Click here to switch to the map view.

The map label for this gene is htrB [C]

Identifier: 21673052

GI number: 21673052

Start: 226994

End: 227926

Strand: Direct

Name: htrB [C]

Synonym: CT0211

Alternate gene names: 21673052

Gene position: 226994-227926 (Clockwise)

Preceding gene: 21673051

Following gene: 21673053

Centisome position: 10.53

GC content: 59.27

Gene sequence:

>933_bases
ATGAGCATCGAGCGAAACAGGCGCACAAAGAGAGTTAAACGCACCATGCGCTCGGCATCGAATACCGTGACCTATGGGGC
GGTCATGTTGCTTGGCGCTCTGGTTCGGAAGTTGAGCCGGAAACAGACCCGGCGTCTGGCCTGCGTCATCGGGGACTTCA
TGCACCGGGGCATCGGGCTCAGGCGGGATCTGGTTTACAGGAACCTCAGCCTGACCTTCCCTGAAAAATCTTCAGAAGAG
ATCGGCCGCATCGCGACGGCCATGTATCGCAATGTTGCCGGTACGCTGCTCGAAGTGCTGCGGCTGCCCTTGATCTGCAA
CCGCGACGACGCGGCGGCGCTGGTCGATATCAAAGGCGACGAAGCCTTCTGGGAGTGGCATCGTAGCGGGACGACGGGCG
CTGTGATGGTGTCAGCCCATTATGGCAACTGGGAGTTGATGGCGATGGCCTTCGGCCTGTTGATCTGCCCCGTTACCATT
ATCGTCAAGCGGCTGCGCAACGAACGGGTTGATCGCAAGATGAACGAGTACCGGACCATGCGCGGCAACAGCGTGGTCTA
TCCGAAGCAGTCGGTCAGGGAGGGCTTGCGCCTGTTGCAGAGCGGCGGTACACTGGCCATTCTCGGTGATCAGTCCGATC
CCGATGAAGTCAATTTCGGCGAGTTTCTCGGTCGTCGCACCACCATGTTCCACGGCGCAGCCTTCTTTGCGCTCCGGGCG
AACGTGCCATTGTTTGTGCCCACGTGCACCAGTAACGGTGATGGACGGTACACGATCAACATTACTCGGGTCAACACCGC
TGACCTTACATTCAACAAGGCCGATATTGCCACGCTCGCCGTACGCTACACCAGCGCGATCGAAGCACAGATTCGCCGTC
GTCCCGAGGAATGGTTCTGGCTGCACGACCGCTGGAAGCGGGGTCGTGATTGA

Upstream 100 bases:

>100_bases
TTGCTTATTCAGGCGCAGTGCGGCCCTTTTTGACCGTTTTCCGGGATAAAGGATGATTTCAAAGTATGGTGGTTATGAAT
ATGAATGAGGTGCGTGTTTC

Downstream 100 bases:

>100_bases
GGAAAAAGTGGATTTTCAGTATTCTTGATTATTGACGCACACACTTTATGAACGCAGGGAAAAAAGGCGTTATCTACACC
TGTATTACTGGTGGGTATGA

Product: acyltransferase

Products: NA

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Acyltransferase HtrB/MsbB Family; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Lipd A Biosynthesis Related Exported Protein; Lipid A Biosynthesis-Lipid IVA Acyltransferase; Lauroyl Acyltransferase; Lipid A Lauroyl Acyltransferase Protein

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSIERNRRTKRVKRTMRSASNTVTYGAVMLLGALVRKLSRKQTRRLACVIGDFMHRGIGLRRDLVYRNLSLTFPEKSSEE
IGRIATAMYRNVAGTLLEVLRLPLICNRDDAAALVDIKGDEAFWEWHRSGTTGAVMVSAHYGNWELMAMAFGLLICPVTI
IVKRLRNERVDRKMNEYRTMRGNSVVYPKQSVREGLRLLQSGGTLAILGDQSDPDEVNFGEFLGRRTTMFHGAAFFALRA
NVPLFVPTCTSNGDGRYTINITRVNTADLTFNKADIATLAVRYTSAIEAQIRRRPEEWFWLHDRWKRGRD

Sequences:

>Translated_310_residues
MSIERNRRTKRVKRTMRSASNTVTYGAVMLLGALVRKLSRKQTRRLACVIGDFMHRGIGLRRDLVYRNLSLTFPEKSSEE
IGRIATAMYRNVAGTLLEVLRLPLICNRDDAAALVDIKGDEAFWEWHRSGTTGAVMVSAHYGNWELMAMAFGLLICPVTI
IVKRLRNERVDRKMNEYRTMRGNSVVYPKQSVREGLRLLQSGGTLAILGDQSDPDEVNFGEFLGRRTTMFHGAAFFALRA
NVPLFVPTCTSNGDGRYTINITRVNTADLTFNKADIATLAVRYTSAIEAQIRRRPEEWFWLHDRWKRGRD
>Mature_309_residues
SIERNRRTKRVKRTMRSASNTVTYGAVMLLGALVRKLSRKQTRRLACVIGDFMHRGIGLRRDLVYRNLSLTFPEKSSEEI
GRIATAMYRNVAGTLLEVLRLPLICNRDDAAALVDIKGDEAFWEWHRSGTTGAVMVSAHYGNWELMAMAFGLLICPVTII
VKRLRNERVDRKMNEYRTMRGNSVVYPKQSVREGLRLLQSGGTLAILGDQSDPDEVNFGEFLGRRTTMFHGAAFFALRAN
VPLFVPTCTSNGDGRYTINITRVNTADLTFNKADIATLAVRYTSAIEAQIRRRPEEWFWLHDRWKRGRD

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.-

Molecular weight: Translated: 35349; Mature: 35218

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIERNRRTKRVKRTMRSASNTVTYGAVMLLGALVRKLSRKQTRRLACVIGDFMHRGIGL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRDLVYRNLSLTFPEKSSEEIGRIATAMYRNVAGTLLEVLRLPLICNRDDAAALVDIKGD
HHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCC
EAFWEWHRSGTTGAVMVSAHYGNWELMAMAFGLLICPVTIIVKRLRNERVDRKMNEYRTM
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGNSVVYPKQSVREGLRLLQSGGTLAILGDQSDPDEVNFGEFLGRRTTMFHGAAFFALRA
CCCEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCHHHHHHHHEEEEEEC
NVPLFVPTCTSNGDGRYTINITRVNTADLTFNKADIATLAVRYTSAIEAQIRRRPEEWFW
CCCEEEEECCCCCCCEEEEEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCHHHEE
LHDRWKRGRD
EHHHHCCCCC
>Mature Secondary Structure 
SIERNRRTKRVKRTMRSASNTVTYGAVMLLGALVRKLSRKQTRRLACVIGDFMHRGIGL
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRDLVYRNLSLTFPEKSSEEIGRIATAMYRNVAGTLLEVLRLPLICNRDDAAALVDIKGD
HHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCC
EAFWEWHRSGTTGAVMVSAHYGNWELMAMAFGLLICPVTIIVKRLRNERVDRKMNEYRTM
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGNSVVYPKQSVREGLRLLQSGGTLAILGDQSDPDEVNFGEFLGRRTTMFHGAAFFALRA
CCCEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCHHHHHHHHEEEEEEC
NVPLFVPTCTSNGDGRYTINITRVNTADLTFNKADIATLAVRYTSAIEAQIRRRPEEWFW
CCCEEEEECCCCCCCEEEEEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCHHHEE
LHDRWKRGRD
EHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA