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The map label for this gene is thrS [H]

Identifier: 213692035

GI number: 213692035

Start: 1334838

End: 1336871

Strand: Direct

Name: thrS [H]

Synonym: Blon_1153

Alternate gene names: 213692035

Gene position: 1334838-1336871 (Clockwise)

Preceding gene: 213692033

Following gene: 213692036

Centisome position: 47.12

GC content: 62.24

Gene sequence:

>2034_bases
ATGGCGCAAGCTACCATCTCCATAACCGTCAACGGCGAAGCGAAGGAGGTGGAAGCAACCACCACCGGCGTAGAACTGTT
CGCGGAAGACAAGAACATCATCGCGGTCAAGATCAACGGCGAAAACCGTGACCTGTACACGCCGCTTGCCGACGGCGACA
CCGTAGAGCCCATCACGCTCGATTCCGAAGACGGCCTCGCGATCATGCGTCACTCAGCCACCCACGTCATGGCCCAGGCC
GTGCAGGAGGTCTATCCGAACGCCAAGCTCGGCGTCGGCCCGGTGATCAAGGACGGCTTCTACTACGATTTCCAGGTTGA
CAAGCCCTTCACCCCGGAAGACCTCAAGGACATCGAGAAGCGCATACAGCGCATCATCAAGTCCTCCCAGTCCTTCCGCC
GCCGGTCCGTGACCGAGGAAGAGGCCCTGAAGGAAGAGGCCGACCAGCCCTTCAAGATCGAGCTGATCGAAGACAAGGAA
GCACACCTCGACCCGGCCGCCGCCACCGAGATTTCCGAGAAGGAACTCAGCTTCTACGACAACGTCGACCGTGACGGCAA
TGTGGTCTGGAAGGACCTGTGCCGCGGCCCGCACCTACCGAACACCCGCTACATCAAGGCTTTCAAGATTGAGCGTTCAG
CCGCTGCCTACTGGCGTGGCAGCGAGAAGAACCCGACCATGCAGCGCATCTACGGCACCGCATGGGCCACCAAGGACGAT
CTCAAGGCATACCAGACCCGTCTGGAGGAGGCCGCCAAGCGCGACCACCGCAAGCTCGGTGCCGAGATGGATCTGTTCTC
CTTCCCGGACGAGATCGGCCCCGGCCTGGCCGTGTTCCACCCGAAGGGTGCCGCCGTGATCAACGCGATGGAGGACTACT
CGCGCGAGATGCACCGCAAGCACCACTACAGCTTCGTGCAGACCCCGCACATCACCAAGGGCGGCCTGTACGAGACCTCC
GGTCACCTGCACTGGTACAAGGATGGCATGTACCCGGCCATGCACCTCGACGAGGAGTACGACGCGGACGGCAACGTGAC
CAAGCCCGGCTTCGACTACTACCTCAAGCCGATGAACTGCCCGATGCACAACCTGATCTTCAAGTCGCGCCAGCGCTCCT
ACCGTGAGCTGCCGCTGCGCCTCTTCGAGTTCGGTACCGTGTACCGCTACGAGAAGTCCGGCGAGGTCCATGGCCTGACC
CGTGTGCGTGGCTTGACTCAGGACGATTCCCACATCTACTGCACCCGCGAGCAGATGAAGGACGAGCTGACCAGCCTGCT
GACCTTCGTGCTGAATCTGCTCAAGGACTTCGGTCTGTCCGACTTCTACTTGGAGCTCTCCACCAAGGATCCGGACAAGT
ACGTCGGCTCCGACGAGATCTGGGAGGAGGCCACCCGTACCCTGCGTGAGGTCGCCGAGGCATCCCACCTCGACCTCGTG
GCCGATCCGGGCGGGGCCGCCTTCTACGGCCCGAAGATCTCCGTGCAGGCCCGTGACGCCATCGGCCGTACTTGGCAGGT
CTCGACCATCCAGCTCGACTTCAACCTGCCCGAGCGTTTCCAGCTTGAGTACATCGCGAAGGACGGCACCCATCAGCGTC
CGGTGATGATTCACCGCGCCCTGTTCGGCTCCATCGAACGCTTCTTCGCCGTGCTGCTCGAGCACTACGCTGGCGCCTTC
CCGGCGTGGCTGGCCCCCGTGCAGGTGCTCGGCGTGCCGGTTGCCGACGAGTTCGCCCCGCATCTGGCCGGTTTCGTCAA
GTCCCTCGAGGATGAGATGGTCCGTTGCGAGATCGACTACTCCGATGACCGCTTCGGCAAGAAGATTCGCAACGCCTCCA
AGTCCAAGGTGCCGTTCATCCTCATCGTCGGTGAGGAAGACATGAACAACAACGCGGTGAGCTTCCGCTTCCGCGACGGC
AGCCAGCTCAACGGCGTACCGGTGGACAAGGCTCGCGAGCAGATCCTCGCCGTGATCGCCAAGCGCGTCCAGGTGAACTC
CGCCGACGACTTCAACGCCGCTGTAGCTGAGTAA

Upstream 100 bases:

>100_bases
GGTGGTATTTGTCGTACGCCCAACCTATCGTGTCCTACGTTGATTAACCAGTCCAGGCCTGCACATTAGTACCGCGGGCC
CCGATAGCAAAGGACAGATC

Downstream 100 bases:

>100_bases
AGGAATACATGATGGCTGACGTGCGTGTCGATGATCCGGCGGACTTCCCGCCTCAGGAAGACACGGTCGAACGACTGTGG
ACCCCGCAGCGCATGACCTA

Product: threonyl-tRNA synthetase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MAQATISITVNGEAKEVEATTTGVELFAEDKNIIAVKINGENRDLYTPLADGDTVEPITLDSEDGLAIMRHSATHVMAQA
VQEVYPNAKLGVGPVIKDGFYYDFQVDKPFTPEDLKDIEKRIQRIIKSSQSFRRRSVTEEEALKEEADQPFKIELIEDKE
AHLDPAAATEISEKELSFYDNVDRDGNVVWKDLCRGPHLPNTRYIKAFKIERSAAAYWRGSEKNPTMQRIYGTAWATKDD
LKAYQTRLEEAAKRDHRKLGAEMDLFSFPDEIGPGLAVFHPKGAAVINAMEDYSREMHRKHHYSFVQTPHITKGGLYETS
GHLHWYKDGMYPAMHLDEEYDADGNVTKPGFDYYLKPMNCPMHNLIFKSRQRSYRELPLRLFEFGTVYRYEKSGEVHGLT
RVRGLTQDDSHIYCTREQMKDELTSLLTFVLNLLKDFGLSDFYLELSTKDPDKYVGSDEIWEEATRTLREVAEASHLDLV
ADPGGAAFYGPKISVQARDAIGRTWQVSTIQLDFNLPERFQLEYIAKDGTHQRPVMIHRALFGSIERFFAVLLEHYAGAF
PAWLAPVQVLGVPVADEFAPHLAGFVKSLEDEMVRCEIDYSDDRFGKKIRNASKSKVPFILIVGEEDMNNNAVSFRFRDG
SQLNGVPVDKAREQILAVIAKRVQVNSADDFNAAVAE

Sequences:

>Translated_677_residues
MAQATISITVNGEAKEVEATTTGVELFAEDKNIIAVKINGENRDLYTPLADGDTVEPITLDSEDGLAIMRHSATHVMAQA
VQEVYPNAKLGVGPVIKDGFYYDFQVDKPFTPEDLKDIEKRIQRIIKSSQSFRRRSVTEEEALKEEADQPFKIELIEDKE
AHLDPAAATEISEKELSFYDNVDRDGNVVWKDLCRGPHLPNTRYIKAFKIERSAAAYWRGSEKNPTMQRIYGTAWATKDD
LKAYQTRLEEAAKRDHRKLGAEMDLFSFPDEIGPGLAVFHPKGAAVINAMEDYSREMHRKHHYSFVQTPHITKGGLYETS
GHLHWYKDGMYPAMHLDEEYDADGNVTKPGFDYYLKPMNCPMHNLIFKSRQRSYRELPLRLFEFGTVYRYEKSGEVHGLT
RVRGLTQDDSHIYCTREQMKDELTSLLTFVLNLLKDFGLSDFYLELSTKDPDKYVGSDEIWEEATRTLREVAEASHLDLV
ADPGGAAFYGPKISVQARDAIGRTWQVSTIQLDFNLPERFQLEYIAKDGTHQRPVMIHRALFGSIERFFAVLLEHYAGAF
PAWLAPVQVLGVPVADEFAPHLAGFVKSLEDEMVRCEIDYSDDRFGKKIRNASKSKVPFILIVGEEDMNNNAVSFRFRDG
SQLNGVPVDKAREQILAVIAKRVQVNSADDFNAAVAE
>Mature_676_residues
AQATISITVNGEAKEVEATTTGVELFAEDKNIIAVKINGENRDLYTPLADGDTVEPITLDSEDGLAIMRHSATHVMAQAV
QEVYPNAKLGVGPVIKDGFYYDFQVDKPFTPEDLKDIEKRIQRIIKSSQSFRRRSVTEEEALKEEADQPFKIELIEDKEA
HLDPAAATEISEKELSFYDNVDRDGNVVWKDLCRGPHLPNTRYIKAFKIERSAAAYWRGSEKNPTMQRIYGTAWATKDDL
KAYQTRLEEAAKRDHRKLGAEMDLFSFPDEIGPGLAVFHPKGAAVINAMEDYSREMHRKHHYSFVQTPHITKGGLYETSG
HLHWYKDGMYPAMHLDEEYDADGNVTKPGFDYYLKPMNCPMHNLIFKSRQRSYRELPLRLFEFGTVYRYEKSGEVHGLTR
VRGLTQDDSHIYCTREQMKDELTSLLTFVLNLLKDFGLSDFYLELSTKDPDKYVGSDEIWEEATRTLREVAEASHLDLVA
DPGGAAFYGPKISVQARDAIGRTWQVSTIQLDFNLPERFQLEYIAKDGTHQRPVMIHRALFGSIERFFAVLLEHYAGAFP
AWLAPVQVLGVPVADEFAPHLAGFVKSLEDEMVRCEIDYSDDRFGKKIRNASKSKVPFILIVGEEDMNNNAVSFRFRDGS
QLNGVPVDKAREQILAVIAKRVQVNSADDFNAAVAE

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI38570111, Length=668, Percent_Identity=37.2754491017964, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI38202255, Length=614, Percent_Identity=38.9250814332248, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI20070344, Length=680, Percent_Identity=35.1470588235294, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI1788013, Length=634, Percent_Identity=37.5394321766561, Blast_Score=480, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI71984184, Length=622, Percent_Identity=36.4951768488746, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71984192, Length=622, Percent_Identity=36.4951768488746, Blast_Score=399, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322112, Length=643, Percent_Identity=37.9471228615863, Blast_Score=413, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322654, Length=453, Percent_Identity=34.6578366445916, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24583842, Length=610, Percent_Identity=38.1967213114754, Blast_Score=425, Evalue=1e-119,
Organism=Drosophila melanogaster, GI28574141, Length=610, Percent_Identity=38.1967213114754, Blast_Score=425, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24583839, Length=610, Percent_Identity=38.1967213114754, Blast_Score=425, Evalue=1e-119,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 76820; Mature: 76689

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQATISITVNGEAKEVEATTTGVELFAEDKNIIAVKINGENRDLYTPLADGDTVEPITL
CCCEEEEEEECCCCCEEEEECCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCEEEE
DSEDGLAIMRHSATHVMAQAVQEVYPNAKLGVGPVIKDGFYYDFQVDKPFTPEDLKDIEK
CCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEEECCCCCHHHHHHHHH
RIQRIIKSSQSFRRRSVTEEEALKEEADQPFKIELIEDKEAHLDPAAATEISEKELSFYD
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHC
NVDRDGNVVWKDLCRGPHLPNTRYIKAFKIERSAAAYWRGSEKNPTMQRIYGTAWATKDD
CCCCCCCCHHHHHHCCCCCCCCCEEEEEEEECHHHHHCCCCCCCCHHHHHHHHHCCCHHH
LKAYQTRLEEAAKRDHRKLGAEMDLFSFPDEIGPGLAVFHPKGAAVINAMEDYSREMHRK
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
HHYSFVQTPHITKGGLYETSGHLHWYKDGMYPAMHLDEEYDADGNVTKPGFDYYLKPMNC
HCCCCCCCCCCCCCCCEECCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEECCCCC
PMHNLIFKSRQRSYRELPLRLFEFGTVYRYEKSGEVHGLTRVRGLTQDDSHIYCTREQMK
CHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCHHHHCCCCCCCCEEEEEHHHHH
DELTSLLTFVLNLLKDFGLSDFYLELSTKDPDKYVGSDEIWEEATRTLREVAEASHLDLV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHCCCEEE
ADPGGAAFYGPKISVQARDAIGRTWQVSTIQLDFNLPERFQLEYIAKDGTHQRPVMIHRA
ECCCCCEEECCEEEEEEHHCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHH
LFGSIERFFAVLLEHYAGAFPAWLAPVQVLGVPVADEFAPHLAGFVKSLEDEMVRCEIDY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECC
SDDRFGKKIRNASKSKVPFILIVGEEDMNNNAVSFRFRDGSQLNGVPVDKAREQILAVIA
CCHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
KRVQVNSADDFNAAVAE
HHHCCCCCCCCCHHCCC
>Mature Secondary Structure 
AQATISITVNGEAKEVEATTTGVELFAEDKNIIAVKINGENRDLYTPLADGDTVEPITL
CCEEEEEEECCCCCEEEEECCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCEEEE
DSEDGLAIMRHSATHVMAQAVQEVYPNAKLGVGPVIKDGFYYDFQVDKPFTPEDLKDIEK
CCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEEECCCCCHHHHHHHHH
RIQRIIKSSQSFRRRSVTEEEALKEEADQPFKIELIEDKEAHLDPAAATEISEKELSFYD
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHC
NVDRDGNVVWKDLCRGPHLPNTRYIKAFKIERSAAAYWRGSEKNPTMQRIYGTAWATKDD
CCCCCCCCHHHHHHCCCCCCCCCEEEEEEEECHHHHHCCCCCCCCHHHHHHHHHCCCHHH
LKAYQTRLEEAAKRDHRKLGAEMDLFSFPDEIGPGLAVFHPKGAAVINAMEDYSREMHRK
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
HHYSFVQTPHITKGGLYETSGHLHWYKDGMYPAMHLDEEYDADGNVTKPGFDYYLKPMNC
HCCCCCCCCCCCCCCCEECCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEECCCCC
PMHNLIFKSRQRSYRELPLRLFEFGTVYRYEKSGEVHGLTRVRGLTQDDSHIYCTREQMK
CHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCHHHHCCCCCCCCEEEEEHHHHH
DELTSLLTFVLNLLKDFGLSDFYLELSTKDPDKYVGSDEIWEEATRTLREVAEASHLDLV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHCCCEEE
ADPGGAAFYGPKISVQARDAIGRTWQVSTIQLDFNLPERFQLEYIAKDGTHQRPVMIHRA
ECCCCCEEECCEEEEEEHHCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHH
LFGSIERFFAVLLEHYAGAFPAWLAPVQVLGVPVADEFAPHLAGFVKSLEDEMVRCEIDY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECC
SDDRFGKKIRNASKSKVPFILIVGEEDMNNNAVSFRFRDGSQLNGVPVDKAREQILAVIA
CCHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
KRVQVNSADDFNAAVAE
HHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA