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The map label for this gene is aroB [H]

Identifier: 21672940

GI number: 21672940

Start: 92946

End: 93938

Strand: Direct

Name: aroB [H]

Synonym: CT0099

Alternate gene names: 21672940

Gene position: 92946-93938 (Clockwise)

Preceding gene: 21672939

Following gene: 21672942

Centisome position: 4.31

GC content: 62.74

Gene sequence:

>993_bases
ATGCAAGGTCGGGTTCTCGCTAATAATTGTAAAACCATGTCCAACGCAACCGAACGCATTGCCTGCATCGATGTCGGCAC
CAATACGGCCCTGCTGCTGGTCGCCGATCTTGACGCTGCGGCCAGCAACATCGTGACCGTCGATCACCGCCAGACCATCG
TGCGCCTCGGCCAGAACGTCGATGAATACCGGATGATCCACCCTGAAGCGCTCGACCGGCTGATTGCCTGCATGACGGAG
TACCGGAATCTGTGCGATGGACTTGGCGTGCAGCGGATTCTGGCCGTCGGTACCAGCGCCCTGCGTGACGCGGCCAACCG
CGATGAAGTCATCGCGGCGGTCAAGGGCGAGACCGGCATCGAAATCCGCTGCATCAGCGGAGACGAGGAGGCCGCGCTCA
CCTTTTTCGGCGCGGTGGCCGGGCTGCCGGAGGTGCCGGAACCGTTCACGGTGATCGACATCGGCGGTGGCAGCACCGAA
ATCATCATGGGCACAGTCGAGCAGGTTGACAGCGCGGTCAGCATAAACATCGGTTCGGTGAGAATGACCGAACGCTTTTG
CGCCGCGCAGCCCCCGTCGCCGGAGGCGTTCGAGGCGGCAAAAAAGGAGATTAACCGCAAGCTCGCCAGAAGCCTGCCGC
CGTTTTTCGCGGGTCGCCAGCAGGTTTTCGGCGTCGCGGGCACGCTGACCACCATTGCACAGGTGTGCCTCGGTGACCGC
CATTTCGACGCGGCGAAAGTGCAGGGCTACCGGCTTGAATACGATGCGGTGCACGAGCTGCTCGACCGGCTCCGCGCGAT
GAAGCTCAACGAGATCGTGGCGCTCGGCATCCCAGAAGGGCGCGCCGACGTCTTTACGATGGGCGTGCTCATCCTGCATC
AGTTCATGCGGATGCTCGGCGTCGGCAGCCTGACGGTGAGCATCCAGGGCCTGCGCTACGGCGTGGCGCAGCAGGAGCTT
CAGAAGCTTCTGATGCTTCGCAACCGGACCTGA

Upstream 100 bases:

>100_bases
TTCAGAATCAGGGGAGCGAACTCTGCCCCGCCCCGGCTTGAAAGCCGAGGCAACATGAATGCAAGAGATTTGAAGGGCCA
CGGGGCTGAAGCTCTGCTGA

Downstream 100 bases:

>100_bases
AGCTCACGGCTTTCTGCACGAGAGCCAGATGAGACTGCCCGTAGCGTTTTTCGTGAAAAAGAGATAGCGCTCGCTGCTCT
CCCCGATTTTGTACCGCTTG

Product: exopolyphosphatase, putative

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQGRVLANNCKTMSNATERIACIDVGTNTALLLVADLDAAASNIVTVDHRQTIVRLGQNVDEYRMIHPEALDRLIACMTE
YRNLCDGLGVQRILAVGTSALRDAANRDEVIAAVKGETGIEIRCISGDEEAALTFFGAVAGLPEVPEPFTVIDIGGGSTE
IIMGTVEQVDSAVSINIGSVRMTERFCAAQPPSPEAFEAAKKEINRKLARSLPPFFAGRQQVFGVAGTLTTIAQVCLGDR
HFDAAKVQGYRLEYDAVHELLDRLRAMKLNEIVALGIPEGRADVFTMGVLILHQFMRMLGVGSLTVSIQGLRYGVAQQEL
QKLLMLRNRT

Sequences:

>Translated_330_residues
MQGRVLANNCKTMSNATERIACIDVGTNTALLLVADLDAAASNIVTVDHRQTIVRLGQNVDEYRMIHPEALDRLIACMTE
YRNLCDGLGVQRILAVGTSALRDAANRDEVIAAVKGETGIEIRCISGDEEAALTFFGAVAGLPEVPEPFTVIDIGGGSTE
IIMGTVEQVDSAVSINIGSVRMTERFCAAQPPSPEAFEAAKKEINRKLARSLPPFFAGRQQVFGVAGTLTTIAQVCLGDR
HFDAAKVQGYRLEYDAVHELLDRLRAMKLNEIVALGIPEGRADVFTMGVLILHQFMRMLGVGSLTVSIQGLRYGVAQQEL
QKLLMLRNRT
>Mature_330_residues
MQGRVLANNCKTMSNATERIACIDVGTNTALLLVADLDAAASNIVTVDHRQTIVRLGQNVDEYRMIHPEALDRLIACMTE
YRNLCDGLGVQRILAVGTSALRDAANRDEVIAAVKGETGIEIRCISGDEEAALTFFGAVAGLPEVPEPFTVIDIGGGSTE
IIMGTVEQVDSAVSINIGSVRMTERFCAAQPPSPEAFEAAKKEINRKLARSLPPFFAGRQQVFGVAGTLTTIAQVCLGDR
HFDAAKVQGYRLEYDAVHELLDRLRAMKLNEIVALGIPEGRADVFTMGVLILHQFMRMLGVGSLTVSIQGLRYGVAQQEL
QKLLMLRNRT

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=309, Percent_Identity=29.126213592233, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788848, Length=304, Percent_Identity=27.9605263157895, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 35800; Mature: 35800

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGRVLANNCKTMSNATERIACIDVGTNTALLLVADLDAAASNIVTVDHRQTIVRLGQNV
CCCCEECCCCHHHHCHHHEEEEEEECCCCEEEEEEECCCCCCCCEEECHHHHHHHHCCCC
DEYRMIHPEALDRLIACMTEYRNLCDGLGVQRILAVGTSALRDAANRDEVIAAVKGETGI
HHHHEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCE
EIRCISGDEEAALTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTVEQVDSAVSINIGSV
EEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEHHHHCCEEEEEECCE
RMTERFCAAQPPSPEAFEAAKKEINRKLARSLPPFFAGRQQVFGVAGTLTTIAQVCLGDR
EHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHCCC
HFDAAKVQGYRLEYDAVHELLDRLRAMKLNEIVALGIPEGRADVFTMGVLILHQFMRMLG
CCCHHHCCCEEECHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHC
VGSLTVSIQGLRYGVAQQELQKLLMLRNRT
CCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGRVLANNCKTMSNATERIACIDVGTNTALLLVADLDAAASNIVTVDHRQTIVRLGQNV
CCCCEECCCCHHHHCHHHEEEEEEECCCCEEEEEEECCCCCCCCEEECHHHHHHHHCCCC
DEYRMIHPEALDRLIACMTEYRNLCDGLGVQRILAVGTSALRDAANRDEVIAAVKGETGI
HHHHEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCE
EIRCISGDEEAALTFFGAVAGLPEVPEPFTVIDIGGGSTEIIMGTVEQVDSAVSINIGSV
EEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEHHHHCCEEEEEECCE
RMTERFCAAQPPSPEAFEAAKKEINRKLARSLPPFFAGRQQVFGVAGTLTTIAQVCLGDR
EHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHCCC
HFDAAKVQGYRLEYDAVHELLDRLRAMKLNEIVALGIPEGRADVFTMGVLILHQFMRMLG
CCCHHHCCCEEECHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHC
VGSLTVSIQGLRYGVAQQELQKLLMLRNRT
CCCEEEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]