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The map label for this gene is ycnB [H]

Identifier: 213692518

GI number: 213692518

Start: 1802716

End: 1804767

Strand: Reverse

Name: ycnB [H]

Synonym: Blon_1650

Alternate gene names: 213692518

Gene position: 1804767-1802716 (Counterclockwise)

Preceding gene: 213692521

Following gene: 213692517

Centisome position: 63.71

GC content: 60.48

Gene sequence:

>2052_bases
GTGACCTCACAGAAAAACGCGGAACTCGGGTCCGCCACCAGTTCCGTAAAGCCTATTGATCCGCACACCCGATTCATCGT
CGTGGGCGTGATCGTCGTCGGCTCGTTCATCGCGCTGCTCAACCAGACCGTCATGTCACCGGCCTTGCCGGCACTGATGC
GTGATTTCAATATCACCACCGGCACCGTGCAGTGGGTGACCAGCGTCTACATGCTGGTCTCGGGCATCATGGTGCCGATT
TCAGGCTATCTGATTGATAAATTCTCCACCCGAAAGCTCTTCGCCGGAGCTCTTGCCACTTTCATGGTCGGCACACTGCT
GTGTGCCGTCGCGCCGAATTTCATGCTGTTGCTCGTCGGGCGCATACTGCAATCCGCCGGCTCCGGCGTGCTGTTGCCAT
TGGTCGCCGTAGTGCCGATGCTCGTCTATCCGCCGGATAAGCGCGGCACCGCCATGGGACTGGCCGGTATCGTCATGGCC
GCCGGCCCGGCTATCGGCCCGGTTGTCGGTGGTCTGGTGATTGACAGTTTCGGATGGCGCCCGATGTTCATTGGCATCGC
AGTCGTGGCACTGGTCATCCTTGTCGGAGGCACGATGATGCTCAAGAACGTCAGCGAGTTGAAGAACCCAAAGCTCAACA
TCCTGTCCGTGATCCTTTCGACCATCGCGTTCGGTGGCCTGCTTTATGGCTTCTCGTCCGCTTCCACGATGGTATGGAGC
AGTCCGGTCGTCATTATCTCAATCGTCGTTGGTCTTGTGGCCTTCGTCGCATTCGTATACAAGCAAGTCAAGCTCGATGA
GCCATTGTTGCGCGTTGATACCCTTGCCACCCGCAACTTCCGCAACTCCGTGATTCTGGTCACTCTGATCAACGCCGCAG
TCGCCGCAACCAACGTGACGTTGCCTATCTTCATCCAGAATGTGCTCGGCCAATCCGCCACCGTCACCGGCATGGTCATG
CTGCCCGCCGCGGCGGTCGGCATCATCCTGAGTCCGGTCGCCGGCGCCGCATTCGACAAATTCGGCCCTCGCGGCGTGGG
CATCGGCGGCCTTGCGCTCATGACCATCTCTCTTGGTCTTCTCGGCACCATCAACACCAGGACATCAGTGCTGTTTGTCG
CCGTGTTCTGCGCATTGCAGGCATCCGGTCAGGCTATCGCCAACATGCCGATCAACACTTGGGGCGTCAACGCTTTGCCG
AACGACATGATCGCCCATGGAAACGCCATCGCCAACACAGGCCGCCAGATCGCGGCAGCCATTGCGACCTCGCTTCTGGT
CACCGCAGAAACATCCATGACCGCCTCGCACATGTCCCAGGGTGTGAAGTCCGCCACGGCCAGCGGCATCGCGTTCTCCT
ACCTGCTGTGCGCCGCCATCTCGCTGGTCGCCCTGATCATCTGCATCTTCACCGTCACCAGCCGTGCCAAGGAGAAGGCC
GCACGCAACGCCAAGGCCTCCGAGGCGCAAGCCTCCGCCGAAGTCGCGGCCGAAACCACTGAAGGCCAGCCCGCCGAGCA
TCACTACGCCGGCGCATACGTGGCCCCCGCCGCCTCCCTGTTCAAGCAGGCCCAGGAACAGTCCATCGGCGGAATCATGG
ACGATCAGCCCTACAGCTGCCTGGACAGCGATGACATCACGCATGTGGTGCGCGAGTTCATCCGCCTCAACGTCTCCAGC
CTTCCCGTGGTGAACGGCGATGGCAGGCTCGTCGGCTTCGTCAGCGACGGCGATGTCATGAAATCGATTGCCACCTATGA
ATCCCGTACGGTTTCCACCGGCACCGGTTCGACGATGGTGGTGTTCGACGACGAAACCGTGACCTCCAAGGTGCAGGCGC
TCTCCGGCAAGAAGGTGATGGACATCGCCACGCGCAAGGTCGTTGCCGCCACGCCCGACCAGCATGTCGGAGAGGTGGCC
CGAATCCTCGCCAAGAAGCAGTTCAAGAAACTGCCGGTGGTGGATGGTGATGGCAGACTCGTCGGTGTGATCCGCCGTAA
GTCCGTGATGGAACATGCCTTCGATGCGCTGTTCCCAAAGGATGATCGGTGA

Upstream 100 bases:

>100_bases
CGGCTTTTCCTTTACGTCCGGACTCATCGGTGTCCTCGCGTCTTGACACAAGCATGGGGCCGGATCGCCACACATGACGT
TACCAACAGAAGGAAATGCT

Downstream 100 bases:

>100_bases
TTAGGCGCCATCATCGCTGAATAGAATGAATGGAACATGAGGCTTCCCTTCCGTGGAAAACACTCTTGTGCTTTGCTTCG
TTTCCTGCTATGTGTGAAAA

Product: drug resistance transporter, EmrB/QacA subfamily

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 682

Protein sequence:

>683_residues
MTSQKNAELGSATSSVKPIDPHTRFIVVGVIVVGSFIALLNQTVMSPALPALMRDFNITTGTVQWVTSVYMLVSGIMVPI
SGYLIDKFSTRKLFAGALATFMVGTLLCAVAPNFMLLLVGRILQSAGSGVLLPLVAVVPMLVYPPDKRGTAMGLAGIVMA
AGPAIGPVVGGLVIDSFGWRPMFIGIAVVALVILVGGTMMLKNVSELKNPKLNILSVILSTIAFGGLLYGFSSASTMVWS
SPVVIISIVVGLVAFVAFVYKQVKLDEPLLRVDTLATRNFRNSVILVTLINAAVAATNVTLPIFIQNVLGQSATVTGMVM
LPAAAVGIILSPVAGAAFDKFGPRGVGIGGLALMTISLGLLGTINTRTSVLFVAVFCALQASGQAIANMPINTWGVNALP
NDMIAHGNAIANTGRQIAAAIATSLLVTAETSMTASHMSQGVKSATASGIAFSYLLCAAISLVALIICIFTVTSRAKEKA
ARNAKASEAQASAEVAAETTEGQPAEHHYAGAYVAPAASLFKQAQEQSIGGIMDDQPYSCLDSDDITHVVREFIRLNVSS
LPVVNGDGRLVGFVSDGDVMKSIATYESRTVSTGTGSTMVVFDDETVTSKVQALSGKKVMDIATRKVVAATPDQHVGEVA
RILAKKQFKKLPVVDGDGRLVGVIRRKSVMEHAFDALFPKDDR

Sequences:

>Translated_683_residues
MTSQKNAELGSATSSVKPIDPHTRFIVVGVIVVGSFIALLNQTVMSPALPALMRDFNITTGTVQWVTSVYMLVSGIMVPI
SGYLIDKFSTRKLFAGALATFMVGTLLCAVAPNFMLLLVGRILQSAGSGVLLPLVAVVPMLVYPPDKRGTAMGLAGIVMA
AGPAIGPVVGGLVIDSFGWRPMFIGIAVVALVILVGGTMMLKNVSELKNPKLNILSVILSTIAFGGLLYGFSSASTMVWS
SPVVIISIVVGLVAFVAFVYKQVKLDEPLLRVDTLATRNFRNSVILVTLINAAVAATNVTLPIFIQNVLGQSATVTGMVM
LPAAAVGIILSPVAGAAFDKFGPRGVGIGGLALMTISLGLLGTINTRTSVLFVAVFCALQASGQAIANMPINTWGVNALP
NDMIAHGNAIANTGRQIAAAIATSLLVTAETSMTASHMSQGVKSATASGIAFSYLLCAAISLVALIICIFTVTSRAKEKA
ARNAKASEAQASAEVAAETTEGQPAEHHYAGAYVAPAASLFKQAQEQSIGGIMDDQPYSCLDSDDITHVVREFIRLNVSS
LPVVNGDGRLVGFVSDGDVMKSIATYESRTVSTGTGSTMVVFDDETVTSKVQALSGKKVMDIATRKVVAATPDQHVGEVA
RILAKKQFKKLPVVDGDGRLVGVIRRKSVMEHAFDALFPKDDR
>Mature_682_residues
TSQKNAELGSATSSVKPIDPHTRFIVVGVIVVGSFIALLNQTVMSPALPALMRDFNITTGTVQWVTSVYMLVSGIMVPIS
GYLIDKFSTRKLFAGALATFMVGTLLCAVAPNFMLLLVGRILQSAGSGVLLPLVAVVPMLVYPPDKRGTAMGLAGIVMAA
GPAIGPVVGGLVIDSFGWRPMFIGIAVVALVILVGGTMMLKNVSELKNPKLNILSVILSTIAFGGLLYGFSSASTMVWSS
PVVIISIVVGLVAFVAFVYKQVKLDEPLLRVDTLATRNFRNSVILVTLINAAVAATNVTLPIFIQNVLGQSATVTGMVML
PAAAVGIILSPVAGAAFDKFGPRGVGIGGLALMTISLGLLGTINTRTSVLFVAVFCALQASGQAIANMPINTWGVNALPN
DMIAHGNAIANTGRQIAAAIATSLLVTAETSMTASHMSQGVKSATASGIAFSYLLCAAISLVALIICIFTVTSRAKEKAA
RNAKASEAQASAEVAAETTEGQPAEHHYAGAYVAPAASLFKQAQEQSIGGIMDDQPYSCLDSDDITHVVREFIRLNVSSL
PVVNGDGRLVGFVSDGDVMKSIATYESRTVSTGTGSTMVVFDDETVTSKVQALSGKKVMDIATRKVVAATPDQHVGEVAR
ILAKKQFKKLPVVDGDGRLVGVIRRKSVMEHAFDALFPKDDR

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=442, Percent_Identity=24.2081447963801, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1788710, Length=437, Percent_Identity=23.5697940503432, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081983, Length=399, Percent_Identity=24.3107769423559, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790195, Length=330, Percent_Identity=23.6363636363636, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788392, Length=123, Percent_Identity=29.2682926829268, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=320, Percent_Identity=23.4375, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322071, Length=211, Percent_Identity=25.5924170616114, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319770, Length=272, Percent_Identity=26.1029411764706, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 71401; Mature: 71270

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQKNAELGSATSSVKPIDPHTRFIVVGVIVVGSFIALLNQTVMSPALPALMRDFNITT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTVQWVTSVYMLVSGIMVPISGYLIDKFSTRKLFAGALATFMVGTLLCAVAPNFMLLLVG
HHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILQSAGSGVLLPLVAVVPMLVYPPDKRGTAMGLAGIVMAAGPAIGPVVGGLVIDSFGWR
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
PMFIGIAVVALVILVGGTMMLKNVSELKNPKLNILSVILSTIAFGGLLYGFSSASTMVWS
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
SPVVIISIVVGLVAFVAFVYKQVKLDEPLLRVDTLATRNFRNSVILVTLINAAVAATNVT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCH
LPIFIQNVLGQSATVTGMVMLPAAAVGIILSPVAGAAFDKFGPRGVGIGGLALMTISLGL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LGTINTRTSVLFVAVFCALQASGQAIANMPINTWGVNALPNDMIAHGNAIANTGRQIAAA
HCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH
IATSLLVTAETSMTASHMSQGVKSATASGIAFSYLLCAAISLVALIICIFTVTSRAKEKA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARNAKASEAQASAEVAAETTEGQPAEHHYAGAYVAPAASLFKQAQEQSIGGIMDDQPYSC
HHCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LDSDDITHVVREFIRLNVSSLPVVNGDGRLVGFVSDGDVMKSIATYESRTVSTGTGSTMV
CCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCHHHHHHHHHCCCEEECCCCCEEE
VFDDETVTSKVQALSGKKVMDIATRKVVAATPDQHVGEVARILAKKQFKKLPVVDGDGRL
EECCCHHHHHHHHHCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
VGVIRRKSVMEHAFDALFPKDDR
EHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSQKNAELGSATSSVKPIDPHTRFIVVGVIVVGSFIALLNQTVMSPALPALMRDFNITT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTVQWVTSVYMLVSGIMVPISGYLIDKFSTRKLFAGALATFMVGTLLCAVAPNFMLLLVG
HHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILQSAGSGVLLPLVAVVPMLVYPPDKRGTAMGLAGIVMAAGPAIGPVVGGLVIDSFGWR
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
PMFIGIAVVALVILVGGTMMLKNVSELKNPKLNILSVILSTIAFGGLLYGFSSASTMVWS
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
SPVVIISIVVGLVAFVAFVYKQVKLDEPLLRVDTLATRNFRNSVILVTLINAAVAATNVT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCH
LPIFIQNVLGQSATVTGMVMLPAAAVGIILSPVAGAAFDKFGPRGVGIGGLALMTISLGL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LGTINTRTSVLFVAVFCALQASGQAIANMPINTWGVNALPNDMIAHGNAIANTGRQIAAA
HCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH
IATSLLVTAETSMTASHMSQGVKSATASGIAFSYLLCAAISLVALIICIFTVTSRAKEKA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARNAKASEAQASAEVAAETTEGQPAEHHYAGAYVAPAASLFKQAQEQSIGGIMDDQPYSC
HHCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LDSDDITHVVREFIRLNVSSLPVVNGDGRLVGFVSDGDVMKSIATYESRTVSTGTGSTMV
CCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCHHHHHHHHHCCCEEECCCCCEEE
VFDDETVTSKVQALSGKKVMDIATRKVVAATPDQHVGEVARILAKKQFKKLPVVDGDGRL
EECCCHHHHHHHHHCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
VGVIRRKSVMEHAFDALFPKDDR
EHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]