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The map label for this gene is fbp [H]

Identifier: 21673197

GI number: 21673197

Start: 371232

End: 372233

Strand: Reverse

Name: fbp [H]

Synonym: CT0358

Alternate gene names: 21673197

Gene position: 372233-371232 (Counterclockwise)

Preceding gene: 21673200

Following gene: 21673195

Centisome position: 17.27

GC content: 59.28

Gene sequence:

>1002_bases
ATGAACAAGCTCACCACCATTGAAAGCCATTTCCTGCAATTGCAGAAACGCTATCCCGAAATCAACAGCGAAGTGACCGA
CCTCCTCAACGACGTCGCCTTCGCGGCCAAGCTGGTGCGGCGCGAAGTCGTGCGGGCGGGTCTGGCCGACATTCTCGGCC
TTGCCGGATCGACCAACGTGCAGGGCGAAGAGGTCAAGAAGCTCGACCTGTTCGCCAACGAGCGGCTCATCAACGCCATC
GGTCAGCACGGGCGCTTCGCCATCATGGGTTCCGAGGAGAACGAAGAGATCATCAAGCCGCCCAAGTTCGAGTCGGGCGA
ATACGTCCTGCTCTTCGACCCGCTCGATGGCTCGTCGAACATCGACGTGAACGTCAGCGTCGGCACCATTTTCTCGATCT
ACCGGCTCAAGAGCGGCGAGCCATCGCAGGCCAGCCTCGAGGACTGCCTGCAGAAAGGGGCTGACCAGATTGCCGCCGGA
TACGTCATCTACGGCTCGTCGGTGATGATGGTTTATACCACGGGCCACGGCGTTCACGGTTTCACCTACGACCAGACCGT
CGGCGAGTTCCTGCTCTCGCACGAGAACATCACCACTCCCGAACACGGTAAATACTACTCGGTCAACGAGGGCTCCTGGC
AGGAGTTCAACGACGGCACGAAGCGCTTTCTCGACTACCTCAAGGAAGAAGACAAAGCAACCGGACGCCCCTACAGCACC
CGCTACATCGGTTCGTTCGTCGCCGATTTCCACCGCAACCTGCTCACCGGCGGAGTGTTCGTCTATCCGGCCACAAAGAA
GCACAAAAACGGCAAGCTGCGCCTGATGTACGAAGCCAACCCGATGGCCTTCATCTGCGAACAGGCTGGAGGCCGCGCCA
CCGACGGATACCGCCGGATTCTCGACATAGAGCCTAAGGAGCTGCACCAGCGCACGCCGCTCTACATCGGCAGCAAAAAC
GACGTCCTCATCGCCGAAGAGTTCGAACAAGGGAAGCGATGA

Upstream 100 bases:

>100_bases
GCCGCTTCCCGGCGCCACAGCGACAAGGCCGCCCTTGCATTCAGTGCCGCGAAAGCCCCGGCTGAACCGGCCTCCCAATA
ACCTTCTGAACGATTTTGTG

Downstream 100 bases:

>100_bases
TTTTTATTCAACTTTGCTGACAACAAAAACCCCAACTAAATGGCTGGGGTTTTTGTTTTTCAATCTCGATAATCAGGGCA
ACCTCATTCTGACTTGATTA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNKLTTIESHFLQLQKRYPEINSEVTDLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAI
GQHGRFAIMGSEENEEIIKPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSGEPSQASLEDCLQKGADQIAAG
YVIYGSSVMMVYTTGHGVHGFTYDQTVGEFLLSHENITTPEHGKYYSVNEGSWQEFNDGTKRFLDYLKEEDKATGRPYST
RYIGSFVADFHRNLLTGGVFVYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGYRRILDIEPKELHQRTPLYIGSKN
DVLIAEEFEQGKR

Sequences:

>Translated_333_residues
MNKLTTIESHFLQLQKRYPEINSEVTDLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAI
GQHGRFAIMGSEENEEIIKPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSGEPSQASLEDCLQKGADQIAAG
YVIYGSSVMMVYTTGHGVHGFTYDQTVGEFLLSHENITTPEHGKYYSVNEGSWQEFNDGTKRFLDYLKEEDKATGRPYST
RYIGSFVADFHRNLLTGGVFVYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGYRRILDIEPKELHQRTPLYIGSKN
DVLIAEEFEQGKR
>Mature_333_residues
MNKLTTIESHFLQLQKRYPEINSEVTDLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAI
GQHGRFAIMGSEENEEIIKPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSGEPSQASLEDCLQKGADQIAAG
YVIYGSSVMMVYTTGHGVHGFTYDQTVGEFLLSHENITTPEHGKYYSVNEGSWQEFNDGTKRFLDYLKEEDKATGRPYST
RYIGSFVADFHRNLLTGGVFVYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGYRRILDIEPKELHQRTPLYIGSKN
DVLIAEEFEQGKR

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=318, Percent_Identity=45.2830188679245, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI16579888, Length=318, Percent_Identity=45.2830188679245, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI22907028, Length=315, Percent_Identity=45.0793650793651, Blast_Score=271, Evalue=8e-73,
Organism=Escherichia coli, GI1790679, Length=325, Percent_Identity=52.6153846153846, Blast_Score=353, Evalue=7e-99,
Organism=Caenorhabditis elegans, GI17508131, Length=325, Percent_Identity=47.3846153846154, Blast_Score=312, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6323409, Length=321, Percent_Identity=42.3676012461059, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI45550998, Length=317, Percent_Identity=47.9495268138801, Blast_Score=299, Evalue=1e-81,
Organism=Drosophila melanogaster, GI19921562, Length=317, Percent_Identity=47.9495268138801, Blast_Score=299, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37312; Mature: 37312

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTTIESHFLQLQKRYPEINSEVTDLLNDVAFAAKLVRREVVRAGLADILGLAGSTNV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGEEVKKLDLFANERLINAIGQHGRFAIMGSEENEEIIKPPKFESGEYVLLFDPLDGSSN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
IDVNVSVGTIFSIYRLKSGEPSQASLEDCLQKGADQIAAGYVIYGSSVMMVYTTGHGVHG
EEEEEEHHHEEEEEEECCCCCCHHHHHHHHHHCHHHHHCCEEEECCCEEEEEEECCCCCC
FTYDQTVGEFLLSHENITTPEHGKYYSVNEGSWQEFNDGTKRFLDYLKEEDKATGRPYST
CCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHCHHHHHHHHHHHHHHHCCCCCCCH
RYIGSFVADFHRNLLTGGVFVYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGYRRI
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCHHHE
LDIEPKELHQRTPLYIGSKNDVLIAEEFEQGKR
ECCCHHHHHCCCCEEECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MNKLTTIESHFLQLQKRYPEINSEVTDLLNDVAFAAKLVRREVVRAGLADILGLAGSTNV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGEEVKKLDLFANERLINAIGQHGRFAIMGSEENEEIIKPPKFESGEYVLLFDPLDGSSN
CHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
IDVNVSVGTIFSIYRLKSGEPSQASLEDCLQKGADQIAAGYVIYGSSVMMVYTTGHGVHG
EEEEEEHHHEEEEEEECCCCCCHHHHHHHHHHCHHHHHCCEEEECCCEEEEEEECCCCCC
FTYDQTVGEFLLSHENITTPEHGKYYSVNEGSWQEFNDGTKRFLDYLKEEDKATGRPYST
CCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHCHHHHHHHHHHHHHHHCCCCCCCH
RYIGSFVADFHRNLLTGGVFVYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGYRRI
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCHHHE
LDIEPKELHQRTPLYIGSKNDVLIAEEFEQGKR
ECCCHHHHHCCCCEEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA