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The map label for this gene is aquIMA [H]

Identifier: 213692399

GI number: 213692399

Start: 1680554

End: 1681759

Strand: Direct

Name: aquIMA [H]

Synonym: Blon_1526

Alternate gene names: 213692399

Gene position: 1680554-1681759 (Clockwise)

Preceding gene: 213692398

Following gene: 213692400

Centisome position: 59.33

GC content: 59.04

Gene sequence:

>1206_bases
ATGAGCACGATACGCTACATCAGCCTGTTCAGCGGGATCGAAGCCGCCACCGTCGCATGGCGCCAGCTCGGGTGGAAGCC
AATCGCATACGCGGAAATCGAGCCATTTCCCAAAGCCGTGCTCAGACAACACTATCCGGAAGTACCAGATTTAGGAGATA
TGACCAAAGTTGACTGGAAACAATACCACCATGCGGCAGATGTCGTTGTGGGAGGAAGCCCCTGCCAAGCCTTCTCGATC
GCCGGCCTCAGGAAGGCTTTGGACGATCCACGCGGCCAGCTCATGCTCGAATATCTCCGAGCTTGCGCAGAGATTGATCC
GGAATGGATCGTCTGGGAGAACGTGCCCGGAGTACTGTCGGCTGAACACGGACGGGCTTTCCAATCGCTCCTTGAAGCCG
TGGCCGAACTCTGGCCTGATGGCGGGGCGGCATGGCGAGTGCTGGACGCTCAGTTCTTCGGTGTGGCCCAACGACGCGAG
CGTGTGTTCCTTGTCATCAACACTCGAGACTGGCGACGTGCCGCCCCGGTTCTTTTTGAGCGCGAAAGCCTGTGCTGGGA
TTCTGCGTCGAGCCGAGAGAAGAGGGAAACCCTTACCGGTGGAACTGCGAACGTCATTGGAAACGCAGATTCACACGTTG
GAGAATGCCTGACACCCGGTGAGAGCCAGGCACGCCGCGTGTATGCGGCTGACGGCGTGATGCCGACGTTGAACGCGCGT
GAGCATGGCGGGCAGAACCAGCATGCGGTCATGCTGGACTTCCACCAGCAGGACGGCAGGTTCCAGGCGTCGAACCATCC
AGACGTGTCGAACACGCTCACCAGCCACATGGGAACCGGTGGGAACAACGTTCCACTTGTGAAAGCGTTCAAATGGAATC
AAGGGGAACGCTCGCGCAGTCTGGCGATCGGTGATGTGAGTCCGACATTGAGCACCGACCATAATCCAGCCGTCTACGAG
ATAGCGGGAAACATCATCGGTCGCGGCCCAATGAACGGCGGATACCAGCTTGGTGTTGCCGACCCGGACGAAAACGGCGC
TTTCACATTGACTTCCACCGATAGACATGCGGTGGCTGGAATCGAGAGAGAGAGAGAAGTGATGTGCCGGGCGGACAGCC
AGGCGAACGCCGCATTGGACTCCGACCTCGCGCCGACCTTGATGGCGCACTCCGCGAAGGACGCGCCGATCATATACCCA
TCATGA

Upstream 100 bases:

>100_bases
CCCATCCACTCGTCAGGACGGGGCACACAACTTCAACAAGCAAAGGGAAACCAATGAGCGACAACCTCAACCACATCAAC
GCGCGCATCGGAGGTGAGGC

Downstream 100 bases:

>100_bases
CAAGCAACGGAGATGACGTGTTCCCCGCGCTGTGCGCCACTGACGGAAGCAAACGGTTCATCGACAACCAGTCCATCAAC
GGTGGGCGACTACTGATCGA

Product: DNA-cytosine methyltransferase

Products: NA

Alternate protein names: M.AquI subunit alpha; M.AquiA; Cytosine-specific methyltransferase AquI subunit alpha [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSTIRYISLFSGIEAATVAWRQLGWKPIAYAEIEPFPKAVLRQHYPEVPDLGDMTKVDWKQYHHAADVVVGGSPCQAFSI
AGLRKALDDPRGQLMLEYLRACAEIDPEWIVWENVPGVLSAEHGRAFQSLLEAVAELWPDGGAAWRVLDAQFFGVAQRRE
RVFLVINTRDWRRAAPVLFERESLCWDSASSREKRETLTGGTANVIGNADSHVGECLTPGESQARRVYAADGVMPTLNAR
EHGGQNQHAVMLDFHQQDGRFQASNHPDVSNTLTSHMGTGGNNVPLVKAFKWNQGERSRSLAIGDVSPTLSTDHNPAVYE
IAGNIIGRGPMNGGYQLGVADPDENGAFTLTSTDRHAVAGIEREREVMCRADSQANAALDSDLAPTLMAHSAKDAPIIYP
S

Sequences:

>Translated_401_residues
MSTIRYISLFSGIEAATVAWRQLGWKPIAYAEIEPFPKAVLRQHYPEVPDLGDMTKVDWKQYHHAADVVVGGSPCQAFSI
AGLRKALDDPRGQLMLEYLRACAEIDPEWIVWENVPGVLSAEHGRAFQSLLEAVAELWPDGGAAWRVLDAQFFGVAQRRE
RVFLVINTRDWRRAAPVLFERESLCWDSASSREKRETLTGGTANVIGNADSHVGECLTPGESQARRVYAADGVMPTLNAR
EHGGQNQHAVMLDFHQQDGRFQASNHPDVSNTLTSHMGTGGNNVPLVKAFKWNQGERSRSLAIGDVSPTLSTDHNPAVYE
IAGNIIGRGPMNGGYQLGVADPDENGAFTLTSTDRHAVAGIEREREVMCRADSQANAALDSDLAPTLMAHSAKDAPIIYP
S
>Mature_400_residues
STIRYISLFSGIEAATVAWRQLGWKPIAYAEIEPFPKAVLRQHYPEVPDLGDMTKVDWKQYHHAADVVVGGSPCQAFSIA
GLRKALDDPRGQLMLEYLRACAEIDPEWIVWENVPGVLSAEHGRAFQSLLEAVAELWPDGGAAWRVLDAQFFGVAQRRER
VFLVINTRDWRRAAPVLFERESLCWDSASSREKRETLTGGTANVIGNADSHVGECLTPGESQARRVYAADGVMPTLNARE
HGGQNQHAVMLDFHQQDGRFQASNHPDVSNTLTSHMGTGGNNVPLVKAFKWNQGERSRSLAIGDVSPTLSTDHNPAVYEI
AGNIIGRGPMNGGYQLGVADPDENGAFTLTSTDRHAVAGIEREREVMCRADSQANAALDSDLAPTLMAHSAKDAPIIYPS

Specific function: This methylase recognizes the double-stranded sequence CYCGRG, causes specific methylation on C-1 on both strands, and protects the DNA from cleavage by the AquI endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 43909; Mature: 43777

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00094 C5_MTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIRYISLFSGIEAATVAWRQLGWKPIAYAEIEPFPKAVLRQHYPEVPDLGDMTKVDWK
CCCEEEEHHHCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHH
QYHHAADVVVGGSPCQAFSIAGLRKALDDPRGQLMLEYLRACAEIDPEWIVWENVPGVLS
HHHHHHCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEE
AEHGRAFQSLLEAVAELWPDGGAAWRVLDAQFFGVAQRRERVFLVINTRDWRRAAPVLFE
CCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCEEEEEEECCCHHHHCCEEEC
RESLCWDSASSREKRETLTGGTANVIGNADSHVGECLTPGESQARRVYAADGVMPTLNAR
CHHHCCCCCCCHHHHHHHCCCCCEECCCCCCHHHHCCCCCCHHHCEEEECCCCCCCCCCH
EHGGQNQHAVMLDFHQQDGRFQASNHPDVSNTLTSHMGTGGNNVPLVKAFKWNQGERSRS
HCCCCCCEEEEEEEECCCCEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCE
LAIGDVSPTLSTDHNPAVYEIAGNIIGRGPMNGGYQLGVADPDENGAFTLTSTDRHAVAG
EEEECCCCCCCCCCCCEEEEEECCCEECCCCCCCEEEECCCCCCCCEEEEECCCCHHHHC
IEREREVMCRADSQANAALDSDLAPTLMAHSAKDAPIIYPS
CCHHHHHHHCCCCCCCHHHCCCCCHHHHHCCCCCCCEECCC
>Mature Secondary Structure 
STIRYISLFSGIEAATVAWRQLGWKPIAYAEIEPFPKAVLRQHYPEVPDLGDMTKVDWK
CCEEEEHHHCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHH
QYHHAADVVVGGSPCQAFSIAGLRKALDDPRGQLMLEYLRACAEIDPEWIVWENVPGVLS
HHHHHHCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEE
AEHGRAFQSLLEAVAELWPDGGAAWRVLDAQFFGVAQRRERVFLVINTRDWRRAAPVLFE
CCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCEEEEEEECCCHHHHCCEEEC
RESLCWDSASSREKRETLTGGTANVIGNADSHVGECLTPGESQARRVYAADGVMPTLNAR
CHHHCCCCCCCHHHHHHHCCCCCEECCCCCCHHHHCCCCCCHHHCEEEECCCCCCCCCCH
EHGGQNQHAVMLDFHQQDGRFQASNHPDVSNTLTSHMGTGGNNVPLVKAFKWNQGERSRS
HCCCCCCEEEEEEEECCCCEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCE
LAIGDVSPTLSTDHNPAVYEIAGNIIGRGPMNGGYQLGVADPDENGAFTLTSTDRHAVAG
EEEECCCCCCCCCCCCEEEEEECCCEECCCCCCCEEEECCCCCCCCEEEEECCCCHHHHC
IEREREVMCRADSQANAALDSDLAPTLMAHSAKDAPIIYPS
CCHHHHHHHCCCCCCCHHHCCCCCHHHHHCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2104605 [H]