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The map label for this gene is nudF [H]

Identifier: 213692608

GI number: 213692608

Start: 1910601

End: 1911275

Strand: Reverse

Name: nudF [H]

Synonym: Blon_1741

Alternate gene names: 213692608

Gene position: 1911275-1910601 (Counterclockwise)

Preceding gene: 213692609

Following gene: 213692607

Centisome position: 67.47

GC content: 60.74

Gene sequence:

>675_bases
ATGTTTGGGGGAAGCAAGCAGGAACAACTGGAGCATCGGCTCGACCATAAGCTGAACGCCTCCTCGGACGGCATCGACAT
GGACGTGCCCGCCAAAGTGATCAGTAGCGAAACCGTTTATACCGGGCGCATCTTCCACGTGGACGACATGCGCATCGCTC
TGACCGACAAGCAGGGCAAGGAACACGAGATCGGCCGCCAGGTGCTGCGTCACGCCCCCTGTGTGGTCATGCTCGTGCAC
GACATGTCCACCGACCGTTACCTCATCGAACGCGAATACCGTGCCGGATCGGACATGTTCGCCTACGGGCTTCCCGCCGG
TCTCATGGACGAGGGCGAGGACATCATGGACGCGGCCCTGAGGGAACTGGCCGAGGAAACCGGCGTGGTGCCGGACCGTG
ACACCATGGGTGTTGACTTCGTGGGCGATTTCTACTCGTCCGAAGGCATGACCGACGAACTGGCCCACATCATGGTGTTG
CATTTGGGCCCGTTCAGGCGGGAGCAGCGCCATTTCGACGCGGACGAGCACGTGGAATCCGCGTGGATTCCGTGGAGCGA
CCTTGCCGCCACGCGCATCACCTCATCCAATTCGATGATCGCCATCCAGCATGAGGCGTTACGCAGACTCATCGCCAGGA
ACTCCGACAAAGACAAGCCGTCGCTGTTCTCCTGA

Upstream 100 bases:

>100_bases
GTTCCACGACACGACCGATCCATGGACGCTGTCCATTACCGCGCATCGAGATTAAGACGCTATAGTGACGTGGCGAAAAC
GATTTTTCCGAGGAGATGAC

Downstream 100 bases:

>100_bases
CGTTCAACTCCCCGGCACATCAGTGACACAAGAAAGTGGGATACTGAAAACTATGCAGATCAGACCTGGATCAATGTATC
CGCTGGGCGCCAGCTATGAC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MFGGSKQEQLEHRLDHKLNASSDGIDMDVPAKVISSETVYTGRIFHVDDMRIALTDKQGKEHEIGRQVLRHAPCVVMLVH
DMSTDRYLIEREYRAGSDMFAYGLPAGLMDEGEDIMDAALRELAEETGVVPDRDTMGVDFVGDFYSSEGMTDELAHIMVL
HLGPFRREQRHFDADEHVESAWIPWSDLAATRITSSNSMIAIQHEALRRLIARNSDKDKPSLFS

Sequences:

>Translated_224_residues
MFGGSKQEQLEHRLDHKLNASSDGIDMDVPAKVISSETVYTGRIFHVDDMRIALTDKQGKEHEIGRQVLRHAPCVVMLVH
DMSTDRYLIEREYRAGSDMFAYGLPAGLMDEGEDIMDAALRELAEETGVVPDRDTMGVDFVGDFYSSEGMTDELAHIMVL
HLGPFRREQRHFDADEHVESAWIPWSDLAATRITSSNSMIAIQHEALRRLIARNSDKDKPSLFS
>Mature_224_residues
MFGGSKQEQLEHRLDHKLNASSDGIDMDVPAKVISSETVYTGRIFHVDDMRIALTDKQGKEHEIGRQVLRHAPCVVMLVH
DMSTDRYLIEREYRAGSDMFAYGLPAGLMDEGEDIMDAALRELAEETGVVPDRDTMGVDFVGDFYSSEGMTDELAHIMVL
HLGPFRREQRHFDADEHVESAWIPWSDLAATRITSSNSMIAIQHEALRRLIARNSDKDKPSLFS

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 25306; Mature: 25306

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGGSKQEQLEHRLDHKLNASSDGIDMDVPAKVISSETVYTGRIFHVDDMRIALTDKQGK
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEEEEEECCEEEEEECCCCC
EHEIGRQVLRHAPCVVMLVHDMSTDRYLIEREYRAGSDMFAYGLPAGLMDEGEDIMDAAL
HHHHHHHHHHHCCEEEEEEECCCCCCEEEHHHHCCCCCEEECCCCCCCCCCCHHHHHHHH
RELAEETGVVPDRDTMGVDFVGDFYSSEGMTDELAHIMVLHLGPFRREQRHFDADEHVES
HHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHH
AWIPWSDLAATRITSSNSMIAIQHEALRRLIARNSDKDKPSLFS
CCCCHHHHHHHEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFGGSKQEQLEHRLDHKLNASSDGIDMDVPAKVISSETVYTGRIFHVDDMRIALTDKQGK
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEEEEEECCEEEEEECCCCC
EHEIGRQVLRHAPCVVMLVHDMSTDRYLIEREYRAGSDMFAYGLPAGLMDEGEDIMDAAL
HHHHHHHHHHHCCEEEEEEECCCCCCEEEHHHHCCCCCEEECCCCCCCCCCCHHHHHHHH
RELAEETGVVPDRDTMGVDFVGDFYSSEGMTDELAHIMVLHLGPFRREQRHFDADEHVES
HHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHH
AWIPWSDLAATRITSSNSMIAIQHEALRRLIARNSDKDKPSLFS
CCCCHHHHHHHEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]