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The map label for this gene is 21672911

Identifier: 21672911

GI number: 21672911

Start: 68965

End: 70104

Strand: Direct

Name: 21672911

Synonym: CT0070

Alternate gene names: NA

Gene position: 68965-70104 (Clockwise)

Preceding gene: 21672909

Following gene: 21672912

Centisome position: 3.2

GC content: 60.96

Gene sequence:

>1140_bases
ATGAAAAAACGACTCTTCACCCCTGGACCGACGCCGGTACCGGAAAACGTCATGCTTCGCATGGCCGCGCCAATCATCCA
TCACCGGAATCCTGAATTTATGGAGATTCTGGAGCGGGTGCACGAAAACCTCAAGTATCTGTTTAGAACAACCCAGCCGG
TGGTGGTTATGACCTGTTCGGGCACCGGCGGCATGGAGGCGGCCATTTCGAGCCTGTTTCGGCAGGGCGACAAGCTTATC
ACGATCAATGGCGGCAAGTTCGGCGAACGGTGGAGCGAGCTGGCGCGCATCTACACGGGCAACTGCGTCGAGGAGAAGAT
CGAGTGGGGCACGGCCATTTCACCAGAACGAATCGCCGAACTGCTCGACGAGCATCCGGACGCGATGGGCGTCTGCATCA
CCCATTCGGAGACCTCCACCGGCACCGCATCTGACGTCAGGGCGTTGTGCGCGGCTATCCGTGAACGCTCCGAGGCGCTG
ATCCTTGTTGATGGTATCACCGCCATCGGCGCGCACGAGTTCCACTTCGATGACTGGGGCGCGGATATCTGCATCACCGG
CTCGCAGAAGGGGCTCATGATGCCGCCCGGCCTGGCGCTGGTGGCTGTCTCGGAGCGGGCGCAGGAGATCATCCACAACC
GCAAGCATCAGCCGCAGTATTACCTGAGCCTGCGCAAGGCGCTCAAATCCCATGCAGGCAACGACACGCCTTTCACTCCG
GCGGTTTCGCTTATCATCGGTCTCGACGAGGCGTTGCAGATGCTGCGCGCCGAGGGGATCGAAAATGTCTGGGCGCGCCA
CGAAGCGCTCGCGGGCGCATGCCGCCTCGGCTGCCAGGCGCTCGGCATGGAGCTGTTCAGTGAGTCGCCCTCGTACGCCG
TTACAGCGGTCTGGCTGCCCGAAGGCGCGGACTGGAAGGAGTTCAACACCACCCTGAAGATCAAAAACGGCATCACGGTT
GCCGCCGGGCAGGACGACTTCAAGGGCAGAATCTTCCGGATTTCGCACCTTGGTTATTACGATGAACTCGACATGCTGAC
CCTGATGGGCGGGCTTGAGCGGTCGCTCAAAATGATGGAGATTCCTTTCAGGGTTGGCGCTGGCGTCAGCGCCGTCCAGC
GGGCGTTTCTCGGGGAGTAG

Upstream 100 bases:

>100_bases
CTCAAATCGATCCTCGACCGCTGCATGAGTTGCGCCAGCGCCTGGTGGCGGCCGGTTTTCATCATCTAACAAAAGACGCC
GCTCAGGCAATGCTTGGTTC

Downstream 100 bases:

>100_bases
GGGCCGGTTGTTTTGCAGAATGGCCGGGCGAGGTTGATTATATTGGAGAAAATGCCGCCATGAAACGAGCACTGTTGTTA
CTGATCGCGCTCTTTTCCTT

Product: aminotransferase, class V

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILERVHENLKYLFRTTQPVVVMTCSGTGGMEAAISSLFRQGDKLI
TINGGKFGERWSELARIYTGNCVEEKIEWGTAISPERIAELLDEHPDAMGVCITHSETSTGTASDVRALCAAIRERSEAL
ILVDGITAIGAHEFHFDDWGADICITGSQKGLMMPPGLALVAVSERAQEIIHNRKHQPQYYLSLRKALKSHAGNDTPFTP
AVSLIIGLDEALQMLRAEGIENVWARHEALAGACRLGCQALGMELFSESPSYAVTAVWLPEGADWKEFNTTLKIKNGITV
AAGQDDFKGRIFRISHLGYYDELDMLTLMGGLERSLKMMEIPFRVGAGVSAVQRAFLGE

Sequences:

>Translated_379_residues
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILERVHENLKYLFRTTQPVVVMTCSGTGGMEAAISSLFRQGDKLI
TINGGKFGERWSELARIYTGNCVEEKIEWGTAISPERIAELLDEHPDAMGVCITHSETSTGTASDVRALCAAIRERSEAL
ILVDGITAIGAHEFHFDDWGADICITGSQKGLMMPPGLALVAVSERAQEIIHNRKHQPQYYLSLRKALKSHAGNDTPFTP
AVSLIIGLDEALQMLRAEGIENVWARHEALAGACRLGCQALGMELFSESPSYAVTAVWLPEGADWKEFNTTLKIKNGITV
AAGQDDFKGRIFRISHLGYYDELDMLTLMGGLERSLKMMEIPFRVGAGVSAVQRAFLGE
>Mature_379_residues
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILERVHENLKYLFRTTQPVVVMTCSGTGGMEAAISSLFRQGDKLI
TINGGKFGERWSELARIYTGNCVEEKIEWGTAISPERIAELLDEHPDAMGVCITHSETSTGTASDVRALCAAIRERSEAL
ILVDGITAIGAHEFHFDDWGADICITGSQKGLMMPPGLALVAVSERAQEIIHNRKHQPQYYLSLRKALKSHAGNDTPFTP
AVSLIIGLDEALQMLRAEGIENVWARHEALAGACRLGCQALGMELFSESPSYAVTAVWLPEGADWKEFNTTLKIKNGITV
AAGQDDFKGRIFRISHLGYYDELDMLTLMGGLERSLKMMEIPFRVGAGVSAVQRAFLGE

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=344, Percent_Identity=27.6162790697674, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17536281, Length=347, Percent_Identity=30.835734870317, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6321079, Length=358, Percent_Identity=30.1675977653631, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17530823, Length=346, Percent_Identity=30.3468208092486, Blast_Score=156, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41768; Mature: 41768

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILERVHENLKYLFRTTQPVVVMTCS
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GTGGMEAAISSLFRQGDKLITINGGKFGERWSELARIYTGNCVEEKIEWGTAISPERIAE
CCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHH
LLDEHPDAMGVCITHSETSTGTASDVRALCAAIRERSEALILVDGITAIGAHEFHFDDWG
HHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHCCCEEECCCCC
ADICITGSQKGLMMPPGLALVAVSERAQEIIHNRKHQPQYYLSLRKALKSHAGNDTPFTP
CCEEEECCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHH
AVSLIIGLDEALQMLRAEGIENVWARHEALAGACRLGCQALGMELFSESPSYAVTAVWLP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
EGADWKEFNTTLKIKNGITVAAGQDDFKGRIFRISHLGYYDELDMLTLMGGLERSLKMME
CCCCHHHHCCEEEEECCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
IPFRVGAGVSAVQRAFLGE
CCHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MKKRLFTPGPTPVPENVMLRMAAPIIHHRNPEFMEILERVHENLKYLFRTTQPVVVMTCS
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GTGGMEAAISSLFRQGDKLITINGGKFGERWSELARIYTGNCVEEKIEWGTAISPERIAE
CCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHH
LLDEHPDAMGVCITHSETSTGTASDVRALCAAIRERSEALILVDGITAIGAHEFHFDDWG
HHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHCCCEEECCCCC
ADICITGSQKGLMMPPGLALVAVSERAQEIIHNRKHQPQYYLSLRKALKSHAGNDTPFTP
CCEEEECCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHH
AVSLIIGLDEALQMLRAEGIENVWARHEALAGACRLGCQALGMELFSESPSYAVTAVWLP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
EGADWKEFNTTLKIKNGITVAAGQDDFKGRIFRISHLGYYDELDMLTLMGGLERSLKMME
CCCCHHHHCCEEEEECCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
IPFRVGAGVSAVQRAFLGE
CCHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]