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The map label for this gene is celB [H]

Identifier: 21673118

GI number: 21673118

Start: 289681

End: 291063

Strand: Reverse

Name: celB [H]

Synonym: CT0279

Alternate gene names: 21673118

Gene position: 291063-289681 (Counterclockwise)

Preceding gene: 161485731

Following gene: 21673117

Centisome position: 13.51

GC content: 54.81

Gene sequence:

>1383_bases
ATGCAAGTCAAATTCGGAACCGATGGTTGGAGGGCAATTATAGCCAAAGAATACACTTACGACAATCTCAAGCTGGCCGC
TCTCGCTTCCGGAAAATATTTTCTCTCGCATCCGGACAAGTCAAATGGCGTTTGCGTCGGTTACGACACACGCTTCATGT
CGAAGGAGTTCGCCCGCTACACCGCGGAGGTGCTCTCGTCGATGGGTCTCAAGGTTTTCCTCTCCAGCAGCTTCGTTTCC
ACACCGGCGGTTTCGCTCTATACCAGGGAACACAAGCTCGCCGGCGGCGTCATGATCACTGCCTCGCACAATCCGCCGAT
CTACAACGGGTTCAAGGTCAAGGCCTCCTACGGCGGGCCGGCGCACCCGGAAGTGATCGACGAAATCGAGAAAAATCTGT
CCGGCATCGATCCCTCCACACTGGTAAAACCAGCGGAAAACCTGATCACCATGACCGACATCAAGTCGGAATATATTGCC
TATCTCGAATCGAAGCTGGACCTGAAGCTGATCCGCGAGTCGGGACTGAAGATCGCTCACAACGCCATGTACGGTGCGGG
TCAGGACATCGTCACCCGCCTGCTCGATGAATCGATGGTCAACTGCTACCACTGCTCGGTCAATCCGGGCTTCGACGGCA
TCAATCCCGAGCCGATTCCGCCATACATCACTGATTTCGTCGAGTTCTTCAAGGAAGTCGAGACCGACGTGGCGATCATC
AATGACGGCGACGCCGACCGCATCGGGATGCTCGACGAGAAGGGAGAATTCGTCGATTCGCATAAGCTCTTCGCCATCGT
CCTCAAATACCTTGTCGAACAGAAAGGCCAGCGTGGCGAAGTGGCCAAAACCTTTGCCCTGACCGACATTATCGACAGAA
TCTGCCAGAAACACGATTTGAAAATGCACCTGTTGCCGGTCGGCTTCAAATATGTCAGCCGCCTGATGACCACCAACGAC
ATTCTCATCGGCGGCGAAGAGTCCGGCGGCATCGGCATTACCTCGTTCCTGCCCGAGCGGGACGGCGTCTATACCGGCCT
CCTGATGCTTGAAATCATGGCACGGCGGCAGAAAACGCTTACCGGACTTGTCGAGGAACTGTATGACGAGTATGGCTTTT
TCAGTTACAACAGGCTTGATTTGCGAGTAGCCGAATCGAAGAAAGCGGCCATTATCGAAGCAGCGTCCGGAGGCAAGCTG
AAGAGCATCGCCGGTTATCCGGTCACCAGCTTCAACGACCTGGACGGCTTCAAATACCATTTCGAGGGCGGCTGGCTGCT
CATCAGGGCCTCGGGCACCGAGCCGGTGCTCAGGATTTATTGCGAAGCCGATTCCACTGAAAAAGTGGAAAAAGTGCTCG
CTTTCGCATCCAGACTCGCTTAA

Upstream 100 bases:

>100_bases
CATCATCGAACAGAAAACCGTATTTTGTGTCACGTTTGCGCTTCCGGATACCGGAAAAGGCCTTGGCCAGTCAACACCAT
TATATCAAATCTACTAGAGA

Downstream 100 bases:

>100_bases
AACAGCGCAAGAAACCCGGCAAAATGGCGTCTTACCGTGCGCCCGACACCGAACAGTTCCGGAAAACGCAAAACGCTTGC
GTTGATCTGAAAGACGACCC

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MQVKFGTDGWRAIIAKEYTYDNLKLAALASGKYFLSHPDKSNGVCVGYDTRFMSKEFARYTAEVLSSMGLKVFLSSSFVS
TPAVSLYTREHKLAGGVMITASHNPPIYNGFKVKASYGGPAHPEVIDEIEKNLSGIDPSTLVKPAENLITMTDIKSEYIA
YLESKLDLKLIRESGLKIAHNAMYGAGQDIVTRLLDESMVNCYHCSVNPGFDGINPEPIPPYITDFVEFFKEVETDVAII
NDGDADRIGMLDEKGEFVDSHKLFAIVLKYLVEQKGQRGEVAKTFALTDIIDRICQKHDLKMHLLPVGFKYVSRLMTTND
ILIGGEESGGIGITSFLPERDGVYTGLLMLEIMARRQKTLTGLVEELYDEYGFFSYNRLDLRVAESKKAAIIEAASGGKL
KSIAGYPVTSFNDLDGFKYHFEGGWLLIRASGTEPVLRIYCEADSTEKVEKVLAFASRLA

Sequences:

>Translated_460_residues
MQVKFGTDGWRAIIAKEYTYDNLKLAALASGKYFLSHPDKSNGVCVGYDTRFMSKEFARYTAEVLSSMGLKVFLSSSFVS
TPAVSLYTREHKLAGGVMITASHNPPIYNGFKVKASYGGPAHPEVIDEIEKNLSGIDPSTLVKPAENLITMTDIKSEYIA
YLESKLDLKLIRESGLKIAHNAMYGAGQDIVTRLLDESMVNCYHCSVNPGFDGINPEPIPPYITDFVEFFKEVETDVAII
NDGDADRIGMLDEKGEFVDSHKLFAIVLKYLVEQKGQRGEVAKTFALTDIIDRICQKHDLKMHLLPVGFKYVSRLMTTND
ILIGGEESGGIGITSFLPERDGVYTGLLMLEIMARRQKTLTGLVEELYDEYGFFSYNRLDLRVAESKKAAIIEAASGGKL
KSIAGYPVTSFNDLDGFKYHFEGGWLLIRASGTEPVLRIYCEADSTEKVEKVLAFASRLA
>Mature_460_residues
MQVKFGTDGWRAIIAKEYTYDNLKLAALASGKYFLSHPDKSNGVCVGYDTRFMSKEFARYTAEVLSSMGLKVFLSSSFVS
TPAVSLYTREHKLAGGVMITASHNPPIYNGFKVKASYGGPAHPEVIDEIEKNLSGIDPSTLVKPAENLITMTDIKSEYIA
YLESKLDLKLIRESGLKIAHNAMYGAGQDIVTRLLDESMVNCYHCSVNPGFDGINPEPIPPYITDFVEFFKEVETDVAII
NDGDADRIGMLDEKGEFVDSHKLFAIVLKYLVEQKGQRGEVAKTFALTDIIDRICQKHDLKMHLLPVGFKYVSRLMTTND
ILIGGEESGGIGITSFLPERDGVYTGLLMLEIMARRQKTLTGLVEELYDEYGFFSYNRLDLRVAESKKAAIIEAASGGKL
KSIAGYPVTSFNDLDGFKYHFEGGWLLIRASGTEPVLRIYCEADSTEKVEKVLAFASRLA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=384, Percent_Identity=29.4270833333333, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI290463102, Length=388, Percent_Identity=28.3505154639175, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI133922562, Length=379, Percent_Identity=28.2321899736148, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI290463104, Length=242, Percent_Identity=28.9256198347107, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI63055049, Length=539, Percent_Identity=23.9332096474954, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI31377548, Length=426, Percent_Identity=25.8215962441315, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1786904, Length=503, Percent_Identity=27.4353876739563, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789566, Length=473, Percent_Identity=26.8498942917548, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788361, Length=415, Percent_Identity=21.6867469879518, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17535441, Length=449, Percent_Identity=27.8396436525612, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71993870, Length=520, Percent_Identity=25.1923076923077, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71993878, Length=284, Percent_Identity=27.8169014084507, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323752, Length=406, Percent_Identity=27.8325123152709, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322722, Length=411, Percent_Identity=26.5206812652068, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323934, Length=292, Percent_Identity=28.4246575342466, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17864244, Length=481, Percent_Identity=26.6112266112266, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI20129809, Length=528, Percent_Identity=22.5378787878788, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651977, Length=425, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 51006; Mature: 51006

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKFGTDGWRAIIAKEYTYDNLKLAALASGKYFLSHPDKSNGVCVGYDTRFMSKEFARY
CEEEECCCCCEEEEEEECCCCCEEEEEEECCCEEEECCCCCCCEEEEECHHHHHHHHHHH
TAEVLSSMGLKVFLSSSFVSTPAVSLYTREHKLAGGVMITASHNPPIYNGFKVKASYGGP
HHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCCC
AHPEVIDEIEKNLSGIDPSTLVKPAENLITMTDIKSEYIAYLESKLDLKLIRESGLKIAH
CCHHHHHHHHHHHCCCCHHHHHCCHHHEEEHHHHHHHHHHHHHHHCHHHHHHHCCCEEEE
NAMYGAGQDIVTRLLDESMVNCYHCSVNPGFDGINPEPIPPYITDFVEFFKEVETDVAII
HHHCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
NDGDADRIGMLDEKGEFVDSHKLFAIVLKYLVEQKGQRGEVAKTFALTDIIDRICQKHDL
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
KMHLLPVGFKYVSRLMTTNDILIGGEESGGIGITSFLPERDGVYTGLLMLEIMARRQKTL
EEEEEECCHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
TGLVEELYDEYGFFSYNRLDLRVAESKKAAIIEAASGGKLKSIAGYPVTSFNDLDGFKYH
HHHHHHHHHHHCCCEECEEEEEEECCCCEEEEEECCCCCCCEECCCCCCCCCCCCCEEEE
FEGGWLLIRASGTEPVLRIYCEADSTEKVEKVLAFASRLA
ECCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVKFGTDGWRAIIAKEYTYDNLKLAALASGKYFLSHPDKSNGVCVGYDTRFMSKEFARY
CEEEECCCCCEEEEEEECCCCCEEEEEEECCCEEEECCCCCCCEEEEECHHHHHHHHHHH
TAEVLSSMGLKVFLSSSFVSTPAVSLYTREHKLAGGVMITASHNPPIYNGFKVKASYGGP
HHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCCC
AHPEVIDEIEKNLSGIDPSTLVKPAENLITMTDIKSEYIAYLESKLDLKLIRESGLKIAH
CCHHHHHHHHHHHCCCCHHHHHCCHHHEEEHHHHHHHHHHHHHHHCHHHHHHHCCCEEEE
NAMYGAGQDIVTRLLDESMVNCYHCSVNPGFDGINPEPIPPYITDFVEFFKEVETDVAII
HHHCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
NDGDADRIGMLDEKGEFVDSHKLFAIVLKYLVEQKGQRGEVAKTFALTDIIDRICQKHDL
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
KMHLLPVGFKYVSRLMTTNDILIGGEESGGIGITSFLPERDGVYTGLLMLEIMARRQKTL
EEEEEECCHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
TGLVEELYDEYGFFSYNRLDLRVAESKKAAIIEAASGGKLKSIAGYPVTSFNDLDGFKYH
HHHHHHHHHHHCCCEECEEEEEEECCCCEEEEEECCCCCCCEECCCCCCCCCCCCCEEEE
FEGGWLLIRASGTEPVLRIYCEADSTEKVEKVLAFASRLA
ECCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]