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The map label for this gene is 21672957

Identifier: 21672957

GI number: 21672957

Start: 110652

End: 111848

Strand: Reverse

Name: 21672957

Synonym: CT0116

Alternate gene names: NA

Gene position: 111848-110652 (Counterclockwise)

Preceding gene: 21672961

Following gene: 21672956

Centisome position: 5.19

GC content: 56.73

Gene sequence:

>1197_bases
ATGAGAAACATCGTGTTTACGGGCAAGGGGGGCGTCGGCAAAACCTCCATCGCGGCGTCGACCGCCGTCAGAGCCGCGGC
TCTCGGCTACAAAACGCTGGTCATCTCGACCGATCCCGCCCACAGCCTCGGCGACTCCTTCGACATCGAACTCGGCCCAT
CGCCGGTGAAGGTGGCCGAAAATCTCTGGGGCCAGGAGGTGAGCGTTTACGGCGATCTGTCGCTCAACTGGGAGGTGGTG
CGCGAACACTTCGCCCACCTGATGGAGGTGCAGGGCATCGAGGGAATTTACGTCGAGGAGATGGGCGTTCTGCCGGGCAT
GGAGGAGCTTTTCTCGCTCTCCTACATCAAGCGCTACAACGAGTCCAGCGAGTATGACCTGCTCGTGGTTGACTGTGCGC
CAACCGGCGAAACCTTGCGCCTGCTCTCCATTCCGGAAACCTTCGGCTGGATGCTCAAGCTGATGCGCAACATGGAGAAG
TACGTCGTCAAGCCGGTCATCAGGCCGCTCTCCAAACGCATCAGCCGCCTGCACGACTTCGTGCCCGACACCGACGTCTA
TGACCAGGTCGATCACCTCTTTTCGTCGGTCGAAGGGATCATCGAACTCCTGTCGGACAACTCGAAAACCACCGTGCGAC
TTGTCATGAATCCGGAGAAAATGGTCGTCAAGGAGTCGATGCGGGCACTCACCTACCTCAATCTGTACAACATCACGATT
GATCAGATCGTCATCAACCGCGTTTACATGGACGACGTTGACGGCCAGTATTTCAAAGGGTGGAAAGAGATTCAGAAAAA
ATACATCGCAGAGATCGAATCCTCTTTCGGGCCGATTCCCATCACCCGGGTGCCGCTCTTCCGCACCGAGGTGCTCGGTC
TTGAGATGCTTAAAAAGGTGGGCGAAACAGTTTACGGCGACCGCAACCCGCTCGACATCTTCTACCACGAAGAGCATACA
GAGATCGTCAAGCCCGGCGAAGGGCATTACGTCATGAAGCTGCGCCTGCCCTTTGTCTTTGACAACCGCATGGAAGCCAA
CATCGTGCAGGTCGGCGACTTGCTGACGATCAGAATCGGCAACCACCAGAAAAGTGTCGTCCTCCCAACCTTCCTGGCCG
GCATGAAAGTCACCCACGCCGGATACGAGGAAAAATGGCTGGCAATCGAGTTCAGGAAGAAGGAGACGGCAAAATGA

Upstream 100 bases:

>100_bases
TGCGGCCCACTTGCTTTCCACAGAAATTATCAGCTCCCCGAATCGGTTGTAAAAGGTTACGACCGCACATTGGCAAAAAA
ATTCCCTCACAGGAGGCAGC

Downstream 100 bases:

>100_bases
GTTAAAGGAATCGCCATTCCCGAAATTCACAACACTCGCAGGGCGAACAAAAGAGGATCGCCCTGACCATTCTCATGGAG
TCAAACCGAACGAGCCTTCA

Product: ArsA ATPase family protein

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRNIVFTGKGGVGKTSIAASTAVRAAALGYKTLVISTDPAHSLGDSFDIELGPSPVKVAENLWGQEVSVYGDLSLNWEVV
REHFAHLMEVQGIEGIYVEEMGVLPGMEELFSLSYIKRYNESSEYDLLVVDCAPTGETLRLLSIPETFGWMLKLMRNMEK
YVVKPVIRPLSKRISRLHDFVPDTDVYDQVDHLFSSVEGIIELLSDNSKTTVRLVMNPEKMVVKESMRALTYLNLYNITI
DQIVINRVYMDDVDGQYFKGWKEIQKKYIAEIESSFGPIPITRVPLFRTEVLGLEMLKKVGETVYGDRNPLDIFYHEEHT
EIVKPGEGHYVMKLRLPFVFDNRMEANIVQVGDLLTIRIGNHQKSVVLPTFLAGMKVTHAGYEEKWLAIEFRKKETAK

Sequences:

>Translated_398_residues
MRNIVFTGKGGVGKTSIAASTAVRAAALGYKTLVISTDPAHSLGDSFDIELGPSPVKVAENLWGQEVSVYGDLSLNWEVV
REHFAHLMEVQGIEGIYVEEMGVLPGMEELFSLSYIKRYNESSEYDLLVVDCAPTGETLRLLSIPETFGWMLKLMRNMEK
YVVKPVIRPLSKRISRLHDFVPDTDVYDQVDHLFSSVEGIIELLSDNSKTTVRLVMNPEKMVVKESMRALTYLNLYNITI
DQIVINRVYMDDVDGQYFKGWKEIQKKYIAEIESSFGPIPITRVPLFRTEVLGLEMLKKVGETVYGDRNPLDIFYHEEHT
EIVKPGEGHYVMKLRLPFVFDNRMEANIVQVGDLLTIRIGNHQKSVVLPTFLAGMKVTHAGYEEKWLAIEFRKKETAK
>Mature_398_residues
MRNIVFTGKGGVGKTSIAASTAVRAAALGYKTLVISTDPAHSLGDSFDIELGPSPVKVAENLWGQEVSVYGDLSLNWEVV
REHFAHLMEVQGIEGIYVEEMGVLPGMEELFSLSYIKRYNESSEYDLLVVDCAPTGETLRLLSIPETFGWMLKLMRNMEK
YVVKPVIRPLSKRISRLHDFVPDTDVYDQVDHLFSSVEGIIELLSDNSKTTVRLVMNPEKMVVKESMRALTYLNLYNITI
DQIVINRVYMDDVDGQYFKGWKEIQKKYIAEIESSFGPIPITRVPLFRTEVLGLEMLKKVGETVYGDRNPLDIFYHEEHT
EIVKPGEGHYVMKLRLPFVFDNRMEANIVQVGDLLTIRIGNHQKSVVLPTFLAGMKVTHAGYEEKWLAIEFRKKETAK

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=282, Percent_Identity=26.9503546099291, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17557003, Length=301, Percent_Identity=24.2524916943522, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320103, Length=303, Percent_Identity=27.3927392739274, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586297, Length=306, Percent_Identity=27.4509803921569, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 45233; Mature: 45233

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIVFTGKGGVGKTSIAASTAVRAAALGYKTLVISTDPAHSLGDSFDIELGPSPVKVAE
CCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHCCCCEEEEECCCHHHHHH
NLWGQEVSVYGDLSLNWEVVREHFAHLMEVQGIEGIYVEEMGVLPGMEELFSLSYIKRYN
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCC
ESSEYDLLVVDCAPTGETLRLLSIPETFGWMLKLMRNMEKYVVKPVIRPLSKRISRLHDF
CCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPDTDVYDQVDHLFSSVEGIIELLSDNSKTTVRLVMNPEKMVVKESMRALTYLNLYNITI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHEEH
DQIVINRVYMDDVDGQYFKGWKEIQKKYIAEIESSFGPIPITRVPLFRTEVLGLEMLKKV
HHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHH
GETVYGDRNPLDIFYHEEHTEIVKPGEGHYVMKLRLPFVFDNRMEANIVQVGDLLTIRIG
HHHHCCCCCCEEEEEECCCCCEECCCCCCEEEEEECCEEECCCCCCCEEEECCEEEEEEC
NHQKSVVLPTFLAGMKVTHAGYEEKWLAIEFRKKETAK
CCCCCEEHHHHHHCCEEECCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRNIVFTGKGGVGKTSIAASTAVRAAALGYKTLVISTDPAHSLGDSFDIELGPSPVKVAE
CCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHCCCCEEEEECCCHHHHHH
NLWGQEVSVYGDLSLNWEVVREHFAHLMEVQGIEGIYVEEMGVLPGMEELFSLSYIKRYN
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCC
ESSEYDLLVVDCAPTGETLRLLSIPETFGWMLKLMRNMEKYVVKPVIRPLSKRISRLHDF
CCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPDTDVYDQVDHLFSSVEGIIELLSDNSKTTVRLVMNPEKMVVKESMRALTYLNLYNITI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHEEH
DQIVINRVYMDDVDGQYFKGWKEIQKKYIAEIESSFGPIPITRVPLFRTEVLGLEMLKKV
HHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHH
GETVYGDRNPLDIFYHEEHTEIVKPGEGHYVMKLRLPFVFDNRMEANIVQVGDLLTIRIG
HHHHCCCCCCEEEEEECCCCCEECCCCCCEEEEEECCEEECCCCCCCEEEECCEEEEEEC
NHQKSVVLPTFLAGMKVTHAGYEEKWLAIEFRKKETAK
CCCCCEEHHHHHHCCEEECCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]