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The map label for this gene is pgsA1 [H]

Identifier: 213692245

GI number: 213692245

Start: 1533618

End: 1534640

Strand: Reverse

Name: pgsA1 [H]

Synonym: Blon_1365

Alternate gene names: 213692245

Gene position: 1534640-1533618 (Counterclockwise)

Preceding gene: 213692246

Following gene: 213692244

Centisome position: 54.17

GC content: 56.4

Gene sequence:

>1023_bases
ATGACCAACCAGAAAGTCAACGCCAGATACAGTCCGGAAGCACGTGACATCTATTTCACTGTGCCCAATTTGATCAGCGC
GCTGCGAATCATCTCGATTCCTTTCATCAGCGTGCTGATCTCCAAGCACGAGATGATTGCGGCGTTAGCCCTGATCGCCA
TTTCCTCGGCTTCAGACGGACTTGACGGCATCATCGCGCGCAGATTCAACCAAGTGAGCAAGATCGGTCAGATTCTTGAT
CCGATCGCCGACCGACTGCTCATTTTCTGCTCGATTCTGGCTCTCAGCGTCGCCGGCATCATCCCATGGTGGATGCTGAT
TATCGTGGGACTGAGGGATCTGTGGATGGCGATTCAGGTGCTATGGCTTGCCCAGTACGGTTATGGCCCGCTGCCCGTGC
ATTTCGTGGGCAAGGCCGGTACCGCGCTGCTGATGATTTCCATCGTCGGTCTGATTTTCGCCGATTTGGGCACCAGTACG
TTCTTCCACTTGCTCTACATCGCCGCGCTGGCCGCCGGCATCTGGGGCATCGCCATGTATTGGCTCGCCGGATATATCTA
TACCAAGCAGGGCGTCGGATTGCTACGCAAGGAACTGGGGGGAGAAGTATGGCGCTTGAGGCCACGGCCCCGGTCTCATT
CCCCGTACCTAAGGAGACTGAGCCGGTACGACGCCGCGCCGTGTTCTCCCACTCAGTCCGAGGCGCGGAATCACATCATG
CGCTTTCCCCGGATGACGCCGCCGCCATCCGCACCCCACGCCGCCGTAAAACCAACGACGATTCGCTTCAGCTCATCGAT
GATCTTGTCAATCGTCCGATGGATCCGATGTTCTCCGACTCACGACTGGTCCATGAGCATCGTTCGACCTTCTCCATCTG
GTTTAATCGCATCGTCGTATTCATCATCTGCGTCGGCGTTGGCTTTGCCTGCAGCCTATTCGTGCAACAGTTGCAATCCG
ATCCGCGTAAGCAGGTACGGCAGACTTTGGCCACGCAATTGGAGAATCGCAACTCGCAAATAG

Upstream 100 bases:

>100_bases
GCCAAGGTCAACCAGCTGATGGATGATTTGTACGAAGTCGGCGCACGCGGCATCATCGTTACCGCTCTGCAAGCCTCCCG
CATGTAGACTGTTAGTCGAT

Downstream 100 bases:

>100_bases
ACGAACTCACCAAGGACGTCAATAATTTGCGCTCCCAAGTTGACGAACAGTCCAAGAAAATCTCCGGCAGCGTGAAAAGC
GATACGCTTATCCAAGACGA

Product: CDP-alcohol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTNQKVNARYSPEARDIYFTVPNLISALRIISIPFISVLISKHEMIAALALIAISSASDGLDGIIARRFNQVSKIGQILD
PIADRLLIFCSILALSVAGIIPWWMLIIVGLRDLWMAIQVLWLAQYGYGPLPVHFVGKAGTALLMISIVGLIFADLGTST
FFHLLYIAALAAGIWGIAMYWLAGYIYTKQGVGLLRKELGGEVWRLRPRPRSHSPYLRRLSRYDAAPCSPTQSEARNHIM
RFPRMTPPPSAPHAAVKPTTIRFSSSMILSIVRWIRCSPTHDWSMSIVRPSPSGLIASSYSSSASALALPAAYSCNSCNP
IRVSRYGRLWPRNWRIATRK

Sequences:

>Translated_340_residues
MTNQKVNARYSPEARDIYFTVPNLISALRIISIPFISVLISKHEMIAALALIAISSASDGLDGIIARRFNQVSKIGQILD
PIADRLLIFCSILALSVAGIIPWWMLIIVGLRDLWMAIQVLWLAQYGYGPLPVHFVGKAGTALLMISIVGLIFADLGTST
FFHLLYIAALAAGIWGIAMYWLAGYIYTKQGVGLLRKELGGEVWRLRPRPRSHSPYLRRLSRYDAAPCSPTQSEARNHIM
RFPRMTPPPSAPHAAVKPTTIRFSSSMILSIVRWIRCSPTHDWSMSIVRPSPSGLIASSYSSSASALALPAAYSCNSCNP
IRVSRYGRLWPRNWRIATRK
>Mature_339_residues
TNQKVNARYSPEARDIYFTVPNLISALRIISIPFISVLISKHEMIAALALIAISSASDGLDGIIARRFNQVSKIGQILDP
IADRLLIFCSILALSVAGIIPWWMLIIVGLRDLWMAIQVLWLAQYGYGPLPVHFVGKAGTALLMISIVGLIFADLGTSTF
FHLLYIAALAAGIWGIAMYWLAGYIYTKQGVGLLRKELGGEVWRLRPRPRSHSPYLRRLSRYDAAPCSPTQSEARNHIMR
FPRMTPPPSAPHAAVKPTTIRFSSSMILSIVRWIRCSPTHDWSMSIVRPSPSGLIASSYSSSASALALPAAYSCNSCNPI
RVSRYGRLWPRNWRIATRK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI10092647, Length=123, Percent_Identity=34.1463414634146, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788220, Length=150, Percent_Identity=27.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984838, Length=108, Percent_Identity=39.8148148148148, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71984834, Length=108, Percent_Identity=39.8148148148148, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320059, Length=138, Percent_Identity=34.7826086956522, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24650130, Length=105, Percent_Identity=35.2380952380952, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650126, Length=105, Percent_Identity=35.2380952380952, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650128, Length=105, Percent_Identity=35.2380952380952, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 37763; Mature: 37632

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQKVNARYSPEARDIYFTVPNLISALRIISIPFISVLISKHEMIAALALIAISSASDG
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LDGIIARRFNQVSKIGQILDPIADRLLIFCSILALSVAGIIPWWMLIIVGLRDLWMAIQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLAQYGYGPLPVHFVGKAGTALLMISIVGLIFADLGTSTFFHLLYIAALAAGIWGIAMY
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAGYIYTKQGVGLLRKELGGEVWRLRPRPRSHSPYLRRLSRYDAAPCSPTQSEARNHIM
HHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
RFPRMTPPPSAPHAAVKPTTIRFSSSMILSIVRWIRCSPTHDWSMSIVRPSPSGLIASSY
HCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEECCC
SSSASALALPAAYSCNSCNPIRVSRYGRLWPRNWRIATRK
CCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCEEECCC
>Mature Secondary Structure 
TNQKVNARYSPEARDIYFTVPNLISALRIISIPFISVLISKHEMIAALALIAISSASDG
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LDGIIARRFNQVSKIGQILDPIADRLLIFCSILALSVAGIIPWWMLIIVGLRDLWMAIQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLAQYGYGPLPVHFVGKAGTALLMISIVGLIFADLGTSTFFHLLYIAALAAGIWGIAMY
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLAGYIYTKQGVGLLRKELGGEVWRLRPRPRSHSPYLRRLSRYDAAPCSPTQSEARNHIM
HHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
RFPRMTPPPSAPHAAVKPTTIRFSSSMILSIVRWIRCSPTHDWSMSIVRPSPSGLIASSY
HCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEECCC
SSSASALALPAAYSCNSCNPIRVSRYGRLWPRNWRIATRK
CCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]