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The map label for this gene is oxaA

Identifier: 21672847

GI number: 21672847

Start: 4268

End: 6040

Strand: Direct

Name: oxaA

Synonym: CT0006

Alternate gene names: 21672847

Gene position: 4268-6040 (Clockwise)

Preceding gene: 21672846

Following gene: 21672848

Centisome position: 0.2

GC content: 57.59

Gene sequence:

>1773_bases
ATGGACAGAAATTCGGTGATAGGCTTTGCCCTGATTGCTGCAATCATGATCGTATGGCTACAGTTCATGAAGCCTGAGCA
GAAGCTGGGACTCGAAAAAGCGGCGGCATCGCGAGAGGCGGTTCAGAAAACACCTGCGGCGGCATTGCCCGCCCCGTCGG
CGGCAGTGGCGGCTGCGGCCAGGGCTGACAGCCTCGGTTCCTTCGCCCAGGCCTCCGTCGGCACGGAAAAGACCATCACC
GTCAGCAACGATCTGTTCACGGCAACCCTCTCCTCGAAGGGCGCGACCCTGAAGTCGCTGGTGCTCAAAAAGCATCTCGA
TGGCAACCGCAAGCCCTTCAACCTGATCTCCGCCAGCGACAAGGGCGCGCTCTCCATGCTGTTCCTCAGCAGTGACGGCA
AGAAGATCGATACCCGCGATCTCTATTTCCGCAGCCTCGATGCCAAAACCACCGAAACCGTGACCGGCAAAGAGAAGCTG
TCCGTCAGTTATGTGCTCGATGTCGATGCCACGCGCAGCATCCAGATCACCTACACCTTCACGGGCGACAGCTACGTGGT
CGATTACGATCTGAAGCTCAACGGTTTCGGCTCGTCCATCGCCGGAAACGAGTACCAGCTCGACTGGGACGGCGGACTGA
ACTACTCGGAAAAAGACCAGGTTGACGAGTCGCACAACGCCATTGCCAGTGCCTACCTTGGTGGTAGCGTGGTCAAGCTC
GATGCCAAGGACGCCAAAAAAACCTGGCAGGATGAGGAGTCCGGCAAGGCGCAGTGGGTTGCCGTCAGGAACAAATATTT
TGTCGCGGCCATCATGCCGCAGCGCACCACCGATGGCATCTATCTGCACGGCACCAAAAAGGATGGCAGCGATTTCAAGA
ACTATGTCGCGGCGCTGAAAATGAGCTTCCCCGCCGGTCAGCAGAGCGTCGATGACCACTACCGTCTCTACGTCGGCCCG
CTCGACTACAACACGGTCAAGTCGCTGAACGCCGATCTCGAAAAGATCATGGACTTCGGCTGGGACTGGCTGACCCGTCC
CTTCGCCGAATACCTGATTCTGCCGATCTTCAACTGGATGAACAAATATGTGACCAACTACGGTCTTATCATCATCATCT
TCGCCTTCCTCATCAAGCTGGTCACCTGGCCGCTGTCGCTGGCCTCGACCAAGTCGATGAAGAAGATGTCGGCGCTTCAG
CCCGTGATGAAGGAGCTTCAGGAGAAGTACAAGGACAACCCGGCCAAGCTGCAAAGCGAACTCGGACGCATCTACAAGGA
AGCAGGCGTCAATCCGCTTGGCGGCTGCCTGCCGACGGTGATCCAGATGCCGCTGCTCTTCGCGATGTTCTACGTCTTCC
GCTCCTCGATCCAGCTTCGCCAGCACGGCTTCCTCTGGGTGAAGGATCTTTCCGTGCCCGACTCGGTGTACCATTTCGCC
TTCAAGCTGCCGCTCTACGGCGACCACATCGCGATCATGCCGATTTTGATGGCCGTGACCGTTTTCTTCCAGCAGAAGAT
CACGCCGAACGCCCAGTCAAACGAGCAGACGAAGATCATGATGTGGCTGTTCCCGGCCATGATGCTGTTCTTTTTCAACA
ACATGCCGGCGGGCCTGGCGCTCTACTATCTGATGTTCAACATCTTCAGCGTCGCCCAGCAGGCCTACATGAACGCCACC
ATCACCGACGAGGAGAAGGCTGCCGCCGCCATGCAGGTCGCCGCCGCCACCAAACCGGCTCAGTCTGCCAAAAAGGGAGG
GAAGAAAAAGTAA

Upstream 100 bases:

>100_bases
TCTGGAGGGTGCTTCGTTGCAATCCGTTTTCAAAAGGCGGCTATGATCCGGTACCGCCAAAATCAGTGAAATCCGCAGGT
AATTCAAAAGATTCGAAGTA

Downstream 100 bases:

>100_bases
CCCACGATGGGCGGTCTCGAACAGGCGGATGCTCGGCTTTTCCAGCTCCTGAACCATAGCTTGGCCACTCCGGCGCTGGA
CGACCTGATGCCGTTTCTGA

Product: Oxa1/60 kDa IMP family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MDRNSVIGFALIAAIMIVWLQFMKPEQKLGLEKAAASREAVQKTPAAALPAPSAAVAAAARADSLGSFAQASVGTEKTIT
VSNDLFTATLSSKGATLKSLVLKKHLDGNRKPFNLISASDKGALSMLFLSSDGKKIDTRDLYFRSLDAKTTETVTGKEKL
SVSYVLDVDATRSIQITYTFTGDSYVVDYDLKLNGFGSSIAGNEYQLDWDGGLNYSEKDQVDESHNAIASAYLGGSVVKL
DAKDAKKTWQDEESGKAQWVAVRNKYFVAAIMPQRTTDGIYLHGTKKDGSDFKNYVAALKMSFPAGQQSVDDHYRLYVGP
LDYNTVKSLNADLEKIMDFGWDWLTRPFAEYLILPIFNWMNKYVTNYGLIIIIFAFLIKLVTWPLSLASTKSMKKMSALQ
PVMKELQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPTVIQMPLLFAMFYVFRSSIQLRQHGFLWVKDLSVPDSVYHFA
FKLPLYGDHIAIMPILMAVTVFFQQKITPNAQSNEQTKIMMWLFPAMMLFFFNNMPAGLALYYLMFNIFSVAQQAYMNAT
ITDEEKAAAAMQVAAATKPAQSAKKGGKKK

Sequences:

>Translated_590_residues
MDRNSVIGFALIAAIMIVWLQFMKPEQKLGLEKAAASREAVQKTPAAALPAPSAAVAAAARADSLGSFAQASVGTEKTIT
VSNDLFTATLSSKGATLKSLVLKKHLDGNRKPFNLISASDKGALSMLFLSSDGKKIDTRDLYFRSLDAKTTETVTGKEKL
SVSYVLDVDATRSIQITYTFTGDSYVVDYDLKLNGFGSSIAGNEYQLDWDGGLNYSEKDQVDESHNAIASAYLGGSVVKL
DAKDAKKTWQDEESGKAQWVAVRNKYFVAAIMPQRTTDGIYLHGTKKDGSDFKNYVAALKMSFPAGQQSVDDHYRLYVGP
LDYNTVKSLNADLEKIMDFGWDWLTRPFAEYLILPIFNWMNKYVTNYGLIIIIFAFLIKLVTWPLSLASTKSMKKMSALQ
PVMKELQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPTVIQMPLLFAMFYVFRSSIQLRQHGFLWVKDLSVPDSVYHFA
FKLPLYGDHIAIMPILMAVTVFFQQKITPNAQSNEQTKIMMWLFPAMMLFFFNNMPAGLALYYLMFNIFSVAQQAYMNAT
ITDEEKAAAAMQVAAATKPAQSAKKGGKKK
>Mature_590_residues
MDRNSVIGFALIAAIMIVWLQFMKPEQKLGLEKAAASREAVQKTPAAALPAPSAAVAAAARADSLGSFAQASVGTEKTIT
VSNDLFTATLSSKGATLKSLVLKKHLDGNRKPFNLISASDKGALSMLFLSSDGKKIDTRDLYFRSLDAKTTETVTGKEKL
SVSYVLDVDATRSIQITYTFTGDSYVVDYDLKLNGFGSSIAGNEYQLDWDGGLNYSEKDQVDESHNAIASAYLGGSVVKL
DAKDAKKTWQDEESGKAQWVAVRNKYFVAAIMPQRTTDGIYLHGTKKDGSDFKNYVAALKMSFPAGQQSVDDHYRLYVGP
LDYNTVKSLNADLEKIMDFGWDWLTRPFAEYLILPIFNWMNKYVTNYGLIIIIFAFLIKLVTWPLSLASTKSMKKMSALQ
PVMKELQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPTVIQMPLLFAMFYVFRSSIQLRQHGFLWVKDLSVPDSVYHFA
FKLPLYGDHIAIMPILMAVTVFFQQKITPNAQSNEQTKIMMWLFPAMMLFFFNNMPAGLALYYLMFNIFSVAQQAYMNAT
ITDEEKAAAAMQVAAATKPAQSAKKGGKKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=506, Percent_Identity=27.4703557312253, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_CHLTE (Q8KGG2)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_660912.1
- ProteinModelPortal:   Q8KGG2
- GeneID:   1006144
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0006
- NMPDR:   fig|194439.1.peg.6
- TIGR:   CT0006
- HOGENOM:   HBG405598
- OMA:   YVFRSSI
- ProtClustDB:   CLSK637099
- BioCyc:   CTEP194439:CT_0006-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 65490; Mature: 65490

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xbcfae04)-; HASH(0xbd002a8)-; HASH(0xbcfaca8)-; HASH(0xbcfe57c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRNSVIGFALIAAIMIVWLQFMKPEQKLGLEKAAASREAVQKTPAAALPAPSAAVAAAA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RADSLGSFAQASVGTEKTITVSNDLFTATLSSKGATLKSLVLKKHLDGNRKPFNLISASD
HHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCC
KGALSMLFLSSDGKKIDTRDLYFRSLDAKTTETVTGKEKLSVSYVLDVDATRSIQITYTF
CCCEEEEEECCCCCCCCCHHHHHEECCCCCCCCCCCCHHEEEEEEEECCCCCEEEEEEEE
TGDSYVVDYDLKLNGFGSSIAGNEYQLDWDGGLNYSEKDQVDESHNAIASAYLGGSVVKL
CCCCEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEE
DAKDAKKTWQDEESGKAQWVAVRNKYFVAAIMPQRTTDGIYLHGTKKDGSDFKNYVAALK
CCHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHH
MSFPAGQQSVDDHYRLYVGPLDYNTVKSLNADLEKIMDFGWDWLTRPFAEYLILPIFNWM
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NKYVTNYGLIIIIFAFLIKLVTWPLSLASTKSMKKMSALQPVMKELQEKYKDNPAKLQSE
HHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGRIYKEAGVNPLGGCLPTVIQMPLLFAMFYVFRSSIQLRQHGFLWVKDLSVPDSVYHFA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHEE
FKLPLYGDHIAIMPILMAVTVFFQQKITPNAQSNEQTKIMMWLFPAMMLFFFNNMPAGLA
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
LYYLMFNIFSVAQQAYMNATITDEEKAAAAMQVAAATKPAQSAKKGGKKK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCH
>Mature Secondary Structure
MDRNSVIGFALIAAIMIVWLQFMKPEQKLGLEKAAASREAVQKTPAAALPAPSAAVAAAA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RADSLGSFAQASVGTEKTITVSNDLFTATLSSKGATLKSLVLKKHLDGNRKPFNLISASD
HHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCC
KGALSMLFLSSDGKKIDTRDLYFRSLDAKTTETVTGKEKLSVSYVLDVDATRSIQITYTF
CCCEEEEEECCCCCCCCCHHHHHEECCCCCCCCCCCCHHEEEEEEEECCCCCEEEEEEEE
TGDSYVVDYDLKLNGFGSSIAGNEYQLDWDGGLNYSEKDQVDESHNAIASAYLGGSVVKL
CCCCEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEE
DAKDAKKTWQDEESGKAQWVAVRNKYFVAAIMPQRTTDGIYLHGTKKDGSDFKNYVAALK
CCHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHH
MSFPAGQQSVDDHYRLYVGPLDYNTVKSLNADLEKIMDFGWDWLTRPFAEYLILPIFNWM
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NKYVTNYGLIIIIFAFLIKLVTWPLSLASTKSMKKMSALQPVMKELQEKYKDNPAKLQSE
HHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGRIYKEAGVNPLGGCLPTVIQMPLLFAMFYVFRSSIQLRQHGFLWVKDLSVPDSVYHFA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHEE
FKLPLYGDHIAIMPILMAVTVFFQQKITPNAQSNEQTKIMMWLFPAMMLFFFNNMPAGLA
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
LYYLMFNIFSVAQQAYMNATITDEEKAAAAMQVAAATKPAQSAKKGGKKK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901