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The map label for this gene is murA

Identifier: 21672647

GI number: 21672647

Start: 426564

End: 427817

Strand: Direct

Name: murA

Synonym: BUsg373

Alternate gene names: 21672647

Gene position: 426564-427817 (Clockwise)

Preceding gene: 21672646

Following gene: 21672648

Centisome position: 66.5

GC content: 28.15

Gene sequence:

>1254_bases
ATGAATAAATTATATATAGAAGGCGATAAGAAATTAAATGGAAATGTTATAATTTCTGGTTCTAAAAACGCAGCTTTACC
TATTTTATTTATGACTATATTAACGGAAAAAAAAATTAAAATAAGTAATGTACCAAAATTAAGAGACATTAATATAGCAA
TCCAATTGCTAAAAAGTTTAGGAGCACAAATAAAATATAAAAAAAAAAATTTATATATTGATACAAGTTCAATAAAAATT
CACTCTCCACCCTATGATTTAACAAAGCAGATAAGAGCATCTATCTGGATGCTAGCACCTCTTCTAATTCGTTTTGGTAA
AGCTAAAATATTTTTACCAGGAGGTTGTAAAATAGGTGCTAGACCGATTGATCTTCATATTAAGGGCCTAATTGCATTAG
GCGCAAAAATTATTTTAGAAAAAAATTATATTTCTGCTTCTATTAAAAAACCCTTAACAGGAAAACGTATTTATATAGAA
AAAATTAGTGTAGGAGCAACTATTACTGTTATGAGTGCAGCTACACTAGCTCAAGGTACAACGATTATTGAAAATGCAGC
TCAAGAACCAGAAATTATTGACACGGCAAAATTTTTAAACACCTTAGGAGCAAATATTATTGGAGCAGGTAGTAATAGAA
TATTTATCAAAGGTGTTTTAACACTTATCGGAGGTAAACATAAAATTATACCAGATAGAATTGAAACAGGAACCTTTTTA
ATTGCAGCAGCAATATCTAAAGGATATATTATTTGCCATGATACTGAACCTAAATATTTAAAAAATGTATTAATGAAATT
ATCAGAATCAGGAGCGGAAATTAAAACAGGAAAAGATTGGATTCAATTAGATATGAGAGGTAAAAAACCGAAATCTATAA
ATATTTCAACTTCTCCATATCCAGGATTTCCAACAGATATGCAACCACAATTTGCTTTACTAAATAGTATTTCTCAAAGT
AAAGGTACTATTACTGAAAATATATTTGAAAACCGTTTTATTTATACTTCAGAACTGATTAAAATGGGAGCAAAAATAAA
AATAAAAAACAATTCTATTGTCTGTAAAGGTGTTCCTAATTTATATTCTCAAAATGTCTTTTCTAACGATTTGAGAGGAT
CAGCAACACTAGTTCTAGCCGGTTGTATTGCTAGAGGAACGACAACAGTTGATAATATTCATCATTTTGAAAGAGGATAT
GAAGCATTTTCTGAAAAATTAAATAAATTAGGAGCAAATATTAAATATATATAA

Upstream 100 bases:

>100_bases
ATAAAATTCATGCTATATCTATAAAATCTTACTCTTTAGAAGAGTGGGATAAAAATCAAAAATAAAGTATATTAAAAATA
GTATAGAGATTTCATAGTAA

Downstream 100 bases:

>100_bases
ATATTTTTTATATTTTAATAAAACAATTTATATTTATTTAAACTCAAAATTGAATTTTAATTAACAATTAAAATTTTTTT
AAAAAATAGGAGCATTATTA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNKLYIEGDKKLNGNVIISGSKNAALPILFMTILTEKKIKISNVPKLRDINIAIQLLKSLGAQIKYKKKNLYIDTSSIKI
HSPPYDLTKQIRASIWMLAPLLIRFGKAKIFLPGGCKIGARPIDLHIKGLIALGAKIILEKNYISASIKKPLTGKRIYIE
KISVGATITVMSAATLAQGTTIIENAAQEPEIIDTAKFLNTLGANIIGAGSNRIFIKGVLTLIGGKHKIIPDRIETGTFL
IAAAISKGYIICHDTEPKYLKNVLMKLSESGAEIKTGKDWIQLDMRGKKPKSINISTSPYPGFPTDMQPQFALLNSISQS
KGTITENIFENRFIYTSELIKMGAKIKIKNNSIVCKGVPNLYSQNVFSNDLRGSATLVLAGCIARGTTTVDNIHHFERGY
EAFSEKLNKLGANIKYI

Sequences:

>Translated_417_residues
MNKLYIEGDKKLNGNVIISGSKNAALPILFMTILTEKKIKISNVPKLRDINIAIQLLKSLGAQIKYKKKNLYIDTSSIKI
HSPPYDLTKQIRASIWMLAPLLIRFGKAKIFLPGGCKIGARPIDLHIKGLIALGAKIILEKNYISASIKKPLTGKRIYIE
KISVGATITVMSAATLAQGTTIIENAAQEPEIIDTAKFLNTLGANIIGAGSNRIFIKGVLTLIGGKHKIIPDRIETGTFL
IAAAISKGYIICHDTEPKYLKNVLMKLSESGAEIKTGKDWIQLDMRGKKPKSINISTSPYPGFPTDMQPQFALLNSISQS
KGTITENIFENRFIYTSELIKMGAKIKIKNNSIVCKGVPNLYSQNVFSNDLRGSATLVLAGCIARGTTTVDNIHHFERGY
EAFSEKLNKLGANIKYI
>Mature_417_residues
MNKLYIEGDKKLNGNVIISGSKNAALPILFMTILTEKKIKISNVPKLRDINIAIQLLKSLGAQIKYKKKNLYIDTSSIKI
HSPPYDLTKQIRASIWMLAPLLIRFGKAKIFLPGGCKIGARPIDLHIKGLIALGAKIILEKNYISASIKKPLTGKRIYIE
KISVGATITVMSAATLAQGTTIIENAAQEPEIIDTAKFLNTLGANIIGAGSNRIFIKGVLTLIGGKHKIIPDRIETGTFL
IAAAISKGYIICHDTEPKYLKNVLMKLSESGAEIKTGKDWIQLDMRGKKPKSINISTSPYPGFPTDMQPQFALLNSISQS
KGTITENIFENRFIYTSELIKMGAKIKIKNNSIVCKGVPNLYSQNVFSNDLRGSATLVLAGCIARGTTTVDNIHHFERGY
EAFSEKLNKLGANIKYI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=55.3956834532374, Blast_Score=507, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BUCAP (Q8K9G4)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660714.1
- ProteinModelPortal:   Q8K9G4
- SMR:   Q8K9G4
- EnsemblBacteria:   EBBUCT00000000477
- GeneID:   1005784
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg373
- GeneTree:   EBGT00050000008084
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   BAPH198804:BUSG373-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45758; Mature: 45758

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLYIEGDKKLNGNVIISGSKNAALPILFMTILTEKKIKISNVPKLRDINIAIQLLKSL
CCEEEEECCCEECCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHC
GAQIKYKKKNLYIDTSSIKIHSPPYDLTKQIRASIWMLAPLLIRFGKAKIFLPGGCKIGA
CCCEEEECCEEEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECC
RPIDLHIKGLIALGAKIILEKNYISASIKKPLTGKRIYIEKISVGATITVMSAATLAQGT
EEEEEEEEEHHHCCEEEEEECCHHHHHHCCCCCCCEEEEEEEECCEEEEEEEHHHHHCCC
TIIENAAQEPEIIDTAKFLNTLGANIIGAGSNRIFIKGVLTLIGGKHKIIPDRIETGTFL
HHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHHCCCCCCCCCCCCCCCEE
IAAAISKGYIICHDTEPKYLKNVLMKLSESGAEIKTGKDWIQLDMRGKKPKSINISTSPY
EEEECCCCEEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCEEEECCCCC
PGFPTDMQPQFALLNSISQSKGTITENIFENRFIYTSELIKMGAKIKIKNNSIVCKGVPN
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCEEEHHHHHHCCCEEEECCCCEEEECCCC
LYSQNVFSNDLRGSATLVLAGCIARGTTTVDNIHHFERGYEAFSEKLNKLGANIKYI
HHHCCCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MNKLYIEGDKKLNGNVIISGSKNAALPILFMTILTEKKIKISNVPKLRDINIAIQLLKSL
CCEEEEECCCEECCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHC
GAQIKYKKKNLYIDTSSIKIHSPPYDLTKQIRASIWMLAPLLIRFGKAKIFLPGGCKIGA
CCCEEEECCEEEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECC
RPIDLHIKGLIALGAKIILEKNYISASIKKPLTGKRIYIEKISVGATITVMSAATLAQGT
EEEEEEEEEHHHCCEEEEEECCHHHHHHCCCCCCCEEEEEEEECCEEEEEEEHHHHHCCC
TIIENAAQEPEIIDTAKFLNTLGANIIGAGSNRIFIKGVLTLIGGKHKIIPDRIETGTFL
HHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHHCCCCCCCCCCCCCCCEE
IAAAISKGYIICHDTEPKYLKNVLMKLSESGAEIKTGKDWIQLDMRGKKPKSINISTSPY
EEEECCCCEEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCEEEECCCCC
PGFPTDMQPQFALLNSISQSKGTITENIFENRFIYTSELIKMGAKIKIKNNSIVCKGVPN
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCEEEHHHHHHCCCEEEECCCCEEEECCCC
LYSQNVFSNDLRGSATLVLAGCIARGTTTVDNIHHFERGYEAFSEKLNKLGANIKYI
HHHCCCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438