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The map label for this gene is tlyA [H]

Identifier: 213692730

GI number: 213692730

Start: 2033100

End: 2033930

Strand: Reverse

Name: tlyA [H]

Synonym: Blon_1864

Alternate gene names: 213692730

Gene position: 2033930-2033100 (Counterclockwise)

Preceding gene: 213692731

Following gene: 213692728

Centisome position: 71.8

GC content: 60.29

Gene sequence:

>831_bases
ATGGTGGCTCCATGCCGAGCCACCCCGTTGGTAGATGGTGGGTCGGAAGGAAGGTATATGACCAAGCAACATATCGATTC
CGCAACCCCACTTGACCGACTCGACATGATGCTCGTGGCTTCGGGACTGGTCGAATCGCGGGCCAAAGCGCAGCGACTCA
TCAAAGCCGGGCATGTGCGCGTGGACGGCGAGACCATCACCAAGCCATCGTTCATGGTCAAAGCCGGGCACAGCGAACTC
GCCGTGGATAAGGGCGACGACTACGTCTCCCGAGGCGCTTACAAACTCTTGGGCGCGTTCGAAACCTTTGCCGGCAATGG
CCTTACCGGGCCGGAAGGCTTGGAATGTCTGGACATCGGTGCCTCCACCGGTGGCTTCACCGACGTACTGTTGCGTGGGG
GAGCGGCCAAGGTCGTGGCGCTCGACGTCGGCCACGGCCAGCTCGACCCGCGCATCGCCAATGACGAGCACGTCATCGAA
ATGAGCGGCGTCAACATTCGCGAAGTTGAGGCCGACGACCTGCCTTACCGGCCGGCGATGATCGTCTCCGATGTCTCCTT
TATTTCCCTGACCTATGTGATTCCGGTAATCGCGCGCATCGCGGCTCCCGGTGCGCAGATTGTGTTACTGGTCAAACCGC
AGTTCGAGGTCGGCCGGGCAGGACTCGGCAAACACGGCATCGTTGAAGATCCGGCATTGCGGGAGCGGGCATTACACGAC
GTGGTCGCCTGTGCTGAACAGCACGGACTTGACGTGGTGGCCACTGCCGATAGTCCCATCATCGGCACCCACGGTAATGA
GGAATACCTGCTTTACGCTGTCTTGAGATGA

Upstream 100 bases:

>100_bases
TCGCAACGTGCTGGAATCGTTACAACACGAGCTTGATAACAGCCGCAGCTAGCAGAGGTGATTCATTCTCCCGCCAGCGG
AAGATGACGTGAAGTGCTGG

Downstream 100 bases:

>100_bases
ATGCGTTGGCAGTCTCCGTTCACCAGCAGCACGCTGGAGGTACGGTCGATGCCTATTGCGGTGGCGCACGTGGCGCTTTC
CACCGCACTGCCGTTGCGTA

Product: hemolysin A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVAPCRATPLVDGGSEGRYMTKQHIDSATPLDRLDMMLVASGLVESRAKAQRLIKAGHVRVDGETITKPSFMVKAGHSEL
AVDKGDDYVSRGAYKLLGAFETFAGNGLTGPEGLECLDIGASTGGFTDVLLRGGAAKVVALDVGHGQLDPRIANDEHVIE
MSGVNIREVEADDLPYRPAMIVSDVSFISLTYVIPVIARIAAPGAQIVLLVKPQFEVGRAGLGKHGIVEDPALRERALHD
VVACAEQHGLDVVATADSPIIGTHGNEEYLLYAVLR

Sequences:

>Translated_276_residues
MVAPCRATPLVDGGSEGRYMTKQHIDSATPLDRLDMMLVASGLVESRAKAQRLIKAGHVRVDGETITKPSFMVKAGHSEL
AVDKGDDYVSRGAYKLLGAFETFAGNGLTGPEGLECLDIGASTGGFTDVLLRGGAAKVVALDVGHGQLDPRIANDEHVIE
MSGVNIREVEADDLPYRPAMIVSDVSFISLTYVIPVIARIAAPGAQIVLLVKPQFEVGRAGLGKHGIVEDPALRERALHD
VVACAEQHGLDVVATADSPIIGTHGNEEYLLYAVLR
>Mature_276_residues
MVAPCRATPLVDGGSEGRYMTKQHIDSATPLDRLDMMLVASGLVESRAKAQRLIKAGHVRVDGETITKPSFMVKAGHSEL
AVDKGDDYVSRGAYKLLGAFETFAGNGLTGPEGLECLDIGASTGGFTDVLLRGGAAKVVALDVGHGQLDPRIANDEHVIE
MSGVNIREVEADDLPYRPAMIVSDVSFISLTYVIPVIARIAAPGAQIVLLVKPQFEVGRAGLGKHGIVEDPALRERALHD
VVACAEQHGLDVVATADSPIIGTHGNEEYLLYAVLR

Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 29272; Mature: 29272

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPCRATPLVDGGSEGRYMTKQHIDSATPLDRLDMMLVASGLVESRAKAQRLIKAGHVR
CCCCCCCCCCCCCCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VDGETITKPSFMVKAGHSELAVDKGDDYVSRGAYKLLGAFETFAGNGLTGPEGLECLDIG
ECCCEECCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
ASTGGFTDVLLRGGAAKVVALDVGHGQLDPRIANDEHVIEMSGVNIREVEADDLPYRPAM
CCCCCHHHHHCCCCCEEEEEEECCCCCCCCEECCCCEEEEECCCEEEEECCCCCCCCCCC
IVSDVSFISLTYVIPVIARIAAPGAQIVLLVKPQFEVGRAGLGKHGIVEDPALRERALHD
EEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHH
VVACAEQHGLDVVATADSPIIGTHGNEEYLLYAVLR
HHHHHHHCCCEEEEECCCCEEECCCCCCEEEEEEEC
>Mature Secondary Structure
MVAPCRATPLVDGGSEGRYMTKQHIDSATPLDRLDMMLVASGLVESRAKAQRLIKAGHVR
CCCCCCCCCCCCCCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VDGETITKPSFMVKAGHSELAVDKGDDYVSRGAYKLLGAFETFAGNGLTGPEGLECLDIG
ECCCEECCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
ASTGGFTDVLLRGGAAKVVALDVGHGQLDPRIANDEHVIEMSGVNIREVEADDLPYRPAM
CCCCCHHHHHCCCCCEEEEEEECCCCCCCCEECCCCEEEEECCCEEEEECCCCCCCCCCC
IVSDVSFISLTYVIPVIARIAAPGAQIVLLVKPQFEVGRAGLGKHGIVEDPALRERALHD
EEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHH
VVACAEQHGLDVVATADSPIIGTHGNEEYLLYAVLR
HHHHHHHCCCEEEEECCCCEEECCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730486 [H]