Click here to switch to the map view.

The map label for this gene is yicO [C]

Identifier: 213693119

GI number: 213693119

Start: 2504671

End: 2506065

Strand: Direct

Name: yicO [C]

Synonym: Blon_2269

Alternate gene names: 213693119

Gene position: 2504671-2506065 (Clockwise)

Preceding gene: 213693112

Following gene: 213693128

Centisome position: 88.42

GC content: 62.87

Gene sequence:

>1395_bases
ATGGAGAAATTCTTCCATTTGAAGGAAAACGGCACGACCGTCTCGACTGAGATTCTGGCCGGCCTGACCACGTTCTTCGC
GATGGCCTACGTCATCGTCGTCAACCCGCAGATCCTGTCGCAGACGGGCATGCCGTGGGGCGGCGTGTTCCTGGCCACCA
TCATCGCCGCCATCATCGGCACCCTGGTCATGGGCCTGTTCGCCAACGTGCCGTACGCCCAGGCCGCCGGCATGGGCCTC
AACGCGTTCTTCACCTACACCGTATGCTTCGGCCTCGGCTTCACCTGGCAGCAGACCATGTGCATGGTGTTCCTGTGCGG
CCTGATCAACATCCTCATCACCGTCACCAGAATCCGCAAGATGATCATCCTGGCCATCCCCGAGCCTCTGCAGCGCGCCA
TCGGCGGCGGCATCGGCCTGTTCGTGGCCTATGTGGGCATGCTGAACGTCGGACTGATCAAGTTCACCCCCGGCGACCCG
AAAGCCGCGGCCAAGGGAGGCGCCGTGGCGGCGACCCCGGGTCTGGCCGACTTCAACGACAAGGTGCTGTGGGTCTTCCT
GATCGGCCTCGTACTGGCCATTGTGTTCACCGTGATGAAGGTTAAGGGCGGCATGCTGCTGGCCATCGCCATCACCACCG
TGATCGGCATCCCGTTCGGCGTTACCACCTGGTCCAACTCGCAGTCCATCAGCGAAACCTTCTCCCAGCTGCCGCAGACC
TTCGGCGCGATCTTCTCCGCTGAGGGCTTCCCGGCGCTGTTCTCCGACGTCTCCAAGCTGCCTCTGGTCATCGTGACCAT
CTTCGCCTTCTCCATGTCCGATACGTTCGACACCCTGGGCACTTTCATCGGCACCGGCCGCCGCACCGGCATCTTCTCCG
CCGAGGATGAGAAGGCTCTGGAGAACGGTCACGGCTTCTCCTCCAAGATGGACAAGGCCCTGTTCGCCGACTCCATCGCC
ACCTCCATTGGCGCTATCTGCGGCACCTCGAACACCACCACCTACGTCGAGTCTTCCGCCGGCATCGCCGCAGGCGGCCG
CACCGGCCTGACCTCCGTGGTTGTGGCGATCTGCTTCGCCCTGTCCGCGTTCCTGGCCCCGGTCGTCTCTGCCGTGCCGT
CCGCCGCAACCGCCGGCGTGCTGGTGATCGTCGGCTGCATGATGGCCGCCTCCCTGAAGGAAGTCAGGTGGGACGACATC
GCCGAAGCCATCCCGGCGTTCTTCGCAGCCGTGTTCATGGCCTTCTCCTACTCCATCTCCTACGGCATCGCCGGCGGCTT
CATCATGTACTGCATCGTGAAGACCTGCAAGGGCAAGGCCAAGGAGGTTCACCCGATCATCTGGATTGTGGCCGCGCTGT
TCATTCTGGACTTCGTGTGCATGGCGATTCTGTGA

Upstream 100 bases:

>100_bases
GGCAGGCCGATCAGGGCGAGTCGCAATTCTCGCCGGGGCCAGCCGCAGCATTATGCGCGCGGTGCGCAGCCCCGCATAAA
CCCAAGGAAGTAGAGAGTAG

Downstream 100 bases:

>100_bases
CGCTGATTGACGACAGATTAGCCTTTAAGGATTAATCCGCCGCCATACGGCATAAAGGCCGGGCTCTCACAAGGGCCCGG
CCTTTGTTGTTGCCACAGTG

Product: Xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MEKFFHLKENGTTVSTEILAGLTTFFAMAYVIVVNPQILSQTGMPWGGVFLATIIAAIIGTLVMGLFANVPYAQAAGMGL
NAFFTYTVCFGLGFTWQQTMCMVFLCGLINILITVTRIRKMIILAIPEPLQRAIGGGIGLFVAYVGMLNVGLIKFTPGDP
KAAAKGGAVAATPGLADFNDKVLWVFLIGLVLAIVFTVMKVKGGMLLAIAITTVIGIPFGVTTWSNSQSISETFSQLPQT
FGAIFSAEGFPALFSDVSKLPLVIVTIFAFSMSDTFDTLGTFIGTGRRTGIFSAEDEKALENGHGFSSKMDKALFADSIA
TSIGAICGTSNTTTYVESSAGIAAGGRTGLTSVVVAICFALSAFLAPVVSAVPSAATAGVLVIVGCMMAASLKEVRWDDI
AEAIPAFFAAVFMAFSYSISYGIAGGFIMYCIVKTCKGKAKEVHPIIWIVAALFILDFVCMAIL

Sequences:

>Translated_464_residues
MEKFFHLKENGTTVSTEILAGLTTFFAMAYVIVVNPQILSQTGMPWGGVFLATIIAAIIGTLVMGLFANVPYAQAAGMGL
NAFFTYTVCFGLGFTWQQTMCMVFLCGLINILITVTRIRKMIILAIPEPLQRAIGGGIGLFVAYVGMLNVGLIKFTPGDP
KAAAKGGAVAATPGLADFNDKVLWVFLIGLVLAIVFTVMKVKGGMLLAIAITTVIGIPFGVTTWSNSQSISETFSQLPQT
FGAIFSAEGFPALFSDVSKLPLVIVTIFAFSMSDTFDTLGTFIGTGRRTGIFSAEDEKALENGHGFSSKMDKALFADSIA
TSIGAICGTSNTTTYVESSAGIAAGGRTGLTSVVVAICFALSAFLAPVVSAVPSAATAGVLVIVGCMMAASLKEVRWDDI
AEAIPAFFAAVFMAFSYSISYGIAGGFIMYCIVKTCKGKAKEVHPIIWIVAALFILDFVCMAIL
>Mature_464_residues
MEKFFHLKENGTTVSTEILAGLTTFFAMAYVIVVNPQILSQTGMPWGGVFLATIIAAIIGTLVMGLFANVPYAQAAGMGL
NAFFTYTVCFGLGFTWQQTMCMVFLCGLINILITVTRIRKMIILAIPEPLQRAIGGGIGLFVAYVGMLNVGLIKFTPGDP
KAAAKGGAVAATPGLADFNDKVLWVFLIGLVLAIVFTVMKVKGGMLLAIAITTVIGIPFGVTTWSNSQSISETFSQLPQT
FGAIFSAEGFPALFSDVSKLPLVIVTIFAFSMSDTFDTLGTFIGTGRRTGIFSAEDEKALENGHGFSSKMDKALFADSIA
TSIGAICGTSNTTTYVESSAGIAAGGRTGLTSVVVAICFALSAFLAPVVSAVPSAATAGVLVIVGCMMAASLKEVRWDDI
AEAIPAFFAAVFMAFSYSISYGIAGGFIMYCIVKTCKGKAKEVHPIIWIVAALFILDFVCMAIL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=459, Percent_Identity=38.3442265795207, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1790150, Length=459, Percent_Identity=37.2549019607843, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1790499, Length=448, Percent_Identity=30.5803571428571, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI48994909, Length=449, Percent_Identity=30.0668151447661, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48810; Mature: 48810

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKFFHLKENGTTVSTEILAGLTTFFAMAYVIVVNPQILSQTGMPWGGVFLATIIAAIIG
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHH
TLVMGLFANVPYAQAAGMGLNAFFTYTVCFGLGFTWQQTMCMVFLCGLINILITVTRIRK
HHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MIILAIPEPLQRAIGGGIGLFVAYVGMLNVGLIKFTPGDPKAAAKGGAVAATPGLADFND
HHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCEEEECCCCCCHHCCCCCEEECCCCCCCCC
KVLWVFLIGLVLAIVFTVMKVKGGMLLAIAITTVIGIPFGVTTWSNSQSISETFSQLPQT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FGAIFSAEGFPALFSDVSKLPLVIVTIFAFSMSDTFDTLGTFIGTGRRTGIFSAEDEKAL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ENGHGFSSKMDKALFADSIATSIGAICGTSNTTTYVESSAGIAAGGRTGLTSVVVAICFA
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH
LSAFLAPVVSAVPSAATAGVLVIVGCMMAASLKEVRWDDIAEAIPAFFAAVFMAFSYSIS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIAGGFIMYCIVKTCKGKAKEVHPIIWIVAALFILDFVCMAIL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEKFFHLKENGTTVSTEILAGLTTFFAMAYVIVVNPQILSQTGMPWGGVFLATIIAAIIG
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHH
TLVMGLFANVPYAQAAGMGLNAFFTYTVCFGLGFTWQQTMCMVFLCGLINILITVTRIRK
HHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MIILAIPEPLQRAIGGGIGLFVAYVGMLNVGLIKFTPGDPKAAAKGGAVAATPGLADFND
HHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCEEEECCCCCCHHCCCCCEEECCCCCCCCC
KVLWVFLIGLVLAIVFTVMKVKGGMLLAIAITTVIGIPFGVTTWSNSQSISETFSQLPQT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FGAIFSAEGFPALFSDVSKLPLVIVTIFAFSMSDTFDTLGTFIGTGRRTGIFSAEDEKAL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ENGHGFSSKMDKALFADSIATSIGAICGTSNTTTYVESSAGIAAGGRTGLTSVVVAICFA
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH
LSAFLAPVVSAVPSAATAGVLVIVGCMMAASLKEVRWDDIAEAIPAFFAAVFMAFSYSIS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIAGGFIMYCIVKTCKGKAKEVHPIIWIVAALFILDFVCMAIL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]