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The map label for this gene is fieF [H]

Identifier: 21673373

GI number: 21673373

Start: 544880

End: 546271

Strand: Reverse

Name: fieF [H]

Synonym: CT0538

Alternate gene names: 21673373

Gene position: 546271-544880 (Counterclockwise)

Preceding gene: 21673374

Following gene: 21673372

Centisome position: 25.35

GC content: 58.48

Gene sequence:

>1392_bases
ATGAGCAACCACGAAGAGAAAAAGCAACATGTCGCCCTCAGTTCGGTCGCGGCGAGCCTGTTGTTGACAGCGATGAAACT
CGTGGTCGGTCTCATGACCGGCAGCATCGGCATCCTCTCCGAGGCCGCGCACTCGGCGATAGATTTCGGCGCAGCGGCAC
TGACCTGGTTCGCCGTCAGAATCAGCGACAAACCGGCGGATAAAAAGCACCACTACGGACACACCAAAATCGAAAGCGTC
AGCGCACTCATCGAAACCGGCCTGCTGATACTCACCTCGGTCTGGATTATCTATGAGGCCGTGACGCGACTCCTTTCCGG
CACAACGGAGATCGAAGTCACCTGGTACGCTATCGCCGTTATCATTATCTCGATCATTGTGGATATATCGAGAGCTTCCG
CCCTGAAAAAAGTGGCCAAAGAGACCAAAAGCCAGGCCCTCGAAGCCGACGCGCTGCACTTCACCTCCGACATCGTCTCC
TCGGCGGTGGTGCTCGCGGGACTTGGCTTCGTCGCGCTTGGCATGCACTGGGCGGACGCTGTCGCGGGTATTTTTGTGGC
GGTGCTGGTCGGCAAGGCTGCATGGGAGCTGGGCCGGAAAACCATTGACGTCCTGATTGACACCGCTCCCGAGGGACTCT
CCGAACAGATCGAAGAGATCGTCGTGAATGCGCCGGGCGTCATCGGCATCAACAAGATGCGAATCAAACCTGCCGGAGGA
CCGTTCGTCTTTATCGACCTCACCATCTCGGTCAGCCGCACCTTGCCGCAGGAAAAAGTTGTGGCCATCTGCGCCGGAGT
CGAACAGCGGCTGAAGGCAGCGCTTCCCGACAGCGACATCACGGTCAACGCGCGACCGGTGGTGCTCGACAGCGAAACCG
TCACCGAGCGGATTCACACCATCGGCCTGAACCACGGCCTGCACGCGCACAACATACTCACCTCGCTCTCGGGCGACCAC
AAGCAGATCACCTTCGACGTCGAGGTCGACAGTCGCCTGACCATCAGGCAGGCGCACGACGCTGTAACGGAGCTTGAAAA
TGAGCTGCACCGGGAATTCAACGAAGAGATCGACCTCTGCATCCATCTCGATCCGATCAACAGCGAAGAACGCAATGTCC
AGCCTGCCGACCCCGAAAACGAAGCGAGAATCACTGCCCTCATCCGGCAAGCGGCCAGCACGATTCCCGGCATCCTCAAC
GTGCACGCCCTTAAAATCCACGTTTTGAGCTACAACAAACTCTGCATCACGCTGCATTGCGGCTTCGACGACAACACTGT
GCTCGCCGACGTCCACCCGCTCACCAGCCGCCTCGAATGCCTGATCTACCGGGATATTCCCGAAACATCCAGAATCATCG
TCCACGCCGAGCCAGTAAACGCCGGGGATTGA

Upstream 100 bases:

>100_bases
TCGAAATCACCAGAAACGGTGATTGCCATTTTGCAGCAAATCGTTATGTTCGGTCAACTTGCAACATTCACCATCAGCCG
GAATTCCACCCGTTAACCCG

Downstream 100 bases:

>100_bases
GACACGAGCTTGACAACCCCCATGCACACGCCACCAACAATCCTTGCATTCGATGTTTACGGCACGCTGATCGATACGCA
CGGGCTGTGGTGTCGATGCT

Product: cation efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSNHEEKKQHVALSSVAASLLLTAMKLVVGLMTGSIGILSEAAHSAIDFGAAALTWFAVRISDKPADKKHHYGHTKIESV
SALIETGLLILTSVWIIYEAVTRLLSGTTEIEVTWYAIAVIIISIIVDISRASALKKVAKETKSQALEADALHFTSDIVS
SAVVLAGLGFVALGMHWADAVAGIFVAVLVGKAAWELGRKTIDVLIDTAPEGLSEQIEEIVVNAPGVIGINKMRIKPAGG
PFVFIDLTISVSRTLPQEKVVAICAGVEQRLKAALPDSDITVNARPVVLDSETVTERIHTIGLNHGLHAHNILTSLSGDH
KQITFDVEVDSRLTIRQAHDAVTELENELHREFNEEIDLCIHLDPINSEERNVQPADPENEARITALIRQAASTIPGILN
VHALKIHVLSYNKLCITLHCGFDDNTVLADVHPLTSRLECLIYRDIPETSRIIVHAEPVNAGD

Sequences:

>Translated_463_residues
MSNHEEKKQHVALSSVAASLLLTAMKLVVGLMTGSIGILSEAAHSAIDFGAAALTWFAVRISDKPADKKHHYGHTKIESV
SALIETGLLILTSVWIIYEAVTRLLSGTTEIEVTWYAIAVIIISIIVDISRASALKKVAKETKSQALEADALHFTSDIVS
SAVVLAGLGFVALGMHWADAVAGIFVAVLVGKAAWELGRKTIDVLIDTAPEGLSEQIEEIVVNAPGVIGINKMRIKPAGG
PFVFIDLTISVSRTLPQEKVVAICAGVEQRLKAALPDSDITVNARPVVLDSETVTERIHTIGLNHGLHAHNILTSLSGDH
KQITFDVEVDSRLTIRQAHDAVTELENELHREFNEEIDLCIHLDPINSEERNVQPADPENEARITALIRQAASTIPGILN
VHALKIHVLSYNKLCITLHCGFDDNTVLADVHPLTSRLECLIYRDIPETSRIIVHAEPVNAGD
>Mature_462_residues
SNHEEKKQHVALSSVAASLLLTAMKLVVGLMTGSIGILSEAAHSAIDFGAAALTWFAVRISDKPADKKHHYGHTKIESVS
ALIETGLLILTSVWIIYEAVTRLLSGTTEIEVTWYAIAVIIISIIVDISRASALKKVAKETKSQALEADALHFTSDIVSS
AVVLAGLGFVALGMHWADAVAGIFVAVLVGKAAWELGRKTIDVLIDTAPEGLSEQIEEIVVNAPGVIGINKMRIKPAGGP
FVFIDLTISVSRTLPQEKVVAICAGVEQRLKAALPDSDITVNARPVVLDSETVTERIHTIGLNHGLHAHNILTSLSGDHK
QITFDVEVDSRLTIRQAHDAVTELENELHREFNEEIDLCIHLDPINSEERNVQPADPENEARITALIRQAASTIPGILNV
HALKIHVLSYNKLCITLHCGFDDNTVLADVHPLTSRLECLIYRDIPETSRIIVHAEPVNAGD

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=267, Percent_Identity=29.9625468164794, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 50120; Mature: 49989

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHEEKKQHVALSSVAASLLLTAMKLVVGLMTGSIGILSEAAHSAIDFGAAALTWFAVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEE
ISDKPADKKHHYGHTKIESVSALIETGLLILTSVWIIYEAVTRLLSGTTEIEVTWYAIAV
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
IIISIIVDISRASALKKVAKETKSQALEADALHFTSDIVSSAVVLAGLGFVALGMHWADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGIFVAVLVGKAAWELGRKTIDVLIDTAPEGLSEQIEEIVVNAPGVIGINKMRIKPAGG
HHHHHHHHHHHHHHHHHCHHEEEHEEECCCCHHHHHHHHHHHCCCCEEECEEEEEEECCC
PFVFIDLTISVSRTLPQEKVVAICAGVEQRLKAALPDSDITVNARPVVLDSETVTERIHT
CEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEECCHHHHHHHHH
IGLNHGLHAHNILTSLSGDHKQITFDVEVDSRLTIRQAHDAVTELENELHREFNEEIDLC
HCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHCCCEEEE
IHLDPINSEERNVQPADPENEARITALIRQAASTIPGILNVHALKIHVLSYNKLCITLHC
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEEEEECCEEEEEEE
GFDDNTVLADVHPLTSRLECLIYRDIPETSRIIVHAEPVNAGD
CCCCCEEEEECCHHHHHCEEEEEECCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SNHEEKKQHVALSSVAASLLLTAMKLVVGLMTGSIGILSEAAHSAIDFGAAALTWFAVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEE
ISDKPADKKHHYGHTKIESVSALIETGLLILTSVWIIYEAVTRLLSGTTEIEVTWYAIAV
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
IIISIIVDISRASALKKVAKETKSQALEADALHFTSDIVSSAVVLAGLGFVALGMHWADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGIFVAVLVGKAAWELGRKTIDVLIDTAPEGLSEQIEEIVVNAPGVIGINKMRIKPAGG
HHHHHHHHHHHHHHHHHCHHEEEHEEECCCCHHHHHHHHHHHCCCCEEECEEEEEEECCC
PFVFIDLTISVSRTLPQEKVVAICAGVEQRLKAALPDSDITVNARPVVLDSETVTERIHT
CEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEECCHHHHHHHHH
IGLNHGLHAHNILTSLSGDHKQITFDVEVDSRLTIRQAHDAVTELENELHREFNEEIDLC
HCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHCCCEEEE
IHLDPINSEERNVQPADPENEARITALIRQAASTIPGILNVHALKIHVLSYNKLCITLHC
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEEEEECCEEEEEEE
GFDDNTVLADVHPLTSRLECLIYRDIPETSRIIVHAEPVNAGD
CCCCCEEEEECCHHHHHCEEEEEECCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA