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The map label for this gene is dinB [H]

Identifier: 213693101

GI number: 213693101

Start: 2483876

End: 2485222

Strand: Direct

Name: dinB [H]

Synonym: Blon_2250

Alternate gene names: 213693101

Gene position: 2483876-2485222 (Clockwise)

Preceding gene: 213693094

Following gene: 213693110

Centisome position: 87.68

GC content: 62.88

Gene sequence:

>1347_bases
ATGACAATGAGCGCCGCGCCATGCGCGCCACATAGTGAGCATGACCTCGTTCGGCATTCCTACAATGGTGGTATGAGCAC
CGCACCGAGACTTGAGGCCGCCAAACGCGATTGGGGTCACGACGAGACCGGATGCACCGTGCTGCATATCGACATGGATG
CCTTCTATGCCTCATTGGAGGTGGCGCGCAACCCCGGGCTCAAAGGCAAGCCGGTGATCATCGGCACCGGGCCGCGCGCG
GTGGTGTCCGCCGCGAGCTACGAAGCCCGGAGATACGGCATCAATTCGGCGATGCCGGCCGCGCGCGCCCATCAGTTGTG
CCCGAACGGCGTCTTTCTGCCGGTGGATATGGCGTATTACCGCATGATGTCGCACCGAATCATGCACGAGGTGTTTTTGA
CCGTCACCGACCGGTTCGAGCAGGTTTCGGTGGACGAGGGCTATATGGATGTGTCCACCGCACTGCTGGAGTGGGGGCGA
CCGAGCGCGATCGGCGCGTGGATTCGCGCTCAGGTGGCCGAGCGCTTCCACGTGACGTGTTCAGTGGGTATCGCCTGTAA
CAAGCTGGTGGCCAAAATGGCCTCGACCAATGCCAAGCCGGACGGCATGCTGCTGATTCCGGCGGCCCGCTCGGCTGAGT
TCGTGCAGATGATGCCATTGCGTGGCATTCCGGGCATCGGGCCGTCTTTGGAGAAGCGGCTTAATGCTTGGGGCGTGCAT
TCGGTGGCTGAATTGGCTCAGCTGGATGAGACTGCATTGACTCGTGCCACTGGCTCCCCGGCTGCGGCACGTGGATTATG
GGCGGCCTCGCACGGGTTGGATTCCCGCAAAATTACCACGGTGCGCGAGGAGAAATCCATTGGGTCCGAGGAAACCTTGG
CCGAGGATACACGCGATATGCGCGTGGTGTGTGGGCTACTGCGTTCGGCCTGCGACGAAGTAGCCAGCACGCTGCGGCGC
AAGGGGCTGGTGGCGCGCACGCTGACGGTGAAGTTGCGGTTCGCCGACCTGAGCTATCAGACCCGGTCTTTTACGATGGA
GCGGCCGACCGATACGGCCGGCGTGCTGTACCCGGAATGCGTGCGGCAGCTGAAAGTCATGCTGGGGCTACCGGCCTCGG
CGGAGTCTGCCACTCCCCTGCCCAAAACTATTCGCTTGGCCGGTATGAGCACGTCTTCGCTCAGCGAGGCGGCGGCTACG
GCCGTGCAGCCTTCACTGGATGACATGCTTGAAGAGGCCGCCAATGCCCGCGGCCAGACCTCACAGGCACGTTTGCATGA
TGCCGAGGCCGCACTGGACGCTGTGCGCCGCAAATTTGGCAGCAAGGCCGCCCAGTTTGGGGCGTGA

Upstream 100 bases:

>100_bases
GGACAGTGACGCAATGTGGACGATTCCGTGGAATCGCACCCACCATGCGAAACAGCCGCACAGTGCGCAAACCCTTGGAA
TTCCGGTGATATTCGGCATT

Downstream 100 bases:

>100_bases
ACGGCTCAACGCCACTTGCGATCTCATTACGCCGTGAGACGTTCGCAGGCGGAGCGGATGGCCTCGTCGGTGGCGGTGGC
GGAGAAACGCAGGTAGGCGG

Product: transcriptional regulator, Fis family

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTMSAAPCAPHSEHDLVRHSYNGGMSTAPRLEAAKRDWGHDETGCTVLHIDMDAFYASLEVARNPGLKGKPVIIGTGPRA
VVSAASYEARRYGINSAMPAARAHQLCPNGVFLPVDMAYYRMMSHRIMHEVFLTVTDRFEQVSVDEGYMDVSTALLEWGR
PSAIGAWIRAQVAERFHVTCSVGIACNKLVAKMASTNAKPDGMLLIPAARSAEFVQMMPLRGIPGIGPSLEKRLNAWGVH
SVAELAQLDETALTRATGSPAAARGLWAASHGLDSRKITTVREEKSIGSEETLAEDTRDMRVVCGLLRSACDEVASTLRR
KGLVARTLTVKLRFADLSYQTRSFTMERPTDTAGVLYPECVRQLKVMLGLPASAESATPLPKTIRLAGMSTSSLSEAAAT
AVQPSLDDMLEEAANARGQTSQARLHDAEAALDAVRRKFGSKAAQFGA

Sequences:

>Translated_448_residues
MTMSAAPCAPHSEHDLVRHSYNGGMSTAPRLEAAKRDWGHDETGCTVLHIDMDAFYASLEVARNPGLKGKPVIIGTGPRA
VVSAASYEARRYGINSAMPAARAHQLCPNGVFLPVDMAYYRMMSHRIMHEVFLTVTDRFEQVSVDEGYMDVSTALLEWGR
PSAIGAWIRAQVAERFHVTCSVGIACNKLVAKMASTNAKPDGMLLIPAARSAEFVQMMPLRGIPGIGPSLEKRLNAWGVH
SVAELAQLDETALTRATGSPAAARGLWAASHGLDSRKITTVREEKSIGSEETLAEDTRDMRVVCGLLRSACDEVASTLRR
KGLVARTLTVKLRFADLSYQTRSFTMERPTDTAGVLYPECVRQLKVMLGLPASAESATPLPKTIRLAGMSTSSLSEAAAT
AVQPSLDDMLEEAANARGQTSQARLHDAEAALDAVRRKFGSKAAQFGA
>Mature_447_residues
TMSAAPCAPHSEHDLVRHSYNGGMSTAPRLEAAKRDWGHDETGCTVLHIDMDAFYASLEVARNPGLKGKPVIIGTGPRAV
VSAASYEARRYGINSAMPAARAHQLCPNGVFLPVDMAYYRMMSHRIMHEVFLTVTDRFEQVSVDEGYMDVSTALLEWGRP
SAIGAWIRAQVAERFHVTCSVGIACNKLVAKMASTNAKPDGMLLIPAARSAEFVQMMPLRGIPGIGPSLEKRLNAWGVHS
VAELAQLDETALTRATGSPAAARGLWAASHGLDSRKITTVREEKSIGSEETLAEDTRDMRVVCGLLRSACDEVASTLRRK
GLVARTLTVKLRFADLSYQTRSFTMERPTDTAGVLYPECVRQLKVMLGLPASAESATPLPKTIRLAGMSTSSLSEAAATA
VQPSLDDMLEEAANARGQTSQARLHDAEAALDAVRRKFGSKAAQFGA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=340, Percent_Identity=26.7647058823529, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI7706681, Length=341, Percent_Identity=26.6862170087977, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI154350220, Length=285, Percent_Identity=27.719298245614, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI7705344, Length=112, Percent_Identity=38.3928571428571, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786425, Length=307, Percent_Identity=33.8762214983713, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1787432, Length=207, Percent_Identity=31.8840579710145, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=424, Percent_Identity=25.7075471698113, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17537959, Length=384, Percent_Identity=28.125, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=239, Percent_Identity=28.4518828451883, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=29.5774647887324, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=29.5774647887324, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI19923006, Length=295, Percent_Identity=23.3898305084746, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 48313; Mature: 48182

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50173 UMUC ; PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSAAPCAPHSEHDLVRHSYNGGMSTAPRLEAAKRDWGHDETGCTVLHIDMDAFYASLE
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHH
VARNPGLKGKPVIIGTGPRAVVSAASYEARRYGINSAMPAARAHQLCPNGVFLPVDMAYY
HHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEECHHHHHH
RMMSHRIMHEVFLTVTDRFEQVSVDEGYMDVSTALLEWGRPSAIGAWIRAQVAERFHVTC
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEE
SVGIACNKLVAKMASTNAKPDGMLLIPAARSAEFVQMMPLRGIPGIGPSLEKRLNAWGVH
EECHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCHH
SVAELAQLDETALTRATGSPAAARGLWAASHGLDSRKITTVREEKSIGSEETLAEDTRDM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHCCCCHHHHHHHHHHH
RVVCGLLRSACDEVASTLRRKGLVARTLTVKLRFADLSYQTRSFTMERPTDTAGVLYPEC
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHEEEECCCCCCCCCCHHHH
VRQLKVMLGLPASAESATPLPKTIRLAGMSTSSLSEAAATAVQPSLDDMLEEAANARGQT
HHHHHHHHCCCCCCCCCCCCCHHEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
SQARLHDAEAALDAVRRKFGSKAAQFGA
HHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
TMSAAPCAPHSEHDLVRHSYNGGMSTAPRLEAAKRDWGHDETGCTVLHIDMDAFYASLE
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHH
VARNPGLKGKPVIIGTGPRAVVSAASYEARRYGINSAMPAARAHQLCPNGVFLPVDMAYY
HHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEECHHHHHH
RMMSHRIMHEVFLTVTDRFEQVSVDEGYMDVSTALLEWGRPSAIGAWIRAQVAERFHVTC
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEE
SVGIACNKLVAKMASTNAKPDGMLLIPAARSAEFVQMMPLRGIPGIGPSLEKRLNAWGVH
EECHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCHH
SVAELAQLDETALTRATGSPAAARGLWAASHGLDSRKITTVREEKSIGSEETLAEDTRDM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHCCCCHHHHHHHHHHH
RVVCGLLRSACDEVASTLRRKGLVARTLTVKLRFADLSYQTRSFTMERPTDTAGVLYPEC
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHEEEECCCCCCCCCCHHHH
VRQLKVMLGLPASAESATPLPKTIRLAGMSTSSLSEAAATAVQPSLDDMLEEAANARGQT
HHHHHHHHCCCCCCCCCCCCCHHEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
SQARLHDAEAALDAVRRKFGSKAAQFGA
HHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA