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The map label for this gene is sucC [H]

Identifier: 21673219

GI number: 21673219

Start: 392817

End: 393995

Strand: Reverse

Name: sucC [H]

Synonym: CT0380

Alternate gene names: 21673219

Gene position: 393995-392817 (Counterclockwise)

Preceding gene: 21673221

Following gene: 21673218

Centisome position: 18.28

GC content: 58.52

Gene sequence:

>1179_bases
ATGAATATTCATGAGTATCAGGGTAAAGGCATCCTGAAACAGTTCGGCGTGGCCGTTCCCAAGGGCATAGTAGCATTTTC
GGCTGAAGAAGCAAAACAAGCGGCAGAGCAGCTCTTCGAGGAGCAGTCGAGCCCCGTAGTGGTCGTCAAGGCGCAGATTC
ACGCCGGTGGCCGCGGCAAGGCTGGCGGTGTCAAACTGGCAAAATCGCCTGAAGAGGTGTTCGAAATCGCCCAGAAAATG
CTCGGCGCAACGCTGGTAACACACCAGACCGGACCCGAAGGCAAGGAGGTTCGCCGTCTCCTCATCGAAGAGGGCATGAA
TATCGACAAGGAGTTCTACCTCGGCATCACCCTCGACCGCACCACGTCGAGCAACGTGCTCATGGTCTCGACCGAAGGCG
GCATGGAGATCGAGAAAGTGGCCGAAGAGACCCCAGAAAAGCTGCTCAAGATTCACGTCGATCCAGTCTACGGCCTGCAG
GGCTTCCAGGCTCGCAAGGCGGCGTTCTTCCTCGGCTTGCAGGGTGAGCAGTTCCGCAACGGCGTCAAGTTCATCGAGGC
GCTTTACAACGCGTACACCACCATCGACGCCTCGCTGGCTGAGATCAACCCGCTGGTCATCACCAAGGAGGGCCGCGTGC
TCGCGCTCGACGCCAAGATCAACTTCGACGACAACGCCCTCTACCGCCACTCTGATTTCCACGATCTGCGTGACATTACC
GAAGAGGATCCGCTCGAATACGAAGCCTCGAAATCGAACCTCAACTACGTGCGCCTCGACGGCAACGTTGGCTGCATGGT
CAACGGCGCAGGCCTGGCGATGGGCACCATGGACCTCATCCAGCTCTCCGGCGGCAGACCGGCCAACTTCCTTGATGTCG
GCGGCGGTGCAAGCTCCAAGACAGTCGAAGAGGGTTTCAAAATCATCTTGGGCGACAAAAACGTCAAGGCGATCCTGGTC
AACATCTTCGGCGGCATCGTACGCTGCGACCGCGTGGCCGGAGGCATCATCGAAGCCGCCAAAAACATCGGCCTGAAGGT
ACCGGTGATCGTGCGCCTCGAAGGCACAAACGCCACAGAGGCCCAGAAAATGCTCGACGAATCGGGTCTCAACCTCATCT
CGGCCAAAGGCCTGAGGGACGCTGCGGAAAAGGTGCAGAAGGCACTGGCCACAGCATAA

Upstream 100 bases:

>100_bases
GTAAAACAAGAATTTTTGTTATCATAAAGTTTAAACTTTTTTCCGCGTTAAGCCCGGTACCGACCGGCAAGTATTCTCCC
GTAACCATAGAACTTGTACT

Downstream 100 bases:

>100_bases
AGTCCCAACACACGCAAACAAACGGAAAAGCCCGCCCCCACAGAACGAACTTCATGGAGGCGGGCTTTTCCGTTTTGCCA
CTAACACAGGAGAAAAAAAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAEQLFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVFEIAQKM
LGATLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRTTSSNVLMVSTEGGMEIEKVAEETPEKLLKIHVDPVYGLQ
GFQARKAAFFLGLQGEQFRNGVKFIEALYNAYTTIDASLAEINPLVITKEGRVLALDAKINFDDNALYRHSDFHDLRDIT
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLSGGRPANFLDVGGGASSKTVEEGFKIILGDKNVKAILV
NIFGGIVRCDRVAGGIIEAAKNIGLKVPVIVRLEGTNATEAQKMLDESGLNLISAKGLRDAAEKVQKALATA

Sequences:

>Translated_392_residues
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAEQLFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVFEIAQKM
LGATLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRTTSSNVLMVSTEGGMEIEKVAEETPEKLLKIHVDPVYGLQ
GFQARKAAFFLGLQGEQFRNGVKFIEALYNAYTTIDASLAEINPLVITKEGRVLALDAKINFDDNALYRHSDFHDLRDIT
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLSGGRPANFLDVGGGASSKTVEEGFKIILGDKNVKAILV
NIFGGIVRCDRVAGGIIEAAKNIGLKVPVIVRLEGTNATEAQKMLDESGLNLISAKGLRDAAEKVQKALATA
>Mature_392_residues
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAEQLFEEQSSPVVVVKAQIHAGGRGKAGGVKLAKSPEEVFEIAQKM
LGATLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDRTTSSNVLMVSTEGGMEIEKVAEETPEKLLKIHVDPVYGLQ
GFQARKAAFFLGLQGEQFRNGVKFIEALYNAYTTIDASLAEINPLVITKEGRVLALDAKINFDDNALYRHSDFHDLRDIT
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLSGGRPANFLDVGGGASSKTVEEGFKIILGDKNVKAILV
NIFGGIVRCDRVAGGIIEAAKNIGLKVPVIVRLEGTNATEAQKMLDESGLNLISAKGLRDAAEKVQKALATA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=45.6852791878173, Blast_Score=341, Evalue=6e-94,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=46.2532299741602, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=45.7300275482094, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786948, Length=389, Percent_Identity=52.1850899742931, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=43.21608040201, Blast_Score=327, Evalue=9e-90,
Organism=Caenorhabditis elegans, GI17567829, Length=393, Percent_Identity=43.2569974554707, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=42.5316455696203, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=45.2261306532663, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=43.3333333333333, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=43.3333333333333, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=43.4782608695652, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=43.4782608695652, Blast_Score=312, Evalue=2e-85,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42218; Mature: 42218

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAEQLFEEQSSPVVVVKAQIHAGGRGK
CCCCCCCCCCHHHHHCCCCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
AGGVKLAKSPEEVFEIAQKMLGATLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDR
CCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEC
TTSSNVLMVSTEGGMEIEKVAEETPEKLLKIHVDPVYGLQGFQARKAAFFLGLQGEQFRN
CCCCCEEEEECCCCCHHHHHHHHCHHHHEEEECCCCCCCCCCCCCCEEEEEECCCHHHHH
GVKFIEALYNAYTTIDASLAEINPLVITKEGRVLALDAKINFDDNALYRHSDFHDLRDIT
HHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCEEEEEEEECCCCCCEEECCCHHHHHHCC
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLSGGRPANFLDVGGGASSK
CCCCCCEECCCCCCCEEEECCCEEEEEECCCCCCCCEEHEEECCCCCCCEEECCCCCCCH
TVEEGFKIILGDKNVKAILVNIFGGIVRCDRVAGGIIEAAKNIGLKVPVIVRLEGTNATE
HHHCCCEEEECCCCHHEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
AQKMLDESGLNLISAKGLRDAAEKVQKALATA
HHHHHHHCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQGKGILKQFGVAVPKGIVAFSAEEAKQAAEQLFEEQSSPVVVVKAQIHAGGRGK
CCCCCCCCCCHHHHHCCCCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
AGGVKLAKSPEEVFEIAQKMLGATLVTHQTGPEGKEVRRLLIEEGMNIDKEFYLGITLDR
CCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEC
TTSSNVLMVSTEGGMEIEKVAEETPEKLLKIHVDPVYGLQGFQARKAAFFLGLQGEQFRN
CCCCCEEEEECCCCCHHHHHHHHCHHHHEEEECCCCCCCCCCCCCCEEEEEECCCHHHHH
GVKFIEALYNAYTTIDASLAEINPLVITKEGRVLALDAKINFDDNALYRHSDFHDLRDIT
HHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCEEEEEEEECCCCCCEEECCCHHHHHHCC
EEDPLEYEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDLIQLSGGRPANFLDVGGGASSK
CCCCCCEECCCCCCCEEEECCCEEEEEECCCCCCCCEEHEEECCCCCCCEEECCCCCCCH
TVEEGFKIILGDKNVKAILVNIFGGIVRCDRVAGGIIEAAKNIGLKVPVIVRLEGTNATE
HHHCCCEEEECCCCHHEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
AQKMLDESGLNLISAKGLRDAAEKVQKALATA
HHHHHHHCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA