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The map label for this gene is aat

Identifier: 21673185

GI number: 21673185

Start: 362325

End: 362909

Strand: Direct

Name: aat

Synonym: CT0346

Alternate gene names: 21673185

Gene position: 362325-362909 (Clockwise)

Preceding gene: 21673184

Following gene: 21673186

Centisome position: 16.81

GC content: 56.07

Gene sequence:

>585_bases
ATGATAAAAGTAGAGGATATTCTGCGTGCCTACAGGCACGGCTTTTTCCCGATGGCCGACTCTCGCGAGGGGACGGTGAG
CTGGTGCCAGCCCTACCAGCGCGCGGTGGTGCCGCTCGACAGTTTCCGGCCGTCGCGAAGCCTCCGGCGCGTCATTGGCA
AAAAGCGTTTTACCATCAAAATCAATTCAGTTTTCGAACAGGTGATCCGTGCCTGCTCGCAGCCTCGTTCAACCGGGCAG
GAGACCTGGCTTTCGGAGGAGATTATCAAGGTGTTTCTCAAGCTGCATCGTCTCGGAGTGGCGCACAGTGTGGAGAGCTG
GCAGGATGGCGAGCTTGCCGGAGGGCTGTACGGTCTGTCGATGGGTGGGGCTTTTTTCGGTGAGTCGATGTTCTTTTTTC
GGTCTGATGCCTCGAAAGTCGCCTTTGCCTGGCTGGTGGGCTATCTCAAACGCAAAGGCTATCTCCTGCTCGACGCGCAG
ATCATGAACCCACACCTTGAGAGTCTCGGTGCGATTGAAATCCCCCACGAAGAGTACATGGTGCAGCTTGAGCGCGCTCT
CGGAAAAAAGATTTCGTTTGTCTGA

Upstream 100 bases:

>100_bases
CTGGCGCGACAAACATGGTATTCACCATGTGCCGAAGCGGCAGGTCGATGAATTGCTGGTGACGGCGGAACAGCTTCGTG
AACGCGGGTAAGTCCTTAGC

Downstream 100 bases:

>100_bases
GAAGCAAAGGGGAAAAGAGCTACCTTTTTCTATTTGACAACGGGTTGAAACGCGGCCTTTATTCAACGTTCGATCAACCG
CTGTTTTCGAAGCACCAATT

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIKVEDILRAYRHGFFPMADSREGTVSWCQPYQRAVVPLDSFRPSRSLRRVIGKKRFTIKINSVFEQVIRACSQPRSTGQ
ETWLSEEIIKVFLKLHRLGVAHSVESWQDGELAGGLYGLSMGGAFFGESMFFFRSDASKVAFAWLVGYLKRKGYLLLDAQ
IMNPHLESLGAIEIPHEEYMVQLERALGKKISFV

Sequences:

>Translated_194_residues
MIKVEDILRAYRHGFFPMADSREGTVSWCQPYQRAVVPLDSFRPSRSLRRVIGKKRFTIKINSVFEQVIRACSQPRSTGQ
ETWLSEEIIKVFLKLHRLGVAHSVESWQDGELAGGLYGLSMGGAFFGESMFFFRSDASKVAFAWLVGYLKRKGYLLLDAQ
IMNPHLESLGAIEIPHEEYMVQLERALGKKISFV
>Mature_194_residues
MIKVEDILRAYRHGFFPMADSREGTVSWCQPYQRAVVPLDSFRPSRSLRRVIGKKRFTIKINSVFEQVIRACSQPRSTGQ
ETWLSEEIIKVFLKLHRLGVAHSVESWQDGELAGGLYGLSMGGAFFGESMFFFRSDASKVAFAWLVGYLKRKGYLLLDAQ
IMNPHLESLGAIEIPHEEYMVQLERALGKKISFV

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=179, Percent_Identity=37.4301675977654, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_CHLTE (Q8KFI0)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661250.1
- ProteinModelPortal:   Q8KFI0
- SMR:   Q8KFI0
- GeneID:   1008008
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0346
- NMPDR:   fig|194439.1.peg.344
- TIGR:   CT0346
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- ProtClustDB:   PRK00301
- BioCyc:   CTEP194439:CT_0346-MONOMER
- BRENDA:   2.3.2.6
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 22136; Mature: 22136

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVEDILRAYRHGFFPMADSREGTVSWCQPYQRAVVPLDSFRPSRSLRRVIGKKRFTIK
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCEEEEE
INSVFEQVIRACSQPRSTGQETWLSEEIIKVFLKLHRLGVAHSVESWQDGELAGGLYGLS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
MGGAFFGESMFFFRSDASKVAFAWLVGYLKRKGYLLLDAQIMNPHLESLGAIEIPHEEYM
HCHHHHHCCHHEEECCCHHHHHHHHHHHHHHCCEEEEEHHHHCHHHHHCCCEECCHHHHH
VQLERALGKKISFV
HHHHHHHHHHCCCC
>Mature Secondary Structure
MIKVEDILRAYRHGFFPMADSREGTVSWCQPYQRAVVPLDSFRPSRSLRRVIGKKRFTIK
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCEEEEE
INSVFEQVIRACSQPRSTGQETWLSEEIIKVFLKLHRLGVAHSVESWQDGELAGGLYGLS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
MGGAFFGESMFFFRSDASKVAFAWLVGYLKRKGYLLLDAQIMNPHLESLGAIEIPHEEYM
HCHHHHHCCHHEEECCCHHHHHHHHHHHHHHCCEEEEEHHHHCHHHHHCCCEECCHHHHH
VQLERALGKKISFV
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901