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The map label for this gene is atoS [C]

Identifier: 21673366

GI number: 21673366

Start: 538457

End: 540589

Strand: Reverse

Name: atoS [C]

Synonym: CT0531

Alternate gene names: 21673366

Gene position: 540589-538457 (Counterclockwise)

Preceding gene: 21673368

Following gene: 21673363

Centisome position: 25.09

GC content: 48.52

Gene sequence:

>2133_bases
ATGCCTGATCCCAGTATTGATAAGAGAAACGAACAGCAGGCCCCATCACCGCAACCCGATGGTATGCCCGCAGTTGACAC
GCCCCAAGGCAATAATTTTTTCAAGAATATTTTTGAGAACCATGCTGCTGTAATGATGCTTATCGATGCTGAATCAGGCA
GCATCGTCGATGCCAACCAGGCCGCAGCCAGATTTTACGGATGGCCTGTCAGCCAGCTCCGCTCGATGAAAATCGATGAG
ATTAACGCACCATCGTGGGCACATGAACACCCCTGGCTGAAAAAGCTGTCGGAAGAAAAAGAGGACCGATTTTTCTCGAT
GCACCGGAAAGCCGACGGAACACTCTCTTTTGTTGAGCTGAACTTCGGCACAATCCCCCTGGAAAACAAAACGCTGATCC
TGGCCATCATACAGGACAATAGCGAACGCTACAATTTCGCGGCGCTGACCGAATTCAGGCACCATCTTCTCGAAATGGCT
GACAACGCTTCGACCGAGGATTTACTCACCTATACGCTTGATGAGGCTGAACGGCTGACTGGCAGCACACTCGGATTTTT
CGATCTGATCTCGGATGATCAGTCGATTATGAGATCCGCCTGTTCGAGCAACGCAAAAAAAGATAACTGCGGCCATGCAA
GACATCCCATAGTGATCAACTTTAAAGCACCAGCTGACGTCCTACAGAAAAAGAGAGCAATAATCCACAATGATCATGCA
ACACTGAGGCACTGCAACAGCAAATCAGTATCGCACAAGGAAGCCATACGCGAGCTGATCGTACCGGTCATCCGCAACGG
CAAGGTGATGGCAATTCTCGAAGTCGGCAATAAGCCCGCCAACTATGACCAGAATGACATCCAGCTGCTCAACGAGTTGA
GCGGAGTGGCATGGGATATCATTGCCCGAAAGCATGCTGAAGATTCAGCACAAAAGACGATGAAAGCCATGCAGCATACA
CAGAACATGGATTCGATCGGCCGTCTCGCAGGTGGCATTGCCCACGACATCAACAATATGCTTTCGACCATTTTAGGACA
TACTGAAATAGTCATCGAGGAATTGAATGACAAAAGCCCATATGTCGAAAATCTGCTGAACATCCGCGACTCAACCATGC
GCGCAGCCCAACTGATACAGCAATTGCTTGCCTTTGCGCGAAAACAAACGATCCTGCCAAAAATTTTAGAACTGGACACA
GCCCTTCAGGACGAAGTGCCGATGTTGCAAAAACTGATCGGGGAAAAGATACACCTCGAGCTACGCCCCGGTAGTCATGG
AGCAAAAATTCTGATAGACCCATCCCAGTTCGAGCAGTTGCTAACAAGCCTGTGCGCCAATGCGCGCGAAGCCAGCAATG
GCACGGGATCGGTAATTATCGAAACCTCAAGCATAAAAGTGTATCCCGCCGATTGCTATGCAAACCATCCCTGCCAGACT
CCAGGCAATTTTGCCATGATTTCGGTAATTGACAACGGCTGTGGCATAGACAAGAATGTACTTCCCCACATCTTCGAACC
TTTTTTCACCACGAAAGAAGTCGGAAATGGCAGTGGCATGGGACTTTCAACCGTTTATGGTATCGTCACGCAGAACAACG
GCTATCTCGAATGCGAAAGCACTCCAGGCAAGGGAAGCCGCTTTACGATTTACCTGCCCTTGATTGAAGAAACGACCGTG
CCGGACAGAAAGAGGCTGCGGAAAGATACTACCAGTAATGGTGATCAGCTGACAATACTGGTAATCGATGATAATGAGGC
GATCCTTTATATCGTCAAAACCGCTCTTGAAAAAAGGGGATACCGTGTGCTTTCAACAACCTCGGCAAACGAAGCGATCA
ACATCGTGGCAAATTCGGGAAAGAAAATTGACCTGCTTCTGGCTGATGTAGTCATGCCAGAAATGAACGGCAAAGAGCTT
TCAAGGAAACTTCGCGCCATATCCCCTCATCTGAAAACCATTTTTATGTCCGGCTTTCCACAGGAAATAAACTTGTTTGA
CGAGGAGGATACTGAACACGAGAGGTATTTCATCAGCAAACCGTTCAAGCTCGCCGAATTTACCGCCACTATCAAAGCGA
TACTCACTGAGTCTCATGGCACGCAGAACCCCGAAACGGAAACGAAGTCTTGA

Upstream 100 bases:

>100_bases
AGCGCTATACATTTATCAAAAAAAATAGGTATCATTGGAGCATAAATGGTTTTGCATCCGGCGTTATCAATCCCCTTTTT
GCAAAAAAGTATCCCTTGCC

Downstream 100 bases:

>100_bases
TCGAACGTCACCAGCGATAAACGAGGAGAAATGAAAATCCAGTCCATTCACCCAACAAAAAAGGCCCGCTTTCGCAGGCC
TTTTTTGTTGTCATGAACAA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MPDPSIDKRNEQQAPSPQPDGMPAVDTPQGNNFFKNIFENHAAVMMLIDAESGSIVDANQAAARFYGWPVSQLRSMKIDE
INAPSWAHEHPWLKKLSEEKEDRFFSMHRKADGTLSFVELNFGTIPLENKTLILAIIQDNSERYNFAALTEFRHHLLEMA
DNASTEDLLTYTLDEAERLTGSTLGFFDLISDDQSIMRSACSSNAKKDNCGHARHPIVINFKAPADVLQKKRAIIHNDHA
TLRHCNSKSVSHKEAIRELIVPVIRNGKVMAILEVGNKPANYDQNDIQLLNELSGVAWDIIARKHAEDSAQKTMKAMQHT
QNMDSIGRLAGGIAHDINNMLSTILGHTEIVIEELNDKSPYVENLLNIRDSTMRAAQLIQQLLAFARKQTILPKILELDT
ALQDEVPMLQKLIGEKIHLELRPGSHGAKILIDPSQFEQLLTSLCANAREASNGTGSVIIETSSIKVYPADCYANHPCQT
PGNFAMISVIDNGCGIDKNVLPHIFEPFFTTKEVGNGSGMGLSTVYGIVTQNNGYLECESTPGKGSRFTIYLPLIEETTV
PDRKRLRKDTTSNGDQLTILVIDDNEAILYIVKTALEKRGYRVLSTTSANEAINIVANSGKKIDLLLADVVMPEMNGKEL
SRKLRAISPHLKTIFMSGFPQEINLFDEEDTEHERYFISKPFKLAEFTATIKAILTESHGTQNPETETKS

Sequences:

>Translated_710_residues
MPDPSIDKRNEQQAPSPQPDGMPAVDTPQGNNFFKNIFENHAAVMMLIDAESGSIVDANQAAARFYGWPVSQLRSMKIDE
INAPSWAHEHPWLKKLSEEKEDRFFSMHRKADGTLSFVELNFGTIPLENKTLILAIIQDNSERYNFAALTEFRHHLLEMA
DNASTEDLLTYTLDEAERLTGSTLGFFDLISDDQSIMRSACSSNAKKDNCGHARHPIVINFKAPADVLQKKRAIIHNDHA
TLRHCNSKSVSHKEAIRELIVPVIRNGKVMAILEVGNKPANYDQNDIQLLNELSGVAWDIIARKHAEDSAQKTMKAMQHT
QNMDSIGRLAGGIAHDINNMLSTILGHTEIVIEELNDKSPYVENLLNIRDSTMRAAQLIQQLLAFARKQTILPKILELDT
ALQDEVPMLQKLIGEKIHLELRPGSHGAKILIDPSQFEQLLTSLCANAREASNGTGSVIIETSSIKVYPADCYANHPCQT
PGNFAMISVIDNGCGIDKNVLPHIFEPFFTTKEVGNGSGMGLSTVYGIVTQNNGYLECESTPGKGSRFTIYLPLIEETTV
PDRKRLRKDTTSNGDQLTILVIDDNEAILYIVKTALEKRGYRVLSTTSANEAINIVANSGKKIDLLLADVVMPEMNGKEL
SRKLRAISPHLKTIFMSGFPQEINLFDEEDTEHERYFISKPFKLAEFTATIKAILTESHGTQNPETETKS
>Mature_709_residues
PDPSIDKRNEQQAPSPQPDGMPAVDTPQGNNFFKNIFENHAAVMMLIDAESGSIVDANQAAARFYGWPVSQLRSMKIDEI
NAPSWAHEHPWLKKLSEEKEDRFFSMHRKADGTLSFVELNFGTIPLENKTLILAIIQDNSERYNFAALTEFRHHLLEMAD
NASTEDLLTYTLDEAERLTGSTLGFFDLISDDQSIMRSACSSNAKKDNCGHARHPIVINFKAPADVLQKKRAIIHNDHAT
LRHCNSKSVSHKEAIRELIVPVIRNGKVMAILEVGNKPANYDQNDIQLLNELSGVAWDIIARKHAEDSAQKTMKAMQHTQ
NMDSIGRLAGGIAHDINNMLSTILGHTEIVIEELNDKSPYVENLLNIRDSTMRAAQLIQQLLAFARKQTILPKILELDTA
LQDEVPMLQKLIGEKIHLELRPGSHGAKILIDPSQFEQLLTSLCANAREASNGTGSVIIETSSIKVYPADCYANHPCQTP
GNFAMISVIDNGCGIDKNVLPHIFEPFFTTKEVGNGSGMGLSTVYGIVTQNNGYLECESTPGKGSRFTIYLPLIEETTVP
DRKRLRKDTTSNGDQLTILVIDDNEAILYIVKTALEKRGYRVLSTTSANEAINIVANSGKKIDLLLADVVMPEMNGKELS
RKLRAISPHLKTIFMSGFPQEINLFDEEDTEHERYFISKPFKLAEFTATIKAILTESHGTQNPETETKS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=29.6992481203008, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1790436, Length=324, Percent_Identity=25.9259259259259, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=28.7610619469027, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788713, Length=331, Percent_Identity=26.5861027190332, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=506, Percent_Identity=23.3201581027668, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79026; Mature: 78895

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPSIDKRNEQQAPSPQPDGMPAVDTPQGNNFFKNIFENHAAVMMLIDAESGSIVDANQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEECHH
AAARFYGWPVSQLRSMKIDEINAPSWAHEHPWLKKLSEEKEDRFFSMHRKADGTLSFVEL
HHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
NFGTIPLENKTLILAIIQDNSERYNFAALTEFRHHLLEMADNASTEDLLTYTLDEAERLT
ECCEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHC
GSTLGFFDLISDDQSIMRSACSSNAKKDNCGHARHPIVINFKAPADVLQKKRAIIHNDHA
CCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCH
TLRHCNSKSVSHKEAIRELIVPVIRNGKVMAILEVGNKPANYDQNDIQLLNELSGVAWDI
HHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHH
IARKHAEDSAQKTMKAMQHTQNMDSIGRLAGGIAHDINNMLSTILGHTEIVIEELNDKSP
HHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCH
YVENLLNIRDSTMRAAQLIQQLLAFARKQTILPKILELDTALQDEVPMLQKLIGEKIHLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LRPGSHGAKILIDPSQFEQLLTSLCANAREASNGTGSVIIETSSIKVYPADCYANHPCQT
ECCCCCCCEEEECHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCEEEEECCCCCCCCCCC
PGNFAMISVIDNGCGIDKNVLPHIFEPFFTTKEVGNGSGMGLSTVYGIVTQNNGYLECES
CCCEEEEEEEECCCCCCCCCHHHHHHCHHHHHHCCCCCCCCHHHEEEEEECCCCEEEECC
TPGKGSRFTIYLPLIEETTVPDRKRLRKDTTSNGDQLTILVIDDNEAILYIVKTALEKRG
CCCCCCEEEEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCEEEEHHHHHHHHCC
YRVLSTTSANEAINIVANSGKKIDLLLADVVMPEMNGKELSRKLRAISPHLKTIFMSGFP
CEEEEECCCCCEEEEEECCCCEEEEEEEHHHCCCCCHHHHHHHHHHHCHHHHHHHHCCCC
QEINLFDEEDTEHERYFISKPFKLAEFTATIKAILTESHGTQNPETETKS
HHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PDPSIDKRNEQQAPSPQPDGMPAVDTPQGNNFFKNIFENHAAVMMLIDAESGSIVDANQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEECHH
AAARFYGWPVSQLRSMKIDEINAPSWAHEHPWLKKLSEEKEDRFFSMHRKADGTLSFVEL
HHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
NFGTIPLENKTLILAIIQDNSERYNFAALTEFRHHLLEMADNASTEDLLTYTLDEAERLT
ECCEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHC
GSTLGFFDLISDDQSIMRSACSSNAKKDNCGHARHPIVINFKAPADVLQKKRAIIHNDHA
CCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCH
TLRHCNSKSVSHKEAIRELIVPVIRNGKVMAILEVGNKPANYDQNDIQLLNELSGVAWDI
HHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCHHHHH
IARKHAEDSAQKTMKAMQHTQNMDSIGRLAGGIAHDINNMLSTILGHTEIVIEELNDKSP
HHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCH
YVENLLNIRDSTMRAAQLIQQLLAFARKQTILPKILELDTALQDEVPMLQKLIGEKIHLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LRPGSHGAKILIDPSQFEQLLTSLCANAREASNGTGSVIIETSSIKVYPADCYANHPCQT
ECCCCCCCEEEECHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCEEEEECCCCCCCCCCC
PGNFAMISVIDNGCGIDKNVLPHIFEPFFTTKEVGNGSGMGLSTVYGIVTQNNGYLECES
CCCEEEEEEEECCCCCCCCCHHHHHHCHHHHHHCCCCCCCCHHHEEEEEECCCCEEEECC
TPGKGSRFTIYLPLIEETTVPDRKRLRKDTTSNGDQLTILVIDDNEAILYIVKTALEKRG
CCCCCCEEEEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCEEEEHHHHHHHHCC
YRVLSTTSANEAINIVANSGKKIDLLLADVVMPEMNGKELSRKLRAISPHLKTIFMSGFP
CEEEEECCCCCEEEEEECCCCEEEEEEEHHHCCCCCHHHHHHHHHHHCHHHHHHHHCCCC
QEINLFDEEDTEHERYFISKPFKLAEFTATIKAILTESHGTQNPETETKS
HHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA