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The map label for this gene is nagC [H]

Identifier: 213693305

GI number: 213693305

Start: 2776331

End: 2777539

Strand: Direct

Name: nagC [H]

Synonym: Blon_2459

Alternate gene names: 213693305

Gene position: 2776331-2777539 (Clockwise)

Preceding gene: 213693301

Following gene: 213693308

Centisome position: 98.01

GC content: 59.31

Gene sequence:

>1209_bases
ATGTCTGACGCCAATGCGATTCCGCAATGGTTTTCCGGATCCGAGCATACGCATCGCGTGGCGGCAGCCATCGCCCAATA
TGGGCCGATTGCGCGCACCACATTGGCACAGATGCTGGGATTGAGCCAGGGTGCGCTCTCCCGCATTACCAGCGATTTGA
TCTATGCCGGAGTCATCGAAGAACTGCCGGCTGTGGCCAGAACTACAGGCAAGCTGCCTGAACGGTTTACTCCCAAGGAG
AGCTCGGATCGTCGCGGCCGGCCGCAGACCGCATTGGTATTATGCTCGAACGCACGCACCTTCGTAGGCGTCAAAGTGCA
CGGCACATCCATTGTGTCGGCCGCCGTGAACGCGCATGGCGAGGTGGTTTCCAGCCGACATGAGATACCAATTGGTGCTG
ATCAGTCGGCAGAATATGTGACATCGTCGATAGCCACGCTGGTTCGTGAATGCTCTGATGATGTCGCCGCCACCGGCCTG
CCCGCTCCCACTGCCGTGGGCGTAGCGGTCGGAGGTCACGTGATCGATGATTCCATCGTCACGTTCGCCCCATTCCTGCA
CTGGGAGGGCACCACAGATTTAGGCGCAATGGTGTACGAGGCCACCGGATTGCCATGCGGCGTATTCAACGATATCGATT
CGCTGCTGGTGGATGCCTCCTGGTTCGGGCCGGGAGTGGGCGTGGATACGTTCGCCGTAGTGACCATCGGCGTGGGCGTG
GGCTATTCGCTGGCTGTGCATGGCGAACCGGTCAGTTACCCGGACAAGAGTTTTGGCCTAGTGGGGCATGTGCTCATCGA
CCCGGAGGGCCCGCGCTGCACCAGTGGGCATATCGGGTGTTCGCAATGCCTGACTGACGATTCGATTGCGGAACAGTATT
CGGCGATCATCGGCCGCGCAGCGACCTTCGATGATTTTGCGCACGATGCCAGAGCCCATGTGCCGCAAGCCTCTCAGCTA
GTGCACCGCACTTGCTTCCGATTGGGATCGCTGGTGGCCACCGTGGCGAACATCGCTATGCCGGGGCATGTAATGATCGC
CGGCGAATCGGCATTTTTGGCGAAGCTTGGTACCGATTCGCTGCGTGACGGCATCCGCTTCTATCGGCATAGCCAAACTC
AACCGGTGAAGTTCACGATTATGGATCACGACTGGCAGCTCTGGGCCAAAGCCGCTGCCAGCCGTGTAATCGTGAAGCAT
ATTGGGTAG

Upstream 100 bases:

>100_bases
GCGCCATTTCATTCCCAGCGCCAGCGAGCCCGCTTGCACAAGAAACAAAAAGCGCGGTATTTTGTGATTAACGCAATAAA
TAATGCAAAGGGGCTTAAGC

Downstream 100 bases:

>100_bases
GTCACTCCGCCACAGCTTTGAACAGTACTGCCTGCTGAGGGTGGAGGGACGGGGGACGGATGCCGTAACGCTGCAGGGCT
TCGCCGGTCAGGACTACGCC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSDANAIPQWFSGSEHTHRVAAAIAQYGPIARTTLAQMLGLSQGALSRITSDLIYAGVIEELPAVARTTGKLPERFTPKE
SSDRRGRPQTALVLCSNARTFVGVKVHGTSIVSAAVNAHGEVVSSRHEIPIGADQSAEYVTSSIATLVRECSDDVAATGL
PAPTAVGVAVGGHVIDDSIVTFAPFLHWEGTTDLGAMVYEATGLPCGVFNDIDSLLVDASWFGPGVGVDTFAVVTIGVGV
GYSLAVHGEPVSYPDKSFGLVGHVLIDPEGPRCTSGHIGCSQCLTDDSIAEQYSAIIGRAATFDDFAHDARAHVPQASQL
VHRTCFRLGSLVATVANIAMPGHVMIAGESAFLAKLGTDSLRDGIRFYRHSQTQPVKFTIMDHDWQLWAKAAASRVIVKH
IG

Sequences:

>Translated_402_residues
MSDANAIPQWFSGSEHTHRVAAAIAQYGPIARTTLAQMLGLSQGALSRITSDLIYAGVIEELPAVARTTGKLPERFTPKE
SSDRRGRPQTALVLCSNARTFVGVKVHGTSIVSAAVNAHGEVVSSRHEIPIGADQSAEYVTSSIATLVRECSDDVAATGL
PAPTAVGVAVGGHVIDDSIVTFAPFLHWEGTTDLGAMVYEATGLPCGVFNDIDSLLVDASWFGPGVGVDTFAVVTIGVGV
GYSLAVHGEPVSYPDKSFGLVGHVLIDPEGPRCTSGHIGCSQCLTDDSIAEQYSAIIGRAATFDDFAHDARAHVPQASQL
VHRTCFRLGSLVATVANIAMPGHVMIAGESAFLAKLGTDSLRDGIRFYRHSQTQPVKFTIMDHDWQLWAKAAASRVIVKH
IG
>Mature_401_residues
SDANAIPQWFSGSEHTHRVAAAIAQYGPIARTTLAQMLGLSQGALSRITSDLIYAGVIEELPAVARTTGKLPERFTPKES
SDRRGRPQTALVLCSNARTFVGVKVHGTSIVSAAVNAHGEVVSSRHEIPIGADQSAEYVTSSIATLVRECSDDVAATGLP
APTAVGVAVGGHVIDDSIVTFAPFLHWEGTTDLGAMVYEATGLPCGVFNDIDSLLVDASWFGPGVGVDTFAVVTIGVGVG
YSLAVHGEPVSYPDKSFGLVGHVLIDPEGPRCTSGHIGCSQCLTDDSIAEQYSAIIGRAATFDDFAHDARAHVPQASQLV
HRTCFRLGSLVATVANIAMPGHVMIAGESAFLAKLGTDSLRDGIRFYRHSQTQPVKFTIMDHDWQLWAKAAASRVIVKHI
G

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=398, Percent_Identity=22.6130653266332, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787878, Length=377, Percent_Identity=22.5464190981432, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42437; Mature: 42306

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDANAIPQWFSGSEHTHRVAAAIAQYGPIARTTLAQMLGLSQGALSRITSDLIYAGVIE
CCCCCCCCHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ELPAVARTTGKLPERFTPKESSDRRGRPQTALVLCSNARTFVGVKVHGTSIVSAAVNAHG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCHHHHHHHHCCH
EVVSSRHEIPIGADQSAEYVTSSIATLVRECSDDVAATGLPAPTAVGVAVGGHVIDDSIV
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEECCCHH
TFAPFLHWEGTTDLGAMVYEATGLPCGVFNDIDSLLVDASWFGPGVGVDTFAVVTIGVGV
HHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHEECHHCCCCCCCHHHHHEEEECCC
GYSLAVHGEPVSYPDKSFGLVGHVLIDPEGPRCTSGHIGCSQCLTDDSIAEQYSAIIGRA
CEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCC
ATFDDFAHDARAHVPQASQLVHRTCFRLGSLVATVANIAMPGHVMIAGESAFLAKLGTDS
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCHH
LRDGIRFYRHSQTQPVKFTIMDHDWQLWAKAAASRVIVKHIG
HHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDANAIPQWFSGSEHTHRVAAAIAQYGPIARTTLAQMLGLSQGALSRITSDLIYAGVIE
CCCCCCCHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ELPAVARTTGKLPERFTPKESSDRRGRPQTALVLCSNARTFVGVKVHGTSIVSAAVNAHG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCHHHHHHHHCCH
EVVSSRHEIPIGADQSAEYVTSSIATLVRECSDDVAATGLPAPTAVGVAVGGHVIDDSIV
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEECCCHH
TFAPFLHWEGTTDLGAMVYEATGLPCGVFNDIDSLLVDASWFGPGVGVDTFAVVTIGVGV
HHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHEECHHCCCCCCCHHHHHEEEECCC
GYSLAVHGEPVSYPDKSFGLVGHVLIDPEGPRCTSGHIGCSQCLTDDSIAEQYSAIIGRA
CEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCC
ATFDDFAHDARAHVPQASQLVHRTCFRLGSLVATVANIAMPGHVMIAGESAFLAKLGTDS
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCHH
LRDGIRFYRHSQTQPVKFTIMDHDWQLWAKAAASRVIVKHIG
HHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]