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The map label for this gene is ybhE

Identifier: 21672561

GI number: 21672561

Start: 321600

End: 322601

Strand: Reverse

Name: ybhE

Synonym: BUsg282

Alternate gene names: 21672561

Gene position: 322601-321600 (Counterclockwise)

Preceding gene: 21672566

Following gene: 21672559

Centisome position: 50.29

GC content: 24.45

Gene sequence:

>1002_bases
ATGCAACAAATTATTTATATTGCTAACGCGGAAAGTGAAAATATAGAGGTCTGGATTTTATATAACAACGGAGATATGAA
ATTAATACAAACAGTTCAAACTGATGGTCAGGTACAACCTATTTCAATTATAAAAAATACAAAGTTATTATATGCTGGAA
TTCGTCCTAAGAATCGTGTTATTACCTATCAGATAGATAAAAACGGTTTATTGAAAAAAAAAAAAGAAAGTATTGTTCCT
GGTACTCCTAATTATATTTCTTTCGATAGCAGTGAAAAGTTTTTATTCTGTAGTTCTTATCATGCTGATTGCATAAGTGT
AAGTCCATTAGACAAAAATGGAATTCCTAAAGACCCAATACAAATTATTCATAATATTGAAGGTTGTCATGCTGCTAAAT
TCAATAGTAAATATAATGTTTTATTTATAACTTCATTAAAAAATGATTGTATTTATTTATATTACTTAACACATTTTGGT
ATATTGAAAAGCACAGAACAAAAATTAGTTTTTTCTCAAAAAAATTCAGGACCACGTCATGTTATATTTCATCCTAATCA
AAATTTTTCTTATACCGTTAATGAATTAAATGGTAGTGTTGACGTATGGAAAATATCTAAAGAAAATAAAGTATTAGAGG
TAAAAAACATACAAAATATAAAATTATTAAATGATTTGATTTCAAAAAAATATTGGTCTTCTGATATTCACTTAACTTCA
TGCGGCAATTTTTTATATGTATCCGATAGATATTTGAATAGTATTTCACTATTTCATGTTAATAAAAATGATAATACAAT
TATTTTTTTTAAACAATATCTTACAGAAGAACAACCTCGTGCATTTTGTATTGATAGAAATAATAATTATTTAATAGTTA
TTGGACAAAAATCTAATAAGTTAAGTGTATATAAAATTTGTCAAAAAACAGGTGAATTAAAAAAAATAAATCAATATCAA
ACAGGTAACGGTCCTTTATGGATAACTTCATTTTTAATTTAA

Upstream 100 bases:

>100_bases
ACAATATAAAATCAAAATAGATTAAAGTTATTCTTAAAAAATTTTATGAAGAATTATATAAAAAATATTTATTTTTTTAA
AAAAATATTGAGGAAAATGT

Downstream 100 bases:

>100_bases
ATTTTTCAAAGAGAAATATTATAAATTAAATATTTTCTACATTAAATAATGTATCATTATCTAAAGATTTTTCAATAACA
TTGATAAGTTTTTTTAAACA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6-P-gluconolactonase

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQQIIYIANAESENIEVWILYNNGDMKLIQTVQTDGQVQPISIIKNTKLLYAGIRPKNRVITYQIDKNGLLKKKKESIVP
GTPNYISFDSSEKFLFCSSYHADCISVSPLDKNGIPKDPIQIIHNIEGCHAAKFNSKYNVLFITSLKNDCIYLYYLTHFG
ILKSTEQKLVFSQKNSGPRHVIFHPNQNFSYTVNELNGSVDVWKISKENKVLEVKNIQNIKLLNDLISKKYWSSDIHLTS
CGNFLYVSDRYLNSISLFHVNKNDNTIIFFKQYLTEEQPRAFCIDRNNNYLIVIGQKSNKLSVYKICQKTGELKKINQYQ
TGNGPLWITSFLI

Sequences:

>Translated_333_residues
MQQIIYIANAESENIEVWILYNNGDMKLIQTVQTDGQVQPISIIKNTKLLYAGIRPKNRVITYQIDKNGLLKKKKESIVP
GTPNYISFDSSEKFLFCSSYHADCISVSPLDKNGIPKDPIQIIHNIEGCHAAKFNSKYNVLFITSLKNDCIYLYYLTHFG
ILKSTEQKLVFSQKNSGPRHVIFHPNQNFSYTVNELNGSVDVWKISKENKVLEVKNIQNIKLLNDLISKKYWSSDIHLTS
CGNFLYVSDRYLNSISLFHVNKNDNTIIFFKQYLTEEQPRAFCIDRNNNYLIVIGQKSNKLSVYKICQKTGELKKINQYQ
TGNGPLWITSFLI
>Mature_333_residues
MQQIIYIANAESENIEVWILYNNGDMKLIQTVQTDGQVQPISIIKNTKLLYAGIRPKNRVITYQIDKNGLLKKKKESIVP
GTPNYISFDSSEKFLFCSSYHADCISVSPLDKNGIPKDPIQIIHNIEGCHAAKFNSKYNVLFITSLKNDCIYLYYLTHFG
ILKSTEQKLVFSQKNSGPRHVIFHPNQNFSYTVNELNGSVDVWKISKENKVLEVKNIQNIKLLNDLISKKYWSSDIHLTS
CGNFLYVSDRYLNSISLFHVNKNDNTIIFFKQYLTEEQPRAFCIDRNNNYLIVIGQKSNKLSVYKICQKTGELKKINQYQ
TGNGPLWITSFLI

Specific function: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate

COG id: COG2706

COG function: function code G; 3-carboxymuconate cyclase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cycloisomerase 2 family

Homologues:

Organism=Escherichia coli, GI1786983, Length=329, Percent_Identity=37.0820668693009, Blast_Score=254, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 6PGL_BUCAP (Q8K9N9)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660628.1
- ProteinModelPortal:   Q8K9N9
- SMR:   Q8K9N9
- EnsemblBacteria:   EBBUCT00000000002
- GeneID:   1005486
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg282
- GeneTree:   EBGT00050000007987
- HOGENOM:   HBG741123
- OMA:   NIEGCHA
- ProtClustDB:   PRK11028
- BioCyc:   BAPH198804:BUSG282-MONOMER
- HAMAP:   MF_01605
- InterPro:   IPR022528
- InterPro:   IPR019405
- InterPro:   IPR015943
- Gene3D:   G3DSA:2.130.10.10

Pfam domain/function: PF10282 DUF2394

EC number: =3.1.1.31

Molecular weight: Translated: 38374; Mature: 38374

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQIIYIANAESENIEVWILYNNGDMKLIQTVQTDGQVQPISIIKNTKLLYAGIRPKNRV
CCEEEEEECCCCCCEEEEEEEECCCEEEEEEECCCCCEEEEEEEECCEEEEEECCCCCEE
ITYQIDKNGLLKKKKESIVPGTPNYISFDSSEKFLFCSSYHADCISVSPLDKNGIPKDPI
EEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCCHH
QIIHNIEGCHAAKFNSKYNVLFITSLKNDCIYLYYLTHFGILKSTEQKLVFSQKNSGPRH
HHHHCCCCCEEEECCCCEEEEEEEECCCCEEEEEEEHHCCHHCCCCCEEEEEECCCCCCE
VIFHPNQNFSYTVNELNGSVDVWKISKENKVLEVKNIQNIKLLNDLISKKYWSSDIHLTS
EEECCCCCCEEEEEECCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEE
CGNFLYVSDRYLNSISLFHVNKNDNTIIFFKQYLTEEQPRAFCIDRNNNYLIVIGQKSNK
CCCEEEEECCCCCEEEEEEEECCCCEEEEEEHHCCCCCCCEEEEECCCCEEEEEECCCCC
LSVYKICQKTGELKKINQYQTGNGPLWITSFLI
CHHHHHHHHCCCCEECCEEECCCCCEEEEEEEC
>Mature Secondary Structure
MQQIIYIANAESENIEVWILYNNGDMKLIQTVQTDGQVQPISIIKNTKLLYAGIRPKNRV
CCEEEEEECCCCCCEEEEEEEECCCEEEEEEECCCCCEEEEEEEECCEEEEEECCCCCEE
ITYQIDKNGLLKKKKESIVPGTPNYISFDSSEKFLFCSSYHADCISVSPLDKNGIPKDPI
EEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCCHH
QIIHNIEGCHAAKFNSKYNVLFITSLKNDCIYLYYLTHFGILKSTEQKLVFSQKNSGPRH
HHHHCCCCCEEEECCCCEEEEEEEECCCCEEEEEEEHHCCHHCCCCCEEEEEECCCCCCE
VIFHPNQNFSYTVNELNGSVDVWKISKENKVLEVKNIQNIKLLNDLISKKYWSSDIHLTS
EEECCCCCCEEEEEECCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEE
CGNFLYVSDRYLNSISLFHVNKNDNTIIFFKQYLTEEQPRAFCIDRNNNYLIVIGQKSNK
CCCEEEEECCCCCEEEEEEEECCCCEEEEEEHHCCCCCCCEEEEECCCCEEEEEECCCCC
LSVYKICQKTGELKKINQYQTGNGPLWITSFLI
CHHHHHHHHCCCCEECCEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438