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The map label for this gene is gltC [H]

Identifier: 213692318

GI number: 213692318

Start: 1601102

End: 1602025

Strand: Direct

Name: gltC [H]

Synonym: Blon_1443

Alternate gene names: 213692318

Gene position: 1601102-1602025 (Clockwise)

Preceding gene: 213692317

Following gene: 213692333

Centisome position: 56.52

GC content: 59.2

Gene sequence:

>924_bases
ATGACACTGCTGCAGCTGAAATACATCGTCAAGATCGTCGAGTGCGGCTCGATGAACGAGGCCTCCCATGCCCTGTACGT
CTCCCAGCCGGCCCTGAGCTCGTCGGTCAAGGAATTGGAGAACGAGCTGGGCATCGAGATCTTCACCCGCTCCTCGCAGG
GCATCGCCCTGACCGTGGACGGCGCGGAATTCCTGACCTACGCCCGCCAGGTGCTCGACCAGGCCGACCTGCTCGAAGAG
CGCTACAAGCACGCCAAACCGCGCAAGCAGCTGTGCCAGGTCTCCACCCAGCACTACATGTTCGCCGTCGAGACGTTCGT
GGAGATGATCAGCTCCATCAAGTCCGACGAATACGAGTTCACCATCCGCGAGACCCGCACGCGCGACATCATCAACCAAG
TCGCCAACATGCAGTCCGAAATCGGCATCATCTACCTGTCCGATTTCAACAAGGACGTGATCGGCAAACTCCTGCGCGAG
AAGCACCTCGAATTCCACCCGCTCTTCCGCGCGCCGCTGCACGTGTTCATCTCGCGCAACAACCCGCTGGCCGCCAAGAA
GGTCATCACCATGGAGGACCTGAAACCTTACCCGTTCATCCAGTACGAGCAGGGCGAGGAAGGCTCGTTCTACTTTTATG
AGGAAGCGGTCTGGCCGGAGTACTCCCCCAAGCAGATCAACGTGACCGACCGCGCCACGATCCTGAACTTCATCATCGGC
CTCAACGGCTACACGGTGTGCACCGGCATCGACAACGGCGACCTCAACAACGAGAAGATCGTCACCGTGCCGCTCGACAC
CGACGAAACGATGTTGGTCGGCTGGATCACGAACGAGCGTTCCAAGCTCTCCAAGGCCGCCGAAACCTACCTCACCAAGC
TCAAGTCCGTAGTCGCCGATCACGGCTACAAGCTCATTGATTAG

Upstream 100 bases:

>100_bases
CGTCCGCGATATGCGAGGCGTCTCATATTGTGTCGCCATAGTGGATTGATGAGGTTATAAACCCGTGTGGCGACCATCCC
TAGCGATATAAATAGACTTT

Downstream 100 bases:

>100_bases
GAGTAAATAAAACAGGCATGGTCAGCAGTGAGATATACTGCGATTAAGCCAACCCCGCTGGGGAAATGGAAGTAAGAGCC
GGCCCCTGAGTATCTCAGGG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTLLQLKYIVKIVECGSMNEASHALYVSQPALSSSVKELENELGIEIFTRSSQGIALTVDGAEFLTYARQVLDQADLLEE
RYKHAKPRKQLCQVSTQHYMFAVETFVEMISSIKSDEYEFTIRETRTRDIINQVANMQSEIGIIYLSDFNKDVIGKLLRE
KHLEFHPLFRAPLHVFISRNNPLAAKKVITMEDLKPYPFIQYEQGEEGSFYFYEEAVWPEYSPKQINVTDRATILNFIIG
LNGYTVCTGIDNGDLNNEKIVTVPLDTDETMLVGWITNERSKLSKAAETYLTKLKSVVADHGYKLID

Sequences:

>Translated_307_residues
MTLLQLKYIVKIVECGSMNEASHALYVSQPALSSSVKELENELGIEIFTRSSQGIALTVDGAEFLTYARQVLDQADLLEE
RYKHAKPRKQLCQVSTQHYMFAVETFVEMISSIKSDEYEFTIRETRTRDIINQVANMQSEIGIIYLSDFNKDVIGKLLRE
KHLEFHPLFRAPLHVFISRNNPLAAKKVITMEDLKPYPFIQYEQGEEGSFYFYEEAVWPEYSPKQINVTDRATILNFIIG
LNGYTVCTGIDNGDLNNEKIVTVPLDTDETMLVGWITNERSKLSKAAETYLTKLKSVVADHGYKLID
>Mature_306_residues
TLLQLKYIVKIVECGSMNEASHALYVSQPALSSSVKELENELGIEIFTRSSQGIALTVDGAEFLTYARQVLDQADLLEER
YKHAKPRKQLCQVSTQHYMFAVETFVEMISSIKSDEYEFTIRETRTRDIINQVANMQSEIGIIYLSDFNKDVIGKLLREK
HLEFHPLFRAPLHVFISRNNPLAAKKVITMEDLKPYPFIQYEQGEEGSFYFYEEAVWPEYSPKQINVTDRATILNFIIGL
NGYTVCTGIDNGDLNNEKIVTVPLDTDETMLVGWITNERSKLSKAAETYLTKLKSVVADHGYKLID

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787530, Length=217, Percent_Identity=28.110599078341, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=291, Percent_Identity=25.4295532646048, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790262, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787879, Length=205, Percent_Identity=23.9024390243902, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=76, Percent_Identity=40.7894736842105, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788296, Length=225, Percent_Identity=24.8888888888889, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35101; Mature: 34969

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLQLKYIVKIVECGSMNEASHALYVSQPALSSSVKELENELGIEIFTRSSQGIALTVD
CCHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCEEEEEECCCCEEEEEC
GAEFLTYARQVLDQADLLEERYKHAKPRKQLCQVSTQHYMFAVETFVEMISSIKSDEYEF
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TIRETRTRDIINQVANMQSEIGIIYLSDFNKDVIGKLLREKHLEFHPLFRAPLHVFISRN
EEHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCHHHHCCEEEEEECC
NPLAAKKVITMEDLKPYPFIQYEQGEEGSFYFYEEAVWPEYSPKQINVTDRATILNFIIG
CCCCHHEEEEHHCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCEECCHHHHHHHHHHHC
LNGYTVCTGIDNGDLNNEKIVTVPLDTDETMLVGWITNERSKLSKAAETYLTKLKSVVAD
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
HGYKLID
CCEEECC
>Mature Secondary Structure 
TLLQLKYIVKIVECGSMNEASHALYVSQPALSSSVKELENELGIEIFTRSSQGIALTVD
CHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCEEEEEECCCCEEEEEC
GAEFLTYARQVLDQADLLEERYKHAKPRKQLCQVSTQHYMFAVETFVEMISSIKSDEYEF
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TIRETRTRDIINQVANMQSEIGIIYLSDFNKDVIGKLLREKHLEFHPLFRAPLHVFISRN
EEHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCHHHHCCEEEEEECC
NPLAAKKVITMEDLKPYPFIQYEQGEEGSFYFYEEAVWPEYSPKQINVTDRATILNFIIG
CCCCHHEEEEHHCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCEECCHHHHHHHHHHHC
LNGYTVCTGIDNGDLNNEKIVTVPLDTDETMLVGWITNERSKLSKAAETYLTKLKSVVAD
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
HGYKLID
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]