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The map label for this gene is alr [H]

Identifier: 213692856

GI number: 213692856

Start: 2178863

End: 2180221

Strand: Reverse

Name: alr [H]

Synonym: Blon_1997

Alternate gene names: 213692856

Gene position: 2180221-2178863 (Counterclockwise)

Preceding gene: 213692858

Following gene: 213692855

Centisome position: 76.96

GC content: 67.99

Gene sequence:

>1359_bases
ATGAGCATGAACGCAGCACCGGAAATCGCATTCTCCTCCGAGCGGGGCAAAGCCAATTACGAGGCCGCCCGCCGGCAATA
CCCCGCGCAGGCCATCGTGAACCTCAAAACCATGCGCGACAACATGGCCCATCTGGTCTCCGTGGTGGGTGGCCCCACAT
CGGGCACGGCGGTGATGGGCGTGGTCAAGGCCGACGCATACGGCCATGGCCTGCTGCCCACCGCCCTGGCCGCGCTCGCC
GGCGGGGCCACATGGCTCGGCACCGCGCAATCGCATGAGGCGCTCCTGTTGCGCAGGCTTGGCATCGGCCCCGACCGGTG
CCATATCCTGACCTGGGTATACAACGGCGCCGCGGCGCCGTTCGATGATTTGATCGCCGCCGACATCGACGTGTCGGTCG
GCTCCCTGTCCGGCATCGAAGCGCTGGCCGCCGCCGCGCGCAGGCTCGGCAAGCCCGCCCGCGTGCATGTGAAGGTCGAT
TCCGGTTTTGGCCGCAACGGGTTCACTCCGGCCGGATTCGACGCCGCGCTCGCCGCGCTCGTGCCCCTCGCCAAGGAGGG
TGTGCTGCGCATCGTGGGCCAGTGGAGCCACCTCGCCGTGGCCGATTCGCCCGATGTGCCCGAATTCGTCGCCTCCACCG
ACCAGCAGATCGCAACGTTCAAGGACTTCACCAGGCGCATGGAGCTGGCCGGCATCCCGCCCGAGATCCGACATCTGGCC
AATACGGCGGCGACACTGGACCGACCCGAGATCCATTTCGAACTCACCCGCCCCGGCATCGGCCTGTACGGCTACGAACC
CGACCCCGCGATGGGCACCCCGCGCGACTGGCATCTGACCCCGGCCATGCGCCTGCAGGCGCAGCTCGGCACGGTCAAGG
ACGTGGAGGCGGGTCACGGCATCTCCTATGGCCGTACCTATCTGACCCCGGACAACACGTCCACCGCCATAGTGCCGCTG
GGGTACGCCGACGGCATCCACCGCTCCGCTTCGGGATTCGACATGGAGGGGGCCAAGCATGTGGAGAAGCCGGGAGGCCC
GGTGCGCATCATGACCGCCGAAGGCCCGAGACTGTACCGTGTGTGCGGTCGCGTGTGCATGGACCAGTTCATCGTGGACC
TGCACGGATCCGCCGCCGAACTCGGCGTTCACGAGGGCGACACGGTCGAACTGTTCGGCGCGGGACGCGGCGAGGATTAC
GTTGAGCCTACCGCCGACGATTGGGCCCGCGCCGCCGACACCATCAGCTACGAGATCTTCACCTGCCTGCGCAACCGCAT
CCCGCGCCTGTACGAGCAGGCCGCCGACGCGCTGCCCGCCGCCGACCTCGCCAAACTCGACCCGGCCACGCTGCTATAA

Upstream 100 bases:

>100_bases
GACTGCCCGGCGAAAACGGTGCCCGCCGTTCCGCACGCCGGGACGGCGTCATGCGGTCGAAACGACCGCACGTCATATTC
CCGCGCAACAATAGATATCC

Downstream 100 bases:

>100_bases
GGTGCATTACCGCCATACGGTGGCACCCCGTAATCCCTTCCTTCCCGAATATGTGCCACTGACATGTGCTGAGCGTCACA
TATTCGGGAAATCGGCCCCA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSMNAAPEIAFSSERGKANYEAARRQYPAQAIVNLKTMRDNMAHLVSVVGGPTSGTAVMGVVKADAYGHGLLPTALAALA
GGATWLGTAQSHEALLLRRLGIGPDRCHILTWVYNGAAAPFDDLIAADIDVSVGSLSGIEALAAAARRLGKPARVHVKVD
SGFGRNGFTPAGFDAALAALVPLAKEGVLRIVGQWSHLAVADSPDVPEFVASTDQQIATFKDFTRRMELAGIPPEIRHLA
NTAATLDRPEIHFELTRPGIGLYGYEPDPAMGTPRDWHLTPAMRLQAQLGTVKDVEAGHGISYGRTYLTPDNTSTAIVPL
GYADGIHRSASGFDMEGAKHVEKPGGPVRIMTAEGPRLYRVCGRVCMDQFIVDLHGSAAELGVHEGDTVELFGAGRGEDY
VEPTADDWARAADTISYEIFTCLRNRIPRLYEQAADALPAADLAKLDPATLL

Sequences:

>Translated_452_residues
MSMNAAPEIAFSSERGKANYEAARRQYPAQAIVNLKTMRDNMAHLVSVVGGPTSGTAVMGVVKADAYGHGLLPTALAALA
GGATWLGTAQSHEALLLRRLGIGPDRCHILTWVYNGAAAPFDDLIAADIDVSVGSLSGIEALAAAARRLGKPARVHVKVD
SGFGRNGFTPAGFDAALAALVPLAKEGVLRIVGQWSHLAVADSPDVPEFVASTDQQIATFKDFTRRMELAGIPPEIRHLA
NTAATLDRPEIHFELTRPGIGLYGYEPDPAMGTPRDWHLTPAMRLQAQLGTVKDVEAGHGISYGRTYLTPDNTSTAIVPL
GYADGIHRSASGFDMEGAKHVEKPGGPVRIMTAEGPRLYRVCGRVCMDQFIVDLHGSAAELGVHEGDTVELFGAGRGEDY
VEPTADDWARAADTISYEIFTCLRNRIPRLYEQAADALPAADLAKLDPATLL
>Mature_451_residues
SMNAAPEIAFSSERGKANYEAARRQYPAQAIVNLKTMRDNMAHLVSVVGGPTSGTAVMGVVKADAYGHGLLPTALAALAG
GATWLGTAQSHEALLLRRLGIGPDRCHILTWVYNGAAAPFDDLIAADIDVSVGSLSGIEALAAAARRLGKPARVHVKVDS
GFGRNGFTPAGFDAALAALVPLAKEGVLRIVGQWSHLAVADSPDVPEFVASTDQQIATFKDFTRRMELAGIPPEIRHLAN
TAATLDRPEIHFELTRPGIGLYGYEPDPAMGTPRDWHLTPAMRLQAQLGTVKDVEAGHGISYGRTYLTPDNTSTAIVPLG
YADGIHRSASGFDMEGAKHVEKPGGPVRIMTAEGPRLYRVCGRVCMDQFIVDLHGSAAELGVHEGDTVELFGAGRGEDYV
EPTADDWARAADTISYEIFTCLRNRIPRLYEQAADALPAADLAKLDPATLL

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=403, Percent_Identity=30.272952853598, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787439, Length=405, Percent_Identity=32.0987654320988, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 48122; Mature: 47991

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNAAPEIAFSSERGKANYEAARRQYPAQAIVNLKTMRDNMAHLVSVVGGPTSGTAVMG
CCCCCCCCEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VVKADAYGHGLLPTALAALAGGATWLGTAQSHEALLLRRLGIGPDRCHILTWVYNGAAAP
EEEECCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCC
FDDLIAADIDVSVGSLSGIEALAAAARRLGKPARVHVKVDSGFGRNGFTPAGFDAALAAL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
VPLAKEGVLRIVGQWSHLAVADSPDVPEFVASTDQQIATFKDFTRRMELAGIPPEIRHLA
HHHHHCCHHHHHCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
NTAATLDRPEIHFELTRPGIGLYGYEPDPAMGTPRDWHLTPAMRLQAQLGTVKDVEAGHG
HHHHHCCCCCEEEEEECCCCEECCCCCCCCCCCCCCEECCHHHHHHHHHCCCEECCCCCC
ISYGRTYLTPDNTSTAIVPLGYADGIHRSASGFDMEGAKHVEKPGGPVRIMTAEGPRLYR
CCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCHHHH
VCGRVCMDQFIVDLHGSAAELGVHEGDTVELFGAGRGEDYVEPTADDWARAADTISYEIF
HHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
TCLRNRIPRLYEQAADALPAADLAKLDPATLL
HHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCC
>Mature Secondary Structure 
SMNAAPEIAFSSERGKANYEAARRQYPAQAIVNLKTMRDNMAHLVSVVGGPTSGTAVMG
CCCCCCCEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VVKADAYGHGLLPTALAALAGGATWLGTAQSHEALLLRRLGIGPDRCHILTWVYNGAAAP
EEEECCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCC
FDDLIAADIDVSVGSLSGIEALAAAARRLGKPARVHVKVDSGFGRNGFTPAGFDAALAAL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
VPLAKEGVLRIVGQWSHLAVADSPDVPEFVASTDQQIATFKDFTRRMELAGIPPEIRHLA
HHHHHCCHHHHHCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
NTAATLDRPEIHFELTRPGIGLYGYEPDPAMGTPRDWHLTPAMRLQAQLGTVKDVEAGHG
HHHHHCCCCCEEEEEECCCCEECCCCCCCCCCCCCCEECCHHHHHHHHHCCCEECCCCCC
ISYGRTYLTPDNTSTAIVPLGYADGIHRSASGFDMEGAKHVEKPGGPVRIMTAEGPRLYR
CCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCHHHH
VCGRVCMDQFIVDLHGSAAELGVHEGDTVELFGAGRGEDYVEPTADDWARAADTISYEIF
HHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
TCLRNRIPRLYEQAADALPAADLAKLDPATLL
HHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA