Click here to switch to the map view.

The map label for this gene is phoP [H]

Identifier: 213692629

GI number: 213692629

Start: 1936690

End: 1937412

Strand: Direct

Name: phoP [H]

Synonym: Blon_1762

Alternate gene names: 213692629

Gene position: 1936690-1937412 (Clockwise)

Preceding gene: 213692628

Following gene: 213692630

Centisome position: 68.37

GC content: 65.01

Gene sequence:

>723_bases
ATGCTCAATACCACAGCGCGTCAGAATACGACACCGCGCACGGTGCTGGTGGTCGAGGACGAGCCCACGCTCGCCACGGC
CATTGCCCAGCGCATCACCGCTGAAGGATGGACCGCTCGCGTGGCCGGGGACGGCGCTTCCGCCGTCCAGGCCGCGTCCC
AGCTACGCCCCGATCTGGTAATCATGGACATCATGCTGCCGGTCATGGATGGTCTTGAGGCCACCAAACGCATCGTCGCC
GAACGTCCGGTGCCGGTGCTGATTCTCACCGCGCGTGATGACGAGGCCGACAAGGTCATCGGTCTGGGAGCGGGCGCCGA
TGATTACATGACCAAACCGTTCTCCATGCGCGAGCTCATCGCCCGCTGCAAGGCGCTGCTGCGCCGCGTGGAGCGTGCGA
AGGTCATCGCCAAGAATTCGGAGAACGAGAAGCTGCTCGACTTCGGTTCGATAGTCATCGACCCGGCACAGCGCATCGTC
ACCGTGAACGGCGAGCAGGTGCATCTGACCCCCACCGAGTTCGATCTGCTGGCCACACTGGCCCGCCGCCCGAAGTCGGT
GCTCACCCGCGAAAAGCTGCTCGAAGAGGTCTGGGACTGGGTCGACGCATCCGGCACCCGCACCGTCGACAGCCATGTCA
AGGCGCTGCGCCATAAGCTCGGCGCCGATACCATCCGCACCGTGCATGGCGTGGGCTACGCTTTCGAGCCGCCGACCGCG
TGA

Upstream 100 bases:

>100_bases
GTCCGTTCTCGGCGAAGATCACCGTTCCGGCTCTGGGAGTTGTATTCTTGAAGCCGGAAGACTGAACTGGTCAACAGGCT
GAAAGGTAACCGGTTTATTT

Downstream 100 bases:

>100_bases
TGGCATCCAAAAAACAACAGCAATCCCGGCTTGATGCGATGAAACATCGCATCAAGCCGGTTGATTTGTTCTCCTCTCTG
AAGCTGGAACTCAGCGCACT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLNTTARQNTTPRTVLVVEDEPTLATAIAQRITAEGWTARVAGDGASAVQAASQLRPDLVIMDIMLPVMDGLEATKRIVA
ERPVPVLILTARDDEADKVIGLGAGADDYMTKPFSMRELIARCKALLRRVERAKVIAKNSENEKLLDFGSIVIDPAQRIV
TVNGEQVHLTPTEFDLLATLARRPKSVLTREKLLEEVWDWVDASGTRTVDSHVKALRHKLGADTIRTVHGVGYAFEPPTA

Sequences:

>Translated_240_residues
MLNTTARQNTTPRTVLVVEDEPTLATAIAQRITAEGWTARVAGDGASAVQAASQLRPDLVIMDIMLPVMDGLEATKRIVA
ERPVPVLILTARDDEADKVIGLGAGADDYMTKPFSMRELIARCKALLRRVERAKVIAKNSENEKLLDFGSIVIDPAQRIV
TVNGEQVHLTPTEFDLLATLARRPKSVLTREKLLEEVWDWVDASGTRTVDSHVKALRHKLGADTIRTVHGVGYAFEPPTA
>Mature_240_residues
MLNTTARQNTTPRTVLVVEDEPTLATAIAQRITAEGWTARVAGDGASAVQAASQLRPDLVIMDIMLPVMDGLEATKRIVA
ERPVPVLILTARDDEADKVIGLGAGADDYMTKPFSMRELIARCKALLRRVERAKVIAKNSENEKLLDFGSIVIDPAQRIV
TVNGEQVHLTPTEFDLLATLARRPKSVLTREKLLEEVWDWVDASGTRTVDSHVKALRHKLGADTIRTVHGVGYAFEPPTA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=36.480686695279, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=38.5650224215247, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=38.695652173913, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=37.3873873873874, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=34.5291479820628, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=36.8421052631579, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.6812227074236, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=33.9285714285714, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.4410480349345, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=33.7777777777778, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=33.0396475770925, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.0924369747899, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=34.2592592592593, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787487, Length=150, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26282; Mature: 26282

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTTARQNTTPRTVLVVEDEPTLATAIAQRITAEGWTARVAGDGASAVQAASQLRPDLV
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHH
IMDIMLPVMDGLEATKRIVAERPVPVLILTARDDEADKVIGLGAGADDYMTKPFSMRELI
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHCCCCCHHHHH
ARCKALLRRVERAKVIAKNSENEKLLDFGSIVIDPAQRIVTVNGEQVHLTPTEFDLLATL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEECCCCEEEEECCCEEEECCCHHHHHHHH
ARRPKSVLTREKLLEEVWDWVDASGTRTVDSHVKALRHKLGADTIRTVHGVGYAFEPPTA
HHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLNTTARQNTTPRTVLVVEDEPTLATAIAQRITAEGWTARVAGDGASAVQAASQLRPDLV
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHH
IMDIMLPVMDGLEATKRIVAERPVPVLILTARDDEADKVIGLGAGADDYMTKPFSMRELI
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHCCCCCHHHHH
ARCKALLRRVERAKVIAKNSENEKLLDFGSIVIDPAQRIVTVNGEQVHLTPTEFDLLATL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEECCCCEEEEECCCEEEECCCHHHHHHHH
ARRPKSVLTREKLLEEVWDWVDASGTRTVDSHVKALRHKLGADTIRTVHGVGYAFEPPTA
HHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]