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The map label for this gene is dapL [H]

Identifier: 213692799

GI number: 213692799

Start: 2115756

End: 2116946

Strand: Reverse

Name: dapL [H]

Synonym: Blon_1937

Alternate gene names: 213692799

Gene position: 2116946-2115756 (Counterclockwise)

Preceding gene: 213692801

Following gene: 213692798

Centisome position: 74.73

GC content: 63.73

Gene sequence:

>1191_bases
ATGCCGACGTCGAACGCGGCTCTGATTTCTCGACGGGCGGCTAGTCTGCCCGGCAATCCTTTTGCTGAGGCGGACGCACG
CGCTGCAGCAGCCGTCGCCGCTGGCAAGGATATCATCGACTTGAGCAAAGGGAATCCCGATGGCTGGCCGCCATCCTTTG
TACAGGACGCGCTTTCTCACGCTTCCCACAATCCTTCCCTGTTCCGGTACCCGCCATTTGATGGGCTTCCGGAATATCTG
AATGCGATTGCCGGCTGGTATTCGCGCCAGCACAACGTCACCGTGGACCCCGCCACCCAGCTGCTGGCGACTTCCGGCTC
GTCCGTCGGCATAACCACCGTCATCCAGGCGCTGGTCGATCCGGGAGATACGGTGGTGGCGGTCGACCCGTATTACCCGC
AGTACGAGGGCTCAACAGTAGTGGCCGGTGGCCAGTTCGAGGCGATTCCCGCTGACCCGAGCCGCGGATTCCTGCCCGAC
TTGGATGCGGTGGACCCAGCGCTATGGACTCGCGCCAAACTGCTGATTCTGAACTATCCCAACAATCCGACCGGCGCGGC
CGCAACACCCGAACTGTATGAGACGGCCATGCGCCTGGCCAAGCAATACGGATTCATCGTACTTAACGATTTCGCCTATG
CGGGGCTCGAATTCGGCGACGTGCGCTCGCTGAGCCTGCTGGAGACTCCGGGCGCGCTGGACGTGGCGCTGGAACTTGGC
TCGCTGTCCAAGATGTATATGGTGGCCGGCTGGCGCGGTGGATTCGTGGCGGGCAACGCCGAAGTCCTCTCTGCCGTCAA
AGCCGTACACCGGCAGACTGCGGTGTTGGCTTCCAGCGTTATTCAGCAGGCCGGTGCGGTGGCGCTGGAATCCGATCAGA
GCACGGTGAAGCTGCTGGCTGTGCAATATCAGCATCGTTTTGAAGTGGTGCGTGACGGGTTTACCCAGGCTGGTCTGCCG
GTGGCCGAGGCCCAAGGCGGCCTGTTCGCGTGGGCGCGCGTGCCGGTGCGGTGGCATGGCGATTCCGCCGCATTCGTGGA
TTGGCTGCTCAACACGGCCGGCGTGGCGCTGATGCCGGGGGTCTGCTTCGGTCAGGCGGGCGAAGGCTGGGTGCGCATCA
GTCTGCTCAAGCACACCGCCGAGTTGTTCCAGGCCGTGGCCCGCGCCGATCGTGCGCTGCGAAGCGCGTGA

Upstream 100 bases:

>100_bases
AACATTTTTGGATGCGACATATAGCGAATAGCGGCGTGTCGGTTCCGGCGTTTCAGGCTACAAGCCGGCACGCCGGCAAT
AGTCGAAGGGGGAGGGCGAC

Downstream 100 bases:

>100_bases
TTCAATATTGGGCAAAATGCGGCAGCCCATACCATTTCACACGCGTTCAGGCAGCGCGGCCGACGCCATTGCCGCGCGGT
GGTTTAGGATGAGGCAATGC

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPTSNAALISRRAASLPGNPFAEADARAAAAVAAGKDIIDLSKGNPDGWPPSFVQDALSHASHNPSLFRYPPFDGLPEYL
NAIAGWYSRQHNVTVDPATQLLATSGSSVGITTVIQALVDPGDTVVAVDPYYPQYEGSTVVAGGQFEAIPADPSRGFLPD
LDAVDPALWTRAKLLILNYPNNPTGAAATPELYETAMRLAKQYGFIVLNDFAYAGLEFGDVRSLSLLETPGALDVALELG
SLSKMYMVAGWRGGFVAGNAEVLSAVKAVHRQTAVLASSVIQQAGAVALESDQSTVKLLAVQYQHRFEVVRDGFTQAGLP
VAEAQGGLFAWARVPVRWHGDSAAFVDWLLNTAGVALMPGVCFGQAGEGWVRISLLKHTAELFQAVARADRALRSA

Sequences:

>Translated_396_residues
MPTSNAALISRRAASLPGNPFAEADARAAAAVAAGKDIIDLSKGNPDGWPPSFVQDALSHASHNPSLFRYPPFDGLPEYL
NAIAGWYSRQHNVTVDPATQLLATSGSSVGITTVIQALVDPGDTVVAVDPYYPQYEGSTVVAGGQFEAIPADPSRGFLPD
LDAVDPALWTRAKLLILNYPNNPTGAAATPELYETAMRLAKQYGFIVLNDFAYAGLEFGDVRSLSLLETPGALDVALELG
SLSKMYMVAGWRGGFVAGNAEVLSAVKAVHRQTAVLASSVIQQAGAVALESDQSTVKLLAVQYQHRFEVVRDGFTQAGLP
VAEAQGGLFAWARVPVRWHGDSAAFVDWLLNTAGVALMPGVCFGQAGEGWVRISLLKHTAELFQAVARADRALRSA
>Mature_395_residues
PTSNAALISRRAASLPGNPFAEADARAAAAVAAGKDIIDLSKGNPDGWPPSFVQDALSHASHNPSLFRYPPFDGLPEYLN
AIAGWYSRQHNVTVDPATQLLATSGSSVGITTVIQALVDPGDTVVAVDPYYPQYEGSTVVAGGQFEAIPADPSRGFLPDL
DAVDPALWTRAKLLILNYPNNPTGAAATPELYETAMRLAKQYGFIVLNDFAYAGLEFGDVRSLSLLETPGALDVALELGS
LSKMYMVAGWRGGFVAGNAEVLSAVKAVHRQTAVLASSVIQQAGAVALESDQSTVKLLAVQYQHRFEVVRDGFTQAGLPV
AEAQGGLFAWARVPVRWHGDSAAFVDWLLNTAGVALMPGVCFGQAGEGWVRISLLKHTAELFQAVARADRALRSA

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=422, Percent_Identity=26.7772511848341, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI169881279, Length=422, Percent_Identity=26.7772511848341, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI56713256, Length=403, Percent_Identity=24.317617866005, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI56713254, Length=403, Percent_Identity=24.317617866005, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI169881281, Length=421, Percent_Identity=22.8028503562945, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7705897, Length=329, Percent_Identity=25.8358662613982, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI33469970, Length=329, Percent_Identity=25.8358662613982, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1788722, Length=376, Percent_Identity=33.7765957446808, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=24.0997229916898, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788627, Length=381, Percent_Identity=25.4593175853018, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788332, Length=239, Percent_Identity=29.7071129707113, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787909, Length=328, Percent_Identity=23.780487804878, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=299, Percent_Identity=27.7591973244147, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=270, Percent_Identity=28.1481481481481, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=380, Percent_Identity=21.8421052631579, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=23.4375, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=25.4545454545455, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320317, Length=417, Percent_Identity=24.220623501199, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=23.7726098191214, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=23.7726098191214, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=23.7726098191214, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=23.7726098191214, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 41932; Mature: 41801

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSNAALISRRAASLPGNPFAEADARAAAAVAAGKDIIDLSKGNPDGWPPSFVQDALSH
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHH
ASHNPSLFRYPPFDGLPEYLNAIAGWYSRQHNVTVDPATQLLATSGSSVGITTVIQALVD
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHCCCCCCCHHHHHHHHHC
PGDTVVAVDPYYPQYEGSTVVAGGQFEAIPADPSRGFLPDLDAVDPALWTRAKLLILNYP
CCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCCCHHHHCCEEEEEEECC
NNPTGAAATPELYETAMRLAKQYGFIVLNDFAYAGLEFGDVRSLSLLETPGALDVALELG
CCCCCCCCCHHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCCEEEECCCCCCEEEEECC
SLSKMYMVAGWRGGFVAGNAEVLSAVKAVHRQTAVLASSVIQQAGAVALESDQSTVKLLA
CCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
VQYQHRFEVVRDGFTQAGLPVAEAQGGLFAWARVPVRWHGDSAAFVDWLLNTAGVALMPG
HHHHHHHHHHHCCHHHCCCCHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCHHHCCC
VCFGQAGEGWVRISLLKHTAELFQAVARADRALRSA
CEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTSNAALISRRAASLPGNPFAEADARAAAAVAAGKDIIDLSKGNPDGWPPSFVQDALSH
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHH
ASHNPSLFRYPPFDGLPEYLNAIAGWYSRQHNVTVDPATQLLATSGSSVGITTVIQALVD
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHCCCCCCCHHHHHHHHHC
PGDTVVAVDPYYPQYEGSTVVAGGQFEAIPADPSRGFLPDLDAVDPALWTRAKLLILNYP
CCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCCCHHHHCCEEEEEEECC
NNPTGAAATPELYETAMRLAKQYGFIVLNDFAYAGLEFGDVRSLSLLETPGALDVALELG
CCCCCCCCCHHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCCEEEECCCCCCEEEEECC
SLSKMYMVAGWRGGFVAGNAEVLSAVKAVHRQTAVLASSVIQQAGAVALESDQSTVKLLA
CCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
VQYQHRFEVVRDGFTQAGLPVAEAQGGLFAWARVPVRWHGDSAAFVDWLLNTAGVALMPG
HHHHHHHHHHHCCHHHCCCCHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCHHHCCC
VCFGQAGEGWVRISLLKHTAELFQAVARADRALRSA
CEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA