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The map label for this gene is htpG

Identifier: 21672733

GI number: 21672733

Start: 533996

End: 535873

Strand: Direct

Name: htpG

Synonym: BUsg468

Alternate gene names: 21672733

Gene position: 533996-535873 (Clockwise)

Preceding gene: 21672732

Following gene: 21672734

Centisome position: 83.25

GC content: 25.03

Gene sequence:

>1878_bases
ATGAATATACAAAAAAAAGAAGTATATAGTTTTCAATCTGAAGTAAAACAATTATTACATTTAATGATTCATTCTTTATA
TTCAAATAAAGAAATATTTTTAAGAGAATTAATATCTAATGCATCAGATGCAATAGATAAATTAAGATTTCAATCTATAT
CAAATCCAGAATTGTATGAAAATGATAGCGACTTTAAAATTCAAATATCTATTAATAAGTCTCAAGGTACTTTAATTATT
AGTGATAACGGTATTGGAATGACACGTCAAGATGTAGTTGAAAATTTAGGTACAATTGCAAAATCAGGAACTAAGTCATT
TATAAAATCTTTAGAAAAAAAAGAAAAAAATGTAAAAAATGAACTAATTGGAGAGTTTGGTGTCGGTTTTTATTCATCTT
TTATAGTATCAAAAAAAGTATCAGTAAGAACAAGGTTTGCAGGGAGTAAATCAAATCTAGGTGTATTATGGGAATCATCT
GGAGAAGGAGAATACAACATTACTGATATAAAGAAAAAAACTAGAGGTACCGAAATCACTTTATTTTTAAAAAAAGAAGA
AGAAGAGTTTTTAGAGTTATGGCGGATTGAAGGTATAGTCAGCAAGTATTCTGATCATATTACTGTACCAGTAAAAATAC
AAAAATATGATGAAAAAAATAAAATATATTTTTGGGAAAAAATCAATAAAGCCAAGGCATTATGGACACAAAACAAAGCT
ACTATTAGTGAAAAAGAATATCAAGAGTTTTATAAACACCTTACAAATGATCAAAATAACCCACTTTTTTGGAGTCATAA
TCATGTAGAAGGCATTAATGAATATATTAGTTTGTTATTTATTCCTGAAAAAGCTGCTTGGGACATTTGGAATAGAGATA
ATAAATCTGGTTTAAAATTGTATGTAAAACGTGTTTATATTATGGATAATTCTCAAGCTTTTCTTCCAAACTATTTAAGA
TTTATTAGAGGATTAATAGATTCAAATAATTTACCTTTAAATGTTTCTCGAGAAATATTACAAGATAACTCTATTACGCA
AAACTTAAAAAAAGCATTAATAAAAAGATCGTTAAAAATGCTTCAAACATTATCAAAAAAAGATAATGAAAAATATCAAA
TATTCTGGAATCAATTCGGATCAGTTTTAAAAGAAGGACCTGCTGAAGATAGTAACAATTTAAATTTAATTGCTAGTCTC
TTACGATTTACATCTATTCAAAATAATAGTTCTGAACAAAATATTTCACTAGAAAAATACATATCTAATATGCATGAAAA
ACAAGAAAAAATATATTATATTACTGCAGATAGTTACACATCAGCAAAAAATAGTCCACATTTAGAATTGTTTAATAAAA
AAAATATTGATGTTTTATTACTATCAGATAGAATTGATGAATGGATGATGAATTATCTTACTGAATTTGAAGGAAAAAAA
TTTCAATCCATCAGCAAAGAAGATCTATCATTGAATAAATTAACAAAAGAAAATGAAAATAAAAAAGAAACATCAACAGA
AATGATAGAATTTTTAAAAAAAGTAAAAAAAACTTTAGGTGATAAAGTAAAATCAGTACGGTTAACATATCGATTAACAG
AAACTCCATGTATCGTATTAAGTGATTCAAATGAAATGAGCACTCAAATGGCAAAACTATTTAGTGCAGCAGGACAAAGT
GTTCCAGAATTAAAATATATATTTGAAATCAATCCAGAACATAAATTAATACAAAAGATATGTAAAATAAAAGAAAACGA
AAAATTTGACGAGTGGATTAAATTATTATTAGATCAAGCACTATTTGCCGAAAAAGGAAATTTAGAAAATCCACATGAAT
TTATTGCTAGAACAAATAAATTAATTTTAGAACAATAA

Upstream 100 bases:

>100_bases
ATAAGAAAATAAAAAATTTTATTAATTGAACAATAAATTTTTAATAAATATTTTTTTTAAAAGGAATTATACATTTTATT
TTTTAAAAAAGAGATTTTAT

Downstream 100 bases:

>100_bases
AAATATGATTACTACTTTTTTATAGTAGTAATCTTACTCTTAAAATAATCTTTTAAACATGAAAAAATAATTATGCGTAT
TATTTTATTAGGTGCTCCAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MNIQKKEVYSFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFQSISNPELYENDSDFKIQISINKSQGTLII
SDNGIGMTRQDVVENLGTIAKSGTKSFIKSLEKKEKNVKNELIGEFGVGFYSSFIVSKKVSVRTRFAGSKSNLGVLWESS
GEGEYNITDIKKKTRGTEITLFLKKEEEEFLELWRIEGIVSKYSDHITVPVKIQKYDEKNKIYFWEKINKAKALWTQNKA
TISEKEYQEFYKHLTNDQNNPLFWSHNHVEGINEYISLLFIPEKAAWDIWNRDNKSGLKLYVKRVYIMDNSQAFLPNYLR
FIRGLIDSNNLPLNVSREILQDNSITQNLKKALIKRSLKMLQTLSKKDNEKYQIFWNQFGSVLKEGPAEDSNNLNLIASL
LRFTSIQNNSSEQNISLEKYISNMHEKQEKIYYITADSYTSAKNSPHLELFNKKNIDVLLLSDRIDEWMMNYLTEFEGKK
FQSISKEDLSLNKLTKENENKKETSTEMIEFLKKVKKTLGDKVKSVRLTYRLTETPCIVLSDSNEMSTQMAKLFSAAGQS
VPELKYIFEINPEHKLIQKICKIKENEKFDEWIKLLLDQALFAEKGNLENPHEFIARTNKLILEQ

Sequences:

>Translated_625_residues
MNIQKKEVYSFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFQSISNPELYENDSDFKIQISINKSQGTLII
SDNGIGMTRQDVVENLGTIAKSGTKSFIKSLEKKEKNVKNELIGEFGVGFYSSFIVSKKVSVRTRFAGSKSNLGVLWESS
GEGEYNITDIKKKTRGTEITLFLKKEEEEFLELWRIEGIVSKYSDHITVPVKIQKYDEKNKIYFWEKINKAKALWTQNKA
TISEKEYQEFYKHLTNDQNNPLFWSHNHVEGINEYISLLFIPEKAAWDIWNRDNKSGLKLYVKRVYIMDNSQAFLPNYLR
FIRGLIDSNNLPLNVSREILQDNSITQNLKKALIKRSLKMLQTLSKKDNEKYQIFWNQFGSVLKEGPAEDSNNLNLIASL
LRFTSIQNNSSEQNISLEKYISNMHEKQEKIYYITADSYTSAKNSPHLELFNKKNIDVLLLSDRIDEWMMNYLTEFEGKK
FQSISKEDLSLNKLTKENENKKETSTEMIEFLKKVKKTLGDKVKSVRLTYRLTETPCIVLSDSNEMSTQMAKLFSAAGQS
VPELKYIFEINPEHKLIQKICKIKENEKFDEWIKLLLDQALFAEKGNLENPHEFIARTNKLILEQ
>Mature_625_residues
MNIQKKEVYSFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFQSISNPELYENDSDFKIQISINKSQGTLII
SDNGIGMTRQDVVENLGTIAKSGTKSFIKSLEKKEKNVKNELIGEFGVGFYSSFIVSKKVSVRTRFAGSKSNLGVLWESS
GEGEYNITDIKKKTRGTEITLFLKKEEEEFLELWRIEGIVSKYSDHITVPVKIQKYDEKNKIYFWEKINKAKALWTQNKA
TISEKEYQEFYKHLTNDQNNPLFWSHNHVEGINEYISLLFIPEKAAWDIWNRDNKSGLKLYVKRVYIMDNSQAFLPNYLR
FIRGLIDSNNLPLNVSREILQDNSITQNLKKALIKRSLKMLQTLSKKDNEKYQIFWNQFGSVLKEGPAEDSNNLNLIASL
LRFTSIQNNSSEQNISLEKYISNMHEKQEKIYYITADSYTSAKNSPHLELFNKKNIDVLLLSDRIDEWMMNYLTEFEGKK
FQSISKEDLSLNKLTKENENKKETSTEMIEFLKKVKKTLGDKVKSVRLTYRLTETPCIVLSDSNEMSTQMAKLFSAAGQS
VPELKYIFEINPEHKLIQKICKIKENEKFDEWIKLLLDQALFAEKGNLENPHEFIARTNKLILEQ

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=642, Percent_Identity=34.5794392523364, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI154146191, Length=690, Percent_Identity=35.5072463768116, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI153792590, Length=687, Percent_Identity=35.5167394468704, Blast_Score=371, Evalue=1e-103,
Organism=Homo sapiens, GI20149594, Length=679, Percent_Identity=34.9042709867452, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI155722983, Length=632, Percent_Identity=32.753164556962, Blast_Score=345, Evalue=1e-94,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=63.3012820512821, Blast_Score=847, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=667, Percent_Identity=36.2818590704648, Blast_Score=406, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17542208, Length=669, Percent_Identity=33.6322869955157, Blast_Score=361, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI115535205, Length=637, Percent_Identity=31.5541601255887, Blast_Score=292, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI115535167, Length=426, Percent_Identity=34.9765258215962, Blast_Score=242, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6323840, Length=675, Percent_Identity=34.8148148148148, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=34.9633251833741, Blast_Score=252, Evalue=1e-67,
Organism=Drosophila melanogaster, GI21357739, Length=651, Percent_Identity=36.8663594470046, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24586016, Length=636, Percent_Identity=34.4339622641509, Blast_Score=358, Evalue=6e-99,
Organism=Drosophila melanogaster, GI17647529, Length=408, Percent_Identity=34.3137254901961, Blast_Score=259, Evalue=3e-69,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_BUCAP (Q8K981)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660800.1
- ProteinModelPortal:   Q8K981
- SMR:   Q8K981
- EnsemblBacteria:   EBBUCT00000000055
- GeneID:   1005408
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg468
- GeneTree:   EBGT00050000008181
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   BAPH198804:BUSG468-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72766; Mature: 72766

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQKKEVYSFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFQSISNPELYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NDSDFKIQISINKSQGTLIISDNGIGMTRQDVVENLGTIAKSGTKSFIKSLEKKEKNVKN
CCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ELIGEFGVGFYSSFIVSKKVSVRTRFAGSKSNLGVLWESSGEGEYNITDIKKKTRGTEIT
HHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCEEEEECCCCCCEEHHHHHHHCCCCEEE
LFLKKEEEEFLELWRIEGIVSKYSDHITVPVKIQKYDEKNKIYFWEKINKAKALWTQNKA
EEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEEHHCHHHHHHCCCCC
TISEKEYQEFYKHLTNDQNNPLFWSHNHVEGINEYISLLFIPEKAAWDIWNRDNKSGLKL
CCCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHEEECCCHHHHCCCCCCCCCCCEE
YVKRVYIMDNSQAFLPNYLRFIRGLIDSNNLPLNVSREILQDNSITQNLKKALIKRSLKM
EEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
LQTLSKKDNEKYQIFWNQFGSVLKEGPAEDSNNLNLIASLLRFTSIQNNSSEQNISLEKY
HHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
ISNMHEKQEKIYYITADSYTSAKNSPHLELFNKKNIDVLLLSDRIDEWMMNYLTEFEGKK
HHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHCCCH
FQSISKEDLSLNKLTKENENKKETSTEMIEFLKKVKKTLGDKVKSVRLTYRLTETPCIVL
HHCCCHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEE
SDSNEMSTQMAKLFSAAGQSVPELKYIFEINPEHKLIQKICKIKENEKFDEWIKLLLDQA
ECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LFAEKGNLENPHEFIARTNKLILEQ
HHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIQKKEVYSFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFQSISNPELYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NDSDFKIQISINKSQGTLIISDNGIGMTRQDVVENLGTIAKSGTKSFIKSLEKKEKNVKN
CCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ELIGEFGVGFYSSFIVSKKVSVRTRFAGSKSNLGVLWESSGEGEYNITDIKKKTRGTEIT
HHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCEEEEECCCCCCEEHHHHHHHCCCCEEE
LFLKKEEEEFLELWRIEGIVSKYSDHITVPVKIQKYDEKNKIYFWEKINKAKALWTQNKA
EEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEEHHCHHHHHHCCCCC
TISEKEYQEFYKHLTNDQNNPLFWSHNHVEGINEYISLLFIPEKAAWDIWNRDNKSGLKL
CCCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHEEECCCHHHHCCCCCCCCCCCEE
YVKRVYIMDNSQAFLPNYLRFIRGLIDSNNLPLNVSREILQDNSITQNLKKALIKRSLKM
EEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
LQTLSKKDNEKYQIFWNQFGSVLKEGPAEDSNNLNLIASLLRFTSIQNNSSEQNISLEKY
HHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
ISNMHEKQEKIYYITADSYTSAKNSPHLELFNKKNIDVLLLSDRIDEWMMNYLTEFEGKK
HHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHCCCH
FQSISKEDLSLNKLTKENENKKETSTEMIEFLKKVKKTLGDKVKSVRLTYRLTETPCIVL
HHCCCHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEE
SDSNEMSTQMAKLFSAAGQSVPELKYIFEINPEHKLIQKICKIKENEKFDEWIKLLLDQA
ECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LFAEKGNLENPHEFIARTNKLILEQ
HHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438