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The map label for this gene is pdxA [H]

Identifier: 21673426

GI number: 21673426

Start: 593241

End: 594245

Strand: Reverse

Name: pdxA [H]

Synonym: CT0591

Alternate gene names: 21673426

Gene position: 594245-593241 (Counterclockwise)

Preceding gene: 21673427

Following gene: 21673425

Centisome position: 27.58

GC content: 62.99

Gene sequence:

>1005_bases
ATGCACATCGTTTTTTCGACCGGCGACATTCACGGCATCGGCCCTGAAATCATCCTGAAAAGCGTGCTCGCGCTGCCTTC
GGGAGAGGACACCTACATGGTTGCCGGATCGTTGAAAGCGCTCGAATTCTACCGTGACCTGCTCGGCTTGCCAGTCGAGT
TGCGGCGAATCGAGGGGCCGGAGGCCATCGCGAAAATCGCGGCGGAGCCGGGCGTGCTGCACGTCCTGAGCGTCGCCGAG
CCGGACTTCATTCAGCCCGGCTCGCTCTCGAAAAGCGCGGGCGAGATCGCCATGCGCTCGCTCGAAACCGCCGCCACGTT
GTGCCGTGACGGCATCTGCGACGCGCTCGTCACCGCGCCGCTGCACAAAGAGGCAATTGCGCTCGCCGGGTACCGAAACA
CCGGCCACACCGATTTCCTCGCCGGATTTTTCGGCGTCTCGTCGCAAATCATGCTCTTCGTCGATCCCGTCTCCGGCCTC
AAGGTCGCACTGGCGACGATCCACGAACCGCTCTCGATGGTGCCGGAGCTGGTGCGAACGATGGATATGGACGGCTTTTT
CACCACGCTCGCCGGATCGATGCAGCGCGACTTCCGGCTCGAATCGCCAAAAATCGCCGTGCTCGGCCTCAACCCGCACG
CCTCGGACGGCGGCGTCATGGGCAATGAAGAGACAACAGTCATCCGTCCGGCAATCGAGCGGCTGGCGGCGTCGATGCAG
ATCGACGGGCCGTTTCCGGCGGACGGCTTTTTCGGCGCGAAACGCTACCGGAATTACGACCTCATCGTTGCCATGTACCA
CGACCAGGGGCTGCTTCCCTTCAAGGTGCTCGCCTTCGACACGGGCATCAACGTCACGCTCGGCCTGCCCATCGTGCGCA
CCTCGCCCGACCACGGCACCGGCTTCGACAAGGCGGGCAAGGGTACAGCCTCCGAACGCAGCTTTCTCGAAGCCGCCAAA
CTCGCCGCAACCATCGCAACGAACAGAACGCAAACCACAGGGTAA

Upstream 100 bases:

>100_bases
TCTCTTTATGCTGCTTCCCGAACCGGTACTCTTTTGGCTTGCCTTGCTCGGCGTCAAGAAGGACGAAAAAATCGCGACCG
CGTACAAAAGGCTCTGACAA

Downstream 100 bases:

>100_bases
CCCATGATCGCTTTCGTCAACGCAGACCTCGACATCAGAAAAAAGCCCATTTTCAGAAACCTGAACTTCACCATCCAGCC
CGGCGAACTGGTGTATATCG

Product: pyridoxal phosphate biosynthetic protein PdxA

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHIVFSTGDIHGIGPEIILKSVLALPSGEDTYMVAGSLKALEFYRDLLGLPVELRRIEGPEAIAKIAAEPGVLHVLSVAE
PDFIQPGSLSKSAGEIAMRSLETAATLCRDGICDALVTAPLHKEAIALAGYRNTGHTDFLAGFFGVSSQIMLFVDPVSGL
KVALATIHEPLSMVPELVRTMDMDGFFTTLAGSMQRDFRLESPKIAVLGLNPHASDGGVMGNEETTVIRPAIERLAASMQ
IDGPFPADGFFGAKRYRNYDLIVAMYHDQGLLPFKVLAFDTGINVTLGLPIVRTSPDHGTGFDKAGKGTASERSFLEAAK
LAATIATNRTQTTG

Sequences:

>Translated_334_residues
MHIVFSTGDIHGIGPEIILKSVLALPSGEDTYMVAGSLKALEFYRDLLGLPVELRRIEGPEAIAKIAAEPGVLHVLSVAE
PDFIQPGSLSKSAGEIAMRSLETAATLCRDGICDALVTAPLHKEAIALAGYRNTGHTDFLAGFFGVSSQIMLFVDPVSGL
KVALATIHEPLSMVPELVRTMDMDGFFTTLAGSMQRDFRLESPKIAVLGLNPHASDGGVMGNEETTVIRPAIERLAASMQ
IDGPFPADGFFGAKRYRNYDLIVAMYHDQGLLPFKVLAFDTGINVTLGLPIVRTSPDHGTGFDKAGKGTASERSFLEAAK
LAATIATNRTQTTG
>Mature_334_residues
MHIVFSTGDIHGIGPEIILKSVLALPSGEDTYMVAGSLKALEFYRDLLGLPVELRRIEGPEAIAKIAAEPGVLHVLSVAE
PDFIQPGSLSKSAGEIAMRSLETAATLCRDGICDALVTAPLHKEAIALAGYRNTGHTDFLAGFFGVSSQIMLFVDPVSGL
KVALATIHEPLSMVPELVRTMDMDGFFTTLAGSMQRDFRLESPKIAVLGLNPHASDGGVMGNEETTVIRPAIERLAASMQ
IDGPFPADGFFGAKRYRNYDLIVAMYHDQGLLPFKVLAFDTGINVTLGLPIVRTSPDHGTGFDKAGKGTASERSFLEAAK
LAATIATNRTQTTG

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=327, Percent_Identity=36.3914373088685, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35583; Mature: 35583

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIVFSTGDIHGIGPEIILKSVLALPSGEDTYMVAGSLKALEFYRDLLGLPVELRRIEGP
CEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCEEEEECCCH
EAIAKIAAEPGVLHVLSVAEPDFIQPGSLSKSAGEIAMRSLETAATLCRDGICDALVTAP
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LHKEAIALAGYRNTGHTDFLAGFFGVSSQIMLFVDPVSGLKVALATIHEPLSMVPELVRT
CCHHHEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
MDMDGFFTTLAGSMQRDFRLESPKIAVLGLNPHASDGGVMGNEETTVIRPAIERLAASMQ
HCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHEE
IDGPFPADGFFGAKRYRNYDLIVAMYHDQGLLPFKVLAFDTGINVTLGLPIVRTSPDHGT
CCCCCCCCCCCCHHHHCCCEEEEEEECCCCCCCEEEEEEECCCEEEECCEEEEECCCCCC
GFDKAGKGTASERSFLEAAKLAATIATNRTQTTG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHIVFSTGDIHGIGPEIILKSVLALPSGEDTYMVAGSLKALEFYRDLLGLPVELRRIEGP
CEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCEEEEECCCH
EAIAKIAAEPGVLHVLSVAEPDFIQPGSLSKSAGEIAMRSLETAATLCRDGICDALVTAP
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LHKEAIALAGYRNTGHTDFLAGFFGVSSQIMLFVDPVSGLKVALATIHEPLSMVPELVRT
CCHHHEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
MDMDGFFTTLAGSMQRDFRLESPKIAVLGLNPHASDGGVMGNEETTVIRPAIERLAASMQ
HCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHEE
IDGPFPADGFFGAKRYRNYDLIVAMYHDQGLLPFKVLAFDTGINVTLGLPIVRTSPDHGT
CCCCCCCCCCCCHHHHCCCEEEEEEECCCCCCCEEEEEEECCCEEEECCEEEEECCCCCC
GFDKAGKGTASERSFLEAAKLAATIATNRTQTTG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA