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The map label for this gene is fchA [H]

Identifier: 21673550

GI number: 21673550

Start: 702312

End: 702935

Strand: Direct

Name: fchA [H]

Synonym: CT0720

Alternate gene names: 21673550

Gene position: 702312-702935 (Clockwise)

Preceding gene: 21673549

Following gene: 21673554

Centisome position: 32.59

GC content: 61.54

Gene sequence:

>624_bases
ATGAAGTCTGACGGAACGCTCGGGTGGAGCGCAATCTCCACCTATCTCGACAGTCTTGCCAGCGCTGACCCCACTCCCGG
CGGCGGCGCGGCGGCGGCAGTCACGGCGGCACAAGGCGCGGCGCTGCTCTCGATGGTTTGCAACCTGACCATCGGCAAAA
AGAAGTTCGCCGATGTCGAGCATGAAGTCCACTCGATTCTCGACCAGTGCGAAACCGCCCGCCGCCAGATGCTCAACCTC
GGCGACCGCGACATGGAGGTGTTTGGCACGATCATGCAGATCTACAAGATGCCGAAAGCGACGCCGGAGGAGGCCGATGC
TCGCCGGGCTGCGATCCAGCAGGCGCTCAAGGCCAGCGCCGAAGTGCCGTTCGAGCTGTTCAAGCGCTGCCTGGCCATGT
TGCCTCTCGCAGATCGCCTCGAAAAGATTGGCAACCCCAAGGTGTTGAGTGACGTAATCGTTGGCCGCTATCTACTGGTT
GCCGGGCTGATGAGTGCCATGGCAAACGTCGAGGTCAACCTCGCCAGCATCGACGATGCCGAATTCTGCAAAGCCAAACG
CGAGGTTATGCTTCCAGCAATCGCAAGCATGGGCGTGAGCTGGCGGGGGCTGGCGGGCGTTTAA

Upstream 100 bases:

>100_bases
GAGGCCAAAGAGGCTGCGTCGCTTTACATTCCGAGGGTCGGCCCCATGACGGTGGCCATGTGTATGAGAAACGCCCTGCA
ACTCTATCACAACTACCACC

Downstream 100 bases:

>100_bases
TTGGATCTGACTGATTCGTCTGATCTGTCCGATTTTTAAACAAAAAAAGCCGCCCTTTTTCGGGCGGCTTTTTTGGCGTT
GATCCAGCGGTGAACCGCAG

Product: serine cycle enzyme, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKSDGTLGWSAISTYLDSLASADPTPGGGAAAAVTAAQGAALLSMVCNLTIGKKKFADVEHEVHSILDQCETARRQMLNL
GDRDMEVFGTIMQIYKMPKATPEEADARRAAIQQALKASAEVPFELFKRCLAMLPLADRLEKIGNPKVLSDVIVGRYLLV
AGLMSAMANVEVNLASIDDAEFCKAKREVMLPAIASMGVSWRGLAGV

Sequences:

>Translated_207_residues
MKSDGTLGWSAISTYLDSLASADPTPGGGAAAAVTAAQGAALLSMVCNLTIGKKKFADVEHEVHSILDQCETARRQMLNL
GDRDMEVFGTIMQIYKMPKATPEEADARRAAIQQALKASAEVPFELFKRCLAMLPLADRLEKIGNPKVLSDVIVGRYLLV
AGLMSAMANVEVNLASIDDAEFCKAKREVMLPAIASMGVSWRGLAGV
>Mature_207_residues
MKSDGTLGWSAISTYLDSLASADPTPGGGAAAAVTAAQGAALLSMVCNLTIGKKKFADVEHEVHSILDQCETARRQMLNL
GDRDMEVFGTIMQIYKMPKATPEEADARRAAIQQALKASAEVPFELFKRCLAMLPLADRLEKIGNPKVLSDVIVGRYLLV
AGLMSAMANVEVNLASIDDAEFCKAKREVMLPAIASMGVSWRGLAGV

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=139, Percent_Identity=31.6546762589928, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI11140815, Length=139, Percent_Identity=31.6546762589928, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22072; Mature: 22072

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSDGTLGWSAISTYLDSLASADPTPGGGAAAAVTAAQGAALLSMVCNLTIGKKKFADVE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HEVHSILDQCETARRQMLNLGDRDMEVFGTIMQIYKMPKATPEEADARRAAIQQALKASA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
EVPFELFKRCLAMLPLADRLEKIGNPKVLSDVIVGRYLLVAGLMSAMANVEVNLASIDDA
CCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHH
EFCKAKREVMLPAIASMGVSWRGLAGV
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKSDGTLGWSAISTYLDSLASADPTPGGGAAAAVTAAQGAALLSMVCNLTIGKKKFADVE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HEVHSILDQCETARRQMLNLGDRDMEVFGTIMQIYKMPKATPEEADARRAAIQQALKASA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
EVPFELFKRCLAMLPLADRLEKIGNPKVLSDVIVGRYLLVAGLMSAMANVEVNLASIDDA
CCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHH
EFCKAKREVMLPAIASMGVSWRGLAGV
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]