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The map label for this gene is yadR

Identifier: 21672491

GI number: 21672491

Start: 232865

End: 233209

Strand: Reverse

Name: yadR

Synonym: BUsg205

Alternate gene names: 21672491

Gene position: 233209-232865 (Counterclockwise)

Preceding gene: 21672492

Following gene: 21672490

Centisome position: 36.36

GC content: 24.64

Gene sequence:

>345_bases
ATGGAAAAAAATCCTATAAAATACATTGAGTTCACTAATTCAGCTGCTAAAAAAATAAAAAGCATTATTAAAGAAAAAAA
AAATAAAAATGTAAAATTAAGAATATATATTATTGGTGGTGGATGCAGTGGATTTCAATATCAATTTATTTTCGATGAAA
AAATTAATGAAGATGATATTTTAGTTAAAAAATTAAATATTTGTCTTGTAATTGATCCCATCAGTTTACAGTATTTACAT
GGTGGTACAATAGATTATTTAGAAAATTTAGAAGGGTCAAAATTTATAGTATCTAATCCAAACGCTAAAAACACCTGCGG
ATGCGGTCTATCTTTCAGTATTTAA

Upstream 100 bases:

>100_bases
TTCATACTAAAAATATGTTTAAAATTGTTTTTTATGATAAAATTAAATAAAATATTTTATTTTCTAAAATTTCTTTAAAT
ATTTTGAGAATATATTAAAA

Downstream 100 bases:

>100_bases
AATATTGCATTAATTTTAAAAAATTAAAATTCTAAAAATTATTAATACTCTAAAAAAATTATATCTTATTGGAAAAAATG
AAAATTGGAATCATTGGTGC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MEKNPIKYIEFTNSAAKKIKSIIKEKKNKNVKLRIYIIGGGCSGFQYQFIFDEKINEDDILVKKLNICLVIDPISLQYLH
GGTIDYLENLEGSKFIVSNPNAKNTCGCGLSFSI

Sequences:

>Translated_114_residues
MEKNPIKYIEFTNSAAKKIKSIIKEKKNKNVKLRIYIIGGGCSGFQYQFIFDEKINEDDILVKKLNICLVIDPISLQYLH
GGTIDYLENLEGSKFIVSNPNAKNTCGCGLSFSI
>Mature_114_residues
MEKNPIKYIEFTNSAAKKIKSIIKEKKNKNVKLRIYIIGGGCSGFQYQFIFDEKINEDDILVKKLNICLVIDPISLQYLH
GGTIDYLENLEGSKFIVSNPNAKNTCGCGLSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=37.3831775700935, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=33.0188679245283, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=63.2075471698113, Blast_Score=156, Evalue=4e-40,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=32.0754716981132, Blast_Score=68, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=110, Percent_Identity=41.8181818181818, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=33.0188679245283, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=33.0188679245283, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=30.188679245283, Blast_Score=61, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24649697, Length=112, Percent_Identity=40.1785714285714, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_BUCAP (O51930)

Other databases:

- EMBL:   AF012886
- EMBL:   AE013218
- RefSeq:   NP_660558.1
- ProteinModelPortal:   O51930
- SMR:   O51930
- EnsemblBacteria:   EBBUCT00000000245
- GeneID:   1005402
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg205
- GeneTree:   EBGT00050000008089
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- BioCyc:   BAPH198804:BUSG205-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12838; Mature: 12838

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNPIKYIEFTNSAAKKIKSIIKEKKNKNVKLRIYIIGGGCSGFQYQFIFDEKINEDDI
CCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCE
LVKKLNICLVIDPISLQYLHGGTIDYLENLEGSKFIVSNPNAKNTCGCGLSFSI
EEEEEEEEEEECCCEEEEEECCCHHHHHCCCCCEEEEECCCCCCCCCCCEEECC
>Mature Secondary Structure
MEKNPIKYIEFTNSAAKKIKSIIKEKKNKNVKLRIYIIGGGCSGFQYQFIFDEKINEDDI
CCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCE
LVKKLNICLVIDPISLQYLHGGTIDYLENLEGSKFIVSNPNAKNTCGCGLSFSI
EEEEEEEEEEECCCEEEEEECCCHHHHHCCCCCEEEEECCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9425245; 12089438