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The map label for this gene is acoC [H]

Identifier: 21673359

GI number: 21673359

Start: 531345

End: 532214

Strand: Reverse

Name: acoC [H]

Synonym: CT0524

Alternate gene names: 21673359

Gene position: 532214-531345 (Counterclockwise)

Preceding gene: 21673363

Following gene: 21673357

Centisome position: 24.7

GC content: 59.31

Gene sequence:

>870_bases
ATGAAAACTCAATCGCAAGATCGCTGGTTTATCTGGCAGCTCTCCGAAGAGCTTGAAGCGAAAATCCGCTATCGGGAGTA
CGGCCCGCCTGATTCCCCCTTTACACCACTGCTTTTCATCCATGGCTACGGCGGCATGATCGAGCACTGGAACGACAACA
TCCCCTCTTTCGACGACCGGTACAGAATCTACGCCATGGACCTGATCGGCTTCGGCCAGTCCGGCAAGCCAAACGTGCGC
TACAGCCTGGCGCTCTTCGCGGCGCAAATCAAGGCGTTCATGCATCTGAAAAAGCTTGAAAAGGTCACGCTGGTAGGTCA
CTCGATGGGCGCGGCCAGCAGCATCATCTACGCGCATCACAATCCGGACAGCGTCCGGGCGCTCGTGCTGGCCAATCCCT
CCGGCCTGTACGGCGACAGCATGGACGGCGTCGCCAAGATCTTTTTCGGTCTGGTCGGTTCGCCCCTGATCGGCGAAATG
CTCTTCGCAGCTTTCGCCAATCCCGTCGGCGTCAGCCAGAGCCTTACCCCCACCTACTACAACCAGAAAAAGGTTGATCT
GAACCTGATCAACCAGTTCTCACGCCCGTTGCAGGATCGCGGGGCGATCTTCTCCTACCTCTCTCCCTCCAAACGCCCGC
ACGACTTCATGCTCGACGGCCTCAAGCCCTGCAACTACAAGGGCGACGCGTGGCTGCTCTGGGGCGCGGAGGACACCGCC
CTGCCGCCGCACAAGATCATTCCGGAGTTTCAGGAGCTGCTCCCCCAGGCTGGTGCATACATCATCCCGAAAGCCGGCCA
CTGCATCCATCACGATGCGCACGAGACCTTCAACAACCGCCTCGCGCAGCTTCTCCAGCGGCTGGAGTAA

Upstream 100 bases:

>100_bases
AGGAAATTCCCGATCTACCTTTATTCTTTCGGGCTGCCGATATATTTTATGAAATAATATCCACCAACAGCCATTGTCCG
GCCATGTCCTGATACGACGC

Downstream 100 bases:

>100_bases
CAACAGAGTTCTGTAGCTGATACTGCCCCAGCCTACTCCGGAGACTGAACAATATGGCCGCTTCCCGCCTTCAGCTTCAG
GTACTTGAGGTTGGCCGGTT

Product: dihydrolipoamide acetyltransferase, putative

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKTQSQDRWFIWQLSEELEAKIRYREYGPPDSPFTPLLFIHGYGGMIEHWNDNIPSFDDRYRIYAMDLIGFGQSGKPNVR
YSLALFAAQIKAFMHLKKLEKVTLVGHSMGAASSIIYAHHNPDSVRALVLANPSGLYGDSMDGVAKIFFGLVGSPLIGEM
LFAAFANPVGVSQSLTPTYYNQKKVDLNLINQFSRPLQDRGAIFSYLSPSKRPHDFMLDGLKPCNYKGDAWLLWGAEDTA
LPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNNRLAQLLQRLE

Sequences:

>Translated_289_residues
MKTQSQDRWFIWQLSEELEAKIRYREYGPPDSPFTPLLFIHGYGGMIEHWNDNIPSFDDRYRIYAMDLIGFGQSGKPNVR
YSLALFAAQIKAFMHLKKLEKVTLVGHSMGAASSIIYAHHNPDSVRALVLANPSGLYGDSMDGVAKIFFGLVGSPLIGEM
LFAAFANPVGVSQSLTPTYYNQKKVDLNLINQFSRPLQDRGAIFSYLSPSKRPHDFMLDGLKPCNYKGDAWLLWGAEDTA
LPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNNRLAQLLQRLE
>Mature_289_residues
MKTQSQDRWFIWQLSEELEAKIRYREYGPPDSPFTPLLFIHGYGGMIEHWNDNIPSFDDRYRIYAMDLIGFGQSGKPNVR
YSLALFAAQIKAFMHLKKLEKVTLVGHSMGAASSIIYAHHNPDSVRALVLANPSGLYGDSMDGVAKIFFGLVGSPLIGEM
LFAAFANPVGVSQSLTPTYYNQKKVDLNLINQFSRPLQDRGAIFSYLSPSKRPHDFMLDGLKPCNYKGDAWLLWGAEDTA
LPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNNRLAQLLQRLE

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=122, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24586385, Length=140, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24586387, Length=140, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24586391, Length=140, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24586389, Length=140, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 32578; Mature: 32578

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQSQDRWFIWQLSEELEAKIRYREYGPPDSPFTPLLFIHGYGGMIEHWNDNIPSFDDR
CCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCC
YRIYAMDLIGFGQSGKPNVRYSLALFAAQIKAFMHLKKLEKVTLVGHSMGAASSIIYAHH
EEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEC
NPDSVRALVLANPSGLYGDSMDGVAKIFFGLVGSPLIGEMLFAAFANPVGVSQSLTPTYY
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NQKKVDLNLINQFSRPLQDRGAIFSYLSPSKRPHDFMLDGLKPCNYKGDAWLLWGAEDTA
CCCCCHHHHHHHHHCCHHHCCCEEHHCCCCCCCCHHHHCCCCCCCCCCCEEEEECCCCCC
LPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNNRLAQLLQRLE
CCCHHHHHHHHHHHHHCCCEEECCCCCEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTQSQDRWFIWQLSEELEAKIRYREYGPPDSPFTPLLFIHGYGGMIEHWNDNIPSFDDR
CCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCC
YRIYAMDLIGFGQSGKPNVRYSLALFAAQIKAFMHLKKLEKVTLVGHSMGAASSIIYAHH
EEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEC
NPDSVRALVLANPSGLYGDSMDGVAKIFFGLVGSPLIGEMLFAAFANPVGVSQSLTPTYY
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NQKKVDLNLINQFSRPLQDRGAIFSYLSPSKRPHDFMLDGLKPCNYKGDAWLLWGAEDTA
CCCCCHHHHHHHHHCCHHHCCCEEHHCCCCCCCCHHHHCCCCCCCCCCCEEEEECCCCCC
LPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNNRLAQLLQRLE
CCCHHHHHHHHHHHHHCCCEEECCCCCEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]