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The map label for this gene is rnpA

Identifier: 21672845

GI number: 21672845

Start: 3494

End: 3958

Strand: Direct

Name: rnpA

Synonym: CT0004

Alternate gene names: 21672845

Gene position: 3494-3958 (Clockwise)

Preceding gene: 21672844

Following gene: 21672846

Centisome position: 0.16

GC content: 54.62

Gene sequence:

>465_bases
GTGTATCCGGGCATGCTTTCTGAAAAACGAACCAATGCCCTGCCAAGGGGAGAAATAGCCCGGGGAAAAAGCGCTGTTTC
CCGTCTGTTTAGCCAGGGTGGCCGTCTAAAGGGCGGTTTTCTCCTGTTGATCTATTCTGCTTCACGGCCGGTTGAGCAGG
CACCCCGGATACCAGTGAGGGTGCTGTTCACGGTTGGCAAAAAGCTGGTTCCGAGAGCCGTTGACCGCAACCGGATCAAA
CGACTGATGCGTGAGGCTTACCGGCTCGAAAAAAATATTTTGACCAGAGCGCTTGCATTCGACGCCGGCAAAGGCGATCA
TCAGGTGATGCTGGCGTTTTTATACCGGGCTCGGGCCGATGCCATTCCATCGCTTGAGCGGTTCCGGGCTGAAATTCGGC
ACATGCTGAAAAATCTTCTATCGAACAGGCTGCCGCAAACGCGGGAGGGTGACAGGATTGAGTAA

Upstream 100 bases:

>100_bases
AGGGCCGTCACTCCCTGAGTGTCAGCAGCTCGATGAGTGCTTCGAAACGTTAACTCACTGGCCGGAACGGGGCTTCGGTT
TCACTTCCGGGCGGATTTGC

Downstream 100 bases:

>100_bases
TACGGGCAATCAACAGCATCACGGGACGGAACACAACGGCAAAACCCCTGGCCAGCTGTTGAACATCGTGCCGATTCTCC
TGATACGATTTTACCAGTCA

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MYPGMLSEKRTNALPRGEIARGKSAVSRLFSQGGRLKGGFLLLIYSASRPVEQAPRIPVRVLFTVGKKLVPRAVDRNRIK
RLMREAYRLEKNILTRALAFDAGKGDHQVMLAFLYRARADAIPSLERFRAEIRHMLKNLLSNRLPQTREGDRIE

Sequences:

>Translated_154_residues
MYPGMLSEKRTNALPRGEIARGKSAVSRLFSQGGRLKGGFLLLIYSASRPVEQAPRIPVRVLFTVGKKLVPRAVDRNRIK
RLMREAYRLEKNILTRALAFDAGKGDHQVMLAFLYRARADAIPSLERFRAEIRHMLKNLLSNRLPQTREGDRIE
>Mature_154_residues
MYPGMLSEKRTNALPRGEIARGKSAVSRLFSQGGRLKGGFLLLIYSASRPVEQAPRIPVRVLFTVGKKLVPRAVDRNRIK
RLMREAYRLEKNILTRALAFDAGKGDHQVMLAFLYRARADAIPSLERFRAEIRHMLKNLLSNRLPQTREGDRIE

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_CHLTE (Q8KGG4)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_660910.1
- ProteinModelPortal:   Q8KGG4
- SMR:   Q8KGG4
- GeneID:   1006128
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0004
- NMPDR:   fig|194439.1.peg.4
- TIGR:   CT0004
- HOGENOM:   HBG405599
- OMA:   KHEILRK
- ProtClustDB:   PRK01903
- BioCyc:   CTEP194439:CT_0004-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 17584; Mature: 17584

Theoretical pI: Translated: 11.91; Mature: 11.91

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPGMLSEKRTNALPRGEIARGKSAVSRLFSQGGRLKGGFLLLIYSASRPVEQAPRIPVR
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHCCCCCHH
VLFTVGKKLVPRAVDRNRIKRLMREAYRLEKNILTRALAFDAGKGDHQVMLAFLYRARAD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AIPSLERFRAEIRHMLKNLLSNRLPQTREGDRIE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MYPGMLSEKRTNALPRGEIARGKSAVSRLFSQGGRLKGGFLLLIYSASRPVEQAPRIPVR
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHCCCCCHH
VLFTVGKKLVPRAVDRNRIKRLMREAYRLEKNILTRALAFDAGKGDHQVMLAFLYRARAD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AIPSLERFRAEIRHMLKNLLSNRLPQTREGDRIE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901