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The map label for this gene is clpX [H]

Identifier: 21673243

GI number: 21673243

Start: 420167

End: 421486

Strand: Direct

Name: clpX [H]

Synonym: CT0404

Alternate gene names: 21673243

Gene position: 420167-421486 (Clockwise)

Preceding gene: 21673242

Following gene: 21673245

Centisome position: 19.5

GC content: 57.05

Gene sequence:

>1320_bases
ATGATAAAAGACAAAGAGCCGCGTAAAGGCCAGAACGGCGGAAGGAAAAGTTACGGATCGGAACCGCCGGTTGTTTGCTC
CTTCTGCGGAAGAACAAGCCAGGAGGTAAACAGCATGGTCGCTGGGCCGAGAGCCTTCATCTGCGACCGCTGCATTCTCA
GCTCGGTAGAGATTTTGCGCAAGGAGATCAGCGCCATCCGTCATCCGGATCAGTCGCCTGAACCCGCTTTCCAGCCACGG
CTGAAAAGCCCCGTCAACATCAAGGAGGCGCTTGACCAGTACGTCATCGGTCAGGAGCAGGCCAAGAAGTCGCTCGCCGT
GGCGGTCTATAACCACTACAAGCGACTTGACGCCCACGACTGGTCGTCCGGCGACGAGGTGGTGATCGAAAAGAGCAACA
TCCTGCTCATTGGTCCGACCGGCACCGGCAAGACGCTGCTCGCCCAAACGCTGGCCAACCTGCTCGAAGTGCCCTTCACC
ATTGCTGATGCCACTTCGCTCACCGAAGCGGGCTACGTGGGCGACGACGTCGAGACCATTCTTGCACGGCTTCTGCACGC
CTCCGACTTCAACCTCGAACGCGCCGAGCGCGGCATCATCTACGTCGATGAAATCGACAAGATTGCCCGCAAATCGGCCA
ACGTTTCAATCACGAGAGATGTTTCTGGCGAAGGCGTTCAGCAGGCGTTGCTCAAGATTCTTGAAGGCTCAGTGGTTGGC
GTGCCACCGAAAGGCGGACGCAAGCATCCGGAGCAGCAGTTGATCAACATCAACACCAAGAACATCCTCTTCATCTGTGG
AGGAGCGTTCGAAGGACTCGACAAGATCATCGCTCGCCGTGTCTCGAAATCCTCGATGGGCTTCGGCTCCAAGGTCAGAG
GCAAACAGACAGGCTACGATCCGGAGATTCTCAAGCTTGTCACACAGGACGACCTGCATGACTACGGCCTTATCCCCGAA
TTTATCGGAAGACTACCCGTCATGTCCGTCCTCGAACCGCTCGATGCCGTCGCCCTGCGCAACATCCTTGTCGAGCCAAA
AAACGCGCTCGTCAAGCAGTACAAGCGGTTGTTCGAAATGGACGGCGTGGAACTTGAATTCACCGACGAAGCGCTCGAGC
GCGTGGTTGCAATCGCCATCGAACGCGGCACCGGTGCGCGCGCCCTGCGCTCCGTGCTCGAAAACGTCATGATCGACATT
ATGTTCGAGTTGCCCACCCGCAAGGATGTGCAGAAGTGCGTCATCACCGCCGAAACCATCGACAAAACCGGCGGGCCGGT
GTATGAAAAGAAGGATGGAAAAGAGCGCAAGATCGCATAA

Upstream 100 bases:

>100_bases
CTTTCATTCAGCCAGGATCGAAAAATTTCAGGGCATCAGTCAAATAATTTCAATAGCGTGAACGTGTCGGCAATAACCGC
GCAATCACAACCGCTACCAA

Downstream 100 bases:

>100_bases
AAAGAGTTTGGATTCAGCCGGAAAAGTCCTATATTAGGGCCTTCTCGAAGGGGCGGTTAGCTCAGTTGGTTAGAGCGCTA
CCTTGACACGGTAGAGGTCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MIKDKEPRKGQNGGRKSYGSEPPVVCSFCGRTSQEVNSMVAGPRAFICDRCILSSVEILRKEISAIRHPDQSPEPAFQPR
LKSPVNIKEALDQYVIGQEQAKKSLAVAVYNHYKRLDAHDWSSGDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFT
IADATSLTEAGYVGDDVETILARLLHASDFNLERAERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVG
VPPKGGRKHPEQQLININTKNILFICGGAFEGLDKIIARRVSKSSMGFGSKVRGKQTGYDPEILKLVTQDDLHDYGLIPE
FIGRLPVMSVLEPLDAVALRNILVEPKNALVKQYKRLFEMDGVELEFTDEALERVVAIAIERGTGARALRSVLENVMIDI
MFELPTRKDVQKCVITAETIDKTGGPVYEKKDGKERKIA

Sequences:

>Translated_439_residues
MIKDKEPRKGQNGGRKSYGSEPPVVCSFCGRTSQEVNSMVAGPRAFICDRCILSSVEILRKEISAIRHPDQSPEPAFQPR
LKSPVNIKEALDQYVIGQEQAKKSLAVAVYNHYKRLDAHDWSSGDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFT
IADATSLTEAGYVGDDVETILARLLHASDFNLERAERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVG
VPPKGGRKHPEQQLININTKNILFICGGAFEGLDKIIARRVSKSSMGFGSKVRGKQTGYDPEILKLVTQDDLHDYGLIPE
FIGRLPVMSVLEPLDAVALRNILVEPKNALVKQYKRLFEMDGVELEFTDEALERVVAIAIERGTGARALRSVLENVMIDI
MFELPTRKDVQKCVITAETIDKTGGPVYEKKDGKERKIA
>Mature_439_residues
MIKDKEPRKGQNGGRKSYGSEPPVVCSFCGRTSQEVNSMVAGPRAFICDRCILSSVEILRKEISAIRHPDQSPEPAFQPR
LKSPVNIKEALDQYVIGQEQAKKSLAVAVYNHYKRLDAHDWSSGDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFT
IADATSLTEAGYVGDDVETILARLLHASDFNLERAERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVG
VPPKGGRKHPEQQLININTKNILFICGGAFEGLDKIIARRVSKSSMGFGSKVRGKQTGYDPEILKLVTQDDLHDYGLIPE
FIGRLPVMSVLEPLDAVALRNILVEPKNALVKQYKRLFEMDGVELEFTDEALERVVAIAIERGTGARALRSVLENVMIDI
MFELPTRKDVQKCVITAETIDKTGGPVYEKKDGKERKIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=337, Percent_Identity=45.9940652818991, Blast_Score=287, Evalue=2e-77,
Organism=Escherichia coli, GI1786642, Length=426, Percent_Identity=54.6948356807512, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=31.924882629108, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=375, Percent_Identity=39.2, Blast_Score=264, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=375, Percent_Identity=39.2, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=418, Percent_Identity=37.799043062201, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=40, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=431, Percent_Identity=37.3549883990719, Blast_Score=256, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=43.75, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=43.75, Blast_Score=282, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 48332; Mature: 48332

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDKEPRKGQNGGRKSYGSEPPVVCSFCGRTSQEVNSMVAGPRAFICDRCILSSVEILR
CCCCCCCCCCCCCCCCCCCCCCCEEEHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KEISAIRHPDQSPEPAFQPRLKSPVNIKEALDQYVIGQEQAKKSLAVAVYNHYKRLDAHD
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
WSSGDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFTIADATSLTEAGYVGDDVETI
CCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHCCCCCCCHHHH
LARLLHASDFNLERAERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVG
HHHHHHCCCCCHHHHHCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEE
VPPKGGRKHPEQQLININTKNILFICGGAFEGLDKIIARRVSKSSMGFGSKVRGKQTGYD
CCCCCCCCCCHHHEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEILKLVTQDDLHDYGLIPEFIGRLPVMSVLEPLDAVALRNILVEPKNALVKQYKRLFEM
HHHHHHHHHCCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
DGVELEFTDEALERVVAIAIERGTGARALRSVLENVMIDIMFELPTRKDVQKCVITAETI
CCCEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DKTGGPVYEKKDGKERKIA
HCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKDKEPRKGQNGGRKSYGSEPPVVCSFCGRTSQEVNSMVAGPRAFICDRCILSSVEILR
CCCCCCCCCCCCCCCCCCCCCCCEEEHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KEISAIRHPDQSPEPAFQPRLKSPVNIKEALDQYVIGQEQAKKSLAVAVYNHYKRLDAHD
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
WSSGDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFTIADATSLTEAGYVGDDVETI
CCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHCCCCCCCHHHH
LARLLHASDFNLERAERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGSVVG
HHHHHHCCCCCHHHHHCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEE
VPPKGGRKHPEQQLININTKNILFICGGAFEGLDKIIARRVSKSSMGFGSKVRGKQTGYD
CCCCCCCCCCHHHEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEILKLVTQDDLHDYGLIPEFIGRLPVMSVLEPLDAVALRNILVEPKNALVKQYKRLFEM
HHHHHHHHHCCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
DGVELEFTDEALERVVAIAIERGTGARALRSVLENVMIDIMFELPTRKDVQKCVITAETI
CCCEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DKTGGPVYEKKDGKERKIA
HCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA