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The map label for this gene is xylR [H]

Identifier: 213693248

GI number: 213693248

Start: 2686688

End: 2687707

Strand: Direct

Name: xylR [H]

Synonym: Blon_2401

Alternate gene names: 213693248

Gene position: 2686688-2687707 (Clockwise)

Preceding gene: 213693242

Following gene: 213693249

Centisome position: 94.84

GC content: 55.29

Gene sequence:

>1020_bases
ATGAGTTTTGCAAGCATAATCCATCAGCATACGGTGATATCCGTGGACATCGGCGGCACCAAAATCGCCGCTGGTCTCAT
GTGCGTAGACCTCGACGAACAAGGAAGACCGCGGGACATGCCAGCGTTGATTCGACGGTACGTCATACCGACGAAAGCAC
GTCTCGGCGGCACCTCCGTATTGCAACGCGTCGTTCAAGCCATTCGCCAGTGTCTGGACGATGGTGAGATTCCTTTCCCA
CTATTGGGGATCGGTGTAGCGAGCGCAGGAGTCATTGACGGCAACGGTTCGGTGGTATCAGCCACTTCGTTGATTCCCGG
TTGGGCCGGTATTCAACTGCAAGCCGAATTATCGGCAACGTTCAACGTGCCTGCCATCGTCATCGGAGATGTTCAGGCAC
ACGCCCTTGGTGAAGCGCACTGGGGATGCGGACGACAATACCAATCACTACTGGTCGCCGCCATCGGCACCGGTATCGGA
GGCGCGATAATCATCGACGGGAAACTGGTACGCGGCGTCCACGGAGCCTGTGGCCATATCGGCCATCTGCCGCATCCCGA
CGCCATTGGTATATCCTGCTCATGTGGATGTGAGGGCCATGTGGAGTCAATCGCCTCAGGTACCGGCATTGCCGATAATT
ATCGACGTGCTCTGCAACAGAACGGACACAATACTCTCCCCACCGACATCAATGGACGCGCTATCGCCGAACTGGCCAGT
CAAGGTAGTACGGAAGCCGTAACCAGTATCACTCTGGCCGGCACGAGTCTCGGCGATGTTCTTGGCGGACTAATCAATGC
CCTTGATCCCGATGCCGTGATCCTTTCCGGCTCCGTAGTCCATTCTGGAGAGCTATGGATGAAATCTGTGAAACAAGGCA
TCCAAAGACAGACCTTGGGCATTCTTTCCCGAACACCGGTTTTGACAGGAACACTCGGCGGCAGAGCCCCTCTCATCGGA
GCAACATCAGCTCTGTGCGCCGACCTCAGATCAAATAAGGAGCAGAAATATGAATACTAA

Upstream 100 bases:

>100_bases
TCGTTGTCGTACTCGGAGGAAGCCTGATAACAATAAAAGCGGAGGCGAACTGACGCAGTGCAGTCGCCCATACCGCTTAA
TCACACCAACGGAGATGCCT

Downstream 100 bases:

>100_bases
CGATACTTATTCGAAACGTCTTATTGATTCGCTCCACGGCACACTGATAGTCAGCTGTCAAGCATATCCCGGCGAGCCAA
TGCGGCATCCCGAAACCATG

Product: ROK family protein

Products: ADP; D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSFASIIHQHTVISVDIGGTKIAAGLMCVDLDEQGRPRDMPALIRRYVIPTKARLGGTSVLQRVVQAIRQCLDDGEIPFP
LLGIGVASAGVIDGNGSVVSATSLIPGWAGIQLQAELSATFNVPAIVIGDVQAHALGEAHWGCGRQYQSLLVAAIGTGIG
GAIIIDGKLVRGVHGACGHIGHLPHPDAIGISCSCGCEGHVESIASGTGIADNYRRALQQNGHNTLPTDINGRAIAELAS
QGSTEAVTSITLAGTSLGDVLGGLINALDPDAVILSGSVVHSGELWMKSVKQGIQRQTLGILSRTPVLTGTLGGRAPLIG
ATSALCADLRSNKEQKYEY

Sequences:

>Translated_339_residues
MSFASIIHQHTVISVDIGGTKIAAGLMCVDLDEQGRPRDMPALIRRYVIPTKARLGGTSVLQRVVQAIRQCLDDGEIPFP
LLGIGVASAGVIDGNGSVVSATSLIPGWAGIQLQAELSATFNVPAIVIGDVQAHALGEAHWGCGRQYQSLLVAAIGTGIG
GAIIIDGKLVRGVHGACGHIGHLPHPDAIGISCSCGCEGHVESIASGTGIADNYRRALQQNGHNTLPTDINGRAIAELAS
QGSTEAVTSITLAGTSLGDVLGGLINALDPDAVILSGSVVHSGELWMKSVKQGIQRQTLGILSRTPVLTGTLGGRAPLIG
ATSALCADLRSNKEQKYEY
>Mature_338_residues
SFASIIHQHTVISVDIGGTKIAAGLMCVDLDEQGRPRDMPALIRRYVIPTKARLGGTSVLQRVVQAIRQCLDDGEIPFPL
LGIGVASAGVIDGNGSVVSATSLIPGWAGIQLQAELSATFNVPAIVIGDVQAHALGEAHWGCGRQYQSLLVAAIGTGIGG
AIIIDGKLVRGVHGACGHIGHLPHPDAIGISCSCGCEGHVESIASGTGIADNYRRALQQNGHNTLPTDINGRAIAELASQ
GSTEAVTSITLAGTSLGDVLGGLINALDPDAVILSGSVVHSGELWMKSVKQGIQRQTLGILSRTPVLTGTLGGRAPLIGA
TSALCADLRSNKEQKYEY

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=303, Percent_Identity=26.0726072607261, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI298566325, Length=305, Percent_Identity=24.9180327868852, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4885285, Length=306, Percent_Identity=26.797385620915, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI190014632, Length=306, Percent_Identity=26.797385620915, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786891, Length=277, Percent_Identity=23.4657039711191, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081733, Length=220, Percent_Identity=28.6363636363636, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787363, Length=275, Percent_Identity=26.5454545454545, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787878, Length=249, Percent_Identity=23.2931726907631, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: 2.7.1.2

Molecular weight: Translated: 34918; Mature: 34787

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFASIIHQHTVISVDIGGTKIAAGLMCVDLDEQGRPRDMPALIRRYVIPTKARLGGTSV
CCHHHHHHHCEEEEEECCCHHHHHCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
LQRVVQAIRQCLDDGEIPFPLLGIGVASAGVIDGNGSVVSATSLIPGWAGIQLQAELSAT
HHHHHHHHHHHHCCCCCCCCCEEHHHHHCCEECCCCCEEEEHHCCCCCCCEEEEEEECEE
FNVPAIVIGDVQAHALGEAHWGCGRQYQSLLVAAIGTGIGGAIIIDGKLVRGVHGACGHI
CCCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHCCCCHHHHCC
GHLPHPDAIGISCSCGCEGHVESIASGTGIADNYRRALQQNGHNTLPTDINGRAIAELAS
CCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
QGSTEAVTSITLAGTSLGDVLGGLINALDPDAVILSGSVVHSGELWMKSVKQGIQRQTLG
CCCCHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEECCEEECHHHHHHHHHHHHHHHHHH
ILSRTPVLTGTLGGRAPLIGATSALCADLRSNKEQKYEY
HHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
SFASIIHQHTVISVDIGGTKIAAGLMCVDLDEQGRPRDMPALIRRYVIPTKARLGGTSV
CHHHHHHHCEEEEEECCCHHHHHCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
LQRVVQAIRQCLDDGEIPFPLLGIGVASAGVIDGNGSVVSATSLIPGWAGIQLQAELSAT
HHHHHHHHHHHHCCCCCCCCCEEHHHHHCCEECCCCCEEEEHHCCCCCCCEEEEEEECEE
FNVPAIVIGDVQAHALGEAHWGCGRQYQSLLVAAIGTGIGGAIIIDGKLVRGVHGACGHI
CCCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHCCCCHHHHCC
GHLPHPDAIGISCSCGCEGHVESIASGTGIADNYRRALQQNGHNTLPTDINGRAIAELAS
CCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
QGSTEAVTSITLAGTSLGDVLGGLINALDPDAVILSGSVVHSGELWMKSVKQGIQRQTLG
CCCCHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEECCEEECHHHHHHHHHHHHHHHHHH
ILSRTPVLTGTLGGRAPLIGATSALCADLRSNKEQKYEY
HHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-glucose

Specific reaction: ATP + D-glucose = ADP + D-glucose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]