Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 21673174

GI number: 21673174

Start: 351961

End: 352557

Strand: Direct

Name: pgsA [H]

Synonym: CT0335

Alternate gene names: 21673174

Gene position: 351961-352557 (Clockwise)

Preceding gene: 21673173

Following gene: 21673175

Centisome position: 16.33

GC content: 54.44

Gene sequence:

>597_bases
ATGACTTTTTCCAATCAGCTTACCATTCTGAGAATCATTCTCGTGCCGGTTTTCGTGCTGCTGCTCATGCAGGATAGCGC
GTGGTACAGGCTGTTGGGGGTCATTGTCTTCGTAACGGCTTCTCTCACCGATATTTACGATGGCTACCACGCCCGTAAGT
ACGGCGAGGTGACGCGGCTCGGAGCGTTTCTTGATCCGCTGGCCGACAAGTTGCTCATCACTACGGCATTTCTTTTCTAT
GTATGGGAAGGCTATCTGGCGCTCTGGATGGTGTTGCTCGTGGCTGCCCGTGACATCGTGGTGACGGGGCTGCGCGTCTA
TGCGGAGCACATCGACCATCCTGTGGTGACCAGCAAGGAGGCCAAGTACAAAACCTTCGCGCAGAACCTGTTCGCCTATG
TTATCATGCTTTTCATCCTGCTGAAGGAGAAGAGCTTTTTCGGCCCGAAGATGGCGGCTTTCATGGAGGTGATTCTCCAT
TCGCCCTGGCTTGGTTACGCGATGTTCGCCATTACGCTGTTTACGGTCTGGACTGGGGTTTCCTACCTCATCAGCAACAG
GCGCCTCATCTTCCGGAATTCTGCGGGAGGGCGCTGA

Upstream 100 bases:

>100_bases
CGTATTTCAGTCAGCTTTGACAAAATGTGCAGGATGAAGTATCTTTTGCCCTTGCGAACGTTCGGATTGAGGAGGCATCG
ACTTCAATTTCATCATCAAC

Downstream 100 bases:

>100_bases
AGCCATGCGGCAATGGCTCGGCAGAATCTTCGGGAGCGCCTTTGGTATTGGGTATGTGCCGTTTGCGCCGGGCACCTTCG
CCAGCGGAGCCGCCGCGCTG

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTFSNQLTILRIILVPVFVLLLMQDSAWYRLLGVIVFVTASLTDIYDGYHARKYGEVTRLGAFLDPLADKLLITTAFLFY
VWEGYLALWMVLLVAARDIVVTGLRVYAEHIDHPVVTSKEAKYKTFAQNLFAYVIMLFILLKEKSFFGPKMAAFMEVILH
SPWLGYAMFAITLFTVWTGVSYLISNRRLIFRNSAGGR

Sequences:

>Translated_198_residues
MTFSNQLTILRIILVPVFVLLLMQDSAWYRLLGVIVFVTASLTDIYDGYHARKYGEVTRLGAFLDPLADKLLITTAFLFY
VWEGYLALWMVLLVAARDIVVTGLRVYAEHIDHPVVTSKEAKYKTFAQNLFAYVIMLFILLKEKSFFGPKMAAFMEVILH
SPWLGYAMFAITLFTVWTGVSYLISNRRLIFRNSAGGR
>Mature_197_residues
TFSNQLTILRIILVPVFVLLLMQDSAWYRLLGVIVFVTASLTDIYDGYHARKYGEVTRLGAFLDPLADKLLITTAFLFYV
WEGYLALWMVLLVAARDIVVTGLRVYAEHIDHPVVTSKEAKYKTFAQNLFAYVIMLFILLKEKSFFGPKMAAFMEVILHS
PWLGYAMFAITLFTVWTGVSYLISNRRLIFRNSAGGR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=127, Percent_Identity=37.7952755905512, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22667; Mature: 22536

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSNQLTILRIILVPVFVLLLMQDSAWYRLLGVIVFVTASLTDIYDGYHARKYGEVTRL
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GAFLDPLADKLLITTAFLFYVWEGYLALWMVLLVAARDIVVTGLRVYAEHIDHPVVTSKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AKYKTFAQNLFAYVIMLFILLKEKSFFGPKMAAFMEVILHSPWLGYAMFAITLFTVWTGV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SYLISNRRLIFRNSAGGR
HHHHHCCEEEEECCCCCC
>Mature Secondary Structure 
TFSNQLTILRIILVPVFVLLLMQDSAWYRLLGVIVFVTASLTDIYDGYHARKYGEVTRL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GAFLDPLADKLLITTAFLFYVWEGYLALWMVLLVAARDIVVTGLRVYAEHIDHPVVTSKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AKYKTFAQNLFAYVIMLFILLKEKSFFGPKMAAFMEVILHSPWLGYAMFAITLFTVWTGV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SYLISNRRLIFRNSAGGR
HHHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA