Click here to switch to the map view.

The map label for this gene is rpoB

Identifier: 21672996

GI number: 21672996

Start: 155842

End: 159753

Strand: Direct

Name: rpoB

Synonym: CT0155

Alternate gene names: 21672996

Gene position: 155842-159753 (Clockwise)

Preceding gene: 21672995

Following gene: 21672997

Centisome position: 7.23

GC content: 56.7

Gene sequence:

>3912_bases
GTGAAAGTGGCTGATGCAACACCAACACCGTGTATTGACTTTTCCAAGATCCAGAGTATCATAAATCCCCCCGACCTTCT
CAAGGTACAGCTCGATTCGTTTCATAATTTCATCCAGGACAGCGTTCCCCTTGAAAAACGCAAGGATCAGGGGCTTGAAA
AAGTGCTCAGGAGCGCCTTTCCCATTACCGATACCAGGGGGCTCTATCTCCTGGAATATATCTCCTACAGCTTCGACAAG
CCGAAATATACCGTCGAGGAGTGCATTGAGCGCGGCCTGACCTACGATGTTTCGCTCAAGATCAAGCTCAAGCTCTCCTA
TAAGGATGAGGCCGACGAGCCGGACTGGAAGGAGACCATCCAGCAGGAGGTCTATCTCGGCAGGATTCCCTATATGACCG
ACCGCGGGACCTTTATCATCAACGGCGCCGAGCGCGTCGTGGTGGCGCAGCTTCACCGTTCGCCGGGCGTGGTGTTCAGC
GAGGCCGTACACCCGAACGGTAAAAAGATGTACTCGGCCAAAATCGTGCCGACTCGCGGTTCCTGGATCGAGTTCCAGAC
CGACATCAACAACCAGATTTTCGTCTACATCGACCAGAAGAAGAACTTCCTGGTCACAGCGCTGCTCAGGGCGATCGGTT
TTGCCAAGGATGAGGATATTCTCGGACTGTTCGATCTGGTCGAGGAGGTCGAGGTTTCGTCCAAGAGCTCGAAGCGCGAG
CAGCTTCTTGGCCAGTATCTGGCTTCCGATATCATCGACATGACTACCGGTGAGGTAGTGCCTGCAAGGGCAGCCATTAC
CGAGGAGATCATAGACCAGATCGTCGCTGCCGGTTACAAAACGGTCAAGGTGATGAAGACCACCTCCCCCGAGAAAGGCG
TGGACAAGTCGGTTATCATCAACACGATTCTCAATGACAGTTCCGCCACCGAGGAAGAGGCGCTTGAAATTGTCTACGAG
GAGCTTCGCTCCAACGAAGCGCCGGACATCGATGCCGCCAGAAGCTTCCTCGAACGCACCTTTTTCAATCAGAAGAAATA
CGATCTCGGCGATGTTGGTCGCTATCGCATTCAGAAGAAGCTTCAGAACGAGCTTGCCGAGCTTTCGGCTTATCTTGAAA
AGCGCCCTGAACTGAAGGAACTCTCCGACGCTATTTACGAGCGCATTCTCCAGACGATCAGCACCTACTCCGAGGAGCCG
ATCGGTGAGGATATTCTGGTGCTGACCCACTACGACATCATTGCGGTCATCAATTATCTGATCAAGCTGATCAACGGCAT
GGCCGAGGTCGATGACGTCGATCACCTGGCCAACCGCCGCGTGCGCTCGGTGGGCGAGCAACTCGCTGCGCAGTTCGTGA
TCGGTCTGGCGAGAATGGGCAAGAATGTTCGCGAAAAGCTCAACTCGCGCGATACCGACAAGATCGCTCCGGCTGATCTG
ATCAATGCGCGAACCGTGTCGAGCGTGGTGTCGAGCTTCTTTGCCACCAGCCAGCTCTCGCAGTTTATGGACCAGACCAA
TCCTCTGGCCGAAATGACCAACAAGCGCAGGGTTTCGGCTCTTGGCCCCGGTGGCCTGACCCGCGAGCGTGCAGGTTTCG
AGGTTCGCGATGTTCACTACACTCATTACGGACGTCTTTGCCCGATCGAGACCCCTGAAGGCCCGAACATCGGTCTGATT
TCGTCGCTGTCGGTCTATGCCGAAATCAACGACAAGGGCTTCATCCAGACCCCGTACCGCGTGGTCGAAAATGGTCAGGT
CACCGACAAGGTCGTGATGCTCTCCGCAGAGGATGAGGAGAACAAGATCACCGTGCCGGTCAGCATCGAGCTTGACGAGA
ACAACCGCATCGCGGCCGAGTCGGTGCAGGCCAGAACCAAGGGTGACTACCCGCTGGTGCTTGCCGAAGAGGTCAACTAC
ATGGACGTCTCTCCGGTTCAGATTGTCAGCGCGGCAGCCGCGCTCATCCCGTTCCTTGAGCACGATGACGGTAACCGCGC
GCTCATGGGCGCGAACATGCAGCGCCAGGCAGTGCCGCTGCTCGTTTCCGAAGCGCCGATCGTTGGCACCGGCATGGAGG
CCAAGGTGGCCCGTGATTCTCGCGCGGTGATCGTGGCCGAGGGGCCCGGCGTGGTGCAGTGCGTCACGGCGGATCGCATC
GAAGTGCGCTACGATCTCGATCCGGAAAACAACACCGTTTCGTTGCTTGACCCAGACGAAGGCGTCAAGGTCTACAAGCT
CATCAAATTCAAGCGCTCCAACCAGGACACCTGCATCTCGCAGCGCCCGCTGGTGCACAATGGCCAGAGGGTCAACGCCG
GCGACGTGCTGGCCGACAGCTCCTCGACCGACAATGGCGAACTGGCGCTCGGTAAAAACGTGCTGGTAGCCTTCATGCCC
TGGCGCGGTTACAACTTCGAGGACGCTATTGTGCTCAGTGAGCGCCTCGTCTATGACGACGTCTTTACCTCGATCCACGT
GCACGAGTTCGAGTCGAGCGTGCGCGACACCAAGCGCGGCGAGGAGCAATTTACTCGCGACATCTACAACGTCAGCGAGG
ATGCGCTGCGCAACCTCGACGAGAACGGCATCGTGCGCATCGGCGCCGAGGTCAAGGAGCGCGACATTCTGGTCGGTAAG
ATCACCCCGAAAGGCGAGAGCGATCCGACTCCGGAAGAAAAGCTCCTGCGTGCCATCTTCGGCGACAAGTCGAGCGACGT
GAAAGACGCCTCGATGCACGTGCCGGCCGGCATGAAAGGTATCGTCATCAAGACCAAGCTGTTCAGCCGCAAGAAAAAGA
TCGGCATGGACGTAAAAGAGCGCATGGAGGCGATCGACAAGCAGTTCGATCTGAAAGAGGCCGACCTGCGCAGCCGCTTT
GCCAAATGGATGAAGCAGTATCTCAACGGCAAGAAGAGCGTTGCCATCACCAGCGACAAAGGCAAGGTGCTCGTTCCCGA
AGGCACGGTCATCGATGAAGCGCTGCTGGCCAAGTTCAACGGCTTGCCGTTCCTCGAATCGATTGATCTGTCGAAAGGCA
TTGTGAGCGGAGCCAAAACCAACGAAAACGTCGTCCGCCTGATTCGTGAATACCGTCTCAAGCTGAAGGATCTGTCTGAC
GAGCGTGAGAACGAGAAGTACAAAATCAACGTCGGCGATGAATTGCCGCCCGGTATCGAAGAGTTGGCCAAGGTTTATAT
CGCCCAGAAGAGGAAAATCCAGGTGGGTGACAAGATGGCCGGTCGTCACGGTAACAAGGGTGTGGTCGGCAAGATTCTGC
CGATCGAGGATATGCCCTTCATGGAGGATGGGACCCCGGTCGATATCGTGCTCAACCCGCTTGGTGTGCCGAGCCGTATG
AACATCGGCCAGCTGTACGAAACCTCGCTCGGCTGGGCGGGCAAGAAGCTCGGTGTCAAGTTCAAGACCCCGATCTTCAG
CGGTGCAACCTACACCGAGGTGCAGGAGTATCTTGAAAAAGCTGGTCTGCCTGGGCACGGCAAGGTCAAGCTGTTCGACG
GACGTACCGGCGAGCAGTTCCACGACGAGGTCACGGTTGGTTATATCTACATGCTCAAACTGAGCCACCTGGTCGACGAC
AAGATTCATGCTAGGTCCATCGGACCATACTCGCTTATCACCCAGCAGCCGCTCGGTGGCAAGGCACAGTTCGGTGGCCA
AAGGTTTGGTGAAATGGAGGTCTGGGCGCTCGAAGCCTACGGCGCGGCCAACATCCTGCGAGAGATGCTCACGGTCAAAT
CCGATGACGTGATCGGCAGGAACAAAACCTATGAAGCGATTGTCAAGGGACAGAATCTTCCGGAACCCGGAACGCCTGAA
TCGTTCAACGTGCTTATCAGGGAGCTGCAGGGGCTTGGCCTCGAGATCAGGATCGACGACAGAGTGCCCTGA

Upstream 100 bases:

>100_bases
GCGAATACATATTGGTTGCGACTTCGAACGATGAGACCTGAAAGAGAATTGCCCATTAACTGTTAAGTACTCCCTGCAAT
TGACTAAAAGCGAGGTGCAT

Downstream 100 bases:

>100_bases
AATGATGTAACGATATGCCGGATCGATCACTTCGGCAATTGAAAAGAAGTAACGAAGATAATTTCAAGGTTGTTTTAACA
GGGATATCGACCATGATATT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1303; Mature: 1303

Protein sequence:

>1303_residues
MKVADATPTPCIDFSKIQSIINPPDLLKVQLDSFHNFIQDSVPLEKRKDQGLEKVLRSAFPITDTRGLYLLEYISYSFDK
PKYTVEECIERGLTYDVSLKIKLKLSYKDEADEPDWKETIQQEVYLGRIPYMTDRGTFIINGAERVVVAQLHRSPGVVFS
EAVHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVEVSSKSSKRE
QLLGQYLASDIIDMTTGEVVPARAAITEEIIDQIVAAGYKTVKVMKTTSPEKGVDKSVIINTILNDSSATEEEALEIVYE
ELRSNEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIQKKLQNELAELSAYLEKRPELKELSDAIYERILQTISTYSEEP
IGEDILVLTHYDIIAVINYLIKLINGMAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDTDKIAPADL
INARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLI
SSLSVYAEINDKGFIQTPYRVVENGQVTDKVVMLSAEDEENKITVPVSIELDENNRIAAESVQARTKGDYPLVLAEEVNY
MDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLVSEAPIVGTGMEAKVARDSRAVIVAEGPGVVQCVTADRI
EVRYDLDPENNTVSLLDPDEGVKVYKLIKFKRSNQDTCISQRPLVHNGQRVNAGDVLADSSSTDNGELALGKNVLVAFMP
WRGYNFEDAIVLSERLVYDDVFTSIHVHEFESSVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGK
ITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKIGMDVKERMEAIDKQFDLKEADLRSRF
AKWMKQYLNGKKSVAITSDKGKVLVPEGTVIDEALLAKFNGLPFLESIDLSKGIVSGAKTNENVVRLIREYRLKLKDLSD
ERENEKYKINVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMEDGTPVDIVLNPLGVPSRM
NIGQLYETSLGWAGKKLGVKFKTPIFSGATYTEVQEYLEKAGLPGHGKVKLFDGRTGEQFHDEVTVGYIYMLKLSHLVDD
KIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQNLPEPGTPE
SFNVLIRELQGLGLEIRIDDRVP

Sequences:

>Translated_1303_residues
MKVADATPTPCIDFSKIQSIINPPDLLKVQLDSFHNFIQDSVPLEKRKDQGLEKVLRSAFPITDTRGLYLLEYISYSFDK
PKYTVEECIERGLTYDVSLKIKLKLSYKDEADEPDWKETIQQEVYLGRIPYMTDRGTFIINGAERVVVAQLHRSPGVVFS
EAVHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVEVSSKSSKRE
QLLGQYLASDIIDMTTGEVVPARAAITEEIIDQIVAAGYKTVKVMKTTSPEKGVDKSVIINTILNDSSATEEEALEIVYE
ELRSNEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIQKKLQNELAELSAYLEKRPELKELSDAIYERILQTISTYSEEP
IGEDILVLTHYDIIAVINYLIKLINGMAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDTDKIAPADL
INARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLI
SSLSVYAEINDKGFIQTPYRVVENGQVTDKVVMLSAEDEENKITVPVSIELDENNRIAAESVQARTKGDYPLVLAEEVNY
MDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLVSEAPIVGTGMEAKVARDSRAVIVAEGPGVVQCVTADRI
EVRYDLDPENNTVSLLDPDEGVKVYKLIKFKRSNQDTCISQRPLVHNGQRVNAGDVLADSSSTDNGELALGKNVLVAFMP
WRGYNFEDAIVLSERLVYDDVFTSIHVHEFESSVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGK
ITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKIGMDVKERMEAIDKQFDLKEADLRSRF
AKWMKQYLNGKKSVAITSDKGKVLVPEGTVIDEALLAKFNGLPFLESIDLSKGIVSGAKTNENVVRLIREYRLKLKDLSD
ERENEKYKINVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMEDGTPVDIVLNPLGVPSRM
NIGQLYETSLGWAGKKLGVKFKTPIFSGATYTEVQEYLEKAGLPGHGKVKLFDGRTGEQFHDEVTVGYIYMLKLSHLVDD
KIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQNLPEPGTPE
SFNVLIRELQGLGLEIRIDDRVP
>Mature_1303_residues
MKVADATPTPCIDFSKIQSIINPPDLLKVQLDSFHNFIQDSVPLEKRKDQGLEKVLRSAFPITDTRGLYLLEYISYSFDK
PKYTVEECIERGLTYDVSLKIKLKLSYKDEADEPDWKETIQQEVYLGRIPYMTDRGTFIINGAERVVVAQLHRSPGVVFS
EAVHPNGKKMYSAKIVPTRGSWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVEVSSKSSKRE
QLLGQYLASDIIDMTTGEVVPARAAITEEIIDQIVAAGYKTVKVMKTTSPEKGVDKSVIINTILNDSSATEEEALEIVYE
ELRSNEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIQKKLQNELAELSAYLEKRPELKELSDAIYERILQTISTYSEEP
IGEDILVLTHYDIIAVINYLIKLINGMAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDTDKIAPADL
INARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLI
SSLSVYAEINDKGFIQTPYRVVENGQVTDKVVMLSAEDEENKITVPVSIELDENNRIAAESVQARTKGDYPLVLAEEVNY
MDVSPVQIVSAAAALIPFLEHDDGNRALMGANMQRQAVPLLVSEAPIVGTGMEAKVARDSRAVIVAEGPGVVQCVTADRI
EVRYDLDPENNTVSLLDPDEGVKVYKLIKFKRSNQDTCISQRPLVHNGQRVNAGDVLADSSSTDNGELALGKNVLVAFMP
WRGYNFEDAIVLSERLVYDDVFTSIHVHEFESSVRDTKRGEEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGK
ITPKGESDPTPEEKLLRAIFGDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKIGMDVKERMEAIDKQFDLKEADLRSRF
AKWMKQYLNGKKSVAITSDKGKVLVPEGTVIDEALLAKFNGLPFLESIDLSKGIVSGAKTNENVVRLIREYRLKLKDLSD
ERENEKYKINVGDELPPGIEELAKVYIAQKRKIQVGDKMAGRHGNKGVVGKILPIEDMPFMEDGTPVDIVLNPLGVPSRM
NIGQLYETSLGWAGKKLGVKFKTPIFSGATYTEVQEYLEKAGLPGHGKVKLFDGRTGEQFHDEVTVGYIYMLKLSHLVDD
KIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGRNKTYEAIVKGQNLPEPGTPE
SFNVLIRELQGLGLEIRIDDRVP

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=203, Percent_Identity=42.3645320197044, Blast_Score=154, Evalue=5e-37,
Organism=Homo sapiens, GI238908503, Length=203, Percent_Identity=42.3645320197044, Blast_Score=154, Evalue=7e-37,
Organism=Homo sapiens, GI4505941, Length=196, Percent_Identity=38.7755102040816, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI33469941, Length=259, Percent_Identity=32.4324324324324, Blast_Score=137, Evalue=9e-32,
Organism=Homo sapiens, GI212286172, Length=259, Percent_Identity=32.4324324324324, Blast_Score=137, Evalue=9e-32,
Organism=Escherichia coli, GI1790419, Length=1406, Percent_Identity=46.0170697012802, Blast_Score=1136, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=249, Percent_Identity=38.1526104417671, Blast_Score=157, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17552304, Length=196, Percent_Identity=38.265306122449, Blast_Score=139, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17506623, Length=185, Percent_Identity=37.2972972972973, Blast_Score=130, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324781, Length=249, Percent_Identity=35.7429718875502, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324725, Length=195, Percent_Identity=37.4358974358974, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6325267, Length=213, Percent_Identity=40.8450704225352, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17647877, Length=194, Percent_Identity=40.2061855670103, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17136444, Length=257, Percent_Identity=34.2412451361868, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17136446, Length=200, Percent_Identity=35, Blast_Score=119, Evalue=2e-26,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_CHLTE (Q8KG15)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661061.1
- ProteinModelPortal:   Q8KG15
- GeneID:   1007129
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0155
- NMPDR:   fig|194439.1.peg.155
- TIGR:   CT0155
- HOGENOM:   HBG285547
- OMA:   IGRNKTY
- ProtClustDB:   PRK00405
- BioCyc:   CTEP194439:CT_0155-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 145471; Mature: 145471

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVADATPTPCIDFSKIQSIINPPDLLKVQLDSFHNFIQDSVPLEKRKDQGLEKVLRSAF
CCCCCCCCCCCCCHHHHHHHCCCCHHEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PITDTRGLYLLEYISYSFDKPKYTVEECIERGLTYDVSLKIKLKLSYKDEADEPDWKETI
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCHHHHHH
QQEVYLGRIPYMTDRGTFIINGAERVVVAQLHRSPGVVFSEAVHPNGKKMYSAKIVPTRG
HHHHHHCCCCEEECCCEEEECCCCEEEEEEHHCCCCCEEECCCCCCCCEEEEEEEEECCC
SWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVEVSSKSSKRE
CEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHH
QLLGQYLASDIIDMTTGEVVPARAAITEEIIDQIVAAGYKTVKVMKTTSPEKGVDKSVII
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHH
NTILNDSSATEEEALEIVYEELRSNEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIQKK
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LQNELAELSAYLEKRPELKELSDAIYERILQTISTYSEEPIGEDILVLTHYDIIAVINYL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
IKLINGMAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDTDKIAPADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHH
INARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCHHHCCCEEEEEEE
THYGRLCPIETPEGPNIGLISSLSVYAEINDKGFIQTPYRVVENGQVTDKVVMLSAEDEE
ECCCCCCCCCCCCCCCCCEEECEEEEEEECCCCCEECCHHHHCCCCCCCEEEEEECCCCC
NKITVPVSIELDENNRIAAESVQARTKGDYPLVLAEEVNYMDVSPVQIVSAAAALIPFLE
CEEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHC
HDDGNRALMGANMQRQAVPLLVSEAPIVGTGMEAKVARDSRAVIVAEGPGVVQCVTADRI
CCCCCEEEECCCCCHHCCCEEEECCCEECCCCCCEECCCCCEEEEECCCCEEEEEECCEE
EVRYDLDPENNTVSLLDPDEGVKVYKLIKFKRSNQDTCISQRPLVHNGQRVNAGDVLADS
EEEEECCCCCCEEEEECCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECC
SSTDNGELALGKNVLVAFMPWRGYNFEDAIVLSERLVYDDVFTSIHVHEFESSVRDTKRG
CCCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGKITPKGESDPTPEEKLLRAIF
HHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
GDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKIGMDVKERMEAIDKQFDLKEADLRSRF
CCCCCCCCCCCEECCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
AKWMKQYLNGKKSVAITSDKGKVLVPEGTVIDEALLAKFNGLPFLESIDLSKGIVSGAKT
HHHHHHHHCCCCEEEEECCCCCEECCCCCHHHHHHHHHHCCCCCHHHCCCHHHHHCCCCC
NENVVRLIREYRLKLKDLSDERENEKYKINVGDELPPGIEELAKVYIAQKRKIQVGDKMA
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCEEECCCHHC
GRHGNKGVVGKILPIEDMPFMEDGTPVDIVLNPLGVPSRMNIGQLYETSLGWAGKKLGVK
CCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCHHCCEE
FKTPIFSGATYTEVQEYLEKAGLPGHGKVKLFDGRTGEQFHDEVTVGYIYMLKLSHLVDD
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHCC
KIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGR
CHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCC
NKTYEAIVKGQNLPEPGTPESFNVLIRELQGLGLEIRIDDRVP
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MKVADATPTPCIDFSKIQSIINPPDLLKVQLDSFHNFIQDSVPLEKRKDQGLEKVLRSAF
CCCCCCCCCCCCCHHHHHHHCCCCHHEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PITDTRGLYLLEYISYSFDKPKYTVEECIERGLTYDVSLKIKLKLSYKDEADEPDWKETI
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCHHHHHH
QQEVYLGRIPYMTDRGTFIINGAERVVVAQLHRSPGVVFSEAVHPNGKKMYSAKIVPTRG
HHHHHHCCCCEEECCCEEEECCCCEEEEEEHHCCCCCEEECCCCCCCCEEEEEEEEECCC
SWIEFQTDINNQIFVYIDQKKNFLVTALLRAIGFAKDEDILGLFDLVEEVEVSSKSSKRE
CEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHH
QLLGQYLASDIIDMTTGEVVPARAAITEEIIDQIVAAGYKTVKVMKTTSPEKGVDKSVII
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHH
NTILNDSSATEEEALEIVYEELRSNEAPDIDAARSFLERTFFNQKKYDLGDVGRYRIQKK
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LQNELAELSAYLEKRPELKELSDAIYERILQTISTYSEEPIGEDILVLTHYDIIAVINYL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
IKLINGMAEVDDVDHLANRRVRSVGEQLAAQFVIGLARMGKNVREKLNSRDTDKIAPADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHH
INARTVSSVVSSFFATSQLSQFMDQTNPLAEMTNKRRVSALGPGGLTRERAGFEVRDVHY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCHHHCCCEEEEEEE
THYGRLCPIETPEGPNIGLISSLSVYAEINDKGFIQTPYRVVENGQVTDKVVMLSAEDEE
ECCCCCCCCCCCCCCCCCEEECEEEEEEECCCCCEECCHHHHCCCCCCCEEEEEECCCCC
NKITVPVSIELDENNRIAAESVQARTKGDYPLVLAEEVNYMDVSPVQIVSAAAALIPFLE
CEEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHC
HDDGNRALMGANMQRQAVPLLVSEAPIVGTGMEAKVARDSRAVIVAEGPGVVQCVTADRI
CCCCCEEEECCCCCHHCCCEEEECCCEECCCCCCEECCCCCEEEEECCCCEEEEEECCEE
EVRYDLDPENNTVSLLDPDEGVKVYKLIKFKRSNQDTCISQRPLVHNGQRVNAGDVLADS
EEEEECCCCCCEEEEECCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECC
SSTDNGELALGKNVLVAFMPWRGYNFEDAIVLSERLVYDDVFTSIHVHEFESSVRDTKRG
CCCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEQFTRDIYNVSEDALRNLDENGIVRIGAEVKERDILVGKITPKGESDPTPEEKLLRAIF
HHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
GDKSSDVKDASMHVPAGMKGIVIKTKLFSRKKKIGMDVKERMEAIDKQFDLKEADLRSRF
CCCCCCCCCCCEECCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
AKWMKQYLNGKKSVAITSDKGKVLVPEGTVIDEALLAKFNGLPFLESIDLSKGIVSGAKT
HHHHHHHHCCCCEEEEECCCCCEECCCCCHHHHHHHHHHCCCCCHHHCCCHHHHHCCCCC
NENVVRLIREYRLKLKDLSDERENEKYKINVGDELPPGIEELAKVYIAQKRKIQVGDKMA
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCEEECCCHHC
GRHGNKGVVGKILPIEDMPFMEDGTPVDIVLNPLGVPSRMNIGQLYETSLGWAGKKLGVK
CCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCHHCCEE
FKTPIFSGATYTEVQEYLEKAGLPGHGKVKLFDGRTGEQFHDEVTVGYIYMLKLSHLVDD
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHCC
KIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAANILREMLTVKSDDVIGR
CHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCC
NKTYEAIVKGQNLPEPGTPESFNVLIRELQGLGLEIRIDDRVP
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901