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The map label for this gene is cpx [H]

Identifier: 213692489

GI number: 213692489

Start: 1770202

End: 1771566

Strand: Direct

Name: cpx [H]

Synonym: Blon_1618

Alternate gene names: 213692489

Gene position: 1770202-1771566 (Clockwise)

Preceding gene: 213692488

Following gene: 213692491

Centisome position: 62.49

GC content: 63.0

Gene sequence:

>1365_bases
ATGTCAGAGAAGAAAACCAAGAATTCCGTATCCTTTGAGGCGCTGTCTTCGCTGGACGCGCCAGTATCCTTCTGGAAGGG
CATTCCGTTCGGCCTGCAGCATGTGATGGCCATGTTCGTGGCGAACCTCGCCCCGATCTTCATCGTCGCCTCGGCCGCGA
AAATGACCCCGGCCCAATCGGCCACCATCATCCAGGCCGGCCTTCTGGTTGCGGGCCTAGGCACCTGCCTGCAACTGTAC
GGCGCGTGGCTCATCGGCTCGCGTCTGCCGATGGTCACCGGCATCTCCTTCACCTACGTGGCGGCCGCCGTGGCGATCTG
CGCGGACAAGGGCTATGGCGCAGTGGTCGGCGCGGTAATGGTCGGCGGTCTGCTGGAACTCGTGCTGGGTTTGACGGCCA
AGTATTGGCGTCGGTTCGTGCCGCCCATCGTCTCCGCCATCGTGGTCACGTCGATCGGCTTCTCGCTGCTCAACGTGGGT
GCCACGAGCTTCGGCGGCGGCAGCGGAGCCAAGGACTTCGGTTCCTGGCAAAACCTAACGCTCGGGCTTATATCTTTGGT
CGCCTGCCTGGCGTTCCAGCTGTTGATGAAGGGCACGGCCAAGCAGCTGTCCGTGCTGTTCGGCCTGGTAGTCGGCTATG
TGGCGGCCATCTGCATGGGCAAGGTCGATTTCTCCGGTTTCCAGAACCTCGCCATCGTGTCCGTGCCGCAGTTCATGCCG
TTCAAGCCTGAGTTCGACTGGGGTTCGATCATCTCCATCGGCCTGCTCTACGTCGTCTCCTCGGTCGAGGTGCTGGGTGA
CACCGCCGCGCTGACCAAGGTGGGCCTGAACCGTACTCCCACCGAACGCGAGACCGCGGGCGCCATCGCCGGCGACGGCC
TGATCTCCACCGTATCCGGCCTGTTCGGATGCCTGCCGCTGACCTCGTTCGCGCAGAACATCGGATTGGTGGCCATGACC
AAGGTCGTCAACCGCAAGGTGATTCTCTCCGGCGGACTGATTCTGGTGCTGGCGAGCTTCGTGCCGGCCATCGCCGAGGT
GTTCAACTCGCTGCCACAGGCGGTGCTCGGCGGCTGCACGATCATGATGTTCGGCAACATCATTCTTTCGGGCTTCCAGA
TGATCGCCGAAGCGGGCTTCACGCAGCGCAACATCACGCTTGCGGCGCTTTCGCTGACCATCGGCATCGGCTTCACCCAG
GTGAGCGACATCTTCGCGCAGTTCCCGACACTGTTCCAACAAATCTTCGCCTCGAACTGCATCGCCGTGGCGTTCGTGGT
GGCCGTGATCCTGAACGCCGTGCTGCCCAGCGAGGAGCACTTCCTCTCCGCGCCCAAGGAGGCACCGGCCGCGGACGCCG
AGTGA

Upstream 100 bases:

>100_bases
TCGTCGAGTCCATGAATCCCGAGACCGGCGAAATCACATTTAGGCACTAAGCACATTGCCTGCTCCCGCCGGCGGGAGCA
ACAGAGAGAAGAAGAGAATC

Downstream 100 bases:

>100_bases
TAACAACGCGACATATCAGCTGCGCATAATCACATGATGATGCCCTATCGTCTTGCAGGATGATAGGGCATCATTGATTT
TGAGAGAGACTACAAGTTGA

Product: Xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSEKKTKNSVSFEALSSLDAPVSFWKGIPFGLQHVMAMFVANLAPIFIVASAAKMTPAQSATIIQAGLLVAGLGTCLQLY
GAWLIGSRLPMVTGISFTYVAAAVAICADKGYGAVVGAVMVGGLLELVLGLTAKYWRRFVPPIVSAIVVTSIGFSLLNVG
ATSFGGGSGAKDFGSWQNLTLGLISLVACLAFQLLMKGTAKQLSVLFGLVVGYVAAICMGKVDFSGFQNLAIVSVPQFMP
FKPEFDWGSIISIGLLYVVSSVEVLGDTAALTKVGLNRTPTERETAGAIAGDGLISTVSGLFGCLPLTSFAQNIGLVAMT
KVVNRKVILSGGLILVLASFVPAIAEVFNSLPQAVLGGCTIMMFGNIILSGFQMIAEAGFTQRNITLAALSLTIGIGFTQ
VSDIFAQFPTLFQQIFASNCIAVAFVVAVILNAVLPSEEHFLSAPKEAPAADAE

Sequences:

>Translated_454_residues
MSEKKTKNSVSFEALSSLDAPVSFWKGIPFGLQHVMAMFVANLAPIFIVASAAKMTPAQSATIIQAGLLVAGLGTCLQLY
GAWLIGSRLPMVTGISFTYVAAAVAICADKGYGAVVGAVMVGGLLELVLGLTAKYWRRFVPPIVSAIVVTSIGFSLLNVG
ATSFGGGSGAKDFGSWQNLTLGLISLVACLAFQLLMKGTAKQLSVLFGLVVGYVAAICMGKVDFSGFQNLAIVSVPQFMP
FKPEFDWGSIISIGLLYVVSSVEVLGDTAALTKVGLNRTPTERETAGAIAGDGLISTVSGLFGCLPLTSFAQNIGLVAMT
KVVNRKVILSGGLILVLASFVPAIAEVFNSLPQAVLGGCTIMMFGNIILSGFQMIAEAGFTQRNITLAALSLTIGIGFTQ
VSDIFAQFPTLFQQIFASNCIAVAFVVAVILNAVLPSEEHFLSAPKEAPAADAE
>Mature_453_residues
SEKKTKNSVSFEALSSLDAPVSFWKGIPFGLQHVMAMFVANLAPIFIVASAAKMTPAQSATIIQAGLLVAGLGTCLQLYG
AWLIGSRLPMVTGISFTYVAAAVAICADKGYGAVVGAVMVGGLLELVLGLTAKYWRRFVPPIVSAIVVTSIGFSLLNVGA
TSFGGGSGAKDFGSWQNLTLGLISLVACLAFQLLMKGTAKQLSVLFGLVVGYVAAICMGKVDFSGFQNLAIVSVPQFMPF
KPEFDWGSIISIGLLYVVSSVEVLGDTAALTKVGLNRTPTERETAGAIAGDGLISTVSGLFGCLPLTSFAQNIGLVAMTK
VVNRKVILSGGLILVLASFVPAIAEVFNSLPQAVLGGCTIMMFGNIILSGFQMIAEAGFTQRNITLAALSLTIGIGFTQV
SDIFAQFPTLFQQIFASNCIAVAFVVAVILNAVLPSEEHFLSAPKEAPAADAE

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082178, Length=454, Percent_Identity=30.8370044052863, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87082181, Length=439, Percent_Identity=29.8405466970387, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1790087, Length=428, Percent_Identity=29.6728971962617, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI87081818, Length=417, Percent_Identity=28.0575539568345, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788843, Length=387, Percent_Identity=26.8733850129199, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47232; Mature: 47101

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SEKKTKNSVSFEALSSLDAPVSFWKGIPFGLQHVMAMFVANLAPIFIVASAAKMTPAQS
CCCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH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HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842; 8162194 [H]