Click here to switch to the map view.

The map label for this gene is ileS

Identifier: 21673150

GI number: 21673150

Start: 324937

End: 328191

Strand: Direct

Name: ileS

Synonym: CT0311

Alternate gene names: 21673150

Gene position: 324937-328191 (Clockwise)

Preceding gene: 21673149

Following gene: 21673151

Centisome position: 15.08

GC content: 59.51

Gene sequence:

>3255_bases
ATGCCAGCCACCTATCCCGAGTACCCGTCCAGCCTTTCCTACAGCGCCATGGAGGCGCAAATCCGCGAGTTCTGGATCGA
ACGGAATATTTTCAGGAAGAGCCTCGAAAAGGATGCGCCCAAAGGCATCTACTCCTTTTACGAAGGCCCGCCGACGGTGA
ATGGAAAGCCCGGCGTGCACCACCTGTTCAGCCGCACCATCAAGGATGTGGTGTGCCGTTACCACACCATGCAGGGCTAT
CAGGTTCCGCGCAAGGCTGGCTGGGACACGCACGGCCTGCCGGTCGAAATCTCGGTCGAGAAGAAGCTTGGCCTAAAAAA
CAAGTCGCACGTCGAGGAGTACGGCGTGGGCGAGTTCAACCGTGAGGCGCGAGCGCTGGTTTATCACCACATCGACGACA
ACCGCGAGGGGTGGGGCAAGCTGACTGAGCGCATGGGCTATTGGGTCGATATGGACAGCCCTTACATCACCTGCGACAAT
AATTATATCGAGTCGGTTTGGTGGGCCCTGAAGACCATTTTCGACAAAGGGCTGATCTACAAGGATTACAAGATCGTGCC
GCAGGATCCGAAGTCCGAGACCGTGCTCAGCTCGCACGAGCTGGCGCTGGGCTACAAAGAGGTGCAGGATCCGAGTGTCT
ATATCAAGTTTCGCCTGAAGGATTCGGGTGAAAGCATTCTCGTCTGGACGACCACGCCGTGGACGCTCATCTCGAACGTC
GCCCTCGCCGTTGGCCGCGACATCGACTACGTGCGCGTCAAGCATCGCGAAACTGGCGAGGTGCTGATTCTGGCCGAGTC
GCGCTTGTCGGTGCTTGTCGAGAAGATCGGCGACGAGTCGGCCTGGGAAGTCATCGACCGCTGCAAAGGCAGTGATCTCG
AAGGGCGCGACTACGAGCCGCTTTTCAACTACTTTTCGCCGGAGCGCCGCGCATGGTACGTGGTGTGTGGCGATTTCGTT
TCGACCGGCGAAGGTACCGGCATTGTGCACATCGCTCCGGCGTTCGGCGCGGACGACTACGAGCTGTCGAAGCAGTACCA
GCTTCCGATGCTTCAGCCGGTGGCTCGCAACGGCTGCTTCACCGCCGAGGTTCCGGACTACGAGGGGATGTTCTTCAAGG
ATGCCGACAAGCCGATCATGCAGCGGCTCAAGGAGGAGGGCAAGCTCTACCGCCGCGAGACGATCCAGCACACCTACCCC
TTCTCGTGGCGTTACGATGTGCCGGTGATCTACTACGCCCGCGAGTCGTGGTACATCCGCACTACCGACATCGCACCGCG
CATGGTGGCGCTGAACAAGACGATCAACTGGAACCCGCCGGAGATTGGCACGGGCCGCTTCGGCAACTGGCTCGAAGAGA
ACAAAGACTGGGCGCTTTCCCGCGAACGCTTTTGGGGCACGCCGCTGCCGGTTTGGGTTGCCGAGGATTTCGCCATCGGC
GATGGCCCCGACTCCGGCAAGCTCTTCGCGGTCGGCTCGGTCGCGGAGCTTCGCGAGGGCTTCATCGAGATTGATGGCGA
AGAGATGAATCTCGGCGATGCGCTTGACAAGGGGCTCGTCGAACTCGACCTGCACAAGCCGTTCGTGGATCGCATCTGGT
TCATCCGCGATGGCAAGCGCTTCAACCGCACGCCGGAGCTGATCGACGTCTGGTTCGATAGCGGCTCGATGCCCTTCGCC
CAGCTGCACTACCCATTCGAGAACAAAGAGCTGTTCGACAAGACCTTCCCGGCGGACTTTATCGCCGAGGGCGTTGACCA
GACGCGAGGCTGGTTTTACACGCTGCACGCCATCGCAACGCTCATTTTCGACCGTCCGGCCTACCGGAACGTCGTTGTCA
ACGGTCACATCCTCGACAAGAGTGGCCAGAAGATGTCCAAATCGAAAGGCAATGTGGTCGATCCGTTCGAGTCGATGGAG
CAGTACGGCGCGGACGCTATCCGCTGGTATCTGATGATCACCAGCCCGCCGTGGCGCCCGAAGCTTTTCAATGCCGCCGA
GATCGAGGAGGAGCAGCGCAAGTTCTTCCGCGCCTTCATCAACAGCTACAACTTTTTCGTGCTCTACGCGAACGTCGATG
GCTTTCGCTACGAAGAGGCTGACATTCCGTTCACTCAGCGTTCGGAGCTTGACCGCTGGGTCCTCTCCAGCCTCAACACG
CTCATCGCCGAAGTGACCAGCCGCATGGAGCAGTATGACCTCACGGGTGCGTGCCGTCTCATTGGCGACTTCACCGTTGA
TGATCTGTCGAACTGGTACATCCGCCGCTCGCGCAAACGCTTCTGGAAGGGGGAGATGGGGCCGGACAAGCTTTCGGCCT
ACCAGACGCTCTCGACGGTGCTCGAAACGCTCGCGAAGCTGATGGCTCCGTTCGTACCTTTCATCGCCGAAAAAATCTGG
CTCGACCTGAAGAGCGTCGGTGGAACCTCGAAAGCCGAATCGGTGCACTTGGCCGACTGGCCGGTGGCCGATGAAAGCTG
CATCGATGCGGCGCTCGAAGAGCGCATGAAGAAGGCGCAGATCATCACCTCGCTGGTGCGCACCATGCGCGAGAAGGCCG
GCATCAAGGTGCGCCAGCCGCTCCGGCGCATCCTGCTCGCCGCCGCCGAACCCGGTTCGCGCGCCGCCTATGAGCTGGTA
TCGGACATCATCAAGGAAGAGGTCAATGTCCAGAAGATCGAGTATGTCGAGGACGAGGATGGCTCGGTTATCAGCAAGAA
GGCCAAGCCCAATTTCAAGACCCTCGGTCCACGTTTCGGCAAGGACATGAAGCTGCTGGCCGAGGAGATCAGGATCATGA
GTCACAAGCAGATTTCGCGCCTTGAAAAGGAAGGTTCCATCGAGATCGATCTCGGCGGACGCATCTGCACCGTGCTTCGT
GAGGATGTTGACATCGTGCACGAGGACATCGAGGGGTGGCTGGTGGCGGCGGACGACGCGCACCGCATCATGGTGGCGCT
TGACACCGAAATCACCGAAGAGCTTGAGATGCTTGGTCTGGCCCGCGAGCTGGTCAGCCGCATCCAGACGCTCCGCAAGG
AGAGTGGTCTCGAAATTACCGACCGTATCGCTCTGACGATTGCGGGCAGCGAAAAGCTGCTGGCGGCGGCCAGAAAGAGC
GAGTCCTATATTATGGACGAAACGCTTGCCACGTCGATTGTACTGTTGCCGCTCGACGATTCGCAGCCGGGCGACGGCGT
GGAGCAGGTCAACAATGAATTGTGCCGGTTGTCGCTTGAAAAATCCGGTTCGTGA

Upstream 100 bases:

>100_bases
CTCTTTTCCTGCCGATTCTCGTATATTCAGACTTTTCCGCGAAAACGGGCCATAACCTGCTTTTCGCTTACGATATTTCC
AGTTTGACATTTTCCAAGCC

Downstream 100 bases:

>100_bases
TCGTATTATATAACTTCGTGTTTTTTTACGGTTTACCGCTGGGTTGCCGTTGGAACCTCTAAACCATGACCATCATGTCG
AAGAAAACCAGCCCTGTTCA

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1084; Mature: 1083

Protein sequence:

>1084_residues
MPATYPEYPSSLSYSAMEAQIREFWIERNIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVHHLFSRTIKDVVCRYHTMQGY
QVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFNREARALVYHHIDDNREGWGKLTERMGYWVDMDSPYITCDN
NYIESVWWALKTIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYIKFRLKDSGESILVWTTTPWTLISNV
ALAVGRDIDYVRVKHRETGEVLILAESRLSVLVEKIGDESAWEVIDRCKGSDLEGRDYEPLFNYFSPERRAWYVVCGDFV
STGEGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCFTAEVPDYEGMFFKDADKPIMQRLKEEGKLYRRETIQHTYP
FSWRYDVPVIYYARESWYIRTTDIAPRMVALNKTINWNPPEIGTGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIG
DGPDSGKLFAVGSVAELREGFIEIDGEEMNLGDALDKGLVELDLHKPFVDRIWFIRDGKRFNRTPELIDVWFDSGSMPFA
QLHYPFENKELFDKTFPADFIAEGVDQTRGWFYTLHAIATLIFDRPAYRNVVVNGHILDKSGQKMSKSKGNVVDPFESME
QYGADAIRWYLMITSPPWRPKLFNAAEIEEEQRKFFRAFINSYNFFVLYANVDGFRYEEADIPFTQRSELDRWVLSSLNT
LIAEVTSRMEQYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTVLETLAKLMAPFVPFIAEKIW
LDLKSVGGTSKAESVHLADWPVADESCIDAALEERMKKAQIITSLVRTMREKAGIKVRQPLRRILLAAAEPGSRAAYELV
SDIIKEEVNVQKIEYVEDEDGSVISKKAKPNFKTLGPRFGKDMKLLAEEIRIMSHKQISRLEKEGSIEIDLGGRICTVLR
EDVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSRIQTLRKESGLEITDRIALTIAGSEKLLAAARKS
ESYIMDETLATSIVLLPLDDSQPGDGVEQVNNELCRLSLEKSGS

Sequences:

>Translated_1084_residues
MPATYPEYPSSLSYSAMEAQIREFWIERNIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVHHLFSRTIKDVVCRYHTMQGY
QVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFNREARALVYHHIDDNREGWGKLTERMGYWVDMDSPYITCDN
NYIESVWWALKTIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYIKFRLKDSGESILVWTTTPWTLISNV
ALAVGRDIDYVRVKHRETGEVLILAESRLSVLVEKIGDESAWEVIDRCKGSDLEGRDYEPLFNYFSPERRAWYVVCGDFV
STGEGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCFTAEVPDYEGMFFKDADKPIMQRLKEEGKLYRRETIQHTYP
FSWRYDVPVIYYARESWYIRTTDIAPRMVALNKTINWNPPEIGTGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIG
DGPDSGKLFAVGSVAELREGFIEIDGEEMNLGDALDKGLVELDLHKPFVDRIWFIRDGKRFNRTPELIDVWFDSGSMPFA
QLHYPFENKELFDKTFPADFIAEGVDQTRGWFYTLHAIATLIFDRPAYRNVVVNGHILDKSGQKMSKSKGNVVDPFESME
QYGADAIRWYLMITSPPWRPKLFNAAEIEEEQRKFFRAFINSYNFFVLYANVDGFRYEEADIPFTQRSELDRWVLSSLNT
LIAEVTSRMEQYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTVLETLAKLMAPFVPFIAEKIW
LDLKSVGGTSKAESVHLADWPVADESCIDAALEERMKKAQIITSLVRTMREKAGIKVRQPLRRILLAAAEPGSRAAYELV
SDIIKEEVNVQKIEYVEDEDGSVISKKAKPNFKTLGPRFGKDMKLLAEEIRIMSHKQISRLEKEGSIEIDLGGRICTVLR
EDVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSRIQTLRKESGLEITDRIALTIAGSEKLLAAARKS
ESYIMDETLATSIVLLPLDDSQPGDGVEQVNNELCRLSLEKSGS
>Mature_1083_residues
PATYPEYPSSLSYSAMEAQIREFWIERNIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVHHLFSRTIKDVVCRYHTMQGYQ
VPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFNREARALVYHHIDDNREGWGKLTERMGYWVDMDSPYITCDNN
YIESVWWALKTIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYIKFRLKDSGESILVWTTTPWTLISNVA
LAVGRDIDYVRVKHRETGEVLILAESRLSVLVEKIGDESAWEVIDRCKGSDLEGRDYEPLFNYFSPERRAWYVVCGDFVS
TGEGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCFTAEVPDYEGMFFKDADKPIMQRLKEEGKLYRRETIQHTYPF
SWRYDVPVIYYARESWYIRTTDIAPRMVALNKTINWNPPEIGTGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIGD
GPDSGKLFAVGSVAELREGFIEIDGEEMNLGDALDKGLVELDLHKPFVDRIWFIRDGKRFNRTPELIDVWFDSGSMPFAQ
LHYPFENKELFDKTFPADFIAEGVDQTRGWFYTLHAIATLIFDRPAYRNVVVNGHILDKSGQKMSKSKGNVVDPFESMEQ
YGADAIRWYLMITSPPWRPKLFNAAEIEEEQRKFFRAFINSYNFFVLYANVDGFRYEEADIPFTQRSELDRWVLSSLNTL
IAEVTSRMEQYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTVLETLAKLMAPFVPFIAEKIWL
DLKSVGGTSKAESVHLADWPVADESCIDAALEERMKKAQIITSLVRTMREKAGIKVRQPLRRILLAAAEPGSRAAYELVS
DIIKEEVNVQKIEYVEDEDGSVISKKAKPNFKTLGPRFGKDMKLLAEEIRIMSHKQISRLEKEGSIEIDLGGRICTVLRE
DVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSRIQTLRKESGLEITDRIALTIAGSEKLLAAARKSE
SYIMDETLATSIVLLPLDDSQPGDGVEQVNNELCRLSLEKSGS

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1050, Percent_Identity=37.8095238095238, Blast_Score=702, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1050, Percent_Identity=37.8095238095238, Blast_Score=702, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=942, Percent_Identity=27.6008492569002, Blast_Score=308, Evalue=2e-83,
Organism=Homo sapiens, GI268370293, Length=929, Percent_Identity=23.6813778256189, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI268370297, Length=929, Percent_Identity=23.6813778256189, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI268370295, Length=885, Percent_Identity=23.954802259887, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI5454158, Length=865, Percent_Identity=22.4277456647399, Blast_Score=164, Evalue=4e-40,
Organism=Escherichia coli, GI2367096, Length=816, Percent_Identity=27.0833333333333, Blast_Score=305, Evalue=9e-84,
Organism=Escherichia coli, GI1790708, Length=940, Percent_Identity=24.1489361702128, Blast_Score=190, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17541896, Length=1050, Percent_Identity=37.4285714285714, Blast_Score=680, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=803, Percent_Identity=26.027397260274, Blast_Score=238, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17510661, Length=927, Percent_Identity=22.2222222222222, Blast_Score=176, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI72001587, Length=928, Percent_Identity=22.7370689655172, Blast_Score=146, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1112, Percent_Identity=35.341726618705, Blast_Score=646, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=845, Percent_Identity=24.4970414201183, Blast_Score=231, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6321531, Length=875, Percent_Identity=22.5142857142857, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28574730, Length=1083, Percent_Identity=35.3647276084949, Blast_Score=642, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1083, Percent_Identity=35.3647276084949, Blast_Score=642, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1083, Percent_Identity=35.3647276084949, Blast_Score=642, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=841, Percent_Identity=27.2294887039239, Blast_Score=265, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17864482, Length=909, Percent_Identity=22.7722772277228, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653289, Length=909, Percent_Identity=22.7722772277228, Blast_Score=175, Evalue=2e-43,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_CHLTE (Q8KFL5)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661215.1
- ProteinModelPortal:   Q8KFL5
- SMR:   Q8KFL5
- GeneID:   1007971
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0311
- NMPDR:   fig|194439.1.peg.309
- TIGR:   CT0311
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BioCyc:   CTEP194439:CT_0311-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 124098; Mature: 123967

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 627-627

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATYPEYPSSLSYSAMEAQIREFWIERNIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHH
HLFSRTIKDVVCRYHTMQGYQVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFN
HHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCEEEEEHHHCCCCCHHHHHHCCCCCCC
REARALVYHHIDDNREGWGKLTERMGYWVDMDSPYITCDNNYIESVWWALKTIFDKGLIY
CCCEEEEEEECCCCCCHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEE
KDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYIKFRLKDSGESILVWTTTPWTLISNV
ECCEECCCCCCCCCHHCCCHHHCCHHHCCCCEEEEEEEEECCCCEEEEEECCCHHHHHHH
ALAVGRDIDYVRVKHRETGEVLILAESRLSVLVEKIGDESAWEVIDRCKGSDLEGRDYEP
HHHHCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCH
LFNYFSPERRAWYVVCGDFVSTGEGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCF
HHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHCCCCE
TAEVPDYEGMFFKDADKPIMQRLKEEGKLYRRETIQHTYPFSWRYDVPVIYYARESWYIR
EECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCEEEE
TTDIAPRMVALNKTINWNPPEIGTGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIG
ECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEECHHHHCCCCCCEEEECCEECC
DGPDSGKLFAVGSVAELREGFIEIDGEEMNLGDALDKGLVELDLHKPFVDRIWFIRDGKR
CCCCCCCEEEECCHHHHHCCCEEECCCCCCCHHHHHCCCEEEECCCCHHHHEEEEECCCC
FNRTPELIDVWFDSGSMPFAQLHYPFENKELFDKTFPADFIAEGVDQTRGWFYTLHAIAT
CCCCCCEEEEEECCCCCCHHEEECCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
LIFDRPAYRNVVVNGHILDKSGQKMSKSKGNVVDPFESMEQYGADAIRWYLMITSPPWRP
HHHCCCCCCEEEEEEEEECCCCCHHHHCCCCCCCHHHHHHHHCCCEEEEEEEEECCCCCC
KLFNAAEIEEEQRKFFRAFINSYNFFVLYANVDGFRYEEADIPFTQRSELDRWVLSSLNT
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHH
LIAEVTSRMEQYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTV
HHHHHHHHHHHHCCCHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LETLAKLMAPFVPFIAEKIWLDLKSVGGTSKAESVHLADWPVADESCIDAALEERMKKAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
IITSLVRTMREKAGIKVRQPLRRILLAAAEPGSRAAYELVSDIIKEEVNVQKIEYVEDED
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
GSVISKKAKPNFKTLGPRFGKDMKLLAEEIRIMSHKQISRLEKEGSIEIDLGGRICTVLR
CCEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHH
EDVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSRIQTLRKESGLEIT
HHHHHHHHCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DRIALTIAGSEKLLAAARKSESYIMDETLATSIVLLPLDDSQPGDGVEQVNNELCRLSLE
EEEEEEEECCHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHEEECC
KSGS
CCCC
>Mature Secondary Structure 
PATYPEYPSSLSYSAMEAQIREFWIERNIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHH
HLFSRTIKDVVCRYHTMQGYQVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFN
HHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCEEEEEHHHCCCCCHHHHHHCCCCCCC
REARALVYHHIDDNREGWGKLTERMGYWVDMDSPYITCDNNYIESVWWALKTIFDKGLIY
CCCEEEEEEECCCCCCHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEE
KDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYIKFRLKDSGESILVWTTTPWTLISNV
ECCEECCCCCCCCCHHCCCHHHCCHHHCCCCEEEEEEEEECCCCEEEEEECCCHHHHHHH
ALAVGRDIDYVRVKHRETGEVLILAESRLSVLVEKIGDESAWEVIDRCKGSDLEGRDYEP
HHHHCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCH
LFNYFSPERRAWYVVCGDFVSTGEGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCF
HHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHCCCCE
TAEVPDYEGMFFKDADKPIMQRLKEEGKLYRRETIQHTYPFSWRYDVPVIYYARESWYIR
EECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCEEEE
TTDIAPRMVALNKTINWNPPEIGTGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIG
ECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEECHHHHCCCCCCEEEECCEECC
DGPDSGKLFAVGSVAELREGFIEIDGEEMNLGDALDKGLVELDLHKPFVDRIWFIRDGKR
CCCCCCCEEEECCHHHHHCCCEEECCCCCCCHHHHHCCCEEEECCCCHHHHEEEEECCCC
FNRTPELIDVWFDSGSMPFAQLHYPFENKELFDKTFPADFIAEGVDQTRGWFYTLHAIAT
CCCCCCEEEEEECCCCCCHHEEECCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHH
LIFDRPAYRNVVVNGHILDKSGQKMSKSKGNVVDPFESMEQYGADAIRWYLMITSPPWRP
HHHCCCCCCEEEEEEEEECCCCCHHHHCCCCCCCHHHHHHHHCCCEEEEEEEEECCCCCC
KLFNAAEIEEEQRKFFRAFINSYNFFVLYANVDGFRYEEADIPFTQRSELDRWVLSSLNT
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHH
LIAEVTSRMEQYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTV
HHHHHHHHHHHHCCCHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LETLAKLMAPFVPFIAEKIWLDLKSVGGTSKAESVHLADWPVADESCIDAALEERMKKAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
IITSLVRTMREKAGIKVRQPLRRILLAAAEPGSRAAYELVSDIIKEEVNVQKIEYVEDED
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
GSVISKKAKPNFKTLGPRFGKDMKLLAEEIRIMSHKQISRLEKEGSIEIDLGGRICTVLR
CCEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHH
EDVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSRIQTLRKESGLEIT
HHHHHHHHCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DRIALTIAGSEKLLAAARKSESYIMDETLATSIVLLPLDDSQPGDGVEQVNNELCRLSLE
EEEEEEEECCHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHEEECC
KSGS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901