Click here to switch to the map view.

The map label for this gene is hup [H]

Identifier: 21673134

GI number: 21673134

Start: 307146

End: 307451

Strand: Reverse

Name: hup [H]

Synonym: CT0295

Alternate gene names: 21673134

Gene position: 307451-307146 (Counterclockwise)

Preceding gene: 21673135

Following gene: 21673131

Centisome position: 14.27

GC content: 49.67

Gene sequence:

>306_bases
ATGGGACAGACAACCACCAAAGCCGACCTGGTGAACGTGATCGCCCAACGCACAGGTCTGACCAAAAACGAAACCGAATC
GGTCGTTGATTGCTTGTTCGAAAGCATCATCGACTCGCTGAAAGCCGGAAAACGCATTGAAATCCGGGGATTTGGGTCGT
TCAACATTCGCTACAAGAATCTCCGGCAGGCAAGAAACCCAAGAACGGGTGAAAAGGTAACCGTCGAGCCAAAAAATGTG
CCGACCTTCAAAATCTCCAAAGAGTTCAAGCACGCGGTCAGCGAAAGCCTGAAAGCCAACAAATAA

Upstream 100 bases:

>100_bases
TTTTAAGAAGGATGTTCGCTGTTTTTCTTGTTTTAGTAGCAATCCGCCTTTGGTATTAACCAGCAGTATTGGCAAACCTA
TAACCCAAGCACACATTACC

Downstream 100 bases:

>100_bases
CCGCCACGGCAACACAACGCCGGCGAAGCGATGATCTTCACCGGAGGATATCCCATGCAAAAGAATCGGGCGGGGGTCAG
GATAACAGCGAAACGGAGAG

Product: DNA-binding protein HU-alpha, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 100

Protein sequence:

>101_residues
MGQTTTKADLVNVIAQRTGLTKNETESVVDCLFESIIDSLKAGKRIEIRGFGSFNIRYKNLRQARNPRTGEKVTVEPKNV
PTFKISKEFKHAVSESLKANK

Sequences:

>Translated_101_residues
MGQTTTKADLVNVIAQRTGLTKNETESVVDCLFESIIDSLKAGKRIEIRGFGSFNIRYKNLRQARNPRTGEKVTVEPKNV
PTFKISKEFKHAVSESLKANK
>Mature_100_residues
GQTTTKADLVNVIAQRTGLTKNETESVVDCLFESIIDSLKAGKRIEIRGFGSFNIRYKNLRQARNPRTGEKVTVEPKNVP
TFKISKEFKHAVSESLKANK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1787141, Length=86, Percent_Identity=43.0232558139535, Blast_Score=76, Evalue=4e-16,
Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788005, Length=88, Percent_Identity=35.2272727272727, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 11325; Mature: 11194

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQTTTKADLVNVIAQRTGLTKNETESVVDCLFESIIDSLKAGKRIEIRGFGSFNIRYKN
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHH
LRQARNPRTGEKVTVEPKNVPTFKISKEFKHAVSESLKANK
HHHHCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GQTTTKADLVNVIAQRTGLTKNETESVVDCLFESIIDSLKAGKRIEIRGFGSFNIRYKN
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHH
LRQARNPRTGEKVTVEPKNVPTFKISKEFKHAVSESLKANK
HHHHCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA