>100_bases
GCTTTTTCCATAACTTTCATAATCTTTTAGTTTTTCCCCTGTGAAAACAATCAACGTAGTCGGTCTTGGCAATATTCTTT
TCGGTGATGAAGGTTTCGGC

Downstream 100 bases:

>100_bases
CTGTAAAGAAATGCTGACGTGTGGTCAGTGGTTGCCGATCAGGCGCAGGAACTCGCTTCGGGTAGACTGGCTGGTCATGA
AATCTCCGGACATGGCGGAG

Product: hydrogenase expression/formation protein HupD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MEVVRALEASGDWPETVQFVDGGTQGLYLLDYFESCDALMVFDSIIPVEFEPKVYCYRKEELPAFIHRKMSAHQMGLSEL
LAVARLHGREPSEIVLIGAPPHDLGLGNPLSEPMLRHLARAVETGRELLEEWLVKVKASGFPCVAGDIRMPHRF

Sequences:

>Translated_154_residues
MEVVRALEASGDWPETVQFVDGGTQGLYLLDYFESCDALMVFDSIIPVEFEPKVYCYRKEELPAFIHRKMSAHQMGLSEL
LAVARLHGREPSEIVLIGAPPHDLGLGNPLSEPMLRHLARAVETGRELLEEWLVKVKASGFPCVAGDIRMPHRF
>Mature_154_residues
MEVVRALEASGDWPETVQFVDGGTQGLYLLDYFESCDALMVFDSIIPVEFEPKVYCYRKEELPAFIHRKMSAHQMGLSEL
LAVARLHGREPSEIVLIGAPPHDLGLGNPLSEPMLRHLARAVETGRELLEEWLVKVKASGFPCVAGDIRMPHRF

Specific function: Not known. Could be involved in the processing of hydrogenase [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1787209, Length=115, Percent_Identity=43.4782608695652, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1789367, Length=103, Percent_Identity=35.9223300970874, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 17289; Mature: 17289

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVRALEASGDWPETVQFVDGGTQGLYLLDYFESCDALMVFDSIIPVEFEPKVYCYRKE
CHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEHHHCCCHHHHHHCCCCCEECCCEEEEECC
ELPAFIHRKMSAHQMGLSELLAVARLHGREPSEIVLIGAPPHDLGLGNPLSEPMLRHLAR
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
AVETGRELLEEWLVKVKASGFPCVAGDIRMPHRF
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MEVVRALEASGDWPETVQFVDGGTQGLYLLDYFESCDALMVFDSIIPVEFEPKVYCYRKE
CHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEHHHCCCHHHHHHCCCCCEECCCEEEEECC
ELPAFIHRKMSAHQMGLSELLAVARLHGREPSEIVLIGAPPHDLGLGNPLSEPMLRHLAR
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
AVETGRELLEEWLVKVKASGFPCVAGDIRMPHRF
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8230232; 8163174; 12597275 [H]