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The map label for this gene is argE

Identifier: 21672337

GI number: 21672337

Start: 51160

End: 52305

Strand: Reverse

Name: argE

Synonym: BUsg044

Alternate gene names: 21672337

Gene position: 52305-51160 (Counterclockwise)

Preceding gene: 21672345

Following gene: 21672335

Centisome position: 8.15

GC content: 26.18

Gene sequence:

>1146_bases
ATGATAAGAAAAATACCTTCTTTTATTAAAATATATGAATCATTAATTAAAATACCTACTATTAGTAGTCTAAACAACAA
GCTTGATCAAAGTAATAAAGTTTTAATTGATCTATTATCTAATTATTTTTCTGAATTGAATTTTTTGATAAACATAAAAA
ATATTCCAAATACAAATAAATTCAATATGTTAGCCTCTTTTGGAGATGGAAAGGGAGGTATTTTATTTTCTGGACATACA
GATACTGTTGACTTTGATGAACACTTATGGACAAAAGATCCTTTTAAACTAACTGAGAAAAATAATAAATTATATGGATT
AGGTACAGTAGATATGAAAGGTTTTTTTGCTTTTATACTAGATGCTCTATGTTCGATAAACATAAAAAGTATAAAAAAAC
CAATTTATATTCTTGCAACTGCCAACGAAGAAACTGATATGTCAGGAGCGAGATATTTTATTCAATCTTCAAGTATAAAA
CCAGATTTTATTATTATTGGAGAACCGACATCTTTAAAATTAGTAAAAGCACATAAGGGGCACGTCTCTTATTCTATTGA
TGTTGTCGGTAATACTGGTCACTCAAGCAATCCTGCTAATGGTATTAACAGTATTGAAATTATGCATTTAGTTATAAAAA
AACTACTTAAATTGAAAATTTATTTAAGAGAAAAATATTTTCATAAAGACTTTTCTATTGGATATCCTACTATGAATTTT
TCTTCTATAAATGGAGGTAATGCAATTAATAGAATTTGTGCATTGTGCAACTTAAAATTTGAAATACGACCGACACCGGG
ATTGACTTTAACACAAATTGAAATTCTAATTCAAGAAATGTTACAAGCAATTTTTAAAAAATGGCCAAATCGCATTTTTT
TAAAAAATCTTTTTTTTTCTGTACCTCCATACGAGTTTCCTAAAGAAAAAAAAATCATTAAAAAAATAGAAAACTCATGT
CAATTAAAACCAACAACAGCTAATTATTGTACTGAAGCACCTTTTCTTGGCAAAATTGGACCAACTTTAATACTAGGACC
AGGTTCTATTCAACAAGCACATAATGCAGATGAATATTTAGATTGTTCTTTTATTAAACCTACTAAAAAAATAATAAGAA
AATTAATAAAAAACTTTTGTTATTAA

Upstream 100 bases:

>100_bases
CTATTAATTATTAAATTTTATTGATATTTTTTATTTTATATTTAAAATACATCATAATCATAAAAAAATTTAATAAATTA
CCTAAATAACATTACTTTAA

Downstream 100 bases:

>100_bases
ATAATATTTAAAAAAAATGATTTCTTTGATTATTATAAACCAAACATATGACATATAGAATATATTACATCTGATTTATT
TAAAGTATAAAAATGAAAAT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MIRKIPSFIKIYESLIKIPTISSLNNKLDQSNKVLIDLLSNYFSELNFLINIKNIPNTNKFNMLASFGDGKGGILFSGHT
DTVDFDEHLWTKDPFKLTEKNNKLYGLGTVDMKGFFAFILDALCSINIKSIKKPIYILATANEETDMSGARYFIQSSSIK
PDFIIIGEPTSLKLVKAHKGHVSYSIDVVGNTGHSSNPANGINSIEIMHLVIKKLLKLKIYLREKYFHKDFSIGYPTMNF
SSINGGNAINRICALCNLKFEIRPTPGLTLTQIEILIQEMLQAIFKKWPNRIFLKNLFFSVPPYEFPKEKKIIKKIENSC
QLKPTTANYCTEAPFLGKIGPTLILGPGSIQQAHNADEYLDCSFIKPTKKIIRKLIKNFCY

Sequences:

>Translated_381_residues
MIRKIPSFIKIYESLIKIPTISSLNNKLDQSNKVLIDLLSNYFSELNFLINIKNIPNTNKFNMLASFGDGKGGILFSGHT
DTVDFDEHLWTKDPFKLTEKNNKLYGLGTVDMKGFFAFILDALCSINIKSIKKPIYILATANEETDMSGARYFIQSSSIK
PDFIIIGEPTSLKLVKAHKGHVSYSIDVVGNTGHSSNPANGINSIEIMHLVIKKLLKLKIYLREKYFHKDFSIGYPTMNF
SSINGGNAINRICALCNLKFEIRPTPGLTLTQIEILIQEMLQAIFKKWPNRIFLKNLFFSVPPYEFPKEKKIIKKIENSC
QLKPTTANYCTEAPFLGKIGPTLILGPGSIQQAHNADEYLDCSFIKPTKKIIRKLIKNFCY
>Mature_381_residues
MIRKIPSFIKIYESLIKIPTISSLNNKLDQSNKVLIDLLSNYFSELNFLINIKNIPNTNKFNMLASFGDGKGGILFSGHT
DTVDFDEHLWTKDPFKLTEKNNKLYGLGTVDMKGFFAFILDALCSINIKSIKKPIYILATANEETDMSGARYFIQSSSIK
PDFIIIGEPTSLKLVKAHKGHVSYSIDVVGNTGHSSNPANGINSIEIMHLVIKKLLKLKIYLREKYFHKDFSIGYPTMNF
SSINGGNAINRICALCNLKFEIRPTPGLTLTQIEILIQEMLQAIFKKWPNRIFLKNLFFSVPPYEFPKEKKIIKKIENSC
QLKPTTANYCTEAPFLGKIGPTLILGPGSIQQAHNADEYLDCSFIKPTKKIIRKLIKNFCY

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily

Homologues:

Organism=Escherichia coli, GI1790395, Length=382, Percent_Identity=51.8324607329843, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789236, Length=324, Percent_Identity=24.3827160493827, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=355, Percent_Identity=23.0985915492958, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGE_BUCAP (P59085)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660404.1
- ProteinModelPortal:   P59085
- MEROPS:   M20.974
- EnsemblBacteria:   EBBUCT00000000494
- GeneID:   1005860
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg044
- GeneTree:   EBGT00050000008078
- HOGENOM:   HBG728841
- OMA:   RICGQCA
- ProtClustDB:   PRK05111
- BioCyc:   BAPH198804:BUSG044-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_01108
- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- TIGRFAMs:   TIGR01892

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.5.1.16

Molecular weight: Translated: 43122; Mature: 43122

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 81-81 ACT_SITE 143-143

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKIPSFIKIYESLIKIPTISSLNNKLDQSNKVLIDLLSNYFSELNFLINIKNIPNTNK
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEECCCCCCCC
FNMLASFGDGKGGILFSGHTDTVDFDEHLWTKDPFKLTEKNNKLYGLGTVDMKGFFAFIL
EEEEEECCCCCCCEEECCCCCCCCCHHHCCCCCCCEEECCCCEEEEEECCCHHHHHHHHH
DALCSINIKSIKKPIYILATANEETDMSGARYFIQSSSIKPDFIIIGEPTSLKLVKAHKG
HHHHCCCHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEEEECCC
HVSYSIDVVGNTGHSSNPANGINSIEIMHLVIKKLLKLKIYLREKYFHKDFSIGYPTMNF
CEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SSINGGNAINRICALCNLKFEIRPTPGLTLTQIEILIQEMLQAIFKKWPNRIFLKNLFFS
CCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHC
VPPYEFPKEKKIIKKIENSCQLKPTTANYCTEAPFLGKIGPTLILGPGSIQQAHNADEYL
CCCCCCCHHHHHHHHHHHCCEECCCCHHHHCCCCCCCCCCCEEEECCCCHHHHCCCCCCE
DCSFIKPTKKIIRKLIKNFCY
ECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRKIPSFIKIYESLIKIPTISSLNNKLDQSNKVLIDLLSNYFSELNFLINIKNIPNTNK
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEECCCCCCCC
FNMLASFGDGKGGILFSGHTDTVDFDEHLWTKDPFKLTEKNNKLYGLGTVDMKGFFAFIL
EEEEEECCCCCCCEEECCCCCCCCCHHHCCCCCCCEEECCCCEEEEEECCCHHHHHHHHH
DALCSINIKSIKKPIYILATANEETDMSGARYFIQSSSIKPDFIIIGEPTSLKLVKAHKG
HHHHCCCHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEEEECCC
HVSYSIDVVGNTGHSSNPANGINSIEIMHLVIKKLLKLKIYLREKYFHKDFSIGYPTMNF
CEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SSINGGNAINRICALCNLKFEIRPTPGLTLTQIEILIQEMLQAIFKKWPNRIFLKNLFFS
CCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHC
VPPYEFPKEKKIIKKIENSCQLKPTTANYCTEAPFLGKIGPTLILGPGSIQQAHNADEYL
CCCCCCCHHHHHHHHHHHCCEECCCCHHHHCCCCCCCCCCCEEEECCCCHHHHCCCCCCE
DCSFIKPTKKIIRKLIKNFCY
ECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438