Click here to switch to the map view.

The map label for this gene is rssA [H]

Identifier: 21673036

GI number: 21673036

Start: 205732

End: 207066

Strand: Direct

Name: rssA [H]

Synonym: CT0195

Alternate gene names: 21673036

Gene position: 205732-207066 (Clockwise)

Preceding gene: 21673035

Following gene: 21673038

Centisome position: 9.55

GC content: 66.89

Gene sequence:

>1335_bases
ATGGATGGTCGAAAAACAGCCATGACGCCCTCGCTGCAACGGCGTCTGACCGCGATGCTGGCCGGGGCGATCGTGCTGGC
GGCACTGGTCGCGGCGGCGACTTCGTTCTATTTTTCCTACCGCGAGGCCAAAGAGTTTCAGGACGACATGCTCCGCCAGA
TCGCGGTGCTTCAGTCTCGCGGCGAGTGGGAGACCGTTGGAGCCGGAGCATTGTCAGTCCCCTCGTCTTCGGCCTCTCTG
AGCGATCCCGAGTCCAGAATCACGATTTTTCATTTCACTGACCGATCCGCGCCGCGCTGGCTTGCCGGGCATCTCGCGCC
CGGCTTTCACACGCTCCGGCAGGAGGGCGAACCGGTGCGGGTGTTCATCGTTCACGGGCCGTCCGCGATGACGGCGGTCG
CGCAACCGACCGATACGCGCGATGAACTCGCGCTCAACAGCGCCTTGCGCACGCTCGCGCCGGGCCTGTTGCTGCTGCCG
CTCATGGCGCTGCTCGTCATGCGCATCGTCCGTTCCGCGCTCAAGCCCGTCACCACGCTGTCGCGCCTGCTCGACCAGCA
GCAGCCCGGCCAGCCGGTTCCGCTGCCGGAGCGCGGCATTCCCGAAGAGATAATGCCGTTCGTGGAGGCGCTCAACCGGC
TGCTTGGGCGCATTTCACTTTTGCTTGGCCAGCAGCGGCGTTTCATTGCCGACGCGGCCCACGAGCTGCGCAGTCCGCTG
ACGGCGCTCTCCCTTCAGGCGGAGAATCTCCGGCAGGCGTCAAGCGCCGACCAGATGCGCGCCCGGCTTGTGCCGCTTCA
GTCGGGCATCGAACGCGCCCGCCAGCTTACCGCGCAGCTTCTCGATCTGGCGCGGGTGCAGGCGCACCCTTCCGGCGCGG
CTCCGGTCGATCTTCCGGCGCTGGCGCGAGAGCTGATCGCCGGGTACCTGCCGCTGGCGGAGGCTCGCGGCATCGATCTC
GGCCTTGACGATTCAGGCCCGGTGTTGCTCGACGGCGATCCTGAAAGCTTCACGCTGATTCTGAAAAACGGCCTCGAAAA
CGCCCTGAAATACGTTCAGCCGGGCGGAACGGTGACGGTCAGGCTCGCCGTCGAACATGGCGACGGAATCGCGGAGGTGA
TCGATAACGGCCCCGGCATTCCGGAGAGCGAGCGGGAGCGGGTGTTCGATGCGTTTTACCGCACGCCCGGTTCCGGCCAG
CCCGGCAGCGGCCTCGGCCTGACTATCGCGCGCGAAGCTGCCCGCTCGCTCGGCGGCGACCTCCGTGTGCTGTCTGGCCC
CGATGGCCAGGGCACGGTATTTCGCTACCGGCAACGCGGGCGCGAAGCCGGGTGA

Upstream 100 bases:

>100_bases
GCTGGGACGAGGAGGTCGAGAGCAACGCCATCGATTACCTGATCCACCAGCTCCGCCGCAAGCTCGGCGCGACGAGCATC
AAAAACATACGGGGTGCGGG

Downstream 100 bases:

>100_bases
TTTTTGGAGCTGGAATTCTTCCTTGAAAAAAACTGCAATTGCATTGCCGATCGCTGGTTTATCGATTATCCGGCGGTTGC
CGAACGGTGATGCTCCGCTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MDGRKTAMTPSLQRRLTAMLAGAIVLAALVAAATSFYFSYREAKEFQDDMLRQIAVLQSRGEWETVGAGALSVPSSSASL
SDPESRITIFHFTDRSAPRWLAGHLAPGFHTLRQEGEPVRVFIVHGPSAMTAVAQPTDTRDELALNSALRTLAPGLLLLP
LMALLVMRIVRSALKPVTTLSRLLDQQQPGQPVPLPERGIPEEIMPFVEALNRLLGRISLLLGQQRRFIADAAHELRSPL
TALSLQAENLRQASSADQMRARLVPLQSGIERARQLTAQLLDLARVQAHPSGAAPVDLPALARELIAGYLPLAEARGIDL
GLDDSGPVLLDGDPESFTLILKNGLENALKYVQPGGTVTVRLAVEHGDGIAEVIDNGPGIPESERERVFDAFYRTPGSGQ
PGSGLGLTIAREAARSLGGDLRVLSGPDGQGTVFRYRQRGREAG

Sequences:

>Translated_444_residues
MDGRKTAMTPSLQRRLTAMLAGAIVLAALVAAATSFYFSYREAKEFQDDMLRQIAVLQSRGEWETVGAGALSVPSSSASL
SDPESRITIFHFTDRSAPRWLAGHLAPGFHTLRQEGEPVRVFIVHGPSAMTAVAQPTDTRDELALNSALRTLAPGLLLLP
LMALLVMRIVRSALKPVTTLSRLLDQQQPGQPVPLPERGIPEEIMPFVEALNRLLGRISLLLGQQRRFIADAAHELRSPL
TALSLQAENLRQASSADQMRARLVPLQSGIERARQLTAQLLDLARVQAHPSGAAPVDLPALARELIAGYLPLAEARGIDL
GLDDSGPVLLDGDPESFTLILKNGLENALKYVQPGGTVTVRLAVEHGDGIAEVIDNGPGIPESERERVFDAFYRTPGSGQ
PGSGLGLTIAREAARSLGGDLRVLSGPDGQGTVFRYRQRGREAG
>Mature_444_residues
MDGRKTAMTPSLQRRLTAMLAGAIVLAALVAAATSFYFSYREAKEFQDDMLRQIAVLQSRGEWETVGAGALSVPSSSASL
SDPESRITIFHFTDRSAPRWLAGHLAPGFHTLRQEGEPVRVFIVHGPSAMTAVAQPTDTRDELALNSALRTLAPGLLLLP
LMALLVMRIVRSALKPVTTLSRLLDQQQPGQPVPLPERGIPEEIMPFVEALNRLLGRISLLLGQQRRFIADAAHELRSPL
TALSLQAENLRQASSADQMRARLVPLQSGIERARQLTAQLLDLARVQAHPSGAAPVDLPALARELIAGYLPLAEARGIDL
GLDDSGPVLLDGDPESFTLILKNGLENALKYVQPGGTVTVRLAVEHGDGIAEVIDNGPGIPESERERVFDAFYRTPGSGQ
PGSGLGLTIAREAARSLGGDLRVLSGPDGQGTVFRYRQRGREAG

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=321, Percent_Identity=33.6448598130841, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=28.4210526315789, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786783, Length=286, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082128, Length=303, Percent_Identity=27.3927392739274, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=221, Percent_Identity=28.9592760180996, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=303, Percent_Identity=27.7227722772277, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786912, Length=214, Percent_Identity=32.2429906542056, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790346, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=28.8990825688073, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=221, Percent_Identity=30.316742081448, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=28.4, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787374, Length=229, Percent_Identity=30.1310043668122, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788549, Length=214, Percent_Identity=29.9065420560748, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=303, Percent_Identity=23.7623762376238, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=25.5144032921811, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=27.9279279279279, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47742; Mature: 47742

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRKTAMTPSLQRRLTAMLAGAIVLAALVAAATSFYFSYREAKEFQDDMLRQIAVLQSR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEWETVGAGALSVPSSSASLSDPESRITIFHFTDRSAPRWLAGHLAPGFHTLRQEGEPVR
CCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHCCCCCEE
VFIVHGPSAMTAVAQPTDTRDELALNSALRTLAPGLLLLPLMALLVMRIVRSALKPVTTL
EEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLLDQQQPGQPVPLPERGIPEEIMPFVEALNRLLGRISLLLGQQRRFIADAAHELRSPL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TALSLQAENLRQASSADQMRARLVPLQSGIERARQLTAQLLDLARVQAHPSGAAPVDLPA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LARELIAGYLPLAEARGIDLGLDDSGPVLLDGDPESFTLILKNGLENALKYVQPGGTVTV
HHHHHHHHHCCHHHHCCCEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
RLAVEHGDGIAEVIDNGPGIPESERERVFDAFYRTPGSGQPGSGLGLTIAREAARSLGGD
EEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCC
LRVLSGPDGQGTVFRYRQRGREAG
EEEEECCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MDGRKTAMTPSLQRRLTAMLAGAIVLAALVAAATSFYFSYREAKEFQDDMLRQIAVLQSR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEWETVGAGALSVPSSSASLSDPESRITIFHFTDRSAPRWLAGHLAPGFHTLRQEGEPVR
CCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHCCCCCEE
VFIVHGPSAMTAVAQPTDTRDELALNSALRTLAPGLLLLPLMALLVMRIVRSALKPVTTL
EEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLLDQQQPGQPVPLPERGIPEEIMPFVEALNRLLGRISLLLGQQRRFIADAAHELRSPL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TALSLQAENLRQASSADQMRARLVPLQSGIERARQLTAQLLDLARVQAHPSGAAPVDLPA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LARELIAGYLPLAEARGIDLGLDDSGPVLLDGDPESFTLILKNGLENALKYVQPGGTVTV
HHHHHHHHHCCHHHHCCCEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
RLAVEHGDGIAEVIDNGPGIPESERERVFDAFYRTPGSGQPGSGLGLTIAREAARSLGGD
EEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCC
LRVLSGPDGQGTVFRYRQRGREAG
EEEEECCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA