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The map label for this gene is uvrX [H]

Identifier: 213692811

GI number: 213692811

Start: 2130369

End: 2132015

Strand: Reverse

Name: uvrX [H]

Synonym: Blon_1951

Alternate gene names: 213692811

Gene position: 2132015-2130369 (Counterclockwise)

Preceding gene: 213692821

Following gene: 213692810

Centisome position: 75.26

GC content: 59.74

Gene sequence:

>1647_bases
ATGGGCAGCGGAACGGTATCGACGCAACGCGAGCATACCTATATTGCCATTGATCTCAAGTCCTTCTATGCCTCGGTGGA
GTGCGCGGCGCGCGGACTCGACCCGTTGACCACGCATCTGGTGGTGGCCGATGAAACCCGCACCGATAAGACAATATGTT
TGGCGGTCTCACCCTCGCTGAAGAACTATGGCATTCCCGGTCGTGCGCGGCTATTCGAGGTAAAACAGCGCCTGAATGGA
GTCAACATCGAGCGCGCGGTCCATGCTCCCGGCGGCCGATTAATCGGGGAGTCCTGCGATGCGCGCGACCTGGAACGCTC
GCCGAGACTCAAAGCCTCGATGGTCATCGCCAAGCCGCGCATGGCGCACTATTTGGAGGTCAGCGGGCAGGTATATGGCA
TCTACCTCAAATACGCCGCACCCGAGCACATCCATGTCTACTCGATTGACGAGGTGTTCATCGACGTCACGCCATATCTG
CGCTCGCTGGGTATGGGGCCGCATGCCATGGCGCGAACCATCGTGCGCGAAATTCTCGATGAAACCGGCATCACCGCCAC
TGCCGGCATCGGCTCCAACATGTATCTGGCCAAAGTCGCCATGGATATCGTCGCCAAGCACATGCCCGCGGATCGCGACG
GCGTGCGCATCGCCGAATTGGATGAAATGTCATACCGCCGGCTGCTCTGGAACCATCGTCCCCTCACCGATTTCTGGCGG
GTAGGGCGTGGATATGCCCGAAAACTCGAGCGCGCCGGATTGACGACCATGGGGGATATCGCCCGATGCTCGGTGGGTCG
TGCTTCGGATTACTACAACGAAGACCTGCTGTATCGCATGTTCGGTGTCAATGCCGAACTGCTCATCGACCATGCGTGGG
GCTGGGAGCCGTGCGAAATCGCAGATATCCGATCCTATGAGCCAGGTGCGCACAGCATCAGCAGCGGGCAGGTGCTCACC
GGGCCCGCCGATTGGCATACGGCTCGGCTGATCGCCAAGGAGATGGCCGATGCGCTCGCCCTCGATTTGGTCGATAAGGG
GGTGATGACGAATCGGCTGACACTGGCGGTCGGCTATGACATTGGCAGTCTCGATGCTTCGAAGCTTGATTCATGCGCAG
ACCGGGCGATGAGGCGTGCCGCCGAACGCGCGGCAAAGACCTATCAAGGGCCGGTGACCGTTGACCGTTTCGGTCGTCGG
GTGCCTAAGTCGGCCGTGGGGTCGATTGGATTGGGTGATTTTACGTCGTCTGCCGCACGTATTCGCGAGGCGATGACCAT
GCTGTACGAGCGTATTGTGGATGCGCGGTTGCTGGTGCGTCGACTCACGGTTGTTGCCGATGATGTGGCCACGCCCAAAG
AACTGGCGGCGGGCAAACGCTATGAGCAGCTTGATTTGTTCGGTGATGATGGCGATATGCGATATGACTGTGATAGCACG
GAATCCGGTGGCGACGGAAGCGGGCGTATGCCGGCTTGTGGGGACGATGCCGCCGCACAGACGTTGGCTCGAGAGCATGA
TATTCAGCGTGCGCTGCTGGATGTGAAACGTAAATTCGGCCGCAACGCCGTCATCAAAGCCATGGATATGGAAGACGGCG
CCACCGGTCAGGACCGCAACCGTCAGATCGGAGGCCATCGCGCATGA

Upstream 100 bases:

>100_bases
GCGTCGACTTCGGCAGCTTCGAACAGGCATGTTGCATCGAACAAATGTTCGACCGTATTGATATGCTGGCCGGGACGGCG
GTGGTAAGGAGGTGATGGCG

Downstream 100 bases:

>100_bases
CCCTGCAAGAGACCCGGGCATACGACGACATCATCAACCTGCCCCATCACCAGTCGCGCAAGCATCCGCACATGTCCCGC
CACCAGCGGGCCGCGCAGTT

Product: UMUC domain protein DNA-repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MGSGTVSTQREHTYIAIDLKSFYASVECAARGLDPLTTHLVVADETRTDKTICLAVSPSLKNYGIPGRARLFEVKQRLNG
VNIERAVHAPGGRLIGESCDARDLERSPRLKASMVIAKPRMAHYLEVSGQVYGIYLKYAAPEHIHVYSIDEVFIDVTPYL
RSLGMGPHAMARTIVREILDETGITATAGIGSNMYLAKVAMDIVAKHMPADRDGVRIAELDEMSYRRLLWNHRPLTDFWR
VGRGYARKLERAGLTTMGDIARCSVGRASDYYNEDLLYRMFGVNAELLIDHAWGWEPCEIADIRSYEPGAHSISSGQVLT
GPADWHTARLIAKEMADALALDLVDKGVMTNRLTLAVGYDIGSLDASKLDSCADRAMRRAAERAAKTYQGPVTVDRFGRR
VPKSAVGSIGLGDFTSSAARIREAMTMLYERIVDARLLVRRLTVVADDVATPKELAAGKRYEQLDLFGDDGDMRYDCDST
ESGGDGSGRMPACGDDAAAQTLAREHDIQRALLDVKRKFGRNAVIKAMDMEDGATGQDRNRQIGGHRA

Sequences:

>Translated_548_residues
MGSGTVSTQREHTYIAIDLKSFYASVECAARGLDPLTTHLVVADETRTDKTICLAVSPSLKNYGIPGRARLFEVKQRLNG
VNIERAVHAPGGRLIGESCDARDLERSPRLKASMVIAKPRMAHYLEVSGQVYGIYLKYAAPEHIHVYSIDEVFIDVTPYL
RSLGMGPHAMARTIVREILDETGITATAGIGSNMYLAKVAMDIVAKHMPADRDGVRIAELDEMSYRRLLWNHRPLTDFWR
VGRGYARKLERAGLTTMGDIARCSVGRASDYYNEDLLYRMFGVNAELLIDHAWGWEPCEIADIRSYEPGAHSISSGQVLT
GPADWHTARLIAKEMADALALDLVDKGVMTNRLTLAVGYDIGSLDASKLDSCADRAMRRAAERAAKTYQGPVTVDRFGRR
VPKSAVGSIGLGDFTSSAARIREAMTMLYERIVDARLLVRRLTVVADDVATPKELAAGKRYEQLDLFGDDGDMRYDCDST
ESGGDGSGRMPACGDDAAAQTLAREHDIQRALLDVKRKFGRNAVIKAMDMEDGATGQDRNRQIGGHRA
>Mature_547_residues
GSGTVSTQREHTYIAIDLKSFYASVECAARGLDPLTTHLVVADETRTDKTICLAVSPSLKNYGIPGRARLFEVKQRLNGV
NIERAVHAPGGRLIGESCDARDLERSPRLKASMVIAKPRMAHYLEVSGQVYGIYLKYAAPEHIHVYSIDEVFIDVTPYLR
SLGMGPHAMARTIVREILDETGITATAGIGSNMYLAKVAMDIVAKHMPADRDGVRIAELDEMSYRRLLWNHRPLTDFWRV
GRGYARKLERAGLTTMGDIARCSVGRASDYYNEDLLYRMFGVNAELLIDHAWGWEPCEIADIRSYEPGAHSISSGQVLTG
PADWHTARLIAKEMADALALDLVDKGVMTNRLTLAVGYDIGSLDASKLDSCADRAMRRAAERAAKTYQGPVTVDRFGRRV
PKSAVGSIGLGDFTSSAARIREAMTMLYERIVDARLLVRRLTVVADDVATPKELAAGKRYEQLDLFGDDGDMRYDCDSTE
SGGDGSGRMPACGDDAAAQTLAREHDIQRALLDVKRKFGRNAVIKAMDMEDGATGQDRNRQIGGHRA

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 60305; Mature: 60174

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGTVSTQREHTYIAIDLKSFYASVECAARGLDPLTTHLVVADETRTDKTICLAVSPSL
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCEEEEEECCCH
KNYGIPGRARLFEVKQRLNGVNIERAVHAPGGRLIGESCDARDLERSPRLKASMVIAKPR
HHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCHHHCCCCCCEEEEEEECCH
MAHYLEVSGQVYGIYLKYAAPEHIHVYSIDEVFIDVTPYLRSLGMGPHAMARTIVREILD
HHHHEEECCEEEEEEEEECCCCEEEEEEHHHHEEEHHHHHHHCCCCHHHHHHHHHHHHHH
ETGITATAGIGSNMYLAKVAMDIVAKHMPADRDGVRIAELDEMSYRRLLWNHRPLTDFWR
HCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHH
VGRGYARKLERAGLTTMGDIARCSVGRASDYYNEDLLYRMFGVNAELLIDHAWGWEPCEI
HCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCC
ADIRSYEPGAHSISSGQVLTGPADWHTARLIAKEMADALALDLVDKGVMTNRLTLAVGYD
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
IGSLDASKLDSCADRAMRRAAERAAKTYQGPVTVDRFGRRVPKSAVGSIGLGDFTSSAAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCCCCHHHHHHHH
IREAMTMLYERIVDARLLVRRLTVVADDVATPKELAAGKRYEQLDLFGDDGDMRYDCDST
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCEEECCCCC
ESGGDGSGRMPACGDDAAAQTLAREHDIQRALLDVKRKFGRNAVIKAMDMEDGATGQDRN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
RQIGGHRA
CCCCCCCC
>Mature Secondary Structure 
GSGTVSTQREHTYIAIDLKSFYASVECAARGLDPLTTHLVVADETRTDKTICLAVSPSL
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCEEEEEECCCH
KNYGIPGRARLFEVKQRLNGVNIERAVHAPGGRLIGESCDARDLERSPRLKASMVIAKPR
HHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCHHHCCCCCCEEEEEEECCH
MAHYLEVSGQVYGIYLKYAAPEHIHVYSIDEVFIDVTPYLRSLGMGPHAMARTIVREILD
HHHHEEECCEEEEEEEEECCCCEEEEEEHHHHEEEHHHHHHHCCCCHHHHHHHHHHHHHH
ETGITATAGIGSNMYLAKVAMDIVAKHMPADRDGVRIAELDEMSYRRLLWNHRPLTDFWR
HCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHH
VGRGYARKLERAGLTTMGDIARCSVGRASDYYNEDLLYRMFGVNAELLIDHAWGWEPCEI
HCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCC
ADIRSYEPGAHSISSGQVLTGPADWHTARLIAKEMADALALDLVDKGVMTNRLTLAVGYD
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
IGSLDASKLDSCADRAMRRAAERAAKTYQGPVTVDRFGRRVPKSAVGSIGLGDFTSSAAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHCCCCCCHHHHHHHH
IREAMTMLYERIVDARLLVRRLTVVADDVATPKELAAGKRYEQLDLFGDDGDMRYDCDST
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCEEECCCCC
ESGGDGSGRMPACGDDAAAQTLAREHDIQRALLDVKRKFGRNAVIKAMDMEDGATGQDRN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
RQIGGHRA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]