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The map label for this gene is nrfD [H]

Identifier: 21673329

GI number: 21673329

Start: 506234

End: 507154

Strand: Reverse

Name: nrfD [H]

Synonym: CT0494

Alternate gene names: 21673329

Gene position: 507154-506234 (Counterclockwise)

Preceding gene: 21673330

Following gene: 21673328

Centisome position: 23.53

GC content: 59.61

Gene sequence:

>921_bases
ATGACCTTTGTACATCAGGAAGTATGGCACTGGCAGATCGCAACCTACCTGTTTCTGGGCGGTCTGGGCGGCGCGACGTT
CGCCATCAGCGCGGTGCTTCACCTCTTCGAGGGGTGCGACCGCAAAATGCTTTCCGTGGCCGTCATGTCGTCGATAGCGT
TTCTGGTCATCGGCACTGTGTTCCTGCTCGCCGACATGCTTCAGCCGCTGAAAGCAATCTATGCCCTGACCAATCCGCGC
TCGTGGATTTTCTGGGGTGTGGTCTTCATCAACGCCTACTTCGTCGCAGCCATCGCCTATGTGATTCCGCTGCTCGAAGA
GTGGCCGATGCTACAGCCAATCATACAGAAAATCCCCGCGCCGATCCTCGGCCTGCTCGAACGCTTCAACAAGCTGGTCG
CCCTCGGCGGCTCGGCAGCCGGATTCCTCGTGGCGATCTACACCGGCCTGTTGATCTCGGCCGCTCCAGCGATCAACTTC
TGGAACACCCCGGCATTGCCGCTGCTCTTCGTGATCTCCGGCTTCTCGACCGGCGCGGCCTGGCTGCTCCTGCTCTCGAT
GCTCTCCAGCAACCCCGGCGCACAGGCTATCAGCGCCAAGCTCGAACAGCTCGACGCCATACTGATCGTCACAGAACTTA
TTATTCTCGGTGCATACTTCAACTTCGCCATGTTCCTGCCCACCAGCGCGCGCGCCTCGGCGGAGTTCCTGTTCCACAGC
CCGGTCTTCATCGTCGGCTTCTTCGTGGCTGGTCTTTTGGTGCCGCTCGCCATTGAAAGCTGGGGCATCTTCTTCGGCGG
CCATTCGGAGAAGGACAAACCGAAGCTGACGATGCTGCTCGCCAGCGCTCTGGTGCTTGTCGGCGGCTACCTCCTGCGTA
TCTACGTACTCAAAGCCGGCATGTTCCAGTACCCCTGGTAA

Upstream 100 bases:

>100_bases
GCACAAGCTCGCCGCGAGCGGCAAGGCGCAGGCGCTCAACCAGGGCCTCGGCACCTCGCCGAAAGTATTCTACATCCCAT
CATAAAGGAGGGCACTCATT

Downstream 100 bases:

>100_bases
GCGAGCCAGAACCGACAACCCCGACGCCCGGCCTTCAAACGGATCACCGGGCGTCCATCGTTCGACCAATCATGACGCCG
CTCCAGAAAGCCTACCGCTA

Product: polysulfide reductase, subunit C, putative

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIAFLVIGTVFLLADMLQPLKAIYALTNPR
SWIFWGVVFINAYFVAAIAYVIPLLEEWPMLQPIIQKIPAPILGLLERFNKLVALGGSAAGFLVAIYTGLLISAAPAINF
WNTPALPLLFVISGFSTGAAWLLLLSMLSSNPGAQAISAKLEQLDAILIVTELIILGAYFNFAMFLPTSARASAEFLFHS
PVFIVGFFVAGLLVPLAIESWGIFFGGHSEKDKPKLTMLLASALVLVGGYLLRIYVLKAGMFQYPW

Sequences:

>Translated_306_residues
MTFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIAFLVIGTVFLLADMLQPLKAIYALTNPR
SWIFWGVVFINAYFVAAIAYVIPLLEEWPMLQPIIQKIPAPILGLLERFNKLVALGGSAAGFLVAIYTGLLISAAPAINF
WNTPALPLLFVISGFSTGAAWLLLLSMLSSNPGAQAISAKLEQLDAILIVTELIILGAYFNFAMFLPTSARASAEFLFHS
PVFIVGFFVAGLLVPLAIESWGIFFGGHSEKDKPKLTMLLASALVLVGGYLLRIYVLKAGMFQYPW
>Mature_305_residues
TFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIAFLVIGTVFLLADMLQPLKAIYALTNPRS
WIFWGVVFINAYFVAAIAYVIPLLEEWPMLQPIIQKIPAPILGLLERFNKLVALGGSAAGFLVAIYTGLLISAAPAINFW
NTPALPLLFVISGFSTGAAWLLLLSMLSSNPGAQAISAKLEQLDAILIVTELIILGAYFNFAMFLPTSARASAEFLFHSP
VFIVGFFVAGLLVPLAIESWGIFFGGHSEKDKPKLTMLLASALVLVGGYLLRIYVLKAGMFQYPW

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG3301

COG function: function code P; Formate-dependent nitrite reductase, membrane component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI1790509, Length=324, Percent_Identity=25.6172839506173, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017566
- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 33380; Mature: 33249

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00318 HMG_COA_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIAFLVIGTV
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FLLADMLQPLKAIYALTNPRSWIFWGVVFINAYFVAAIAYVIPLLEEWPMLQPIIQKIPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCH
PILGLLERFNKLVALGGSAAGFLVAIYTGLLISAAPAINFWNTPALPLLFVISGFSTGAA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHH
WLLLLSMLSSNPGAQAISAKLEQLDAILIVTELIILGAYFNFAMFLPTSARASAEFLFHS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
PVFIVGFFVAGLLVPLAIESWGIFFGGHSEKDKPKLTMLLASALVLVGGYLLRIYVLKAG
HHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
MFQYPW
CCCCCC
>Mature Secondary Structure 
TFVHQEVWHWQIATYLFLGGLGGATFAISAVLHLFEGCDRKMLSVAVMSSIAFLVIGTV
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FLLADMLQPLKAIYALTNPRSWIFWGVVFINAYFVAAIAYVIPLLEEWPMLQPIIQKIPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCH
PILGLLERFNKLVALGGSAAGFLVAIYTGLLISAAPAINFWNTPALPLLFVISGFSTGAA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHH
WLLLLSMLSSNPGAQAISAKLEQLDAILIVTELIILGAYFNFAMFLPTSARASAEFLFHS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
PVFIVGFFVAGLLVPLAIESWGIFFGGHSEKDKPKLTMLLASALVLVGGYLLRIYVLKAG
HHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
MFQYPW
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8057835; 8265357; 9278503 [H]