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The map label for this gene is tadA [H]

Identifier: 21673220

GI number: 21673220

Start: 394138

End: 394596

Strand: Direct

Name: tadA [H]

Synonym: CT0381

Alternate gene names: 21673220

Gene position: 394138-394596 (Clockwise)

Preceding gene: 21673217

Following gene: 21673222

Centisome position: 18.29

GC content: 61.44

Gene sequence:

>459_bases
ATGTCTGACCTGAACCACTGCATGGAACTCGCCTTCAGGGAGGCGATCAAGGCGTACGAAAGCAAGGAGGTGCCGGTCGG
CGCGGTGGTGCTCGACCCGAACGGCTTGATCATCGGGCGCGGCTACAACCAGGTGGAGACTCTGTCGGACGCCACCGCGC
ACGCCGAAATGATCGCCCTGACCTCGGCAATGGCAACTATAGGCAGCAAATATCTCGAAGGATGCACGCTCGCCGTTACG
CTCGAACCCTGCCCAATGTGCGCAGGGGCGATCGTGCTGTCGAAAATCAGCCGCGTGGTCTTTGGCGCGTGGGATCCCAA
GATGGGCGCGGCGGGAACCGTTCTCAACATTACCGCCTGCAACGCACTCAACCACCAGCCCGAGGTGTATGGCGGCATCA
TGGAGCGCAAAGCCGAAAGTTTGTTGCAGGATTTCTTCCGGGGGCTGCGGGGGCGGTGA

Upstream 100 bases:

>100_bases
ACCGGGCTTAACGCGGAAAAAAGTTTAAACTTTATGATAACAAAAATTCTTGTTTTACTGAAACCGCTGTGGCTCGTAGC
GCACATTTCTTCGCATCATG

Downstream 100 bases:

>100_bases
AGAAGAAAGAAGAGAAACAAGAGGCTGAGGAGGTTTCGTTTGGACTCCTGCTGAGTCAATAACCGACGATCTCCCGATTG
AAGAGTTCCATGATCACCGT

Product: cytosine deaminase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MSDLNHCMELAFREAIKAYESKEVPVGAVVLDPNGLIIGRGYNQVETLSDATAHAEMIALTSAMATIGSKYLEGCTLAVT
LEPCPMCAGAIVLSKISRVVFGAWDPKMGAAGTVLNITACNALNHQPEVYGGIMERKAESLLQDFFRGLRGR

Sequences:

>Translated_152_residues
MSDLNHCMELAFREAIKAYESKEVPVGAVVLDPNGLIIGRGYNQVETLSDATAHAEMIALTSAMATIGSKYLEGCTLAVT
LEPCPMCAGAIVLSKISRVVFGAWDPKMGAAGTVLNITACNALNHQPEVYGGIMERKAESLLQDFFRGLRGR
>Mature_151_residues
SDLNHCMELAFREAIKAYESKEVPVGAVVLDPNGLIIGRGYNQVETLSDATAHAEMIALTSAMATIGSKYLEGCTLAVTL
EPCPMCAGAIVLSKISRVVFGAWDPKMGAAGTVLNITACNALNHQPEVYGGIMERKAESLLQDFFRGLRGR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=148, Percent_Identity=35.8108108108108, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=42.8571428571429, Blast_Score=120, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17541138, Length=145, Percent_Identity=35.1724137931034, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=39.1752577319588, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555996, Length=79, Percent_Identity=39.2405063291139, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=158, Percent_Identity=32.2784810126582, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=96, Percent_Identity=36.4583333333333, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=32.6530612244898, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16262; Mature: 16131

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50096 IQ ; PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLNHCMELAFREAIKAYESKEVPVGAVVLDPNGLIIGRGYNQVETLSDATAHAEMIAL
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
TSAMATIGSKYLEGCTLAVTLEPCPMCAGAIVLSKISRVVFGAWDPKMGAAGTVLNITAC
HHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
NALNHQPEVYGGIMERKAESLLQDFFRGLRGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDLNHCMELAFREAIKAYESKEVPVGAVVLDPNGLIIGRGYNQVETLSDATAHAEMIAL
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
TSAMATIGSKYLEGCTLAVTLEPCPMCAGAIVLSKISRVVFGAWDPKMGAAGTVLNITAC
HHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
NALNHQPEVYGGIMERKAESLLQDFFRGLRGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]