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The map label for this gene is fusA [H]

Identifier: 21672773

GI number: 21672773

Start: 562570

End: 564678

Strand: Reverse

Name: fusA [H]

Synonym: BUsg508

Alternate gene names: 21672773

Gene position: 564678-562570 (Counterclockwise)

Preceding gene: 21672774

Following gene: 21672772

Centisome position: 88.03

GC content: 32.34

Gene sequence:

>2109_bases
ATGTCTCGTACAACACCTATTTGTCAATATCGTAACATTGGTATCAGTGCCCATATAGATGCAGGGAAGACAACCACAAC
TGAAAGAATCTTATTTTATACTGGTATTAATCATAAAATTGGTGAAGTTCACGATGGTGCTGCTACCATGGATTGGATGG
AACAAGAACAAGAAAGAGGAATTACTATTACCTCTGCTGCTACTACTGCATTTTGGAGTGGTATGGCTAAGCAATTTAAA
CCTCACAGAATTAATATTATTGATACACCTGGACATGTTGATTTTACTATAGAAGTTGAACGTTCAATGCGTGTATTAGA
TGGTGCTGTTATGGTTTATTGCGCAGTTGGAGGTGTTCAACCTCAATCAGAAACTGTATGGCGACAAGCAAATAAATACA
ATGTTCCTCGTATAGCTTTTATAAATAAAATGGATCGTATGGGAGCAAATTTTTTAAGATCAGTAAAACAAATTAAAACA
CGATTAGGAGGCAATCCTGTACCACTTCAGCTACCTATTGGATCAGAAGAAAATTTTAAAGGAGTTATAGATTTAATAAA
AATGAAAGCCATTAAATGGAAAGATATCGATCAAGGAATAACCTTTACTTATGATGAAATACCATCTGATATGATTGAAT
TATCTGAAAAGTGGCATCAAAATTTGATTGAGTCAGCTGTTGAATCTAATGAAGAATTAATGGAAAAATATTTAAGTGGC
TTTGTATTATCTGAAAAAGAAATAAAATCAGAATTAAGAAAACGATCTTTAAATAATGAAATTACACTTATCACCTGTGG
TTCTGCTTTTAAAAATAAAGGAGTGCAAGCATTATTGGATGCAATAATTGAATATTTACCTGCTCCTAACGATATTCAAG
ATATTAAGGGAATTACAAACGATAAAGCAAGTACTGTTGCTTTCAGATCTTCAAATGATAAAGCTCCATTTTCAGCTTTA
GCATTTAAAATTGCTAGTGATCCTTTTGTAGGTAATTTAACATTTTTTCGTGTATATTCAGGAATAGTAAAATCTGGAGA
TAGTGTTTTAAATTCTGTAAAATCTCAGCGTGAAAGATTTGGTAGAATTGTTCAAATGCATGCAAATAAAAGAGAAGAAA
TCAAAGAAGTTTATGCTGGAGATATAGCGGCAGCTATTGGTTTAAAAGATGTAACTACTGGTGATACACTATGTGATTTA
AATCAACCTATTATATTAGAACGAATGGAATTTCCAGAACCAGTTATATCTATTTCTGTAGAACCTAAAACAAAAGCTGA
TCAGGAAAAAATGGGTTTGGCATTAGCTAGATTAGCAAAAGAAGATCCTTCTTTTAGAGTTCGAACAGATCAAGAATCTA
ATCAAACAATCATTTCTGGAATGGGAGAATTACATTTAGAAATAATCGTTGATCGCATGAAACGAGAATTCAGTGTTGAT
GCTAATGTTGGCAAGCCACAAGTTGCATATCGTGAAACTATTCTGAATAAAGTAACTGATATAGAAGGAAAGCACATTAA
GCAATCTGGTGGAAGAGGTCAATATGGTCATGTTGTTATAGAATTATTTCCATTAGAATCAGGAGGTAAAGGATACTTAT
TTGTTAATGATATAAAAGGAGGAGTGATACCTAATGAATATATTTCAGCAATTGATAAAGGAATTCAAGAACAATTGAAG
TATGGACCCTTAGCTGGATATCCTGTTGTAGATATAGGAGTACGACTTTATTTTGGTTCATATCATGATGTTGATTCTTC
AGAATTAGCTTTTAAATTAGCAGCTTCTTTAGCATTTAAAAATGGATTTAAAAAAGCAAAACCAATTTTATTAGAACCTA
TTATGAAAGTAGAAGTAGAAACACCAGATGATTATATGGGAGATGTCATTGGTGACTTAAATCGTCGCCGAGGCATTATT
GAAGGCATGAAAGATTTAGAAATAGGTAAAATTATTAATGCATGTGTTCCTTTGTCAGAAATGTTTGGTTATGCTACTGA
TTTGCGTTCTCAAACTCAGGGTAGAGCTTCTTATTCCATGGAATTTTTAAAATATGTAGAAGCACCATCTGTTATTTCTG
ACTTAATCATTCAAAAAAGAGAGAGATAG

Upstream 100 bases:

>100_bases
GATTTCTATAAAATTTTTTAATTTATATAATATTGGGGCAATTGTTTTATTTTGCTCATACGGTGATAACTTTTAAAAAC
CTAAAAATGAGAAAACAATT

Downstream 100 bases:

>100_bases
TAAAATTTTTTTATAAAATAATTTTTAATAATAACTTTAAATAAAAAAGGGTTTAATAATGTCAAAAGAAAAATTTCAAC
GTGTAAAACCTCATATAAAT

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MSRTTPICQYRNIGISAHIDAGKTTTTERILFYTGINHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFK
PHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYNVPRIAFINKMDRMGANFLRSVKQIKT
RLGGNPVPLQLPIGSEENFKGVIDLIKMKAIKWKDIDQGITFTYDEIPSDMIELSEKWHQNLIESAVESNEELMEKYLSG
FVLSEKEIKSELRKRSLNNEITLITCGSAFKNKGVQALLDAIIEYLPAPNDIQDIKGITNDKASTVAFRSSNDKAPFSAL
AFKIASDPFVGNLTFFRVYSGIVKSGDSVLNSVKSQRERFGRIVQMHANKREEIKEVYAGDIAAAIGLKDVTTGDTLCDL
NQPIILERMEFPEPVISISVEPKTKADQEKMGLALARLAKEDPSFRVRTDQESNQTIISGMGELHLEIIVDRMKREFSVD
ANVGKPQVAYRETILNKVTDIEGKHIKQSGGRGQYGHVVIELFPLESGGKGYLFVNDIKGGVIPNEYISAIDKGIQEQLK
YGPLAGYPVVDIGVRLYFGSYHDVDSSELAFKLAASLAFKNGFKKAKPILLEPIMKVEVETPDDYMGDVIGDLNRRRGII
EGMKDLEIGKIINACVPLSEMFGYATDLRSQTQGRASYSMEFLKYVEAPSVISDLIIQKRER

Sequences:

>Translated_702_residues
MSRTTPICQYRNIGISAHIDAGKTTTTERILFYTGINHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFK
PHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYNVPRIAFINKMDRMGANFLRSVKQIKT
RLGGNPVPLQLPIGSEENFKGVIDLIKMKAIKWKDIDQGITFTYDEIPSDMIELSEKWHQNLIESAVESNEELMEKYLSG
FVLSEKEIKSELRKRSLNNEITLITCGSAFKNKGVQALLDAIIEYLPAPNDIQDIKGITNDKASTVAFRSSNDKAPFSAL
AFKIASDPFVGNLTFFRVYSGIVKSGDSVLNSVKSQRERFGRIVQMHANKREEIKEVYAGDIAAAIGLKDVTTGDTLCDL
NQPIILERMEFPEPVISISVEPKTKADQEKMGLALARLAKEDPSFRVRTDQESNQTIISGMGELHLEIIVDRMKREFSVD
ANVGKPQVAYRETILNKVTDIEGKHIKQSGGRGQYGHVVIELFPLESGGKGYLFVNDIKGGVIPNEYISAIDKGIQEQLK
YGPLAGYPVVDIGVRLYFGSYHDVDSSELAFKLAASLAFKNGFKKAKPILLEPIMKVEVETPDDYMGDVIGDLNRRRGII
EGMKDLEIGKIINACVPLSEMFGYATDLRSQTQGRASYSMEFLKYVEAPSVISDLIIQKRER
>Mature_701_residues
SRTTPICQYRNIGISAHIDAGKTTTTERILFYTGINHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFKP
HRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYNVPRIAFINKMDRMGANFLRSVKQIKTR
LGGNPVPLQLPIGSEENFKGVIDLIKMKAIKWKDIDQGITFTYDEIPSDMIELSEKWHQNLIESAVESNEELMEKYLSGF
VLSEKEIKSELRKRSLNNEITLITCGSAFKNKGVQALLDAIIEYLPAPNDIQDIKGITNDKASTVAFRSSNDKAPFSALA
FKIASDPFVGNLTFFRVYSGIVKSGDSVLNSVKSQRERFGRIVQMHANKREEIKEVYAGDIAAAIGLKDVTTGDTLCDLN
QPIILERMEFPEPVISISVEPKTKADQEKMGLALARLAKEDPSFRVRTDQESNQTIISGMGELHLEIIVDRMKREFSVDA
NVGKPQVAYRETILNKVTDIEGKHIKQSGGRGQYGHVVIELFPLESGGKGYLFVNDIKGGVIPNEYISAIDKGIQEQLKY
GPLAGYPVVDIGVRLYFGSYHDVDSSELAFKLAASLAFKNGFKKAKPILLEPIMKVEVETPDDYMGDVIGDLNRRRGIIE
GMKDLEIGKIINACVPLSEMFGYATDLRSQTQGRASYSMEFLKYVEAPSVISDLIIQKRER

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=706, Percent_Identity=44.9008498583569, Blast_Score=575, Evalue=1e-164,
Organism=Homo sapiens, GI19923640, Length=724, Percent_Identity=37.4309392265193, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI25306287, Length=698, Percent_Identity=36.3896848137536, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI25306283, Length=461, Percent_Identity=38.8286334056399, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI4503483, Length=470, Percent_Identity=27.2340425531915, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI94966754, Length=139, Percent_Identity=40.2877697841727, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI157426893, Length=159, Percent_Identity=36.4779874213836, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310132016, Length=120, Percent_Identity=39.1666666666667, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI310110807, Length=120, Percent_Identity=39.1666666666667, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI310123363, Length=120, Percent_Identity=39.1666666666667, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI94966752, Length=64, Percent_Identity=50, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789738, Length=702, Percent_Identity=80.4843304843305, Blast_Score=1188, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=489, Percent_Identity=26.9938650306748, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI48994988, Length=345, Percent_Identity=28.4057971014493, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788922, Length=153, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17533571, Length=696, Percent_Identity=42.0977011494253, Blast_Score=526, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17556745, Length=731, Percent_Identity=30.6429548563612, Blast_Score=308, Evalue=7e-84,
Organism=Caenorhabditis elegans, GI17506493, Length=505, Percent_Identity=25.5445544554455, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17557151, Length=167, Percent_Identity=38.9221556886228, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=146, Percent_Identity=33.5616438356164, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988811, Length=146, Percent_Identity=33.5616438356164, Blast_Score=80, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323098, Length=700, Percent_Identity=43.2857142857143, Blast_Score=561, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6322359, Length=783, Percent_Identity=32.3116219667944, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6324707, Length=473, Percent_Identity=24.3128964059197, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=473, Percent_Identity=24.3128964059197, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323320, Length=177, Percent_Identity=36.7231638418079, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=150, Percent_Identity=38, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582462, Length=710, Percent_Identity=43.943661971831, Blast_Score=583, Evalue=1e-166,
Organism=Drosophila melanogaster, GI221458488, Length=726, Percent_Identity=33.0578512396694, Blast_Score=360, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24585709, Length=477, Percent_Identity=25.5765199161426, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585711, Length=477, Percent_Identity=25.5765199161426, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585713, Length=477, Percent_Identity=25.5765199161426, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI78706572, Length=186, Percent_Identity=32.7956989247312, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574573, Length=142, Percent_Identity=37.3239436619718, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357743, Length=137, Percent_Identity=32.1167883211679, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 78322; Mature: 78191

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTTPICQYRNIGISAHIDAGKTTTTERILFYTGINHKIGEVHDGAATMDWMEQEQERG
CCCCCCCHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWSGMAKQFKPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQ
EEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEEEECCCCC
PQSETVWRQANKYNVPRIAFINKMDRMGANFLRSVKQIKTRLGGNPVPLQLPIGSEENFK
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHH
GVIDLIKMKAIKWKDIDQGITFTYDEIPSDMIELSEKWHQNLIESAVESNEELMEKYLSG
HHHHHHHHHHCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
FVLSEKEIKSELRKRSLNNEITLITCGSAFKNKGVQALLDAIIEYLPAPNDIQDIKGITN
EECCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCC
DKASTVAFRSSNDKAPFSALAFKIASDPFVGNLTFFRVYSGIVKSGDSVLNSVKSQRERF
CCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GRIVQMHANKREEIKEVYAGDIAAAIGLKDVTTGDTLCDLNQPIILERMEFPEPVISISV
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCEEHHHCCCCCEEEEEE
EPKTKADQEKMGLALARLAKEDPSFRVRTDQESNQTIISGMGELHLEIIVDRMKREFSVD
CCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ANVGKPQVAYRETILNKVTDIEGKHIKQSGGRGQYGHVVIELFPLESGGKGYLFVNDIKG
CCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCC
GVIPNEYISAIDKGIQEQLKYGPLAGYPVVDIGVRLYFGSYHDVDSSELAFKLAASLAFK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEECEEEEECCCCCCCHHHHHHHHHHHHHHH
NGFKKAKPILLEPIMKVEVETPDDYMGDVIGDLNRRRGIIEGMKDLEIGKIINACVPLSE
CCCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHH
MFGYATDLRSQTQGRASYSMEFLKYVEAPSVISDLIIQKRER
HHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRTTPICQYRNIGISAHIDAGKTTTTERILFYTGINHKIGEVHDGAATMDWMEQEQERG
CCCCCCHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWSGMAKQFKPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQ
EEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEEEECCCCC
PQSETVWRQANKYNVPRIAFINKMDRMGANFLRSVKQIKTRLGGNPVPLQLPIGSEENFK
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHH
GVIDLIKMKAIKWKDIDQGITFTYDEIPSDMIELSEKWHQNLIESAVESNEELMEKYLSG
HHHHHHHHHHCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
FVLSEKEIKSELRKRSLNNEITLITCGSAFKNKGVQALLDAIIEYLPAPNDIQDIKGITN
EECCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCC
DKASTVAFRSSNDKAPFSALAFKIASDPFVGNLTFFRVYSGIVKSGDSVLNSVKSQRERF
CCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GRIVQMHANKREEIKEVYAGDIAAAIGLKDVTTGDTLCDLNQPIILERMEFPEPVISISV
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCEEHHHCCCCCEEEEEE
EPKTKADQEKMGLALARLAKEDPSFRVRTDQESNQTIISGMGELHLEIIVDRMKREFSVD
CCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ANVGKPQVAYRETILNKVTDIEGKHIKQSGGRGQYGHVVIELFPLESGGKGYLFVNDIKG
CCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCC
GVIPNEYISAIDKGIQEQLKYGPLAGYPVVDIGVRLYFGSYHDVDSSELAFKLAASLAFK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEECEEEEECCCCCCCHHHHHHHHHHHHHHH
NGFKKAKPILLEPIMKVEVETPDDYMGDVIGDLNRRRGIIEGMKDLEIGKIINACVPLSE
CCCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHH
MFGYATDLRSQTQGRASYSMEFLKYVEAPSVISDLIIQKRER
HHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA